Global DNA hypermethylation is associated with high serum levels of persistent organic pollutants in an elderly population

Environment International

Volumn 59, Issue , 2013, Pages 456-461

  Lind, Lars ^a   Penell, Johanna ^a   Luttropp, Karin ^b   Nordfors, Louise ^b   Syvänen, Anne Christine ^a   Axelsson, Tomas ^a   Salihovic, Samira ^c   van Bavel, Bert ^c   Fall, Tove ^a   Ingelsson, Erik ^a   Lind, P Monica ^a  

^a UPPSALA UNIVERSITY   (Sweden)

^b KAROLINSKA INSTITUTE   (Sweden)

^c ÖREBRO UNIVERSITY   (Sweden)

Author keywords

DNA methylation; Elderly; Persistent organic pollutants

Indexed keywords

ALKYLATION; ASSOCIATION REACTIONS; BODY FLUIDS; DNA SEQUENCES; PESTICIDES; POLYCHLORINATED BIPHENYLS;

BROMINATED FLAME RETARDANTS; CROSS SECTIONAL ANALYSIS; DNA METHYLATION; ELDERLY; ENVIRONMENTAL POLLUTANTS; PERSISTENT ORGANIC POLLUTANT (POP); PESTICIDE METABOLITES; SINGLE NUCLEOTIDE POLYMORPHISMS;

ORGANIC POLLUTANTS;

1,1 DICHLORO 2,2 BIS(4 CHLOROPHENYL)ETHYLENE; 3,3',4,4',5 PENTACHLOROBIPHENYL; AROMATIC HYDROCARBON RECEPTOR; DIOXIN; FLAME RETARDANT; ORGANOCHLORINE PESTICIDE; PESTICIDE; POLYCHLORINATED BIPHENYL;

DIOXIN; DNA; ELDERLY POPULATION; METHYLATION; ORGANIC POLLUTANT; SERUM;

AGED; ARTICLE; ARYL HYDROCARBON RECEPTOR GENE; DNA METHYLATION; FEMALE; HUMAN; MALE; PERSISTENT ORGANIC POLLUTANT; POLLUTANT; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM; TOXIC EQUIVALENCY; TOXICOLOGICAL PARAMETERS;

SWEDEN; UPPSALA [SWEDEN];

2, 2-BIS (4-CHLOROPHENYL)-1, 1-DICHLOROETHENE; 2,3,7,8-TETRACHLORODIBENZO-P-DIOXIN; AH; ARYL HYDROCARBON; BDE; BROMINATED BIPHENYL ETHER; CI; CONFIDENCE INTERVAL; DEOXYRIBONUCLEIC ACID; DNA; DNA METHYLATION; ELDERLY; HARDY-WEINBERG PRINCIPLE; HCB; HEXACHLOROBENZENE; HIGH-RESOLUTION GAS CHROMATOGRAPHY; HIGH-RESOLUTION MASS SPECTROMETRY; HRGC; HRMS; HWP; LUMA; LUMINOMETRIC METHYLATION ASSAY; OC; OCDD; OCTACHLORODIBENZO-P-DIOXIN; ORGANOCHLORINE; P,P′-DDE; PCBS; PERSISTENT ORGANIC POLLUTANTS; PIVUS; POLYCHLORINATED BIPHENYLS; POP; PROSPECTIVE INVESTIGATION OF THE VASCULATURE IN UPPSALA SENIORS; RIBONUCLEIC ACID; RNA; SINGLE NUCLEOTIDE POLYMORPHISM; SNP; TCDD; TEQ; TNC; TOXIC EQUIVALENCY; TRANS-NONACHLORDANE; WHO; WORLD HEALTH ORGANIZATION;

AGED; CROSS-SECTIONAL STUDIES; DICHLORODIPHENYL DICHLOROETHYLENE; DIOXINS; DNA METHYLATION; ENVIRONMENTAL POLLUTANTS; FEMALE; HALOGENATED DIPHENYL ETHERS; HUMANS; MALE; PESTICIDES; POLYCHLORINATED BIPHENYLS; PROSPECTIVE STUDIES; RECEPTORS, ARYL HYDROCARBON; TETRACHLORODIBENZODIOXIN;

EID: 84882716311     PISSN: 01604120     EISSN: 18736750     Source Type: Journal    
DOI: 10.1016/j.envint.2013.07.008     Document Type: Article

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