Nuclear Receptors in Drosophila Melanogaster

Handbook of Cell Signaling, Second Edition

Volumn 3, Issue , 2009, Pages 2027-2037

  Henrich, Vincent C ^a   Beatty, Joshua M ^a  

^a UNIVERSITY OF NORTH CAROLINA AT GREENSBORO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 84882467875     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1016/B978-0-12-374145-5.00248-5     Document Type: Chapter

References (77)

1. X Hu, L Cherbas and P Cherbas (2003) Transcription activation by the ecdysone receptor (EcR/USP): identification of activation functions. Mol Endocrinol 17 716-731.
2. MR Koelle, WS Talbot, WA Segraves, MT Bender, P Cherbas and DS Hogness (1991) The Drosophila EcR gene encodes an ecdysone receptor, a new member of the steroid receptor superfamily. Cell 67 59-77.
3. J Reinking, MM Lam, K Pardee, HM Sampson, S Liu, P Yang, S Williams, W White, G Lajoie, A Edwards and HM Krause (2005) The Drosophila nuclear receptor e75 contains heme and is gas responsive. Cell 122 195-207.
4. AE Oro, ES Ong, JS Margolis, JW Posakony, M McKeown and RM Evans (1988) The Drosophila gene knirps-related is a member of the steroid-receptor gene superfamily. Nature 336 493-496.
5. U Nauber, MJ Pankratz, A Kienlin, E Seifert, U Klemm and H Jäckle (1988) Abdominal segmentation of the Drosophila embryo requires a hormone receptor-like protein encoded by the gap gene knirps. Nature 336 489-492.
6. G Richards, JL Da Lage, F Huet and C Ruiz (1999) The acquisition of competence to respond to ecdysone in Drosophila is transcript specific. Mech Dev 82 131-139.
7. K King-Jones and CS Thummel (2005) Developmental biology. Less steroids make bigger flies. Science 310 630-631.
8. X Bellés, D Martín and MD Piulachs (2005) The mevalonate pathway and the synthesis of juvenile hormone in insects. Annu Rev Entomol 50 181-199.
9. EB Dubrovsky, VA Dubrovskaya and EM Berger (2004) Hormonal regulation and functional role of Drosophila E75A orphan nuclear receptor in the juvenile hormone signaling pathway. Dev Biol 268 258-270.
10. RB Beckstead, G Lam and CS Thummel (2007) Specific transcriptional responses to juvenile hormone and ecdysone in Drosophila. Insect Biochem Mol Biol 37 570-578.
11. AE Oro, M McKeown and RM Evans (1990) Relationship between the product of the Drosophila ultraspiracle locus and the vertebrate retinoid X receptor. Nature 347 298-301.
12. HE Thomas, HG Stunnenberg and AF Stewart (1993) Heterodimerization of the Drosophila ecdysone receptor with retinoid X receptor and ultraspiracle. Nature 362 471-475.
13. TP Yao, BM Forman, Z Jiang, L Cherbas, JD Chen, M McKeown, P Cherbas and RM Evans (1993) Functional ecdysone receptor is the product of EcR and Ultraspiracle genes. Nature 366 476-479.
14. WS Talbot, EA Swyryd and DS Hogness (1993) Drosophila tissues with different metamorphic responses to ecdysone express different ecdysone receptor isoforms. Cell 73 1323-1337.
15. CS Thummel (2002) Ecdysone-regulated puff genes 2000. Insect Biochem Mol Biol 32 113-120.
16. F Huet, C Ruiz and G Richards (1993) Puffs and PCR: the in vivo dynamics of early gene expression during ecdysone responses in Drosophila. Development 118 613-627.
17. VC Henrich (2005) The ecdysteroid receptor. Comprehensive insect physiology, biochemistry, and molecular biology series vol. 3 Oxford, UK: Elsevier Press 243-286.
18. BF Costantino, DK Bricker, K Alexandre, K Shen, JR Merriam, C Antoniewski, JL Callender, VC Henrich, A Presente and AJ Andres (2008) A novel ecdysone receptor mediates steroid-regulated developmental events during the mid-third instar of Drosophila. PLoS Genet 4 e1,000,102.
19. M Grebe, S Przibilla, VC Henrich and M Spindler-Barth (2003) Characterization of the ligand-binding domain of the ecdysteroid receptor from Drosophila melanogaster. Biol Chem 384 105-116.
