The diabetic intrauterine environment: Short and long-term consequences

Gestational Diabetes During and After Pregnancy

Volumn , Issue , 2010, Pages 227-239

  Dabelea, Dana ^a  

^a Food Science and Human Nutrition   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 84882450477     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1007/978-1-84882-120-0_16     Document Type: Chapter

References (89)

1. Hussain A, Claussen B, Ramachandran A., Williams R. Prevention of type 2 diabetes: a review. Diabetes Res Clin Pract. 2007; 76: 317-326.
2. Dabelea D, Pettitt DJ, Jones K.L., Arslanian SA Type 2 diabetes mellitus in minority children and adolescents. An emerging problem. Endocrinol Metab Clin North Am. 1999; 28(9): 709-729.
3. Dabelea D, Snell-Bergeon JK, Hartsfield C.L., Bischoff KJ, Hamman RF, McDuffie RS Increasing prevalence of gestational diabetes mellitus (GDM) over time and by birth cohort: Kaiser Permanente of Colorado GDM Screening Program. Diab Care. 2005; 28: 579-584.
4. Ferrarra A, Kahn HS, Quesenberry C.P., Riley C., Hedderson MM An increase in the incidence of gestational diabetes mellitus: Northern California, 1991-2000. Obstet Gynecol. 2004; 103: 526-533.
5. Sobngwi E, Boudou P, Mauvais-Jarvis F. Effect of a diabetic environment in utero on predisposition to type 2 diabetes. Lancet. 2003; 361: 1861-1865.
6. Pedersen J. Weight and lenght at birth in infants of diabetic mothers. Acta Endocrinol. 1954; 16: 330-342.
7. Freinkel N. Banting Lecture 1980 Of pregnancy and progeny. Diabetes. 1980; 29: 1023-1035.
8. Whitaker RC, Dietz WH Role of the prenatal environment in the development of obesity. J Pediatr. 1998; 132: 768-776.
9. Barker DJ, Fall CH Fetal and infant origins of cardiovascular disease. Arch Dis Child. 1993; 68: 797-799.
10. Barker DJ, Gluckman PD, Godfrey K.M., Harding JE, Owens JA, Robinson JS Fetal nutrition and cardiovascular disease in adult life [see comments]. Lancet. 1993; 341: 938-941.
11. Barker DJ. In utero programming of chronic disease. Clin Sci (Colch). 1998; 95: 115-128.
12. Aerts L, Sodoyez-Goffaux F, Sodoyez J.C., Malaisse WJ, Van Assche FA. The diabetic intra-uterine milieu has a long-lasting effect on insulin secretion by B cells and on insulin uptake by target tissues. Am J Obstet Gynecol. 1988; 159: 1287-1292.
13. Gauguier D, Nelson I, Bernard C. Higher maternal than paternal inheritance of diabetes in GK rats. Diabetes. 1994; 43: 220-224.
14. Lampl M, Jeanty P. Exposure to maternal diabetes is associated with altered fetal growth patterns: A hypothesis regarding metabolic allocation to growth under hyperglycemic-hypoxemic conditions. Am J Hum Biol. 2004; 6: 237-263.
15. Jansson T, Cetin I, Powell TL Placental transport and metabolism in fetal overgrowth - a workshop report. Placenta. 2006; 27(suppl A): S109-S113.
16. Catalano PM, Thomas A, Huston-Presley L, Amini SB Increased fetal adiposity: a very sensitive marker of abnormal in utero development. Am J Obstet Gynecol. 2003; 189: 1698-1704.
17. Perry IJ, Lumey LH In: Kuh D, Ben-Shlomo Y, eds. A Life Course Approach to Chronic Disease Epidemiology. Oxford: Oxford University Press; 2004: 345.
18. Luke B. Nutritional influences on fetal growth. Clin Obstet Gynecol. 1994; 37: 538-549.
19. Abrams BF, Berman CA Nutrition during pregnancy and lactation. Prim Care. 1993; 20: 585-597.
20. Vohr BR, McGarvey ST, Coll CG Effects of maternal gestational diabetes and adiposity on neonatal adiposity and blood pressure. Diabetes Care. 1995; 18: 467-475.
21. Vohr BR, McGarvey ST Growth patterns of large-for-gestational-age and appropriate-for-gestational-age infants of gestational diabetic mothers and control mothers at age 1 year. Diabetes Care. 1997; 20: 1066-1072.
22. Catalano PM, Kirwan JP Maternal factors that determine neonatal size and body fat. Curr Diab Rep. 2001; 1: 71-77.
23. Ouzilleau C, Roy MA, Leblanc L, Carpentier A., Maheux P. An observational study comparing 2-hour 75-g oral glucose tolerance with fasting plasma glucose in pregnant women: both poorly predictive of birth weight. CMAJ. 2003; 168: 403-409.
