메뉴 건너뛰기




Volumn , Issue , 2009, Pages 35-48

Development of Recombinant Erythropoietin and Erythropoietin Analogs

Author keywords

[No Author keywords available]

Indexed keywords


EID: 84882499498     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1016/B978-0-12-373870-7.00004-1     Document Type: Chapter
Times cited : (1)

References (108)
  • 1
    • 0029348847 scopus 로고
    • Effect of low dose recombinant human omega erythropoietin (rHuEPO) on anaemia in patients on hemodialysis
    • Acharya V.N., Sinha D.K., Almeida A.F., Pathare A.V. Effect of low dose recombinant human omega erythropoietin (rHuEPO) on anaemia in patients on hemodialysis. J Assoc Physicians India 1995, 43:539-542.
    • (1995) J Assoc Physicians India , vol.43 , pp. 539-542
    • Acharya, V.N.1    Sinha, D.K.2    Almeida, A.F.3    Pathare, A.V.4
  • 2
    • 33750501617 scopus 로고    scopus 로고
    • An open-label study of darbepoetin alfa administered once monthly for the maintenance of haemoglobin concentrations in patients with chronic kidney disease not receiving dialysis
    • Agarwal A.K., Silver M.R., Reed J.E., et al. An open-label study of darbepoetin alfa administered once monthly for the maintenance of haemoglobin concentrations in patients with chronic kidney disease not receiving dialysis. J Intern Med 2006, 260:577-585.
    • (2006) J Intern Med , vol.260 , pp. 577-585
    • Agarwal, A.K.1    Silver, M.R.2    Reed, J.E.3
  • 3
    • 84882541853 scopus 로고    scopus 로고
    • Aranesp (darbepoetin alfa) administered every 2 weeks (Q2W) effectively maintains haemoglobin in patients receiving peritoneal dialysis: results of a pooled analysis of eight European studies.
    • Paper presented at 42nd ERA-EDTA Congress, Istanbul, Turkey.
    • Barril, G., Montenegro, J., Ronco, C. et al. (2005). Aranesp (darbepoetin alfa) administered every 2 weeks (Q2W) effectively maintains haemoglobin in patients receiving peritoneal dialysis: results of a pooled analysis of eight European studies. Paper presented at 42nd ERA-EDTA Congress, Istanbul, Turkey.
    • (2005)
    • Barril, G.1    Montenegro, J.2    Ronco, C.3
  • 4
    • 0032572913 scopus 로고    scopus 로고
    • The effects of normal as compared with low hematocrit values in patients with cardiac disease who are receiving hemodialysis and epoetin
    • Besarab A., Kline Bolton W., Browne J.K., et al. The effects of normal as compared with low hematocrit values in patients with cardiac disease who are receiving hemodialysis and epoetin. N Engl J Med 1998, 339:584-590.
    • (1998) N Engl J Med , vol.339 , pp. 584-590
    • Besarab, A.1    Kline Bolton, W.2    Browne, J.K.3
  • 5
    • 0036724273 scopus 로고    scopus 로고
    • Meta-analysis of subcutaneous versus intravenous epoetin in maintenance treatment of anemia in hemodialysis patients
    • Besarab A., Reyes C.M., Hornberger J. Meta-analysis of subcutaneous versus intravenous epoetin in maintenance treatment of anemia in hemodialysis patients. Am J Kidney Dis 2002, 40:439-446.
    • (2002) Am J Kidney Dis , vol.40 , pp. 439-446
    • Besarab, A.1    Reyes, C.M.2    Hornberger, J.3
  • 6
    • 84882543337 scopus 로고    scopus 로고
    • on behalf of the BA16285 study group.
    • Intravenous CERA (Continuous Erythropoietin Receptor activator) administered once weekly or once every 2 weeks maintains haemoglobin levels in haemodialysis patients with chronic renal anaemia. Abstract Book of the XLI Congress of the ERA-EDTA 230: (Abstract M047).
    • Besarab, A., Bansal, V., Fishbane, S. et al. on behalf of the BA16285 study group. (2004). Intravenous CERA (Continuous Erythropoietin Receptor activator) administered once weekly or once every 2 weeks maintains haemoglobin levels in haemodialysis patients with chronic renal anaemia. Abstract Book of the XLI Congress of the ERA-EDTA 230: (Abstract M047).
    • (2004)
    • Besarab, A.1    Bansal, V.2    Fishbane, S.3
  • 7
    • 84882545715 scopus 로고    scopus 로고
    • Hematide, a synthetic peptide-based erythropoiesis stimulating agent, maintains hemoglobin in hemodialysis patients previously treated with epoetin alfa (EPO)
    • Natl Kidney Found Clin Meet 2007, Abs 24.
    • Besarab, A., Zeig, S., Geronemus, R. et al. (2007). Hematide, a synthetic peptide-based erythropoiesis stimulating agent, maintains hemoglobin in hemodialysis patients previously treated with epoetin alfa (EPO). Natl Kidney Found Clin Meet 2007, Abs 24.
    • (2007)
    • Besarab, A.1    Zeig, S.2    Geronemus, R.3
  • 8
    • 84882460588 scopus 로고    scopus 로고
    • Conversion from weekly epoetin to bi-weekly darbepoetin-α maintains hemoglobin and permits dose reductions at higher doses. Results from a prospective study
    • EFIXNES Study Investigators., Paper presented at 42nd ERA-EDTA Congress, Istanbul, Turkey.
    • Bock, A; EFIXNES Study Investigators. (2005). Conversion from weekly epoetin to bi-weekly darbepoetin-α maintains hemoglobin and permits dose reductions at higher doses. Results from a prospective study. Paper presented at 42nd ERA-EDTA Congress, Istanbul, Turkey.
    • (2005)
    • Bock A1
  • 9
    • 19044392727 scopus 로고    scopus 로고
    • The increased incidence of pure red cell aplasia with an Eprex formulation in uncoated rubber stopper syringes
    • Boven K., Stryker S., Knight J., et al. The increased incidence of pure red cell aplasia with an Eprex formulation in uncoated rubber stopper syringes. Kidney Int 2005, 67:2346-2353.
    • (2005) Kidney Int , vol.67 , pp. 2346-2353
    • Boven, K.1    Stryker, S.2    Knight, J.3
  • 10
    • 0036125372 scopus 로고    scopus 로고
    • A comparison between epoetin omega and epoetin alfa in the correction of anemia in hemodialysis patients: a prospective, controlled crossover study
    • Bren A., Kandus A., Varl J., Buturovic J., Ponikvar R., Kveder R. A comparison between epoetin omega and epoetin alfa in the correction of anemia in hemodialysis patients: a prospective, controlled crossover study. Artif Organs 2002, 26:91-97.
    • (2002) Artif Organs , vol.26 , pp. 91-97
    • Bren, A.1    Kandus, A.2    Varl, J.3    Buturovic, J.4    Ponikvar, R.5    Kveder, R.6
  • 11
    • 33846965023 scopus 로고    scopus 로고
    • Pharmacokinetics and pharmacodynamics of CTNO528, a novel erythropoiesis receptor agonist in normal & anemic rats
    • Bugelski P., Nesspor B.T., Spinka-Doms T., et al. Pharmacokinetics and pharmacodynamics of CTNO528, a novel erythropoiesis receptor agonist in normal & anemic rats. Blood 2005, 106:146b.
    • (2005) Blood , vol.106
    • Bugelski, P.1    Nesspor, B.T.2    Spinka-Doms, T.3
  • 12
    • 84882532855 scopus 로고    scopus 로고
    • Intravenous (IV) C.E.R.A. (continuous erythropoietin receptor activator) administered once every 2 weeks maintains stable haemoglobin levels in patients with chronic kidney disease on dialysis [abstract no SP425]. Nephrol Dial Transplant21: iv 157.
