Juvenile hormone potentiates ecdysone receptor-dependent transcription in a mammalian cell culture system

Insect Biochemistry and Molecular Biology

Volumn 33, Issue 12, 2003, Pages 1239-1247

  Henrich, Vincent C ^a   Burns, Edina ^b   Yelverton, David P ^a   Christensen, Erin ^a   Weinberger, Cary ^b  

^a UNIVERSITY OF NORTH CAROLINA AT GREENSBORO   (United States)

^b NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

Author keywords

Ecdysteroid; FXR; Juvenile hormone; Nuclear receptor; RXR

Indexed keywords

CRICETINAE; CRICETULUS GRISEUS; INSECTA; MAMMALIA;

EID: 0344153323     PISSN: 09651748     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ibmb.2003.08.002     Document Type: Article

References (53)

1. Ashok, M., Turner, C., Wilson, T.G., 1998. Insect juvenile hormone resistance gene homology with the bHLH-PAS family of transcriptional regulators. Proc. Natl. Acad. Sci. USA 95, 2761-2766.
2. Baker, K.D., Warren, J.T., Thummel, C.S., Gilbert, L.I., Mangelsdorf, D.J., 2000. Transcriptional activation of the Drosophila ecdysone receptor by insect and plant ecdysteroids. Insect Biochem. Mol. Biol. 30, 1037-1043.
3. Bender, M., Imam, F.B., Talbot, W.S., Ganetzky, B., Hogness, D.S., 1997. Drosophila ecdysone receptor mutations reveal functional differences among receptor isoforms. Genetics 91, 777-788.
4. Cherbas, L., Koehler, M.M.D., Cherbas, P., 1989. Effects of juvenile hormone on the ecdysone response in Drosophila Kc cells. Dev. Genet. 10, 177-188.
5. Cherbas, L., Hu, X., Zhimulev, I., Belyaeva, E., Cherbas, P., 2003. EcR isoforms in Drosophila: testing tissue-specific requirements by targeted blockade and rescue. Development 130, 271-284.
6. Chiang, J.Y., Kimmel, R., Weinberger, C., Stroup, D., 2000. Farnesoid X receptor responds to bile acids and represses cholesterol 7 α-hydroxylase gene (CYP7A1) transcription. J. Biol. Chem. 275, 10918-10924.
7. Chihara, C.J., Fristrom, J.W., 1973. Effects and interactions of juvenile hormone and b-ecdysone on Drosophila imaginal discs cultured in vitro. Dev. Biol. 35, 36-46.
8. Christopherson, K.S., Mark, M.R., Bajaj, V., Godowski, P.J., 1992. Ecdysteroid-dependent regulation of genes in mammalian cells by a Drosophila ecdysone receptor and chimeric transactivators. Proc. Natl. Acad. Sci. USA 89, 6314-6318.
9. Dai, J.D., Gilbert, L.I., 1991. Metamorphosis of the corpus allatum and degeneration of the prothoracic glands during the larval-pupal-adult transformation of Drosophila melanogaster: a cytophysiological analysis of the ring gland. Dev. Biol. 144, 309-326.
10. Dubrovsky, E., Dubrovskaya, V.A., Berger, E.M., 2002. Juvenile hormone signaling during oogenesis in Drosophila melanogaster. Insect Biochem. Mol. Biol. 32, 1555-1565.
11. Farkas, R., Knopp, J., 1997. Ecdysone modulated response of Drosophila malate dehydrogenase to juvenile hormone. Arch. Insect Biochem. Physiol. 35, 71-83.
12. Forman, B.M., Goode, E., Chen, J., Oro, A.E., Bradley, D.J., Perlmann, T., Noonan, D.J., Burka, L.T., McMorris, T., Lamph, W.W., Evans, R.M., Weinberger, C., 1995. Identification of a nuclear receptor that is activated by farnesol metabolites. Cell 81, 687-695.
13. Gilbert, L.I., Granger, N. A., Roe, R.M., 2000. The juvenile hormones: historical facts and speculations on future research directions. Insect Biochem. Mol. Biol. 30, 617-644.
14. Hall, B.L., Thummel, C.S., 1998. The RXR homolog Ultraspiracle is an essential component of the Drosophila ecdysone receptor. Development 125, 4709-4717.
15. Harmon, M.A., Boehm, M.F., Heyman, R.A., Mangelsdorf, D.J., 1995. Activation of mammalian retinoid X receptors by the insect growth regulator methoprene. Proc. Natl. Acad. Sci. USA 92, 6157-6160.
