Proteomic identification of PKC-mediated expression of 20E-induced protein in Drosophila melanogaster

Journal of Proteome Research

Volumn 6, Issue 11, 2007, Pages 4478-4488

  Sun, Yaning ^a   An, Shiheng ^a   Henrich, Vincent C ^b   Sun, Xiaoping ^c   Song, Qisheng ^a  

^a UNIVERSITY OF MISSOURI   (United States)

^b UNIVERSITY OF NORTH CAROLINA AT GREENSBORO   (United States)

^c NATIONAL INSTITUTE ON AGING   (United States)

Author keywords

Inhibitor; Nuclear receptor; Protein expression; Protein kinase

Indexed keywords

CELL NUCLEUS RECEPTOR; ECDYSONE RECEPTOR; ECDYSTERONE; HETERODIMER; PROTEIN KINASE C;

ARTICLE; CELL FUNCTION; CELL PROTECTION; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DROSOPHILA MELANOGASTER; GENE CONTROL; GENETIC TRANSCRIPTION; IMMUNOHISTOCHEMISTRY; LARVA; LIPID METABOLISM; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DATA BANK; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEOMICS; RNA EXTRACTION; SALIVARY GLAND; WESTERN BLOTTING;

ANIMALS; BLOTTING, WESTERN; CELL NUCLEUS; CYTOSOL; DIMERIZATION; DOSE-RESPONSE RELATIONSHIP, DRUG; DROSOPHILA MELANOGASTER; ECDYSTERONE; GENE EXPRESSION REGULATION, ENZYMOLOGIC; PHOSPHORYLATION; PROTEIN KINASE C; PROTEOMICS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; TRANSCRIPTION, GENETIC;

DROSOPHILA MELANOGASTER; HEXAPODA;

EID: 36348986756     PISSN: 15353893     EISSN: None     Source Type: Journal    
DOI: 10.1021/pr0705183     Document Type: Article

References (38)