    • Canaud, B., Braun, J., Locatelli, F. et al. (2006). Intravenous (IV) C.E.R.A. (continuous erythropoietin receptor activator) administered once every 2 weeks maintains stable haemoglobin levels in patients with chronic kidney disease on dialysis [abstract no SP425]. Nephrol Dial Transplant21: iv 157.
    • (2006)
    • Canaud, B.1    Braun, J.2    Locatelli, F.3
  • 13
    • 0024575860 scopus 로고
    • Designing CD4 immunoadhesins for AIDS therapy
    • Capon D.J., Chamow S.M., Mordenti J., et al. Designing CD4 immunoadhesins for AIDS therapy. Nature 1989, 337:525-531.
    • (1989) Nature , vol.337 , pp. 525-531
    • Capon, D.J.1    Chamow, S.M.2    Mordenti, J.3
  • 14
    • 0000909936 scopus 로고
    • Sur l'activite hemopoietique du serum au cours de la regeneration du sang
    • Carnot P., Deflandre C.L. Sur l'activite hemopoietique du serum au cours de la regeneration du sang. C R Seances Acad Sci. 1906, 143:384-386.
    • (1906) C R Seances Acad Sci. , vol.143 , pp. 384-386
    • Carnot, P.1    Deflandre, C.L.2
  • 15
    • 0037075272 scopus 로고    scopus 로고
    • Pure red-cell aplasia and antierythropoietin antibodies in patients treated with recombinant erythropoietin
    • Casadevall N., Nataf J., Viron B., et al. Pure red-cell aplasia and antierythropoietin antibodies in patients treated with recombinant erythropoietin. N Engl J Med 2002, 346:469-475.
    • (2002) N Engl J Med , vol.346 , pp. 469-475
    • Casadevall, N.1    Nataf, J.2    Viron, B.3
  • 16
    • 20144371341 scopus 로고    scopus 로고
    • Synthetic erythropoietic proteins: tuning biological performance by site-specific polymer attachment
    • Chen S.Y., Cressman S., Mao F., Shao H., Low D.W., Beilan H.S. Synthetic erythropoietic proteins: tuning biological performance by site-specific polymer attachment. Chem Biol 2005, 12:371-383.
    • (2005) Chem Biol , vol.12 , pp. 371-383
    • Chen, S.Y.1    Cressman, S.2    Mao, F.3    Shao, H.4    Low, D.W.5    Beilan, H.S.6
  • 17
    • 0031756695 scopus 로고    scopus 로고
    • Pharmacokinetic and immunogenic behavior of three recombinant human GM-CSF-EPO hybrid proteins in cynomolgus monkeys
    • Coscarella A., Liddi R., Bach S., et al. Pharmacokinetic and immunogenic behavior of three recombinant human GM-CSF-EPO hybrid proteins in cynomolgus monkeys. Mol Biotechnol 1998, 10:115-122.
    • (1998) Mol Biotechnol , vol.10 , pp. 115-122
    • Coscarella, A.1    Liddi, R.2    Bach, S.3
  • 18
    • 0032469128 scopus 로고    scopus 로고
    • The rhGM-CSF-EPO hybrid protein MEN 11300 induces anti-EPO antibodies and severe anaemia in rhesus monkeys
    • Coscarella A., Liddi R., Di Loreto M., et al. The rhGM-CSF-EPO hybrid protein MEN 11300 induces anti-EPO antibodies and severe anaemia in rhesus monkeys. Cytokine 1998, 10:964-969.
    • (1998) Cytokine , vol.10 , pp. 964-969
    • Coscarella, A.1    Liddi, R.2    Di Loreto, M.3
  • 19
    • 0035877998 scopus 로고    scopus 로고
    • Dimeric erythropoietin fusion protein with enhanced erythropoietic activity in vitro and in vivo
    • Dalle B., Henri A., Rouyer-Fessard P., Bettan M., Scherman D., Beuzard Y. Dimeric erythropoietin fusion protein with enhanced erythropoietic activity in vitro and in vivo. Blood 2001, 97:3776-3782.
    • (2001) Blood , vol.97 , pp. 3776-3782
    • Dalle, B.1    Henri, A.2    Rouyer-Fessard, P.3    Bettan, M.4    Scherman, D.5    Beuzard, Y.6
  • 20
    • 1542322136 scopus 로고    scopus 로고
    • Subcutaneous CERA (Continuous Erythropoietin Receptor Activator) has potent erythropoietic activity in dialysis patients with chronic renal anemia: an exploratory multiple-dose study.
    • (Abstract SA-FC124)
    • de Francisco A.L., Sulowicz W., Dougherty F.C. Subcutaneous CERA (Continuous Erythropoietin Receptor Activator) has potent erythropoietic activity in dialysis patients with chronic renal anemia: an exploratory multiple-dose study. J Am Soc Nephrol 2003, 14:27A-28A. (Abstract SA-FC124).
    • (2003) J Am Soc Nephrol , vol.14
    • de Francisco, A.L.1    Sulowicz, W.2    Dougherty, F.C.3
  • 21
    • 84882544209 scopus 로고    scopus 로고
    • Aranesp (darbepoetin alfa) administered once monthly (QM) maintains hemoglobin (Hb) levels in chronic kidney disease (CKD) patients
    • Paper presented at 42nd ERA-EDTA Congress, Istanbul, Turkey.
    • Disney, A., de Jersey, P., Kirkland, G. et al. (2005). Aranesp (darbepoetin alfa) administered once monthly (QM) maintains hemoglobin (Hb) levels in chronic kidney disease (CKD) patients. Paper presented at 42nd ERA-EDTA Congress, Istanbul, Turkey.
    • (2005)
    • Disney, A.1    de Jersey, P.2    Kirkland, G.3
  • 22
    • 84983473087 scopus 로고    scopus 로고
    • Safety and tolerability profile of Continuous Erythropoietin Receptor Activator (CERA) with extended dosing intervals in patients with chronic kidney disease on dialysis
    • (Abstract W-PO40130)
    • Dougherty F.C., Beyer U. Safety and tolerability profile of Continuous Erythropoietin Receptor Activator (CERA) with extended dosing intervals in patients with chronic kidney disease on dialysis. Nephrology 2005, 10:A313. (Abstract W-PO40130).
    • (2005) Nephrology , vol.10
    • Dougherty, F.C.1    Beyer, U.2
  • 23
    • 33748150635 scopus 로고    scopus 로고
    • CERA (Continuous Erythropoietin Receptor Activator): Dose-response, pharmacokinetics and tolerability in phase I multiple ascending dose studies
    • (Abstract 6692)
    • Dougherty F.C., Reigner B., Jordan P., Pannier A. CERA (Continuous Erythropoietin Receptor Activator): Dose-response, pharmacokinetics and tolerability in phase I multiple ascending dose studies. J Clin Oncol 2004, 22(Suppl 15):14S. (Abstract 6692).
    • (2004) J Clin Oncol , vol.22 , Issue.SUPPL.15
    • Dougherty, F.C.1    Reigner, B.2    Jordan, P.3    Pannier, A.4
  • 24
    • 33751002326 scopus 로고    scopus 로고
    • Normalization of hemoglobin level in patients with chronic kidney disease and anemia
    • Drueke T.B., Locatelli F., Clyne N., et al. Normalization of hemoglobin level in patients with chronic kidney disease and anemia. N Engl J Med 2006, 335:2071-2084.