16. Henrich, V.C., Szekely, A.A., Kim, S.J., Brown, N., Antoniewski, C., Hayden, M.A., Lepesant, J.A., Gilbert, L.I., 1994. Expression and function of the ultraspiracle (usp) gene locus during development in Drosophila melanogaster. Dev. Biol. 165, 38-52.
17. Henrich, V.C., Rybczynski, R., Gilbert, L.I., 1999. Peptide hormones, steroid hormones, and puffs: mechanisms and models in insect development. In: Litwack, G. (Ed.), Vitamins and Hormones, vol. 55. Academic Press, San Diego, pp. 73-125.
18. Henrich, V.C., Vogtli, M., Grebe, M., Przibilla, S., Spindler-Barth, M., Lezzi, M., 2000. Developmental effects of chimeric ultraspiracle gene derived from Drosophila and Chironomus. Genesis 28, 125-133.
19. Hiruma, K., Shinoda, T., Malone, F., Riddiford, L.M., 1999. Juvenile hormone modulates 20-hydroxyecdysone-inducible ecdysone receptor and ultraspiracle gene expression in the tobacco hornworm, Manduca sexta. Dev. Genes Evol. 209, 18-30.
20. Hock, T., Cottrill, T., Keegan, J., Garza, D., 2000. The E23 early gene of Drosophila encodes an ecdysone-inducible ATP-binding cassette transporter capable of repressing ecdysone-mediated gene activation. Proc. Natl. Acad. Sci. USA 15, 9519-9524.
21. Hu, X., Cherbas, L., Cherbas, P., 2003. Transcription activation by the ecdysone receptor: Identification of activation functions in EcR/USP. Mol Endocrinol 17, 716-731.
22. Jin, W., Riley, R.M., Wolfinger, R.D., White, K.P., Passador-Gurgel, G., Gibson, G., 2001. The contributions of sex, genotype, and age to transcriptional variance in Drosophila melanogaster. Nat. Genet. 29, 389-395.
23. Jones, G., Wozniak, M., Chu, Y., Dhar, S., Jones, D., 2001. Juvenile hormone III-dependent conformational changes of the nuclear receptor ultraspiracle. Insect Biochem. Mol. Biol. 32, 33-49.
24. Kitareewan, S., Burka, L.T., Tomer, K.B., Parker, C.E., Deterding, L.J., Stevens, R.D., Forman, B.M., Mais, D.E., Heyman, R.A., McMorris, T., 1996. Phytol metabolites are circulating dietary factors that activate the nuclear receptor RXR. Mol. Biol. Cell. 7, 1153-1196.
25. Koelle, M.R., Talbot, W.S., Segraves, W.A., Bender, M.T., Cherbas, P., Hogness, D.S., 1991. The Drosophila EcR gene encodes an ecdysone receptor, a new member of the steroid receptor superfamily. Cell 67, 59-77.
26. Lezzi, M., Bergman, T., Mouillet, J.-F., Henrich, V.C., 1999. The ecdysone receptor puzzle. Archiv. Insect Biochem. Physiol. 41, 99-106.
27. Louvion, J.-F., Havaux-Copf, B., Picard, D., 1993. Fusion of GAL4-VP16 to a steroid-binding domain provides a tool for gratuitous induction of galactose-responsive genes in yeast. Gene 131, 129-134.
28. Mouillet, J.-F., Henrich, V.C., Lezzi, M., Vogtli, M., 2001. Differential control of gene activity by isoforms A, B1, and B2 of the Drosophila ecdysone receptor. Eur. J. Biochem. 268, 1811-1819.
29. No, D., Yao, T.-P., Evans, R.M., 1996. Ecdysone-inducible gene expression in mammalian cells and transgenic mice. Proc. Natl. Acad. Sci. USA 93, 3346-3351.
30. Oberdorster, E., Clay, M.A., Cottam, D.M., Wilmot, F.A., McLachlan, J.A., Milner, M.J., 2001. Common phytochemicals are ecdysteroid agonists and antagonists: a possible evolutionary link between vertebrate and invertebrate steroid hormones. J. Steroid. Biochem. Mol. Biol. 77, 229-238.
31. Oro, A.E., McKeown, M., Evans, R.M., 1990. Relationship between the product of the Drosophila ultraspiracle locus and the vertebrate retinoid X receptor. Nature 347, 298-301.
32. Palli, S.R., Kaptiskaya, M.Z., Kumar, M.B., Cress, D.E., 2003. Improved ecdysone receptor based inducible gene regulation system. Eur. J. Biochem 27, 1308-1315.
33. Restifo, L.L., Wilson, T.G., 1998. A juvenile hormone agonist reveals distinct developmental pathways mediated by ecdysone-inducible Broad Complex transcription factors. Dev. Genet. 22, 141-159.
