Simulations of cyclic breathing in the conducting zone of the human lung

American Society of Mechanical Engineers, Fluids Engineering Division (Publication) FEDSM

Volumn 1, Issue PARTS A AND B, 2012, Pages 863-871

  Walters, D Keith ^a   Burgreen, Greg W ^b   Hester, Robert L ^c   Thompson, David S ^a   Lavallee, David M ^a   Pruett, William A ^c   Ford Green, Jason ^c  

^a MISSISSIPPI STATE UNIVERSITY   (United States)

^b MISSISSIPPI STATE UNIVERSITY   (United States)

^c UNIVERSITY OF MISSISSIPPI MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AIR; ATMOSPHERIC MOVEMENTS; BIOLOGICAL ORGANS; COMPUTATIONAL FLUID DYNAMICS; COMPUTATIONAL GEOMETRY; DIGITAL STORAGE; MASS TRANSFER; PHYSIOLOGICAL MODELS; RESPIRATORY SYSTEM;

AIR FLOW; AIRWAY GENERATION; COMPUTATIONAL FLUID DYNAMICS SIMULATIONS; CT-SCAN; FLOW DISTRIBUTION; HUMAN LUNG; MASS FLOW; PATIENT SPECIFIC; SCAN DATA; UPPER AIRWAY;

COMPUTERIZED TOMOGRAPHY;

EID: 84882356581     PISSN: 08888116     EISSN: None     Source Type: Conference Proceeding    
DOI: 10.1115/FEDSM2012-72474     Document Type: Conference Paper

References (17)

1. Walters, D.K. and Luke, W.H., 2010, "A Method for Three-Dimensional Navier-Stokes Simulations of Large-Scale Regions of the Human Lung Airway," ASME Journal of Fluids Engineering, Vol. 132, No. 051101.
2. Walters, D.K. and Luke, W.H., 2011, "Computational Fluid Dynamics Simulations of Particle Deposition in Large-Scale, Multi-Generational Lung Models," ASME Journal of Biomechanical Engineering, Vol. 133, No. 011003.
3. Walters, D.K., Burgreen, G.W., Lavallee, D.M., Thompson, D.S., and Hester, R.L., 2011, "Efficient, Physiologically Realistic Lung Airflow Simulations," IEEE Transactions in Biomedical Engineering, Vol. 58, No. 10, pp. 3016-3019.
4. Ma, B., and Lutchen, K.R., 2006, "An Anatomically Based Hybrid Computational Model of the Human Lung and its Application to Low Frequency Oscillatory Mechanics," Annals of Biomedical Engineering, 34(11), pp. 1691-1704.
5. Gemci, T., Ponyavin, V., Chen, Y., Chen, H., and Collins, R., 2008, "Computational Model of Airflow in Upper 17 Generations of Human Respiratory Tract," Journal of Biomechanics, 41(9), pp. 2047-2054.
6. Nowak, N., Kadake, P.P., and Annapragada, A.V., 2003, "Computational Fluid Dynamics Simulation of Airflow and Aerosol Deposition in Human Lungs," Annals of Biomedical Engineering, 31(4), pp. 374-390.
7. Zhang, Z., Kleinstreuer, C., and Kim C.S., 2008, "Airflow and Nanoparticle Deposition in a 16-Generation Tracheobronchial Airway Model," Annals of Biomedical Engineering, 36(12), pp. 2095-2110.
8. Tian, G., Longest, P.W., Su, G., Walenga, R.L. and Hindle, M., "Development of a Stochastic Individual Path (SIP) Model for Predicting the Tracheobronchial Deposition of Pharmaceutical Aerosols: Effects of Transient Inhalation and Sampling the Airways," Journal of Aerosol Science, Vol. 42(11), pp. 781-799.
9. Gaither, J. A., Marcum, D. L. and Mitchell, B. (2000) 'SolidMesh: A Solid Modeling Approach to Unstructured Grid Generation,' Proceedings of the 7th International Conference on Numerical Grid Generation in Computational Field Simulations, Whistler, BC, September.
10. A. Schmidt, S. Zidowitz, A. Kriete, et al. "A digital reference model of the human bronchial tree," Computerized Medical Imaging and Graphics, Vol 28, pp. 203-211, 2004.
11. H.-C. Yeh and G. M. Schum, "Models of human lung airways and their application to inhaled particle deposition," Bulletin of Mathematical Biology, Vol. 42, pp. 461-480, 1980.
12. P. W. Longest and S. Vinchurkar, "Validating CFD predictions of respiratory aerosol deposition: Effects of upstream transition and turbulence," Journal of Biomechanics, Vol. 40, pp. 305-316, 2007.
13. Hester, R.L., Brown, A.J., Husband, L., Iliescu, R., Pruett, D., Summers, R. and Coleman, T.G., 2011, "HumMod: A Modeling Environment for the Simulation of Integrative Human Physiology," Frontiers in Physiology, Vol. 2, No. 12, Article 12, 12p.
14. Guyton, A.C. and Coleman, T.G., 1969, "Quantitative Analysis of the Pathophysiology of Hypertension," Circulation Research, Vol. 24, pp. 1-19.
15. Soni, B., Lindley, C., and Thompson, D., 2009, "The Combined Effects of Non-Planarity and Asymmetry on Primary and Secondary Flows in the Small Bronchial Tubes," International Journal for Numerical Methods in Fluids, Vol. 59, pp. 117-146.
16. Pedley, T.J., Schroter, R.C. and Sudlow, M.F., 1970, "The Prediction of Pressure Drop and Variation of Resistance Within the Human Bronchial Airways,", Respiration Physiology, Vol. 9, pp. 387-405.
17. Kitaoka, H., Takaki, R. and Suki B, 1999, "A Three Dimensional Model for Human Airway Tree," Journal of Applied Physiology, Vol. 76, pp. 2207-2217.