    • (2006) N Engl J Med , vol.335 , pp. 2071-2084
    • Drueke, T.B.1    Locatelli, F.2    Clyne, N.3
  • 25
    • 25844528107 scopus 로고    scopus 로고
    • Delivery of an erythropoietin-Fc fusion protein by inhalation in humans through an immunoglobulin transport pathway
    • Dumont J.A., Bitonti A.J., Clark D., Evans S., Pickford M., Newman S.P. Delivery of an erythropoietin-Fc fusion protein by inhalation in humans through an immunoglobulin transport pathway. J Aerosol Med 2005, 18:294-303.
    • (2005) J Aerosol Med , vol.18 , pp. 294-303
    • Dumont, J.A.1    Bitonti, A.J.2    Clark, D.3    Evans, S.4    Pickford, M.5    Newman, S.P.6
  • 26
    • 0024943092 scopus 로고
    • Seizures in haemodialysis patients treated with recombinant human erythropoietin
    • Edmunds M.E., Walls J., Tucker B., et al. Seizures in haemodialysis patients treated with recombinant human erythropoietin. Nephrol Dial Transplant 1989, 4:1065-1069.
    • (1989) Nephrol Dial Transplant , vol.4 , pp. 1065-1069
    • Edmunds, M.E.1    Walls, J.2    Tucker, B.3
  • 27
    • 0034997401 scopus 로고    scopus 로고
    • Development and characterization of novel erythropoiesis stimulating protein (NESP)
    • Egrie J.C., Browne J.K. Development and characterization of novel erythropoiesis stimulating protein (NESP). Br J Cancer 2001, 84:3-10.
    • (2001) Br J Cancer , vol.84 , pp. 3-10
    • Egrie, J.C.1    Browne, J.K.2
  • 29
    • 12244272391 scopus 로고    scopus 로고
    • Enhancement of therapeutic protein in vivo activities through glycoengineering
    • Elliott S., Lorenzini T., Asher S., Aoki K., Brankow D., Buck L. Enhancement of therapeutic protein in vivo activities through glycoengineering. Nat Biotechnol 2003, 21:414-421.
    • (2003) Nat Biotechnol , vol.21 , pp. 414-421
    • Elliott, S.1    Lorenzini, T.2    Asher, S.3    Aoki, K.4    Brankow, D.5    Buck, L.6
  • 30
    • 0000009635 scopus 로고
    • Humoral regulation of red cell production
    • Erslev A. Humoral regulation of red cell production. Blood 1953, 8:349-357.
    • (1953) Blood , vol.8 , pp. 349-357
    • Erslev, A.1
  • 31
    • 0023120533 scopus 로고
    • Correction of the anemia of end-stage renal disease with recombinant human erythropoietin. Results of a combined phase I and II clinical trial
    • Eschbach J.W., Egrie J.C., Downing M.R., Browne J.K., Adamson J.W. Correction of the anemia of end-stage renal disease with recombinant human erythropoietin. Results of a combined phase I and II clinical trial. N Engl J Med 1987, 316:73-78.
    • (1987) N Engl J Med , vol.316 , pp. 73-78
    • Eschbach, J.W.1    Egrie, J.C.2    Downing, M.R.3    Browne, J.K.4    Adamson, J.W.5
  • 32
    • 33748690610 scopus 로고    scopus 로고
    • Preclinical evaluation of Hematide, a novel erythropoiesis stimulating agent, for the treatment of anemia
    • Fan Q., Leuther K.K., Holmes C.P., Fong K.L., Zhang J., Velkovska S. Preclinical evaluation of Hematide, a novel erythropoiesis stimulating agent, for the treatment of anemia. Exp Hematol 2006, 34:1303-1311.
    • (2006) Exp Hematol , vol.34 , pp. 1303-1311
    • Fan, Q.1    Leuther, K.K.2    Holmes, C.P.3    Fong, K.L.4    Zhang, J.5    Velkovska, S.6
  • 33
    • 33750143699 scopus 로고    scopus 로고
    • Preclinical pharmacodynamics and pharmacokinetics of CERA (Continuous Erythropoietin Receptor Activator), an innovative erythropoietic agent for anemia management in patients with kidney disease
    • (Abstract SA-FC 123)
    • Fishbane S., Tare N., Pill J., Haselbeck A. Preclinical pharmacodynamics and pharmacokinetics of CERA (Continuous Erythropoietin Receptor Activator), an innovative erythropoietic agent for anemia management in patients with kidney disease. J Am Soc Nephrol 2003, 14:27A. (Abstract SA-FC 123).
    • (2003) J Am Soc Nephrol , vol.14
    • Fishbane, S.1    Tare, N.2    Pill, J.3    Haselbeck, A.4
  • 34
    • 85083922136 scopus 로고    scopus 로고
    • A phase I, single and fractionated, ascending dose study evaluating the safety, pharmacokinetics, pharmacodynamics, and immunogenicity of an erythropoietic mimetic antibody fusion protein, CTNO528 in healthy male subjects
    • Franson K.L., Burggraaf, Bouman-Trio E.A., et al. A phase I, single and fractionated, ascending dose study evaluating the safety, pharmacokinetics, pharmacodynamics, and immunogenicity of an erythropoietic mimetic antibody fusion protein, CTNO528 in healthy male subjects. Blood 2005, 106:146b.
    • (2005) Blood , vol.106
    • Franson, K.L.1    Burggraaf2    Bouman-Trio, E.A.3
  • 35
    • 33644867127 scopus 로고    scopus 로고
    • Cellular trafficking and degradation of erythropoietin and novel erythropoiesis stimulating protein (NESP)
    • Gross A.W., Lodish H.F. Cellular trafficking and degradation of erythropoietin and novel erythropoiesis stimulating protein (NESP). J Biol Chem 2006, 281:2024-2032.
    • (2006) J Biol Chem , vol.281 , pp. 2024-2032
    • Gross, A.W.1    Lodish, H.F.2
  • 36
    • 0026355305 scopus 로고
    • Comparative pharmacokinetics and pharmacodynamics of epoetin alfa and epoetin beta
    • Halstenson C.E., Macres M., Katz S.A., et al. Comparative pharmacokinetics and pharmacodynamics of epoetin alfa and epoetin beta. Clin Pharmacol Ther 1991, 50:702-712.
    • (1991) Clin Pharmacol Ther , vol.50 , pp. 702-712
    • Halstenson, C.E.1    Macres, M.2    Katz, S.A.3
  • 37
    • 0042363938 scopus 로고    scopus 로고
    • The discovery and characterization of CERA, an innovative agent for the treatment of anemia
    • (Abstract 857)
    • Haselbeck A., Bailon P., Pahlke W., et al. The discovery and characterization of CERA, an innovative agent for the treatment of anemia. Blood 2002, 100:227A. (Abstract 857).
    • (2002) Blood , vol.100
    • Haselbeck, A.1    Bailon, P.2    Pahlke, W.3
  • 38
    • 84882528288 scopus 로고    scopus 로고
    • the KRN 321 Study Group. (2005). Intravenous administration of KRN321 (darbepoetin alfa) once every 4 weeks improves and maintains haemoglobin concentrations in peritoneal dialysis patients. Paper presented at 42nd ERA-EDTA Congress, Istanbul, Turkey.
    • Hiramatsu, M., Kubota, J., Akizawa, T., Koshikawa, S., and the KRN 321 Study Group. (2005). Intravenous administration of KRN321 (darbepoetin alfa) once every 4 weeks improves and maintains haemoglobin concentrations in peritoneal dialysis patients. Paper presented at 42nd ERA-EDTA Congress, Istanbul, Turkey.