20. Y Sun, S An, VC Henrich, X Sun and Q Song (2007) Proteomic identification of PKC-mediated expression of 20E-induced protein in Drosophila melanogaster. J Proteome Res 6 4478-4488.
21. X Sun and Q Song (2006) PKC-mediated USP phosphorylation is required for 20E-induced gene expression in the salivary glands of Drosophila melanogaster. Arch Insect Biochem Physiol 62 116-127.
22. FD Karim and CS Thummel (1991) Ecdysone coordinates the timing and amounts of E74A and E74B transcription in Drosophila. Genes Dev 5 1067-1079.
23. MD Pak and LI Gilbert (1984) A developmental analysis of ecdysteroids during the metamorphosis of Drosophila melanogaster. J Liq Chromatogr 20 2591-2597.
24. G Sommé-Martin, J Colardeau, P Beydon, C Blais, JA Lepesant and R Lafont (1990) P1 gene expression in Drosophila larval fat body: induction by various ecdysteroids. Arch Insect Biochem Physiol 15 43-56.
25. VC Henrich, MD Pak and LI Gilbert (1987) Neural factors that stimulate ecdysteroid synthesis by the larval ring gland of Drosophila melanogaster. J Comp Physiol 157 543-549.
26. KD Baker, JT Warren, CS Thummel, LI Gilbert and DJ Mangelsdorf (2000) Transcriptional activation of the Drosophila ecdysone receptor by insect and plant ecdysteroids. Insect Biochem Mol Biol 30 1037-1043.
27. KD Baker, LM Shewchuk, T Kozlova, M Makishima, A Hassell, B Wisely, JA Caravella, MH Lambert, JL Reinking, H Krause, CS Thummel, TM Willson and DJ Mangelsdorf (2003) The Drosophila orphan nuclear receptor DHR38 mediates an atypical ecdysteroid signaling pathway. Cell 113 731-742.
28. MM Davis, P Yang, L Chen, SL O’Keefe and RB Hodgetts (2007) The orphan nuclear receptor DHR38 influences transcription of the DOPA decarboxylase gene in epidermal and neural tissues of Drosophila melanogaster. Genome 50 1049-1060.
29. P White, H Aberle and JP Vincent (1998) Signaling and adhesion activities of mammalian beta-catenin and plakoglobin in Drosophila. J Cell Biol 140 183-195.
30. CY Lee, DP Wendel, P Reid, G Lam, CS Thummel and EH Baehrecke (2000) E93 directs steroid-triggered programmed cell death in Drosophila. Mol Cell 6 433-443.
31. CY Lee, CR Simon, CT Woodard and EH Baehrecke (2002) Genetic mechanism for the stage- and tissue-specific regulation of steroid triggered programmed cell death in Drosophila. Dev Biol 252 138-148.
32. J Broadus, JR McCabe, B Endrizzi, CS Thummel and CT Woodard (1999) The Drosophila beta FTZ-F1 orphan nuclear receptor provides competence for stage-specific responses to the steroid hormone ecdysone. Mol Cell 3 143-149.
33. J Zhu, L Chen, G Sun and AS Raikhel (2006) The competence factor beta Ftz-F1 potentiates ecdysone receptor activity via recruiting a p160/SRC coactivator. Mol Cell Biol 9402-9412.
34. E de Rosny, A de Groot, C Jullian-Binard, J Gaillard, F Borel, E Pebay-Peyroula, JC Fontecilla-Camps and HM Jouve (2006) Drosophila nuclear receptor E75 is a thiolate hemoprotein. Biochemistry 45 9727-9734.
35. CS Thummel (2005) Powered by gas–a ligand for a fruit fly nuclear receptor. Cell 122 151-153.
36. M Bialecki, A Shilton, C Fichtenberg, WA Segraves and CS Thummel (2002) Loss of the ecdysteroid-inducible E75A orphan nuclear receptor uncouples molting from metamorphosis in Drosophila. Dev Cell 3 209-220.
37. K King-Jones, JP Charles, G Lam and CS Thummel (2005) The ecdysone-induced DHR4 orphan nuclear receptor coordinates growth and maturation in Drosophila. Cell 121 773-784.
38. KD Baker, RB Beckstead, DJ Mangelsdorf and CS Thummel (2007) Functional interactions between the Moses corepressor and DHR78 nuclear receptor regulate growth in Drosophila. Genes Dev 21 450-464.
