Dynamic temporal and spatial regulation of mu opioid receptor expression in primary afferent neurons following spinal nerve injury

European Journal of Pain

Volumn 15, Issue 7, 2011, Pages 669-675

  Lee, Chun Yi ^a,b   Perez, Federico M ^c   Wang, Wei ^a,d   Guan, Xiaowei ^a   Zhao, Xiuli ^a   Fisher, Janet L ^c   Guan, Yun ^a   Sweitzer, Sarah M ^c   Raja, Srinivasa N ^a   Tao, Yuan Xiang ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b TAIPEI VETERANS GENERAL HOSPITAL   (Taiwan)

^c UNIVERSITY OF SOUTH CAROLINA SCHOOL OF MEDICINE   (United States)

^d FOURTH MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Dorsal root ganglion; Expression; Mu opioid receptors; Peripheral nerve injury; Skin; Spinal cord

Indexed keywords

MESSENGER RNA; MU OPIATE RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; IMMUNOHISTOCHEMISTRY; LUMBOSACRAL SPINE; MALE; NERVE LIGATION; NEUROPATHIC PAIN; NONHUMAN; PERIPHERAL NERVE INJURY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RAT; RECEPTOR DOWN REGULATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SENSORY NERVE; SHAM PROCEDURE; SPINAL CORD; SPINAL GANGLION; SPINAL NERVE; TIME; WESTERN BLOTTING;

ANIMALS; HEK293 CELLS; HUMANS; MALE; NEURALGIA; NEURONS, AFFERENT; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, OPIOID, MU; SPINAL CORD; SPINAL NERVES;

EID: 79960912227     PISSN: 10903801     EISSN: 15322149     Source Type: Journal    
DOI: 10.1016/j.ejpain.2010.11.018     Document Type: Article

References (39)