    • Hiramatsu, M.1    Kubota, J.2    Akizawa, T.3    Koshikawa, S.4
  • 39
    • 36049007201 scopus 로고    scopus 로고
    • Recombinant EPO production - points the nephrologist should know
    • Jelkmann W. Recombinant EPO production - points the nephrologist should know. Nephrol Dial Transplant 2007, 22:2749-2753.
    • (2007) Nephrol Dial Transplant , vol.22 , pp. 2749-2753
    • Jelkmann, W.1
  • 41
    • 0032572918 scopus 로고    scopus 로고
    • Subcutaneous compared with intravenous epoetin in patients receiving hemodialysis. Department of Veterans Affairs Cooperative Study Group on Erythropoietin in Hemodialysis patients
    • Kaufman J.S., Reda D.J., Fye C.L., et al. Subcutaneous compared with intravenous epoetin in patients receiving hemodialysis. Department of Veterans Affairs Cooperative Study Group on Erythropoietin in Hemodialysis patients. N Engl J Med 1998, 339:578-583.
    • (1998) N Engl J Med , vol.339 , pp. 578-583
    • Kaufman, J.S.1    Reda, D.J.2    Fye, C.L.3
  • 42
    • 0025928229 scopus 로고
    • Quality of life in end-stage renal disease patients during recombinant human erythropoietin therapy
    • Keown P.A. Quality of life in end-stage renal disease patients during recombinant human erythropoietin therapy. Contrib Nephrol 1991, 88:81-86.
    • (1991) Contrib Nephrol , vol.88 , pp. 81-86
    • Keown, P.A.1
  • 43
    • 36249017329 scopus 로고    scopus 로고
    • Efficacy of intravenous methoxy polyethylene-glycol epoetin beta administered every 2 weeks compared with epoetin administered 3 times weekly in patients treated by hemodialysis or peritoneal dialysis: a randomized trial
    • Klinger M., Arias M., Vargemezis V., et al. Efficacy of intravenous methoxy polyethylene-glycol epoetin beta administered every 2 weeks compared with epoetin administered 3 times weekly in patients treated by hemodialysis or peritoneal dialysis: a randomized trial. Am J Kidney Dis 2007, 50:989-1000.
    • (2007) Am J Kidney Dis , vol.50 , pp. 989-1000
    • Klinger, M.1    Arias, M.2    Vargemezis, V.3
  • 44
    • 33847386390 scopus 로고    scopus 로고
    • Epoetin delta, erythropoietin produced in a human cell line, in the management of anaemia in pre-dialysis chronic kidney disease patients
    • Kwan J.T., Pratt R.D. Epoetin delta, erythropoietin produced in a human cell line, in the management of anaemia in pre-dialysis chronic kidney disease patients. Curr Med Res Opin 2007, 23:307-311.
    • (2007) Curr Med Res Opin , vol.23 , pp. 307-311
    • Kwan, J.T.1    Pratt, R.D.2
  • 46
    • 28144448457 scopus 로고    scopus 로고
    • The prolonged half-lives of new erythropoietin derivatives via peptide addition
    • Lee D.E., Son W., Ha B.J., Oh M.S., Yoo O.J. The prolonged half-lives of new erythropoietin derivatives via peptide addition. Biochem Biophys Res Commun 2006, 339:380-385.
    • (2006) Biochem Biophys Res Commun , vol.339 , pp. 380-385
    • Lee, D.E.1    Son, W.2    Ha, B.J.3    Oh, M.S.4    Yoo, O.J.5
  • 47
    • 35348839061 scopus 로고    scopus 로고
    • Intravenous methoxy polyethylene glycol-epoetin beta for haemoglobin control in patients with chronic kidney disease who are on dialysis: a randomised non-inferiority trial (MAXIMA)
    • Levin N.W., Fishbane S., Canedo F.V., et al. Intravenous methoxy polyethylene glycol-epoetin beta for haemoglobin control in patients with chronic kidney disease who are on dialysis: a randomised non-inferiority trial (MAXIMA). Lancet 2007, 370:1415-1421.
    • (2007) Lancet , vol.370 , pp. 1415-1421
    • Levin, N.W.1    Fishbane, S.2    Canedo, F.V.3
  • 48
    • 0242611254 scopus 로고
    • Cloning and expression of the human erythropoietin gene
    • Lin F.K., Suggs S., Lin C.H. Cloning and expression of the human erythropoietin gene. Proc Natl Acad Sci USA 1985, 82:7580-7584.
    • (1985) Proc Natl Acad Sci USA , vol.82 , pp. 7580-7584
    • Lin, F.K.1    Suggs, S.2    Lin, C.H.3
  • 49
    • 18744363354 scopus 로고    scopus 로고
    • Darbepoetin alfa administered once monthly maintains hemoglobin concentrations in patients with chronic kidney disease
    • Ling B., Walczyk M., Agarwal A., Carroll W., Liu W., Brenner R. Darbepoetin alfa administered once monthly maintains hemoglobin concentrations in patients with chronic kidney disease. Clin Nephrol 2005, 63:327-334.
    • (2005) Clin Nephrol , vol.63 , pp. 327-334
    • Ling, B.1    Walczyk, M.2    Agarwal, A.3    Carroll, W.4    Liu, W.5    Brenner, R.6
  • 50
    • 0029798402 scopus 로고    scopus 로고
    • Functional mimicry of a protein hormone by a peptide agonist: the EPO receptor complex at 2.8 A
    • Livnah O., Stura E.A., Johnson D.L., Middleton S.A., Mulcahy L.S., Wrighton N.C. Functional mimicry of a protein hormone by a peptide agonist: the EPO receptor complex at 2.8 A. Science 1996, 273:464-471.
    • (1996) Science , vol.273 , pp. 464-471
    • Livnah, O.1    Stura, E.A.2    Johnson, D.L.3    Middleton, S.A.4    Mulcahy, L.S.5    Wrighton, N.C.6
  • 51
    • 0037317083 scopus 로고    scopus 로고
    • Treatment of anaemia in dialysis patients with unit dosing of darbepoetin alfa at a reduced dose frequency relative to recombinant human erythropoietin (rHuEpo)
    • Locatelli F., Canaud B., Giacardy F., Martin-Malo A., Baker N., Wilson J. Treatment of anaemia in dialysis patients with unit dosing of darbepoetin alfa at a reduced dose frequency relative to recombinant human erythropoietin (rHuEpo). Nephrol Dial Transplant 2003, 18:362-369.
    • (2003) Nephrol Dial Transplant , vol.18 , pp. 362-369
    • Locatelli, F.1    Canaud, B.2    Giacardy, F.3    Martin-Malo, A.4    Baker, N.5    Wilson, J.6
  • 52
    • 33748332090 scopus 로고    scopus 로고
    • CERA (Continuous Erythropoietin Receptor Activator) maintains hemoglobin levels in dialysis patients when administered subcutaneously up to once every 4 weeks
    • on behalf of the BA16286 study group, (Abstract SU-PO051)
    • Locatelli F., Villa G., Arias M., et al. CERA (Continuous Erythropoietin Receptor Activator) maintains hemoglobin levels in dialysis patients when administered subcutaneously up to once every 4 weeks. J Am Soc Nephrol 2004, 15:543A. on behalf of the BA16286 study group, (Abstract SU-PO051).
    • (2004) J Am Soc Nephrol , vol.15
    • Locatelli, F.1    Villa, G.2    Arias, M.3
  • 53
    • 84882469939 scopus 로고    scopus 로고
    • A phase 3 multicentre, randomised, double-blind, non-inferiority trial to evaluate the efficacy of Aranesp (darbepoetin alfa) once every 2 weeks (Q2W) vs Aranesp once weekly (QW) in patients on haemodialysis. Paper presented at 42nd ERA-EDTA Congress, Istanbul, Turkey.
