High-throughput screening of radioprotectors using rat thymocytes

Analytical Chemistry

Volumn 85, Issue 16, 2013, Pages 7650-7653

  Sekine Suzuki, Emiko ^a   Nakanishi, Ikuo ^a   Shimokawa, Takashi ^a   Ueno, Megumi ^a   Matsumoto, Ken Ichiro ^a   Murakami, Takeshi ^a  

^a NATIONAL INSTITUTE OF RADIOLOGICAL SCIENCES   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CELL-SHRINKAGE; FLOW CYTOMETRY ANALYSIS; HIGH-THROUGHPUT SCREENING; INDUCED APOPTOSIS; NATURAL ANTIOXIDANTS; PROTECTIVE EFFECTS; RADIATION-INDUCED APOPTOSIS; RADIOPROTECTORS;

IRRADIATION; TOXICITY;

RATS;

EID: 84882607029     PISSN: 00032700     EISSN: 15206882     Source Type: Journal    
DOI: 10.1021/ac401903h     Document Type: Article

References (10)

1. JASTRO (Japanese Society for Therapeutic Radiology and Oncology), Report; JASTRO (Japanese Society for Therapeutic Radiology and Oncology), 2005.
2. Weiss, J. F.; Landauer, M. R. Int. J. Radiat. Biol. 2009, 85, 539-573 and references cited therein.
3. Radioprotectors: Chemical, Biological, and Clinical Perspectives; Bump, E. A.; Malaker, K., Eds.; CRC Press: Boca Raton, FL, 1997.
4. Hosseinimehr, S. J. Drug Discovery Today 2007, 12, 794-805
5. Kouvaris, J. R.; Kouloulias, V. E.; Vlahos, L. J. Oncologist 2007, 12, 738-747
6. Maurya, D. K.; Nair, C. K.; Devasagayam, T. P. Mutat. Res. 2012, 74, 993-996
7. Ohyama, H.; Yamada, T.; Watanabe, I. Radiat. Res. 1981, 85, 333-339
8. Yamada, T.; Ohyama, H. Int. J. Radiat. Biol. 1988, 53, 65-75
9. Ohyama, H.; Yamada, T.; Ohkawa, A.; Watanabe, I. Radiat. Res. 1985, 101, 123-130
10. This method is under evaluation for a patent in Japan (No. 2012-72619) and PCT patent (PCT/JP2013/002032).