1. F. Benedetti, S. Vighetti, M. Amanzio, C. Casadio, A. Oliaro, and B. Bergamasco Dose-response relationship of opioids in nociceptive and neuropathic postoperative pain Pain 74 1998 205 211 (Pubitemid 28081607)
2. S.R. Chaplan, F.W. Bach, J.W. Pogrel, J.M. Chung, and T.L. Yaksh Quantitative assessment of tactile allodynia in the rat paw J Neurosci Methods 53 1994 55 63 (Pubitemid 24238751)
3. R.E. Coggeshall, S. Zhou, and S.M. Carlton Opioid receptors on peripheral sensory axons Brain Res 764 1997 126 132 (Pubitemid 27380647)
4. W.J. Dixon Efficient analysis of experimental observations Annu Rev Pharmacol Toxicol 20 1980 441 462
5. T. Fukuoka, A. Tokunaga, E. Kondo, K. Miki, T. Tachibana, and K. Noguchi Change in mRNAs for neuropeptides and the GABA(A) receptor in dorsal root ganglion neurons in a rat experimental neuropathic pain model Pain 78 1998 13 26 (Pubitemid 28451525)
6. T. Fukuoka, E. Kondo, Y. Dai, N. Hashimoto, and K. Noguchi Brain-derived neurotrophic factor increases in the uninjured dorsal root ganglion neurons in selective spinal nerve ligation model J Neurosci 21 2001 4891 4900 (Pubitemid 32565647)
7. T. Fukuoka, A. Tokunaga, T. Tachibana, Y. Dai, H. Yamanaka, and K. Noguchi VR1, but not P2X(3), increases in the spared L4 DRG in rats with L5 spinal nerve ligation Pain 99 2002 111 120 (Pubitemid 35247535)
8. I. Gilron, J.M. Bailey, D. Tu, R.R. Holden, D.F. Weaver, and R.L. Houlden Morphine, gabapentin, or their combination for neuropathic pain N Engl J Med 352 2005 1324 1334 (Pubitemid 40411499)
9. M.S. Gold, D. Weinreich, C.S. Kim, R. Wang, J. Treanor, and F. Porreca Redistribution of Na(V)1.8 in uninjured axons enables neuropathic pain J Neurosci 23 2003 158 166 (Pubitemid 36050415)
10. Y. Guan, L.M. Johanek, T.V. Hartke, B. Shim, Y.X. Tao, and M. Ringkamp Peripherally acting mu-opioid receptor agonist attenuates neuropathic pain in rats after L5 spinal nerve injury Pain 138 2008 318 329
11. X. Guan, X. Zhu, and Y.X. Tao Peripheral nerve injury up-regulates expression of interactor protein for cytohesin exchange factor 1 (IPCEF1) mRNA in rat dorsal root ganglion N-S Arch Pharmacol 380 2009 459 463
12. A.H. Hassan, A. Ableitner, C. Stein, and A. Herz Inflammation of the rat paw enhances axonal transport of opioid receptors in the sciatic nerve and increases their density in the inflamed tissue Neuroscience 55 1993 185 195 (Pubitemid 23194996)
13. M.P. Jankowski, J.J. Lawson, S.L. McIlwrath, K.K. Rau, C.E. Anderson, and K.M. Albers Sensitization of cutaneous nociceptors after nerve transection and regeneration: possible role of target-derived neurotrophic factor signaling J Neurosci 29 2009 1636 1647
14. N. Kabli, and C.M. Cahill Anti-allodynic effects of peripheral delta opioid receptors in neuropathic pain Pain 127 2007 84 93 (Pubitemid 44959432)
15. Y. Kawasaki, Z.Z. Xu, X. Wang, J.Y. Park, Z.Y. Zhuang, and P.H. Tan Distinct roles of matrix metalloproteases in the early- and late-phase development of neuropathic pain Nat Med 14 2008 331 336 (Pubitemid 351347915)
16. S.H. Kim, and J.M. Chung An experimental model for peripheral neuropathy produced by segmental spinal nerve ligation in the rat Pain 50 1992 355 363
17. T. Kohno, R.R. Ji, N. Ito, A.J. Allchorne, K. Befort, and L.A. Karchewski Peripheral axonal injury results in reduced mu opioid receptor pre- and post-synaptic action in the spinal cord Pain 117 2005 77 87 (Pubitemid 41764774)
18. T. Lewanowitsch, J.H. Miller, and R.J. Irvine Reversal of morphine, methadone and heroin induced effects in mice by naloxone methiodide Life Sci 78 2006 682 688 (Pubitemid 41821124)
19. H. Mansikka, C. Zhao, R.N. Sheth, I. Sora, G. Uhl, and S.N. Raja Nerve injury induces a tonic bilateral mu-opioid receptor-mediated inhibitory effect on mechanical allodynia in mice Anesthesiology 100 2004 912 921 (Pubitemid 38392579)
20. I. Obara, R. Przewlocki, and B. Przewlocka Local peripheral effects of mu-opioid receptor agonists in neuropathic pain in rats Neurosci Lett 360 2004 85 89 (Pubitemid 38471994)