    • Locatelli, F., Villa, G., Backs, W., and Pino, M.D. (2005). A phase 3 multicentre, randomised, double-blind, non-inferiority trial to evaluate the efficacy of Aranesp (darbepoetin alfa) once every 2 weeks (Q2W) vs Aranesp once weekly (QW) in patients on haemodialysis. Paper presented at 42nd ERA-EDTA Congress, Istanbul, Turkey.
    • (2005)
    • Locatelli, F.1    Villa, G.2    Backs, W.3    Pino, M.D.4
  • 54
    • 33644875091 scopus 로고    scopus 로고
    • C.E.R.A. (Continuous Erythropoietin Receptor Activator): a new erythropoiesis-stimulating agent for the treatment of anemia
    • Macdougall I.C. C.E.R.A. (Continuous Erythropoietin Receptor Activator): a new erythropoiesis-stimulating agent for the treatment of anemia. Curr Hematol Rep 2005, 4:436-440.
    • (2005) Curr Hematol Rep , vol.4 , pp. 436-440
    • Macdougall, I.C.1
  • 55
    • 0025139446 scopus 로고
    • Long-term cardiorespiratory effects of amelioration of renal anaemia by erythropoietin
    • Macdougall I.C., Lewis N.P., Saunders M.J., et al. Long-term cardiorespiratory effects of amelioration of renal anaemia by erythropoietin. Lancet 1990, 335:489-493.
    • (1990) Lancet , vol.335 , pp. 489-493
    • Macdougall, I.C.1    Lewis, N.P.2    Saunders, M.J.3
  • 57
    • 0032737391 scopus 로고    scopus 로고
    • Pharmacokinetics of novel erythropoiesis stimulating protein compared with epoetin alfa in dialysis patients
    • Macdougall I.C., Gray S.J., Elston O., et al. Pharmacokinetics of novel erythropoiesis stimulating protein compared with epoetin alfa in dialysis patients. J Am Soc Nephrol 1999, 10:2392-2395.
    • (1999) J Am Soc Nephrol , vol.10 , pp. 2392-2395
    • Macdougall, I.C.1    Gray, S.J.2    Elston, O.3
  • 58
    • 0037338670 scopus 로고    scopus 로고
    • Correction of anaemia with darbepoetin alfa in patients with chronic kidney disease receiving dialysis
    • Macdougall I.C., Matcham J., Gray S.J. Correction of anaemia with darbepoetin alfa in patients with chronic kidney disease receiving dialysis. Nephrol Dial Transplant 2003, 18:576-581.
    • (2003) Nephrol Dial Transplant , vol.18 , pp. 576-581
    • Macdougall, I.C.1    Matcham, J.2    Gray, S.J.3
  • 59
    • 4444235775 scopus 로고    scopus 로고
    • CERA (Continuous Erythropoietin Receptor Activator) for the treatment of renal anemia: an innovative agent with unique receptor binding characteristics and prolonged serum half-life
    • (Abstract SU-PO1063)
    • Macdougall I.C., Bailon P., Tare N., et al. CERA (Continuous Erythropoietin Receptor Activator) for the treatment of renal anemia: an innovative agent with unique receptor binding characteristics and prolonged serum half-life. J Am Soc Nephrol 2003, 14:769A. (Abstract SU-PO1063).
    • (2003) J Am Soc Nephrol , vol.14
    • Macdougall, I.C.1    Bailon, P.2    Tare, N.3
  • 60
    • 33750973533 scopus 로고    scopus 로고
    • Pharmacokinetics and pharmacodynamics of intravenous and subcutaneous continuous erythropoietin receptor activator (C.E.R.A.) in patients with chronic kidney disease
    • Macdougall I.C., Robson R., Opatrna S., et al. Pharmacokinetics and pharmacodynamics of intravenous and subcutaneous continuous erythropoietin receptor activator (C.E.R.A.) in patients with chronic kidney disease. Clin J Am Soc Nephrol 2006, 1:1211-1215.
    • (2006) Clin J Am Soc Nephrol , vol.1 , pp. 1211-1215
    • Macdougall, I.C.1    Robson, R.2    Opatrna, S.3
  • 61
    • 60149110184 scopus 로고    scopus 로고
    • Hematide, a synthetic peptide-based erythropoiesis stimulating agent, achieves correction of anemia and maintains Hb in patients with CKD not on dialysis
    • Abs F-FC079.
    • Macdougall, I.C., Tucker, B., Yaqoob, M. et al. (2006b). Hematide, a synthetic peptide-based erythropoiesis stimulating agent, achieves correction of anemia and maintains Hb in patients with CKD not on dialysis. Ann Meet Am Soc Nephrol 39, Abs F-FC079.
    • (2006) Ann Meet Am Soc Nephrol , vol.39
    • Macdougall, I.C.1    Tucker, B.2    Yaqoob, M.3
  • 63
    • 52449107076 scopus 로고    scopus 로고
    • Treatment of erythropoietin antibody-mediated pure red cell aplasia with a novel synthetic peptide-based erythropoietin receptor agonist.
    • Abs SU-FC061
    • Macdougall I.C., Casadevall N., Froissart M., et al. Treatment of erythropoietin antibody-mediated pure red cell aplasia with a novel synthetic peptide-based erythropoietin receptor agonist. Ann Meet Am Soc Nephrol 2007, 40. Abs SU-FC061.
    • (2007) Ann Meet Am Soc Nephrol , vol.40
    • Macdougall, I.C.1    Casadevall, N.2    Froissart, M.3
  • 64
    • 38749115086 scopus 로고    scopus 로고
    • Novel erythropoiesis-stimulating agents: A new era in anemia management
    • Macdougall I.C. Novel erythropoiesis-stimulating agents: A new era in anemia management. Clin J Am Soc Nephrol 2008, 3:200-207.
    • (2008) Clin J Am Soc Nephrol , vol.3 , pp. 200-207
    • Macdougall, I.C.1
  • 65
    • 42549141095 scopus 로고    scopus 로고
    • C.E.R.A. corrects anemia in patients with chronic kidney disease not on dialysis: results of a randomized clinical trial
    • Macdougall I.C., Walker R., Provenzano R., et al. C.E.R.A. corrects anemia in patients with chronic kidney disease not on dialysis: results of a randomized clinical trial. Clin J Am Soc Nephrol 2008, 3:337-347.
    • (2008) Clin J Am Soc Nephrol , vol.3 , pp. 337-347
    • Macdougall, I.C.1    Walker, R.2    Provenzano, R.3
  • 66
    • 0032810267 scopus 로고    scopus 로고
    • Distribution characteristics of entrapped recombinant human erythropoietin in liposomes and its intestinal absorption in rats
    • Maitani Y., Moriya H., Shimoda N., Takayama K., Nagai T. Distribution characteristics of entrapped recombinant human erythropoietin in liposomes and its intestinal absorption in rats. Int J Pharm 1999, 185:13-22.
    • (1999) Int J Pharm , vol.185 , pp. 13-22
    • Maitani, Y.1    Moriya, H.2    Shimoda, N.3    Takayama, K.4    Nagai, T.5
  • 67
    • 84882531931 scopus 로고    scopus 로고
    • Darbepoetin alfa (DA) every 2 weeks (Q2W) is effective in dialysis patients (pts) on high prior weekly (QW) doses of rHuEPO, a subanalysis of combined data from 8 prospective multicenter studies. Paper presented at ASN 38th Annual Renal Week Meeting, Philadelphia.