34. Richard, D.S., Jones, J.M., Barbarito, M.R., Cerula, S., Detweiler, J.P., Fisher, S.J., Brannigan, D.M., Scheswohl, D.M., 2001. Vitellogenesis in diapausing and mutant Drosophila melanogaster: further evidence for the relative roles of ecdysteroids and juvenile hormones. J. Insect. Physiol. 47, 905-913.
35. Richards, G., 1978. Sequential gene activation by ecdysone in polytene chromosomes of Drosophila melanogaster. Dev. Biol. 66, 32-42.
36. Riddiford, L.M., Ashburner, M., 1991. Effects of juvenile hormone mimics on larval development and metamorphosis of Drosophila melanogaster. Gen. Comp. Endocrinol. 82, 172-183.
37. Riddiford, L.M., 1994. Cellular and molecular actions of juvenile hormone. 1. General considerations and premetamorphic actions. Adv. Insect Physiol. 24, 213-274.
38. Riddiford, L.M., Cherbas, P., Truman, J.W., 2000. Ecdysone receptors and their biological actions. Vitam. Horm. 60, 1-73.
39. Riddihough, G., Pelham, H.R., 1987. An ecdysone response element in the Drosophila hsp27 promoter. EMBO J. 6, 3729-3734.
40. Saez, E., Nelson, M.C., Eshelman, B., Banayo, E., Koder, A., Cho, G.J., Evans, R.M., 2000. Identification of ligands and coligands for the ecdysone regulated switch. Proc. Natl. Acad. Sci. USA 97, 14512-14517.
41. Schmidt, A., Endo, N., Rutledge, S.J., Vogel, R., Shinar, D., Rodan, G.A., 1992. Identification of a new member of the steroid hormone receptor superfamily that is activated by a peroxisome proliferator and fatty acids. Mol. Endocrinol. 6, 1634-1641.
42. Song, Q., Sun, X., Jin, X.Y. 2003. 20E regulated USP expression and phosphorylation in Drosophila melanogaster. Insect Biochem Mol Biol, in press. doi:10.1016/j.ibmb.2003.06.005.
43. Staudinger, J., Goodwin, B., Jones, S.A., Hawkins-Brown, D., MacKenzie, K.I., LaTour, A., Liu, Y., Klaassen, C.D., Brown, K.K., Renhard, J., Wilson, T.M., Koller, B.H., Kliewer, S.A., 2001. The nuclear receptor PXR is a lithocholic acid sensor that protects against liver toxicity. Proc. Natl. Acad. Sci. USA 98, 3369-3374.
44. Talbot, W.S., Swywryd, E.A., Hogness, D.S., 1993. Drosophila tissues with different metamorphic responses to ecdysone express different ecdysone receptor isoforms. Cell 73, 1323-1337.
45. Thomas, H.E., Stunnenberg, H.G., Stewart, A.F., 1993. Heterodimerization of the Drosophila ecdysone receptor with retinoid X receptor and ultraspiracle. Nature 362, 471-475.
46. Thummel, C.S., 2002. Ecdysone-regulated puff genes-2000. Insect Biochem. Mol. Biol. 32, 113-120.
47. Wyatt, G.R., Davey, K.G., 1996. Cellular and molecular actions of juvenile hormone. II. Roles of juvenile hormone in adult insects. Adv. Insect Physiol. 26, 1-155.
48. Xu, Y., Fang, F., Chu, Y., Jones, D., Jones, G., 2002. Activation of transcription through the ligand-binding pocket of the orphan nuclear receptor ultraspiracle. Eur. J. Biochem. 269, 6026-6036.
49. Yao, T.P., Segraves, W.A., Oro, A.E., McKeown, M., Evans, R.M., 1992. Drosophila ultraspiracle modulates ecdysone receptor function via heterodimer formation. Cell 71, 63-72.
50. Yao, T.P., Forman, B.M., Jiang, Z.Y., Cherbas, L., Chen, J.D., McKeown, M., Cherbas, P., Evans, R.M., 1993. Functional ecdysone receptor is the product of EcR and ultraspiracle genes. Nature 366, 476-479.
51. Yamamato, K., Chadarevian, A., Pellegrini, M., 1988. Juvenile hormone action mediated in male accessory glands of Drosophila by calcium and kinase C. Science 239, 916-919.
52. Zhang, Y., Kast-Woelbern, H.R., Edwards, P.A., 2003. Natural structural variants of the nuclear receptor farnesoid X receptor affect transcriptional activation. J. Biol. Chem. 278, 104-110.
53. Zhou, X., Riddiford, L.M., 2002. Broad specifies pupal development and mediates the 'status quo' action of juvenile hormone on the pupal-adult transformation in Drosophila and Manduca. Development 1290, 2259-2269.