39. K King-Jones, MA Horner, G Lam and CS Thummel (2006) The DHR96 nuclear receptor regulates xenobiotic responses in Drosophila. Cell Metab 4 37-48.
40. N Ghbeish, CC Tsai, M Schubiger, JY Zhou, RM Evans and M McKeown (2001) The dual role of ultraspiracle, the Drosophila retinoid X receptor, in the ecdysone response. Proc Natl Acad Sci USA 98 3867-3872.
41. IM Billas, T Iwema, JM Garnier, A Mitschler, N Rochel and D Moras (2003) Structural adaptability in the ligand-binding pocket of the ecdysone hormone receptor. Nature 426 91-96.
42. VC Henrich, JM Beatty, H Ruff, J Callender, M Grebe and M Spindler-Barth (2009) The multidimensional partnership of EcR and USP. G Smagghe (Ed.) Ecdysones, structures and functions Dordrecht: Springer-Verlag 361-375.
43. M Bender, FB Imam, WS Talbot, B Ganetzky and DS Hogness (1997) Drosophila ecdysone receptor mutations reveal functional differences among receptor isoforms. Cell 91 777-788.
44. M Schubiger, C Carré, C Antoniewski and JW Truman (2005) Ligand-dependent de-repression via EcR/USP acts as a gate to coordinate the differentiation of sensory neurons in the Drosophila wing. Development 132 5239-5248.
45. AC Zelhof, TP Yao, JD Chen, RM Evans and M McKeown (1995) Seven-up inhibits ultraspiracle-based signaling pathways in vitro and in vivo. Mol Cell Biol 15 6736-6745.
46. J Beatty, T Fauth, JL Callender, M Spindler-Barth and VC Henrich (2006) Analysis of transcriptional activity mediated by Drosophila melanogaster ecdysone receptor isoforms in a heterologous cell culture system. Insect Mol Biol 15 785-795.
47. L Cherbas, X Hu, I Zhimulev, E Belyaeva and P Cherbas (2003) EcR isoforms in Drosophila: testing tissue-specific requirements by targeted blockade and rescue. Development 130 271-284.
48. A Azotei and M Spindler-Barth (2009) DNA affects ligand binding of the ecdysone receptor of Drosophila melanogaster. Mol Cell Endocrinol 303 91-99.
49. C Nieva, T Gwòzdz, J Dutko-Gwózdz, J Wiedenmann, M Spindler-Barth, E Wieczorek, J Dobrucki, D Dus, V Henrich, A Ozyhar and KD Spindler (2005) Ultraspiracle promotes the nuclear localization of ecdysteroid receptor in mammalian cells. Biol Chem 386 463-470.
50. C Nieva, M Spindler-Barth, A Azoitei and KD Spindler (2007) Influence of hormone on intracellular localization of the Drosophila melanogaster ecdysteroid receptor (EcR). Cell Signal 19 2582-2587.
51. G Jones, M Wozniak, Y Chu, S Dhar and D Jones (2001) Juvenile hormone III-dependent conformational changes of the nuclear receptor ultraspiracle. Insect Biochem Mol Biol 32 33-49.
52. G Jones, D Jones, P Teal, A Sapa and M Wozniak (2006) The retinoid-X receptor ortholog, ultraspiracle, binds with nanomolar affinity to an endogenous morphogenetic ligand. FEBS J 273 4983-4996.
53. MA Harmon, MF Boehm, RA Heyman and DJ Mangelsdorf (1995) Activation of mammalian retinoid X receptors by the insect growth regulator methoprene. Proc Natl Acad Sci USA 92 6157-6160.
54. G Riddihough and HR Pelham (1987) An ecdysone response element in the Drosophila hsp27 promoter. EMBO J 6 3729-3734.
55. VC Henrich, E Burns, DP Yelverton, E Christensen and C Weinberger (2003) Juvenile hormone potentiates ecdysone receptor-dependent transcription in a mammalian cell culture system. Insect Biochem Mol Biol 33 1239-1247.
56. F Fang, Y Xu, D Jones and G Jones (2005) Interactions of ultraspiracle with ecdysone receptor in the transduction of ecdysone- and juvenile hormone-signaling. FEBS J 272 1577-1589.
57. M Ashok, C Turner and TG Wilson (1998) Insect juvenile hormone resistance gene homology with the bHLH-PAS family of transcriptional regulators. Proc Natl Acad Sci USA 95 2761-2766.