    • Mann, J., Kessler, M., Villa, G. et al. (2005). Darbepoetin alfa (DA) every 2 weeks (Q2W) is effective in dialysis patients (pts) on high prior weekly (QW) doses of rHuEPO, a subanalysis of combined data from 8 prospective multicenter studies. Paper presented at ASN 38th Annual Renal Week Meeting, Philadelphia.
    • (2005)
    • Mann, J.1    Kessler, M.2    Villa, G.3
  • 68
    • 33947241998 scopus 로고    scopus 로고
    • Darbepoetin alfa once every 2 weeks for treatment of anemia in dialysis patients: a combined analysis of eight multicenter trials
    • Mann J., Kessler M., Villa G., et al. Darbepoetin alfa once every 2 weeks for treatment of anemia in dialysis patients: a combined analysis of eight multicenter trials. Clin Nephrol 2007, 67:140-148.
    • (2007) Clin Nephrol , vol.67 , pp. 140-148
    • Mann, J.1    Kessler, M.2    Villa, G.3
  • 69
    • 36048947690 scopus 로고    scopus 로고
    • Epoetin delta in the management of renal anaemia: results of a 6-month study
    • on behalf of the Epoetin Delta 3001 Study Group
    • Martin K.J. Epoetin delta in the management of renal anaemia: results of a 6-month study. Nephrol Dial Transplant 2007, 22:3052-3054. on behalf of the Epoetin Delta 3001 Study Group.
    • (2007) Nephrol Dial Transplant , vol.22 , pp. 3052-3054
    • Martin, K.J.1
  • 70
    • 0023767527 scopus 로고
    • Working capacity is increased following recombinant human erythropoietin treatment
    • Mayer G., Thum J., Cada E.M., et al. Working capacity is increased following recombinant human erythropoietin treatment. Kidney Int 1988, 34:525-528.
    • (1988) Kidney Int , vol.34 , pp. 525-528
    • Mayer, G.1    Thum, J.2    Cada, E.M.3
  • 71
    • 0029125922 scopus 로고
    • Ultrasound-mediated transdermal protein delivery
    • Mitragotri S., Blankschtein D., Langer R. Ultrasound-mediated transdermal protein delivery. Science 1995, 269:850-853.
    • (1995) Science , vol.269 , pp. 850-853
    • Mitragotri, S.1    Blankschtein, D.2    Langer, R.3
  • 72
    • 0017755573 scopus 로고
    • Purification of human erythropoietin
    • Miyake T., Kung C.K., Goldwasser E. Purification of human erythropoietin. J Biol Chem 1977, 252:5558-5564.
    • (1977) J Biol Chem , vol.252 , pp. 5558-5564
    • Miyake, T.1    Kung, C.K.2    Goldwasser, E.3
  • 73
    • 34548046760 scopus 로고    scopus 로고
    • KDOQI clinical practice guideline and clinical practice recommendations for anemia in chronic kidney disease - 2007 update of hemoglobin target
    • National Kidney Foundation
    • National Kidney Foundation KDOQI clinical practice guideline and clinical practice recommendations for anemia in chronic kidney disease - 2007 update of hemoglobin target. Am J Kidney Dis 2007, 50:471-530.
    • (2007) Am J Kidney Dis , vol.50 , pp. 471-530
  • 74
    • 0036280663 scopus 로고    scopus 로고
    • Randomized, controlled trial of darbepoetin alfa for the treatment of anemia in hemodialysis patients
    • Nissenson A.R., Swan S.K., Lindberg J.S., et al. Randomized, controlled trial of darbepoetin alfa for the treatment of anemia in hemodialysis patients. Am J Kidney Dis 2002, 40:110-118.
    • (2002) Am J Kidney Dis , vol.40 , pp. 110-118
    • Nissenson, A.R.1    Swan, S.K.2    Lindberg, J.S.3
  • 75
    • 0002210665 scopus 로고    scopus 로고
    • National Kidney Foundation-Dialysis Outcomes Quality Initiative
    • NKF-DOQI clinical practice guidelines for the treatment of anemia of chronic renal failure
    • NKF-DOQI clinical practice guidelines for the treatment of anemia of chronic renal failure (1997). National Kidney Foundation-Dialysis Outcomes Quality Initiative. Am J Kidney Dis30 (4 Suppl 3): S192-240.
    • (1997) Am J Kidney Dis , vol.30 , Issue.4 SUPPL 3
  • 76
    • 84882481121 scopus 로고    scopus 로고
    • Pharmacokinetics (PK) of Aranesp (darbepoetin alfa) in patients with chronic kidney disease (CKD) (Abstract MP 165). Paper presented at 42nd ERA-EDTA Congress, Istanbul, Turkey.
    • Padhi, D., and Jang, G. (2005). Pharmacokinetics (PK) of Aranesp (darbepoetin alfa) in patients with chronic kidney disease (CKD) (Abstract MP 165). Paper presented at 42nd ERA-EDTA Congress, Istanbul, Turkey.
    • (2005)
    • Padhi, D.1    Jang, G.2
  • 77
    • 33646132045 scopus 로고    scopus 로고
    • An extended terminal half-life for darbepoetin alfa: results from a single-dose pharmacokinetic study in patients with chronic kidney disease not receiving dialysis
    • Padhi D., Ni L., Cooke B., Marino R., Jang G. An extended terminal half-life for darbepoetin alfa: results from a single-dose pharmacokinetic study in patients with chronic kidney disease not receiving dialysis. Clin Pharmacokinet 2006, 45:503-510.
    • (2006) Clin Pharmacokinet , vol.45 , pp. 503-510
    • Padhi, D.1    Ni, L.2    Cooke, B.3    Marino, R.4    Jang, G.5
  • 78
    • 23244463549 scopus 로고    scopus 로고
    • Comparison of two recombinant erythropoietin formulations in patients with anemia due to end-stage renal disease on hemodialysis: A parallel, randomized, double blind study
    • the Bioequivalence Study of Erythropoietin Group
    • Pérez-Oliva J.F., Casanova-González M., García-García I., et al. Comparison of two recombinant erythropoietin formulations in patients with anemia due to end-stage renal disease on hemodialysis: A parallel, randomized, double blind study. BMC Nephrology 2005, 6:1-11. the Bioequivalence Study of Erythropoietin Group.
    • (2005) BMC Nephrology , vol.6 , pp. 1-11
    • Pérez-Oliva, J.F.1    Casanova-González, M.2    García-García, I.3
  • 79
    • 33846669860 scopus 로고    scopus 로고
    • Mortality and target haemoglobin concentrations in anaemic patients with chronic kidney disease treated with erythropoietin: a meta-analysis
    • Phrommintikul A., Haas S.J., Elsik M., et al. Mortality and target haemoglobin concentrations in anaemic patients with chronic kidney disease treated with erythropoietin: a meta-analysis. Lancet 2007, 369:381-388.
    • (2007) Lancet , vol.369 , pp. 381-388
    • Phrommintikul, A.1    Haas, S.J.2    Elsik, M.3
  • 80
    • 42549146746 scopus 로고    scopus 로고
    • An optimized supravalent EPO mimetic peptide with unprecedented efficacy
    • Pötgens A., Haberl U., Rybka A., et al. An optimized supravalent EPO mimetic peptide with unprecedented efficacy. Ann Hematol 2006, 85:643.
    • (2006) Ann Hematol , vol.85 , pp. 643
    • Pötgens, A.1    Haberl, U.2    Rybka, A.3
  • 81
    • 34248356036 scopus 로고    scopus 로고
    • The continuous erythropoietin receptor activator (C.E.R.A.) corrects anemia at extended administration intervals in patients with chronic kidney disease not on dialysis: results of a phase II study
    • and BA 16528 Study Investigators
    • Provenzano R., Besarab A., Macdougall I.C., et al. The continuous erythropoietin receptor activator (C.E.R.A.) corrects anemia at extended administration intervals in patients with chronic kidney disease not on dialysis: results of a phase II study. Clin Nephrol 2007, 67:306-317. and BA 16528 Study Investigators.