24. Catalano PM, Kirwan JP, Haugel-de Mouzon S, King J. Gestational diabetes and insulin resistance: role in short- and long-term implications for mother and fetus. J Nutr. 2003; 133: 1674S-1683S.
25. Brown JE, Potter JD, Jacobs DR Jr. Maternal waist-to-hip ratio as a predictor of newborn size: results of the Diana Project. Epidemiology. 1996; 7: 62-66.
26. McKeigue PM, Pierpoint T, Ferrie J.E., Marmot MG Relationship of glucose intolerance and hyperinsulinaemia to body fat pattern in South Asians and Europeans. Diabetologia. 1992; 35: 785-791.
27. Fowden AL. The role of insulin in prenatal growth. J Dev Physiol. 1989; 12: 173-182.
28. Langer O, Conway DL Level of glycemia and perinatal outcome in pregestational diabetes. J Matern Fetal Med. 2000; 9: 35-41.
29. Langer O. Fetal macrosomia: etiologic factors. Clin Obstet Gynecol. 2000; 43: 283-297.
30. Langer O, Yogev Y, Most O., Xenakis EM Gestational diabetes: the consequences of not treating. Am J Obstet Gynecol. 2005; 192: 989-997.
31. Ratner RE. Clinical review 47: gestational diabetes mellitus: after three international workshops do we know how to diagnose and manage it yet? J Clin Endocrinol Metab. 1993; 77: 1-4.
32. Jarrett RJ. Gestational diabetes: a non-entity? Brit Med J. 1993; 306: 37-38.
33. Buchanan TA, Kjos SL Gestational diabetes: risk or myth? J Clin Endocrinol Metab. 1999; 84: 1854-1857.
34. Kjos SL, Buchanan TA Gestational diabetes mellitus. N Engl J Med. 1999; 341: 1749-1756.
35. Dornhorst A, Chan SP The elusive diagnosis of gestational diabetes. Diabet Med. 1998; 15: 7-10.
36. Ferrara A, Hedderson MM, Quesenberry C.P., Selby J V. Prevalence of gestational diabetes mellitus detected by the national diabetes data group or the carpenter and coustan plasma glucose thresholds. Diabetes Care. 2002; 25: 1625-1630.
37. Sermer M, Naylor CD, Gare DJ Impact of increasing carbohydrate intolerance on maternal-fetal outcomes in 3637 women without gestational diabetes. The Toronto Tri-Hospital Gestational Diabetes Project. Am J Obstet Gynecol. 1995; 173: 146-156.
38. Leikin EL, Jenkins JH, Pomerantz G.A., Klein L. Abnormal glucose screening tests in pregnancy: a risk factor for fetal macrosomia. Obstet Gynecol. 1987; 69: 570-573.
39. Yogev Y, Langer O, Xenakis E.M., Rosenn B. The association between glucose challenge test, obesity and pregnancy outcome in 6390 non-diabetic women. J Matern Fetal Neonatal Med. 2005; 17: 29-34.
40. Hill JC, Krishnaveni GV, Annamma I, Leary S.D., Fall CH Glucose tolerance in pregnancy in South India: relationships to neonatal anthropometry. Acta Obstet Gynecol Scand. 2005; 84: 159-165.
41. Farmer G, Russell G, Hamilton-Nicol DR. The influence of maternal glucose metabolism on fetal growth, development and morbidity in 917 singleton pregnancies in nondiabetic women. Diabetologia. 1988; 31: 134-141.
42. The HAPOStudy Cooperative Research Group. Hyperglycemia and adverse pregnancy outcomes. New Engl J Med. 2008; 358: 1991-2002.
43. Rey E, Attie C, Bonin A. The effects of first-trimester diabetes control on the incidence of macrosomia. Am J Obstet Gynecol. 1999; 181: 202-206.
44. Illsley NP. Glucose transporters in the human placenta. Placenta. 2000; 21: 14-22.
45. Illsley NP. Placental glucose transport in diabetic pregnancy. Clin Obstet Gynecol. 2000; 43: 116-126.
46. Gaither K, Quraishi AN, Illsley NP Diabetes alters the expression and activity of the human placental GLUT1 glucose transporter. J Clin Endocrinol Metab. 1999; 84: 695-701.
47. Butte NF. Carbohydrate and lipid metabolism in pregnancy: normal compared with gestational diabetes mellitus. Am J Clin Nutr. 2000; 71: 1256S-1261S.