58. Y Li, Z Zhang, GE Robinson and SR Palli (2007) Identification and characterization of a juvenile hormone response element and its binding proteins. J Biol Chem 282 37,605-37,617.
59. B Konopova and M Jindra (2007) Juvenile hormone resistance gene Methoprene-tolerant controls entry into metamorphosis in the beetle Tribolium castaneum. Proc Natl Acad Sci U S A 104 10,488-10,493.
60. E Morán and G Jiménez (2006) The tailless nuclear receptor acts as a dedicated repressor in the early Drosophila embryo. Mol Cell Biol 26 3446-3454.
61. DE Clyde, MS Corado, X Wu, A Paré, D Papatsenko and S Small (2003) A self-organizing system of repressor gradients establishes segmental complexity in Drosophila. Nature 426 849-853.
62. K Lunde, B Biehs, U Nauber and E Bier (1998) The knirps and knirps-related genes organize development of the second wing vein in Drosophila. Development 125 4145-4154.
63. M Mlodzik, Y Hiromi, U Weber, CS Goodman and GM Rubin (1990) The Drosophila seven-up gene, a member of the steroid receptor gene superfamily, controls photoreceptor cell fates. Cell 60 211-224.
64. AC Miller, H Seymour, C King and TG Herman (2008) Loss of seven-up from Drosophila R1/R6 photoreceptors reveals a stochastic fate choice that is normally biased by Notch. Development 135 707-715.
65. AK Allen and AC Spradling (2008) The Sf1-related nuclear hormone receptor Hr39 regulates Drosophila female reproductive tract development and function. Development 135 311-321.
66. GE Carney and M Bender (2000) The Drosophila ecdysone receptor (EcR) gene is required maternally for normal oogenesis. Genetics 154 1203-1211.
67. N Perrimon, L Engstrom and AP Mahowald (1985) Developmental genetics of the 2C-D region of the Drosophila X chromosome. Genetics 111 23-41.
68. J Terashima and M Bownes (2006) E75A and E75B have opposite effects on the apoptosis/development choice of the Drosophila egg chamber. Cell Death Differ 13 454-464.
69. L Palanker, AS Necakov, HM Sampson, R Ni, C Hu, CS Thummel and HM Krause (2006) Dynamic regulation of Drosophila nuclear receptor activity in vivo. Development 133 3549-3562.
70. P Badenhorst, H Xiao, L Cherbas, SY Kwon, M Voas, I Rebay, P Cherbas and C Wu (2005) The Drosophila nucleosome remodeling factor NURF is required for Ecdysteroid signaling and metamorphosis. Genes Dev 19 2540-2545.
71. CJ Schwartz, HM Sampson, D Hlousek, A Percival-Smith, JW Copeland, AJ Simmonds and HM Krause (2001) FTZ-Factor1 and Fushi tarazu interact via conserved nuclear receptor and coactivator motifs. EMBO J 20 510-519.
72. T Suzuki, H Kawasaki, RT Yu, H Ueda and K Umesono (2001) Segmentation gene product Fushi tarazu is an LXXLL motif-dependent coactivator for orphan receptor FTZ-F1. Proc Natl Acad Sci USA 98 12,403-12,408.
73. GE Carney, AA Wade, R Sapra, ES Goldstein and M Bender (1997) DHR3, an ecdysone-inducible early–late gene encoding a Drosophila nuclear receptor, is required for embryogenesis. Proc Natl Acad Sci USA 94 12,024-12,029.
74. N Bruey-Sedano, J Alabouvette, M Lestradet, L Hong, A Girard, E Gervasio, B Quennedey and JP Charles (2005) The Drosophila ACP65A cuticle gene: deletion scanning analysis of cis-regulatory sequences and regulation by DHR38. Genesis 43 17-27.
75. L Wang, H Rajan, JL Pitman, M McKeown and CC Tsai (2006) Histone deacetylase-associating Atrophin proteins are nuclear receptor corepressors. Genes Dev 20 525-530.
76. P Yang, HM Sampson and HM Krause (2006) A modified tandem affinity purification strategy identifies cofactors of the Drosophila nuclear receptor dHNF4. Proteomics 6 927-935.
77. P Struffi and DN Arnosti (2005) Functional interaction between the Drosophila knirps short range transcriptional repressor and RPD3 histone deacetylase. J Biol Chem 280 40,757-40,765.