    • (2007) Clin Nephrol , vol.67 , pp. 306-317
    • Provenzano, R.1    Besarab, A.2    Macdougall, I.C.3
  • 83
    • 20844450249 scopus 로고    scopus 로고
    • Erythropoietin receptors: their role beyond erythropoiesis
    • Rossert J., Eckardt K.-U. Erythropoietin receptors: their role beyond erythropoiesis. Nephrol Dial Transplant 2005, 20:1025-1028.
    • (2005) Nephrol Dial Transplant , vol.20 , pp. 1025-1028
    • Rossert, J.1    Eckardt, K.-U.2
  • 84
    • 84882560697 scopus 로고    scopus 로고
    • Hemoglobin responses following de novo darbepoetin alfa (ARANESP) vs epoetin alfa (PROCRIT) administration in anemic chronic kidney disease (CKD) patients. Paper presented at ASN 37th Renal Week Meeting, St Louis.
    • Sarac, E., Veres, Z., Tallam, S., Barton, D., and Gemmel, D. (2004). Hemoglobin responses following de novo darbepoetin alfa (ARANESP) vs epoetin alfa (PROCRIT) administration in anemic chronic kidney disease (CKD) patients. Paper presented at ASN 37th Renal Week Meeting, St Louis.
    • (2004)
    • Sarac, E.1    Veres, Z.2    Tallam, S.3    Barton, D.4    Gemmel, D.5
  • 85
    • 38749140300 scopus 로고    scopus 로고
    • The first biosimilar epoetin: but how similar is it?
    • Schellekens H. The first biosimilar epoetin: but how similar is it?. Clin J Am Soc Nephrol 2008, 3:174-178.
    • (2008) Clin J Am Soc Nephrol , vol.3 , pp. 174-178
    • Schellekens, H.1
  • 86
    • 0036197002 scopus 로고    scopus 로고
    • Epoetin omega for treatment of anemia in maintenance hemodialysis patients
    • Sikole A., Spasovski G., Zafirov D., Polenakovic M. Epoetin omega for treatment of anemia in maintenance hemodialysis patients. Clin Nephrol 2002, 57:237-245.
    • (2002) Clin Nephrol , vol.57 , pp. 237-245
    • Sikole, A.1    Spasovski, G.2    Zafirov, D.3    Polenakovic, M.4
  • 87
    • 33750983605 scopus 로고    scopus 로고
    • Correction of anemia with epoetin alfa in chronic kidney disease
    • Singh A.K., Szczech L., Tang K.L., et al. Correction of anemia with epoetin alfa in chronic kidney disease. N Engl J Med 2006, 335:2085-2098.
    • (2006) N Engl J Med , vol.335 , pp. 2085-2098
    • Singh, A.K.1    Szczech, L.2    Tang, K.L.3
  • 88
    • 0035895071 scopus 로고    scopus 로고
    • Sugar profiling proves that human serum erythropoietin differs from recombinant human erythropoietin
    • Skibeli V., Nissen-Lie G., Torjesen P. Sugar profiling proves that human serum erythropoietin differs from recombinant human erythropoietin. Blood 2001, 98:3626-3634.
    • (2001) Blood , vol.98 , pp. 3626-3634
    • Skibeli, V.1    Nissen-Lie, G.2    Torjesen, P.3
  • 89
    • 33845965338 scopus 로고    scopus 로고
    • Epoetin delta is effective for the management of anaemia associated with chronic kidney disease
    • Spinowitz B.S., Pratt R.D. Epoetin delta is effective for the management of anaemia associated with chronic kidney disease. Curr Med Res Opin 2006, 22:2507-2513.
    • (2006) Curr Med Res Opin , vol.22 , pp. 2507-2513
    • Spinowitz, B.S.1    Pratt, R.D.2
  • 90
    • 38349014009 scopus 로고    scopus 로고
    • C.E.R.A. maintains stable control of hemoglobin in patients with chronic kidney disease on dialysis when administered once every two weeks
    • Spinowitz B., Coyne D.W., Lok C.E., et al. C.E.R.A. maintains stable control of hemoglobin in patients with chronic kidney disease on dialysis when administered once every two weeks. Am J Nephrol 2008, 28:280-289.
    • (2008) Am J Nephrol , vol.28 , pp. 280-289
    • Spinowitz, B.1    Coyne, D.W.2    Lok, C.E.3
  • 91
    • 33748679131 scopus 로고    scopus 로고
    • Evaluation of the safety and pharmacodynamics of Hematide, a novel erythropoietic agent, in a phase 1, double-blind placebo-controlled, dose-escalation study in healthy volunteers
    • Stead R.B., Lambert J., Wessels D., Iwashita J.S., Leuther K.K., Woodburn K.W. Evaluation of the safety and pharmacodynamics of Hematide, a novel erythropoietic agent, in a phase 1, double-blind placebo-controlled, dose-escalation study in healthy volunteers. Blood 2006, 108:1830-1834.
    • (2006) Blood , vol.108 , pp. 1830-1834
    • Stead, R.B.1    Lambert, J.2    Wessels, D.3    Iwashita, J.S.4    Leuther, K.K.5    Woodburn, K.W.6
  • 92
    • 34548207889 scopus 로고    scopus 로고
    • Once-monthly subcutaneous C.E.R.A. maintains stable hemoglobin control in patients with chronic kidney disease on dialysis and converted directly from epoetin one to three times weekly
    • Sulowicz W., Locatelli F., Ryckelynck J.-P., et al. Once-monthly subcutaneous C.E.R.A. maintains stable hemoglobin control in patients with chronic kidney disease on dialysis and converted directly from epoetin one to three times weekly. Clin J Am Soc Nephrol 2007, 2:637-646.
    • (2007) Clin J Am Soc Nephrol , vol.2 , pp. 637-646
    • Sulowicz, W.1    Locatelli, F.2    Ryckelynck, J.-P.3
  • 93
    • 0037255238 scopus 로고    scopus 로고
    • Treatment of anemia with darbepoetin alfa administered de novo once every other week in chronic kidney disease
    • Suranyi M.G., Lindberg J.S., Navarro J., Elias C., Brenner R.M., Walker R. Treatment of anemia with darbepoetin alfa administered de novo once every other week in chronic kidney disease. Am J Nephrol 2003, 23:106-111.
    • (2003) Am J Nephrol , vol.23 , pp. 106-111
    • Suranyi, M.G.1    Lindberg, J.S.2    Navarro, J.3    Elias, C.4    Brenner, R.M.5    Walker, R.6
  • 94
    • 0033609857 scopus 로고    scopus 로고
    • An erythropoietin fusion protein comprised of identical repeating domains exhibits enhanced biological properties
    • Sytkowski A.J., Lunn E.D., Risinger M.A., Davis K.L. An erythropoietin fusion protein comprised of identical repeating domains exhibits enhanced biological properties. J Biol Chem 1999, 274:24773-24778.
    • (1999) J Biol Chem , vol.274 , pp. 24773-24778
    • Sytkowski, A.J.1    Lunn, E.D.2    Risinger, M.A.3    Davis, K.L.4
  • 96
    • 0025878215 scopus 로고
    • Hemodynamic changes in hemodialyzed patients during treatment with recombinant human erythropoietin
    • Teruel J.L., Pascual J., Jiménez M., et al. Hemodynamic changes in hemodialyzed patients during treatment with recombinant human erythropoietin. Nephron 1991, 58:135-137.
