miRNA-218 inhibits osteosarcoma cell migration and invasion by down-regulating of TIAM1, MMP2 and MMP9

Asian Pacific Journal of Cancer Prevention

Volumn 14, Issue 6, 2013, Pages 3681-3684

  Jin, Jie ^a   Cai, Lin ^a   Liu, Zhi Ming ^b   Zhou, Xue Song ^b  

^a ZHONGNAN HOSPITAL OF WUHAN UNIVERSITY   (China)

^b TONGREN HOSPITAL OF WUHAN UNIVERSITY   (China)

Author keywords

Invasion; Migration; MiRNA 218; MMP; Osteosarcoma; Proliferation; TIAM1

Indexed keywords

EID: 84882589945     PISSN: 15137368     EISSN: 2476762X     Source Type: Journal    
DOI: 10.7314/APJCP.2013.14.6.3681     Document Type: Article

References (19)

1. Alajez NM, Lenarduzzi M, Ito E, et al (2011). MiR-218 suppresses nasopharyngeal cancer progression through downregulation of survivin and the SLIT2-ROBO1 pathway. Cancer Res, 71, 2381-91.
2. Dieckmann KP, Spiekermann M, Balks T, et al (2012). MicroRNAs miR-371-3 in serum as diagnostic tools in the management of testicular germ cell tumours. Br J Cancer, 107, 1754-60.
3. Habets GG, Scholtes EH, Zuydgeest D, et al (1994). Identification of an invasion-inducing gene, Tiam-1, that encodes a protein with homology to GDP-GTP exchangers for Rho-like proteins. Cell, 77, 537-49.
4. He X, Dong Y, Wu CW, et al (2013). MicroRNA-218 inhibits cell cycle progression and promotes apoptosis in colon cancer by downregulating BMI1 polycomb ring finger oncogene. Mol Med, 18, 1491-8.
5. Hagman Z, Haflidadóttir BS, Ceder JA, et al (2013). miR-205 negatively regulates the androgen receptor and is associated with adverse outcome of prostate cancer patients. Br J Cancer, 108, 1668-76.
6. Jin Y, Peng D, Shen Y, et al (2013). MicroRNA-376c Inhibits Cell Proliferation and Invasion in Osteosarcoma by Targeting to Transforming Growth Factor-Alpha. DNA Cell Biol, 32, 302-9.
7. Kawauchi T, Chihama K, Nabeshima Y, et al (2003). The in vivo roles of STEF/Tiam1, Rac1 and JNK in cortical neuronal migration. EMBO J, 22, 4190-201.
8. Kinoshita T, Hanazawa T, Nohata N, et al (2012). Tumor suppressive microRNA-218 inhibits cancer cell migration and invasion through targeting laminin-332 in head and neck squamous cell carcinoma. Oncotarget, 3, 1386-400.
9. Li J, Liang S, Jin H, et al (2012). Tiam1, negatively regulated by miR-22, miR-183 and miR-31, is involved in migration, invasion and viability of ovarian cancer cells. Oncol Rep, 27, 1835-42.
10. Liu Y, Yan W, Zhang W, et al (2012). MiR-218 reverses high invasiveness of glioblastoma cells by targeting the oncogenic transcription factor LEF1. Oncol Rep, 28, 1013-21.
11. Long XH, Mao JH, Peng AF, et al (2013). Tumor suppressive microRNA-424 inhibits osteosarcoma cell migration and invasion via targeting fatty acid synthase. Exp Ther Med, 5, 1048-52.
12. Mao JH, Zhou RP, Peng AF, et al (2012). microRNA-195 suppresses osteosarcoma cell invasion and migration in vitro by targeting FASN. Oncol Lett, 4, 1125-29.
13. Nana-Sinkam SP, Croce CM (2013). Clinical applications for microRNAs in cancer. Clin Pharmacol Ther, 93, 98-104.
14. Ottaviani G, Jaffe N (2009). The epidemiology of osteosarcoma. Cancer Treat Res, 152, 3-13.
15. Osman A (2012). MicroRNAs in health and disease--basic science and clinical applications. Clin Lab, 58, 393-402.
16. Qin S, Ai F, Ji WF, et al (2013). miR-19a Promotes Cell Growth and Tumorigenesis through Targeting SOCS1 in GastricCancer. Asian Pac J Cancer Prev, 14, 835-40.
17. Takahashi M, Cuatrecasas M, Balaguer F, et al (2012). The clinical significance of MiR-148a as a predictive biomarker in patients with advanced colorectal cancer. PLoS One, 7, e46684.
18. Venkataraman S, Birks DK, Balakrishnan I, et al (2013). MicroRNA 218 acts as a tumor suppressor by targeting multiple cancer phenotype-associated genes in medulloblastoma. J Biol Chem, 288, 1918-28.
19. Wu X, Zhong D, Gao Q, et al (2013). MicroRNA-34a Inhibits Human Osteosarcoma Proliferation by Downregulating Ether à go-go 1 Expression. Int J Med Sci, 10, 676-82.