Cathepsin S from both tumor and tumor-associated cells promote cancer growth and neovascularization

International Journal of Cancer

Volumn 133, Issue 9, 2013, Pages 2102-2112

  Small, Donna M ^a   Burden, Roberta E ^a   Jaworski, Jakub ^a   Hegarty, Shauna M ^b   Spence, Shaun ^a   Burrows, James F ^a   McFarlane, Cheryl ^a   Kissenpfennig, Adrien ^a   McCarthy, Helen O ^a   Johnston, James A ^b,c   Walker, Brian ^a   Scott, Christopher J ^a  

^a QUEEN'S UNIVERSITY BELFAST   (United Kingdom)

^b QUEEN'S UNIVERSITY BELFAST   (United Kingdom)

^c AMGEN INC   (United States)

Author keywords

angiogenesis; cathepsin S; proteases; stroma; tumorigenesis

Indexed keywords

CATHEPSIN S; CATHEPSIN S INHIBITOR; PROTEINASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CANCER GROWTH; CANCER INHIBITION; CELL PROLIFERATION; COLORECTAL CARCINOMA; CONTROLLED STUDY; DRUG TARGETING; ENDOTHELIUM CELL; ENZYME ACTIVITY; LEWIS CARCINOMA; MALE; MELANOMA B16; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN FUNCTION; TUMOR ASSOCIATED LEUKOCYTE; TUMOR CELL LINE; TUMOR VASCULARIZATION;

ANGIOGENESIS; CATHEPSIN S; PROTEASES; STROMA; TUMORIGENESIS;

ANIMALS; APOPTOSIS; BLOTTING, WESTERN; CARCINOMA, LEWIS LUNG; CATHEPSINS; CELL ADHESION; CELL CYCLE; CELL MOVEMENT; CELL PROLIFERATION; CELLS, CULTURED; COLORECTAL NEOPLASMS; ENDOTHELIUM, VASCULAR; FLOW CYTOMETRY; FLUORESCENT ANTIBODY TECHNIQUE; HUMANS; IMMUNOENZYME TECHNIQUES; MACROPHAGES; MELANOMA, EXPERIMENTAL; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NEOVASCULARIZATION, PATHOLOGIC; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TUMOR MICROENVIRONMENT;

EID: 84882630715     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.28238     Document Type: Article

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