Stronger antinociceptive efficacy of opioids at the injured nerve trunk than at its peripheral terminals in neuropathic pain

Journal of Pharmacology and Experimental Therapeutics

Volumn 346, Issue 3, 2013, Pages 535-544

  Labuz, Dominika ^a   Machelska, Halina ^a  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

3,4 DICHLORO N METHYL N [2 (1 PYRROLIDINYL)CYCLOHEXYL]BENZENEACETAMIDE; ENKEPHALIN[2 DEXTRO ALANINE 4 METHYLPHENYLALANINE 5 GLYCINE]; ENKEPHALIN[2,5 DEXTRO PENICILLAMINE];

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINOCICEPTION; ARTICLE; DOSE RESPONSE; DRUG EFFECT; DRUG EFFICACY; HEAT SENSITIVITY; INNERVATION; LATENT PERIOD; MALE; MOUSE; NERVE TRACT; NEUROPATHIC PAIN; NONHUMAN; PAIN THRESHOLD; PERIPHERAL NERVE INJURY; PRIORITY JOURNAL; SCIATIC NERVE INJURY; TREATMENT DURATION;

3,4-DICHLORO-N-METHYL-N-(2-(1-PYRROLIDINYL)-CYCLOHEXYL)-BENZENEACETAMIDE, (TRANS)-ISOMER; ANALGESICS, OPIOID; ANIMALS; BEHAVIOR, ANIMAL; CONSTRICTION, PATHOLOGIC; ENKEPHALIN, ALA(2)-MEPHE(4)-GLY(5)-; ENKEPHALIN, D-PENICILLAMINE (2,5)-; FOOT; HOT TEMPERATURE; HYPERALGESIA; MALE; MICE; MICE, INBRED C57BL; NERVE ENDINGS; NEURALGIA; PAIN MEASUREMENT; PERIPHERAL NERVE INJURIES; PERIPHERAL NERVES; PHYSICAL STIMULATION; RECEPTORS, OPIOID;

EID: 84882339653     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.113.205344     Document Type: Article

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