48. Di Cianni G., Miccoli R, Volpe L. Maternal triglyceride levels and newborn weight in pregnant women with normal glucose tolerance. Diabet Med. 2005; 22: 21-25.
49. Bo S, Menato G, Gallo ML Mild gestational hyperglycemia, the metabolic syndrome and adverse neonatal outcomes. Acta Obstet Gynecol Scand. 2004; 83: 335-340.
50. Nolan CJ, Proietto J. The feto-placental glucose steal phenomenon is a major cause of maternal metabolic adaptation during late pregnancy in the rat. Diabetologia. 1994; 37: 976-984.
51. Kitajima M, Oka S, Yasuhi I., Fukuda M, Rii Y, Ishimaru T. Maternal serum triglyceride at 24-32 weeks' gestation and newborn weight in nondiabetic women with positive diabetic screens. Obstet Gynecol. 2001; 97: 776-780.
52. Knopp RH, Magee MS, Walden C.E., Bonet B., Benedetti TJ Prediction of infant birth weight by GDM screening tests. Importance of plasma triglyceride. Diabetes Care. 1992; 15: 1605-1613.
53. Peterson CM, Jovanovic-Peterson L, Mills JL The Diabetes in Early Pregnancy Study: changes in cholesterol, triglycerides, body weight, and blood pressure. The National Institute of Child Health and Human Development-the Diabetes in Early Pregnancy Study. Am J Obstet Gynecol. 1992; 166: 513-518.
54. Catalano PM, Vargo KM, Bernstein I.M., Amini SB Incidence and risk factors associated with abnormal postpartum glucose tolerance in women with gestational diabetes. Am J Obstet Gynecol. 1991; 165: 914-919.
55. Cousins L. Insulin sensitivity in pregnancy. Diabetes. 1991; 40(SUPPL. 2):39-43.
56. Barbour LA. New concepts in insulin resistance of pregnancy and gestational diabetes: long-term implications for mother and offspring. J Obstet Gynaecol. 2003; 23: 545-549.
57. Catalano PM, Tyzbir ED, Wolfe R.R., Roman NM, Amini SB, Sims EA Longitudinal changes in basal hepatic glucose production and suppression during insulin infusion in normal pregnant women. Am J Obstet Gynecol. 1992; 167: 913-919.
58. Catalano PM, Tyzbir ED, Wolfe RR Carbohydrate metabolism during pregnancy in control subjects and women with gestational diabetes. Am J Physiol. 1993; 264: E60-E67.
59. Catalano PM, Tyzbir ED, Roman N.M., Amini SB, Sims EA Longitudinal changes in insulin release and insulin resistance in nonobese pregnant women. Am J Obstet Gynecol. 1991; 165: 1667-1672.
60. Kirwan JP, Hauguel-De MS, Lepercq J. TNF-alpha is a predictor of insulin resistance in human pregnancy. Diabetes. 2002; 51: 2207-2213.
61. Ford ES. Body mass index, diabetes, and C-reactive protein among U.S. adults. Diabetes Care. 1999; 22: 1971-1977.
62. Yudkin JS. Abnormalities of coagulation and fibrinolysis in insulin resistance. Evidence for a common antecedent? Diab Care. 1999; 22(SUPPL. 3): C25-C30.
63. Ramsay JE, Ferrell WR, Crawford L, Wallace A.M., Greer IA, Sattar N. Maternal obesity is associated with dysregulation of metabolic, vascular, and inflammatory pathways. J Clin Endocrinol Metab. 2002; 87: 4231-4237.
64. Retnakaran R, Hanley AJ, Raif N, Connelly P.W., Sermer M., Zinman B. C-reactive protein and gestational diabetes: the central role of maternal obesity. J Clin Endocrinol Metab. 2003; 88: 3507-3512.
65. Ramsay JE, Stewart F, Greer I.A., Sattar N. Microvascular dysfunction: a link between pre-eclampsia and maternal coronary heart disease. BJOG. 2003; 110: 1029-1031.
66. Forsen T, Eriksson JG, Tuomilehto J, Teramo K., Osmond C, Barker DJ Mother's weight in pregnancy and coronary heart disease in a cohort of Finnish men: follow up study. Brit Med J. 1997; 315: 837-840.
67. Dahlgreen J, Nilsson C, Jennische E., et al Prenatal cytokine exposure results in obesity and gender-specific programming. Am J Physiol Endocrinol Metab. 2001; 281: E326-E334.
68. Pettitt DJ, Knowler WC Diabetes and obesity in the Pima Indians: a crossgenerational vicious cycle. J Obesity Weight Regul. 1988; 7: 61-65.
69. Pettitt DJ, Knowler WC, Bennett P.H., Aleck KA, Baird HR Obesity in offspring of diabetic Pima Indian women despite normal birth weight. Diabetes Care. 1987; 10: 76-80.