1. Riddiford, L. M.; Cherbas, P.; Truman, J. W. Ecdysone receptors and their biological actions. Vitam. Horm. 2000, 60, 1-73.
2. Henrich, V. The ecdysteroid receptor. In Comprehensive Molecular Insect Science; Gilbert, L. I., Ed.; Elsevier, Pergamon: Oxford, 2005; pp 243-285.
3. Weigel, N. L. Steroid hormone receptors and their regulation by phosphorylation. Biochem. J. 1996, 319, 657-667.
4. Lange, C. A. Making sense of cross-talk between steroid hormone receptors and intracellular signaling pathways: who will have the last word? Mol. Endocrinol. 2004, 18, 269-278.
5. Song, Q.; Gilbert, L. I. Alterations in ultraspiracle (USP) content and phosphorylation state accompany feedback regulation of ecdysone synthesis in the insect prothoracic gland. Insect Biochem. Mol. Biol. 1998, 28, 849-860.
6. Rauch, P.; Grebe, M.; Elke, C.; Spindler, K. D. Spindler-Barth, M. Ecdysteroid receptor and ultraspiracle from Chironomus tentans (Insecta) are phosphoproteins and are regulated differently by molting hormone. Insect Biochem. Mol. Biol. 1998, 28, 265-275.
7. Nicolaï, N.; Bouhin, H.; Quennedey, B.; Delachambre, J. Molecular cloning and expression of Tenebrio molotor ultraspiracle during metamorphosis and in vivo induction of its phosphorylation by 20-hydroxyecdysone. Insect Mol. Biol. 2000, 9, 242-249.
8. Song, Q.; Sun, X; Jin, X. Y. 20E-regulated USP expression and phosphorylation in Drosophila melanogaster. Insect Biochem. Mol. Biol. 2003, 33, 1211-1218.
9. Thummel, C. S. Ecdysone-regulated puff genes 2000. Insect Biochem. Mol. Biol. 2002, 32, 113-120.
10. Sun, X.; Song, Q. PKC-mediated USP phosphorylation is required for 20E-induced gene expression in the salivary glands of Drosophila melanogaster. Arch. Insect Biochem. Physiol. 2006, 62, 116-127.
11. Ron, D.; Jiang, Z.; Yao, L.; Vagts, A.; Diamond, I.; Gordon, A. Coordinated movement of RACK1 with activated βIIPKC J. Biol. Chem. 1999, 274, 27039-27046.
12. Rigas, A. C.; Ozanne, D. M.; Neal, D. E.; Robson, C. N. The scaffolding protein RACK1 interacts with androgen receptor and promotes cross-talk through a protein kinase C signaling pathway. J. Biol. Chem. 2003, 278, 46087-46093.
13. Quan, G. X.; Krell, P. J.; Arif, B. M.; Feng, Q. Receptor of activated C kinase 1 (RACK1) is necessary for the 20-hydroxyecdysone-induced expression of the transcription factor CHR3 in the spruce budworm Choristoneura fumiferana. Insect Mol. Biol. 2006, 15 (1), 79-87.
14. Andres, A. J.; Thummel, C. S. Methods for quantitative analysis of transcription in larvae and prepupae. Methods Cell Biol. 1994, 44, 565-573.
15. Alnemri, E. S.; Fernandes-Alnemri, T. D.; Nelki, S.; Dudley, K.; DuBois, G. C.; Litwack, G. Overexpression, characterization and purification of a recombinant mouse immunophilin FKBP-52 and identification of an associated phosphoprotein. Proc. Natl. Acad. Sci. 1993, 90 (14), 6839-6843.
16. Havlis, J.; Thomas, H.; Sÿ, ebela, M.; Shevchenko, A. Fast-response proteomics by accelerated in-gel digestion of proteins. Anal. Chem. 2003, 75, 1300-1306.
17. Jiménez, C. R.; Huang, L.; Qiu, Y.; Burlingame, A. L. In-gel digestion of proteins for MALDI-MS fingerprint mapping. In Current Protocols in Protein Science; Coligan, J. E., Ed.; John Wiley & Sons, Inc.: Brooklyn, NY, 1998; pp 16.4.1-16.4.5.
18. Livak, K. J.; Schmittgen, T. D. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 2001, 25, 402-408.
19. Hiruma, K.; Riddiford, L. M. Differential control of MHR3 promoter activity by isoforms of the ecdysone receptor and inhibitory effects of E75A and MHR3. Dev. Biol. 2004, 272, 510-521.
20. Karim, F. D.; Thummel, C. S. Ecdysone coordinates the timing and amounts of E74A and E74B transcription in Drosophila. Genes Dev. 1991, 5, 1067-1079.
21. Burmester, T.; Antoniewski, C.; Lepesant J. A. Ecdysone-regulation of synthesis and processing of Fat Body Protein 1, the larval serum protein receptor of Drosophila melanogaster. Eur. J. Biochem. 1999, 262 (1), 49-55.
22. Arbeitman, M. N.; Hogness, D. S. Molecular chaperones activate the Drosophila ecdysone receptor, an RXR heterodimer. Cell 2000, 101, 67-77.
23. Pratt, W. B.; Toft, D. O. Steroid receptor interactions with heat shock protein and immunophilin chaperones. Endocr. Rev. 1997, 18, 306-360.
24. Cheung, J.; Smith, D. F. Molecular chaperone interactions with steroid receptors: an update. Mol. Endocrinol. 2000, 14, 939-946.
25. Wu, R. C.; Qin, J.; Yi, P.; Wong, J.; Tsai, S. Y.; Tsai, M. J.; O'Malley, B. W. Selective phosphorylations of the SRC-3/AIB1 coactivator integrate genomic reponses to multiple cellular signaling pathways. Mol. Cell 2004, 15, 937-949
26. Lopez, G. N.; Turck, C. W.; Schaufele, F.; Stallcup, M. R.; Kushner, P. J. Growth factors signal to steroid receptors through mitogen-activated protein kinase regulation of p160 coactivator activity. J. Biol. Chem. 2001, 276, 22177-22182
27. Weigel, N. L.; Zhang, Y. Ligand-independent activation of steroid hormone receptors. J. Mol. Med. 1998, 76, 469-479.
28. Rowan, B. G.; Garrison, N.; Weigel, N. L.; O'Malley, B. W. 8-Bromo-cyclic AMP induces phosphorylation of two sites in SRC-1 that facilitate ligand-independent activation of the chicken progesterone receptor and are critical for functional cooperation between SRC-1 and CREB binding protein. Mol. Cell. Biol. 2000, 20, 8720-8730.
29. Nieva, C.; Gwozdz, T.; Dutko-Gwozdz, J.; Wiedenmann, J.; Spindler-Barth, M.; Wieczorek, E.; Dobrucki, J.; Dus, D.; Henrich, V.; Ozyhar, A.; Spindler, K. D. Ultraspiracle promotes the nuclear localization of ecdysteroid receptor in mammalian cells. Biol. Chem. 2005, 386, 463-470.
30. Hill, R. J.; Watt, F.; Yund, M. A.; Fristrom, J. W. The effect of 20-hydroxyecdysone on synthesis of chromosomal and cytosol proteins in imaginal discs. Dev. Biol. 1982, 90, 340-351.
31. Ron, D.; Chen, C. H.; Caldwell, J.; Jamieson, L.; Orr, E.; Mochly-Rosen, D. Cloning of an intracellular receptor for protein kinase C: a homolog of the β subunit of G proteins. Proc. Natl. Acad. Sci. 1994, 91, 839-843.
32. Ron, D.; Luo, J.; Mochly-Rosen, D. C2 region-derived peptides inhibit translocation and function of beta protein kinase C in vivo. J.. Biol. Chem. 1995, 270, 24180-24187.
33. Yarwood, S. J.; Steele, M. R.; Scotland, G.; Houslay, M. D.; Bolger, G. B. The RACK1 signaling scaffold protein selectively interacts with the cAMP-specific phosphodiesterase PDE4D5 isoform. J. Biol. Chem. 1999, 274, 14909-14917.
34. Chang, B. Y.; Conroy, K. B.; Machleder, E. M.; Cartwright, C. A. RACK1, a receptor for activated C kinase and a homolog of the β subunit of G proteins, inhibits activity of Src tyrosine kinases and growth of NIH 3T3 cells. Mol. Cell. Biol. 1998, 18, 3245-3256.
35. McCahill, A.; Warwicker, J.; Bolger, G. B.; Houslay, M. D.; Yarwood, S. J. The RACK1 scaffold protein: a dynamic cog in cell response mechanisms. Mol. Pharmacol. 2002, 62, 1261-1273.
36. Tsuzuki, S.; Iwami, M.; Sakurai, S. Ecdysteroid-inducible genes in the programmed cell death during insect metamorphosis. Insect Biochem. Mol. Biol. 2001, 31, 321-331.
37. Antoniewski, C.; Laval, M.; Dahan, A.; Lepesant, J. A. The ecdysone response enhancer of the Fbp1 gene of Drosophila melanogaster is a direct target for the EcR/USP nuclear receptor. Mol. Cell. Biol. 1994, 14 (7), 4465-4474.
38. Shieh, B. H.; Parker, L.; Popescu, D. Protein kinase C (PKC) isoforms in Drosophila. J. Biochem. 2002, 132 (4), 523-527.