Recurrent loss of the FHIT gene and its impact on lymphatic metastasis in early oral squamous cell carcinoma

Acta Oto-Laryngologica

Volumn 133, Issue 9, 2013, Pages 992-999

  Joo, Young Hoon ^a   Park, Sung Won ^a   Jung, Seung Hyun ^a   Lee, Yeon Soo ^a   Nam, In Chul ^a   Cho, Kwang Jae ^a   Park, Jun Ook ^a   Chung, Yeun Jun ^a   Kim, Min Sik ^a  

^a The Catholic University of Korea   (South Korea)

Author keywords

Comparative genomic hybridization; DNA copy number variations; Fragile histidine triad protein; Mouth neoplasms

Indexed keywords

FRAGILE HISTIDINE TRIAD PROTEIN;

ADULT; ARTICLE; CANCER PROGNOSIS; CHROMOSOME 3P; CHROMOSOME 5Q; CHROMOSOME 9Q; CLINICAL ARTICLE; COMPARATIVE GENOMIC HYBRIDIZATION; CONTROLLED STUDY; COPY NUMBER VARIATION; DISEASE SPECIFIC SURVIVAL; EARLY CANCER; FEMALE; GENE DOSAGE; GENE LOSS; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LYMPH NODE METASTASIS; LYMPH VESSEL METASTASIS; MALE; MOUTH SQUAMOUS CELL CARCINOMA; PERINEURAL INVASION; PRIORITY JOURNAL; TUMOR DIFFERENTIATION;

ACID ANHYDRIDE HYDROLASES; CARCINOMA, SQUAMOUS CELL; CHROMOSOME ABERRATIONS; DNA COPY NUMBER VARIATIONS; FEMALE; HUMANS; LYMPH NODES; LYMPHATIC METASTASIS; MALE; MIDDLE AGED; MOUTH NEOPLASMS; NECK; NEOPLASM PROTEINS; RETROSPECTIVE STUDIES;

EID: 84882326434     PISSN: 00016489     EISSN: 16512251     Source Type: Journal    
DOI: 10.3109/00016489.2013.795289     Document Type: Article

References (20)

1. Guttman D, Stern Y, Shpitzer T, Ulanovski D, Druzd T, Feinmesser R. Expression of MMP-9, TIMP-1, CD-34 and factor-8 as prognostic markers for squamous cell carcinoma of the tongue. Oral Oncol 2004;40:798-803
2. Rodrigo JP, Shah JP, Silver CE, Medina JE, Takes RP, Robbins KT, et al. Management of the clinically negative neck in early-stage head and neck cancers after transoral resection. Head Neck 2011;33:1210-19
3. Spiro RH, Huvos AG, Wong GY, Spiro JD, Gnecco CA, Strong EW. Predictive value of tumor thickness in squamous carcinoma confined to the tongue and floor of the mouth. Am J Surg 1986;152:345-50
4. O-charoenrat P, Rhys-Evans P, Eccles SA. Expression of vascular endothelial growth factor family members in head and neck squamous cell carcinoma correlates with lymph node metastasis. Cancer 2001;92:556-68
5. Weber RG, Scheer M, Born IA, Joos S, Cobbers JM, Hofele C, et al. Recurrent chromosomal imbalances detected in biopsy material from oral premalignant and malignant lesions by combined tissue microdissection, universal DNA amplification, and comparative genomic hybridization. Am J Pathol 1998;153:295-303
6. Vissers LE, Veltman JA, van Kessel AG, Brunner HG. Identification of disease genes by whole genome CGH arrays. Hum Mol Genet 2005;14:215-23
7. Liu CJ, Lin SC, Chen YJ, Chang KM, Chang KW. Arraycomparative genomic hybridization to detect genomewide changes in microdissected primary and metastatic oral squamous cell carcinomas. Mol Carcinog 2006;45:721-31
8. Sugahara K, Michikawa Y, Ishikawa K, Shoji Y, Iwakawa M, Shibahara T, et al. Combination effects of distinct cores in 11q13 amplification region on cervical lymph node metastasis of oral squamous cell carcinoma. Int J Oncol 2011;39:761-9
9. Jung SH, Lee A, Yim SH, Hu HJ, Choe C, Chung YJ. Simultaneous copy number gains of NUPR1 and ERBB2 predicting poor prognosis in early-stage breast cancer. BMC Cancer 2012;12:382
10. Kim TM, Yim SH, Shin SH, Xu HD, Jung YC, Park CK, et al. Clinical implication of recurrent copy number alterations in hepatocellular carcinoma and putative oncogenes in recurrent gains on 1q. Int J Cancer 2008;123:2808-15
11. Kim JH, Hu HJ, Yim SH, Bae JS, Kim SY, Chung YJ. CNVRuler: A copy number variation-based case-control association analysis tool. Bioinformatics 2012;28:1790-2
12. Kost-Alimova M, Imreh S. Modeling non-random deletions in cancer. Semin Cancer Biol 2007;17:19-30
13. Rosin MP, Lam WL, Poh C, Le ND, Li RJ, Zeng T, et al. 14 and 9p21 loss is a simple tool for predicting second oral malignancy at previously treated oral cancer sites. Cancer Res 2002;62:6447-50
14. Uchida K, Oga A, Nakao M, Mano T, Mihara M, Kawauchi S, et al. Loss of 3p26.3 is an independent prognostic factor in patients with oral squamous cell carcinoma. Oncol Rep 2011;26:463-9
15. Mori M, Mimori K, Shiraishi T, Alder H, Inoue H, Tanaka Y, et al. Altered expression of Fhit in carcinoma and precarcinomatous lesions of the esophagus. Cancer Res 2000;60:1177-82
16. Kuroki T, Trapasso F, Yendamuri S, Matsuyama A, Alder H, Mori M, et al. Allele loss and promoter hypermethylation of VHL, RAR-beta, RASSF1A, and FHIT tumor suppressor genes on chromosome 3p in esophageal squamous cell carcinoma. Cancer Res 2003;63:3724-8
17. Saldivar JC, Shibata H, Huebner K. Pathology and biology associated with the fragile FHIT gene and gene product. J Cell Biochem 2010;109:858-65
18. Matsuyama A, Croce CM, Huebner K. Common fragile genes. Eur J Histochem 2004;48:29-36
19. Huber O. Weiske J. b-catenin takes a HIT. Cell Cycle 2008; 7:1326-31
20. Hanahan D, Weinberg RA. Hallmarks of cancer: The next generation. Cell 2011;144:646-74