70. Harder T, Kohlhoff R, Dorner G., Rohde W, Plagemann A. Perinatal 'programming' of insulin resistance in childhood: critical impact of neonatal insulin and low birth weight in a risk population. Diabet Med. 2001; 18: 634-639.
71. Silverman BL, Metzger BE, Cho N.H., Loeb CA Impaired glucose tolerance in adolescent offspring of diabetic mothers: Relationship to fetal hyperinsulinism. Diabetes Care. 1995; 18: 611-617.
72. Weiss PA, Scholz HS, Haas J, Tamussino K.F., Seissler J., Borkenstein MH Long-term follow-up of infants of mothers with type 1 diabetes: evidence for hereditary and nonhereditary transmission of diabetes and precursors. Diabetes Care. 2000; 23: 905-911.
73. Pettitt DJ, Nelson RG, Saad M.F., Bennett PH, Knowler WC Diabetes and obesity in the offspring of Pima Indian women with diabetes during pregnancy. Diabetes Care. 1993; 16: 310-314.
74. Pettitt DJ, Baird HR, Aleck K.A., Bennett PH, Knowler WC Excessive obesity in offspring of Pima Indian women with diabetes during pregnancy. New Engl J Med. 1983; 308: 242-245.
75. Pettitt DJ, Bennett PH, Knowler W.C., Baird HR, Aleck KA Gestational diabetes mellitus and impaired glucose tolerance during pregnancy. Long-term effects on obesity and glucose tolerance in the offspring Diabetes. 1985; 34(SUPPL. 2):119-122.
76. Silverman BL, Rizzo T, Green OC Long-term prospective evaluation of offspring of diabetic mothers. Diabetes. 1991; 40(SUPPL. 2):121-125.
77. Gillman MW, Rifas-Shiman S, Berkey C.S., Field AE, Colditz GA Maternal gestational diabetes, birth weight, and adolescent obesity. Pediatrics. 2003; 111: e221-e226.
78. Whitaker RC, Pepe MS, Seidel K.D., Wright JA, Knopp RH Gestational diabetes and the risk of offspring obesity. Pediatrics. 1998; 101: E91-E97.
79. Dabelea D, Pettitt DJ Intrauterine diabetic environment confers risks for type 2 diabetes mellitus and obesity in the offspring, in addition to genetic susceptibility. J Pediatr Endocrinol Metab. 2001; 14: 1085-1091.
80. Dabelea D, Hanson RL, Lindsay RS Intrauterine exposure to diabetes conveys risks for type 2 diabetes and obesity: a study of discordant sibships. Diabetes. 2000; 49: 2208-2211.
81. Dabelea D, Mayer-Davis EJ, Lamichhane AP Association of intrauterine exposure to maternal diabetes and obesity with type 2 diabetes in youth: the SEARCH Case-Control Study. Diab Care. 2008; 31: 1422-1426.
82. Pildes RS, Hart RJ, Warrner R, Cornblath M. Plasma insulin response during oral glucose tolerance tests in newborns of normal and gestational diabetic mothers. Pediatrics. 1969; 44: 76-83.
83. Van Assche F.A., Gepts W. The cytological composition of the foetal endocrine pancreas in normal and pathological conditions. Diabetologia. 1971; 7: 434-444.
84. Heding LG, Persson B, Stangenberg M. B-cell function in newborn infants of diabetic mothers. Diabetologia. 1980; 19: 427-432.
85. Gautier JF, Wilson C, Weyer C. Low acute insulin secretory responses in adult offspring of people with early onset type 2 diabetes. Diabetes. 2001; 50: 1828-1833.
86. Holemans K, Gerber RT, Meurrens K, De Clerck F, Poston L, Van Assche FA. Streptozotocin diabetes in the pregnant rat induces cardiovascular dysfunction in adult offspring. Diabetologia. 1999; 42: 81-89.
87. Manderson JG, Mullan B, Patterson C.C., Hadden DR, Traub AI, McCance DR Cardiovascular and metabolic abnormalities in the offspring of diabetic pregnancy. Diabetologia. 2002; 45: 991-996.
88. Bunt JC, Tataranni PA, Salbe AD Intrauterine exposure to diabetes is a determinant of hemoglobin A(1)c and systolic blood pressure in pima Indian children. J Clin Endocrinol Metab. 2005; 90: 3225-3229.
89. Crowther CA, Hiller JE, Moss J.R., McPhee AJ, Jeffries WS, Robinson JS Effect of treatment of gestational diabetes mellitus on pregnancy outcomes. N Engl J Med. 2005; 352: 2477-2486.