    • (1991) Nephron , vol.58 , pp. 135-137
    • Teruel, J.L.1    Pascual, J.2    Jiménez, M.3
  • 97
    • 84882511076 scopus 로고    scopus 로고
    • The Court Service - Court of Appeal - Civil Judgement. (2002). In TKT's technology, those cells were designated as R223 cells. Neutral Citation Number: EWCA Civ. 1096.
    • The Court Service - Court of Appeal - Civil Judgement. (2002). In TKT's technology, those cells were designated as R223 cells. Neutral Citation Number: EWCA Civ. 1096. http://www.hmcourtsservice.gov.uk/judgmentsfiles/j1329/Kirin_v_Hoechst.h tm.
  • 98
    • 4644357756 scopus 로고    scopus 로고
    • Darbepoetin alfa effectively treats anemia in patients with chronic kidney disease with de novo every-other-week administration
    • Toto R.D., Pichette V., Navarro J., et al. Darbepoetin alfa effectively treats anemia in patients with chronic kidney disease with de novo every-other-week administration. Am J Nephrol 2004, 24:453-460.
    • (2004) Am J Nephrol , vol.24 , pp. 453-460
    • Toto, R.D.1    Pichette, V.2    Navarro, J.3
  • 99
    • 84882509994 scopus 로고    scopus 로고
    • The pharmacokinetics of KRN321 (darbepoetin alfa) after subcutaneous (SC) administration: a comparison between peritoneal dialysis and predialysis chronic renal failure (CRF) patients in Japan
    • the KRN321 Study Group., Paper presented at 41st ERA-EDTA Congress, Lisbon, Portugal.
    • Tsubakihara, Y., Hiramatsu, M., Iino, Y., Akizawa, T., Koshikawa, S., and the KRN321 Study Group. (2004). The pharmacokinetics of KRN321 (darbepoetin alfa) after subcutaneous (SC) administration: a comparison between peritoneal dialysis and predialysis chronic renal failure (CRF) patients in Japan. Paper presented at 41st ERA-EDTA Congress, Lisbon, Portugal.
    • (2004)
    • Tsubakihara, Y.1    Hiramatsu, M.2    Iino, Y.3    Akizawa, T.4    Koshikawa, S.5
  • 100
    • 84882468609 scopus 로고    scopus 로고
    • on behalf of the Aranesp registry group, Feasibility to increase the dosing interval of darbepoetin alfa (Aranesp®) to once monthly (QM) in patients with chronic renal insufficiency (CRI)
    • Paper presented at 42nd ERA-EDTA Congress, Istanbul, Turkey.
    • van Buren, M., van Manen, J.G., Bakker-de Bruin, Y., Boeschoten, E.W. on behalf of the Aranesp registry group (2005). Feasibility to increase the dosing interval of darbepoetin alfa (Aranesp®) to once monthly (QM) in patients with chronic renal insufficiency (CRI). Paper presented at 42nd ERA-EDTA Congress, Istanbul, Turkey.
    • (2005)
    • van Buren, M.1    van Manen, J.G.2    Bakker-de Bruin, Y.3    Boeschoten, E.W.4
  • 101
    • 0036436322 scopus 로고    scopus 로고
    • Randomized trial of darbepoetin alfa for treatment of renal anemia at a reduced dose frequency compared with rHuEPO in dialysis patients
    • Vanrenterghem Y., Barany P., Mann J.F., et al. Randomized trial of darbepoetin alfa for treatment of renal anemia at a reduced dose frequency compared with rHuEPO in dialysis patients. Kidney Int 2002, 62:2167-2175.
    • (2002) Kidney Int , vol.62 , pp. 2167-2175
    • Vanrenterghem, Y.1    Barany, P.2    Mann, J.F.3
  • 102
    • 33344470867 scopus 로고    scopus 로고
    • Pharmacokinetic and pharmacodynamic studies following oral administration of erythropoietin mucoadhesive tablets to beagle dogs
    • Venkatesan N., Yoshimitsu J., Ohashi Y., et al. Pharmacokinetic and pharmacodynamic studies following oral administration of erythropoietin mucoadhesive tablets to beagle dogs. Int J Pharm 2006, 310:46-52.
    • (2006) Int J Pharm , vol.310 , pp. 46-52
    • Venkatesan, N.1    Yoshimitsu, J.2    Ohashi, Y.3
  • 103
    • 21044443734 scopus 로고    scopus 로고
    • Improvement of Fc-erythropoietin structure and pharmacokinetics by modification at a disulfide bond
    • Way J.C., Lauder S., Brunkhorst B., Kong S.M., Qi A., Webster G. Improvement of Fc-erythropoietin structure and pharmacokinetics by modification at a disulfide bond. Protein Eng Des Sel 2005, 18:111-118.
    • (2005) Protein Eng Des Sel , vol.18 , pp. 111-118
    • Way, J.C.1    Lauder, S.2    Brunkhorst, B.3    Kong, S.M.4    Qi, A.5    Webster, G.6
  • 104
    • 0022980521 scopus 로고
    • Effect of human erythropoietin derived from recombinant DNA on the anaemia of patients maintained by chronic haemodialysis.
    • Winearls C.G., Oliver D.O., Pippard M.J., Reid C., Downing M.R., Cotes P.M. Effect of human erythropoietin derived from recombinant DNA on the anaemia of patients maintained by chronic haemodialysis. Lancet 1986, ii:1175-1178.
    • (1986) Lancet , vol.2 , pp. 1175-1178
    • Winearls, C.G.1    Oliver, D.O.2    Pippard, M.J.3    Reid, C.4    Downing, M.R.5    Cotes, P.M.6
  • 105
    • 60149109022 scopus 로고    scopus 로고
    • Renal excretion is the primary route of elimination for the erythropoiesis stimulating agent Hematide as assessed by quantitative whole-body autoradioluminography in Sprague Dawley rats
    • Abs SaP333.
    • Woodburn, K., Leuther, K., Holmes, C. et al. (2007a). Renal excretion is the primary route of elimination for the erythropoiesis stimulating agent Hematide as assessed by quantitative whole-body autoradioluminography in Sprague Dawley rats. Nephrol Dial Transplant22: (Suppl 6): Abs SaP333.
    • (2007) Nephrol Dial Transplant , vol.22 , Issue.SUPPL 6
    • Woodburn, K.1    Leuther, K.2    Holmes, C.3
  • 106
    • 34447636387 scopus 로고    scopus 로고
    • Hematide is immunologically distinct from erythropoietin and corrects anemia induced by antierythropoietin antibodies in a rat pure red cell aplasia model
    • Woodburn K.W., Fan Q., Winslow S., et al. Hematide is immunologically distinct from erythropoietin and corrects anemia induced by antierythropoietin antibodies in a rat pure red cell aplasia model. Exp Hematol 2007, 35:1201-1208.
    • (2007) Exp Hematol , vol.35 , pp. 1201-1208
    • Woodburn, K.W.1    Fan, Q.2    Winslow, S.3
  • 108
    • 0026565275 scopus 로고
    • Design of yeast-secreted albumin derivatives for human therapy: biological and antiviral properties of a serum albumin-CD4 genetic conjugate
    • Yeh P., Landais D., Lemaitre M., et al. Design of yeast-secreted albumin derivatives for human therapy: biological and antiviral properties of a serum albumin-CD4 genetic conjugate. Proc Natl Acad Sci USA 1992, 89:1904-1908.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 1904-1908
    • Yeh, P.1    Landais, D.2    Lemaitre, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.