21. I. Obara, W. Makuch, M. Spetea, J. Schutz, H. Schmidhammer, and R. Przewlocki Local peripheral antinociceptive effects of 14-O-methyloxymorphone derivatives in inflammatory and neuropathic pain in the rat Eur J Pharmacol 558 2007 60 67 (Pubitemid 46328870)
22. I. Obara, J.R. Parkitna, M. Korostynski, W. Makuch, D. Kaminska, and B. Przewlocka Local peripheral opioid effects and expression of opioid genes in the spinal cord and dorsal root ganglia in neuropathic and inflammatory pain Pain 141 2009 283 291
23. A.B. O'Connor Neuropathic pain: quality-of-life impact, costs and cost effectiveness of therapy Pharmacoeconomics 27 2009 95 112
24. G. Raivich, R. Hellweg, and G.W. Kreutzberg NGF receptor-mediated reduction in axonal NGF uptake and retrograde transport following sciatic nerve injury and during regeneration Neuron 7 1991 151 164
25. S.N. Raja, J.A. Haythornthwaite, M. Pappagallo, M.R. Clark, T.G. Travison, and S. Sabeen Opioids versus antidepressants in postherpetic neuralgia: a randomized, placebo-controlled trial Neurology 59 2002 1015 1021
26. M.H. Rashid, M. Inoue, K. Toda, and H. Ueda Loss of peripheral morphine analgesia contributes to the reduced effectiveness of systemic morphine in neuropathic pain J Pharmacol Exp Ther 309 2004 380 387 (Pubitemid 38393151)
27. B. Shim, M. Ringkamp, G.L. Lambrinos, T.V. Hartke, J.W. Griffin, and R.A. Meyer Activity-dependent slowing of conduction velocity in uninjured L4 C fibers increases after an L5 spinal nerve injury in the rat Pain 128 2007 40 51 (Pubitemid 46216596)
28. K. Shinoda, V.J. Hruby, and F. Porreca Antihyperalgesic effects of loperamide in a model of rat neuropathic pain are mediated by peripheral delta-opioid receptors Neurosci Lett 411 2007 143 146 (Pubitemid 44820680)
29. O.V. Singh, M. Yaster, J.T. Xu, Y. Guan, X. Guan, and A.M. Dharmarajan Proteome of synaptosome-associated proteins in spinal cord dorsal horn after peripheral nerve injury Proteomics 9 2009 1241 1253
30. L.C. Stanfa, A.F. Sullivan, and A.H. Dickenson Alterations in neuronal excitability and the potency of spinal mu, delta and kappa opioids after carrageenan-induced inflammation Pain 50 1992 345 354
31. C. Stein, J.D. Clark, U. Oh, M.R. Vasko, G.L. Wilcox, and A.C. Overland Peripheral mechanisms of pain and analgesia Brain Res Rev 60 2009 90 113
32. W. Truong, C. Cheng, Q.G. Xu, X.Q. Li, and D.W. Zochodne Mu opioid receptors and analgesia at the site of a peripheral nerve injury Ann Neurol 53 2003 366 375 (Pubitemid 36258640)
33. H. Uchida, L. Ma, and H. Ueda Epigenetic gene silencing underlies C-fiber dysfunctions in neuropathic pain J Neurosci 30 2010 4806 4814
34. G. Wu, M. Ringkamp, T.V. Hartke, B.B. Murinson, J.N. Campbell, and J.W. Griffin Early onset of spontaneous activity in uninjured C-fiber nociceptors after injury to neighboring nerve fibers J Neurosci 21 2001 RC140
35. G. Wu, M. Ringkamp, B.B. Murinson, E.M. Pogatzki, T.V. Hartke, and H.M. Weerahandi Degeneration of myelinated efferent fibers induces spontaneous activity in uninjured C-fiber afferents J Neurosci 22 2002 7746 7753 (Pubitemid 35386373)
36. C.L. Wu, S. Agarwal, P.K. Tella, B. Klick, M.R. Clark, and J.A. Haythornthwaite Morphine versus mexiletine for treatment of postamputation pain: a randomized, placebo-controlled, crossover trial Anesthesiology 109 2008 289 296
37. X. Zhang, L. Bao, T.J. Shi, G. Ju, R. Elde, and T. Hokfelt Down-regulation of mu-opioid receptors in rat and monkey dorsal root ganglion neurons and spinal cord after peripheral axotomy Neuroscience 82 1998 223 240
38. B. Zhang, F. Tao, W.J. Liaw, D.S. Bredt, R.A. Johns, and Y.X. Tao Effect of knock down of spinal cord PSD-93/chapsin-110 on persistent pain induced by complete Freund's adjuvant and peripheral nerve injury Pain 106 2003 187 196 (Pubitemid 37336543)
39. G. Zhang, H. Mohammad, B.D. Peper, S. Raja, S.P. Wilson, and S.M. Sweitzer Enhanced peripheral analgesia using virally mediated gene transfer of the mu-opioid receptor in mice Anesthesiology 108 2008 305 313 (Pubitemid 351156741)