A new role for the cellular PABP repressor Paip2 as an innate restriction factor capable of limiting productive cytomegalovirus replication

Genes and Development

Volumn 27, Issue 16, 2013, Pages 1809-1820

  McKinney, Caleb ^a   Yu, Dong ^b   Mohr, Ian ^a  

^a NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

HCMV replication; Innate defense; mTORC1; PABP; Paip2; Translation control

Indexed keywords

MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; POLYADENYLIC ACID BINDING PROTEIN; PROTEIN; PROTEIN EDD1; PROTEIN PAIP2; PROTEIN UL38; TRANSLATION INITIATION FACTOR EIF4F; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG; VIRUS PROTEIN;

ARTICLE; CELL FUNCTION; CONTROLLED STUDY; CYTOMEGALOVIRUS; FIBROBLAST; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN STABILITY; PROTEIN SYNTHESIS; PROTEIN SYNTHESIS INHIBITION; TRANSLATION REGULATION; VIRUS INHIBITION; VIRUS REPLICATION;

HCMV REPLICATION; INNATE DEFENSE; MTORC1; PABP; PAIP2; TRANSLATION CONTROL;

CELL LINE; CYTOMEGALOVIRUS; CYTOMEGALOVIRUS INFECTIONS; GENE EXPRESSION REGULATION; HUMANS; MULTIPROTEIN COMPLEXES; PROTEIN BINDING; PROTEIN STABILITY; REPRESSOR PROTEINS; RNA, MESSENGER; RNA-BINDING PROTEINS; TOR SERINE-THREONINE KINASES; UBIQUITIN-PROTEIN LIGASES; VIRUS REPLICATION;

EID: 84882593141     PISSN: 08909369     EISSN: 15495477     Source Type: Journal    
DOI: 10.1101/gad.221341.113     Document Type: Article

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