Biomarkers for sepsis: An unfinished journey

Clinical Chemistry and Laboratory Medicine

Volumn 51, Issue 6, 2013, Pages 1135-1138

  Clerico, Aldo ^b   Plebani, Mario ^a  

^a UNIVERSITY HOSPITAL OF PADOVA   (Italy)

^b SCUOLA SUPERIORE SANT ANNA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC AGENT; BIOLOGICAL MARKER; BRAIN NATRIURETIC PEPTIDE; PROCALCITONIN; TROPONIN I; TROPONIN T;

ACUTE KIDNEY FAILURE; ANTIBIOTIC THERAPY; DISEASE SEVERITY; EMERGENCY WARD; HEART DISEASE; HUMAN; INTENSIVE CARE UNIT; ITALY; MORTALITY; NEWBORN SEPSIS; PRIORITY JOURNAL; REVIEW; SEPTIC SHOCK; TURNAROUND TIME;

COMMUNICABLE DISEASES; EMERGENCY MEDICINE; EMERGENCY SERVICE, HOSPITAL; HUMANS;

EID: 84882304197     PISSN: 14346621     EISSN: 14374331     Source Type: Journal    
DOI: 10.1515/cclm-2013-0003     Document Type: Review

References (33)

1. Bone RC, Balk RA, Cerra FB, Dellinger RP, Fein AM, Knaus WA, et al. The ACCP/SCCM Consensus Conference Committee. Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. Chest 1992;101:1656-62.
2. Brun-Buisson C. The epidemiology of the systemic inflammatory response. Intensive Care Med 2000; S64-74.
3. Kumar A, Ellis P, Arabi Y, Roberts D, Light B, Parrillo JE, et al. Initiation of inappropriate antimicrobial therapy results in a fivefold reduction of survival in human septic shock. Chest 2009;136:1237-48.
4. Kibe S, Adams K, Barlow G. Diagnostic and prognostic biomarkers of sepsis in critical care. J Antimicrob Chemother 2011;66:ii33-40.
5. Marshall JC, Reinhart K; International Sepsis Forum. Biomarkers of sepsis. Crit Care Med 2009;37:2290-8.
6. Pierrakos C, Vincent JL. Sepsis biomarkers: a review. Crit Care 2010;14:R15.
7. Wong HR, Salisbury S, Xiao Q, Cvijanovich NZ, Hall M, Allen GL, et al. The pediatric sepsis biomarker risk model. Crit Care 2012;16:R174.
8. Xing K, Murthy S, Liles WC, Singh JM. Clinical utility of biomarkers of endothelial activation in sepsis - A systematic review. Crit Care 2012;16:R7.
9. Maeder M, Fehr T, Rickli H, Ammann P. Sepsis-associated myocardial dysfunction: diagnostic and prognostic impact of cardiac troponins and natriuretic peptides. Chest 2006;129:1349-66.
10. Rivers EP, McCord J, Otero R, Jacobsen G, Loomba M. Clinical utility of B-type natriuretic peptide in early severe sepsis and septic shock. J Intensive Care Med 2007;22:363-73.
11. Landesberg G, Gilon D, Meroz Y, Georgieva M, Levin PD, Goodman S, et al. Diastolic dysfunction and mortality in severe sepsis and septic shock. Eur Heart J 2012;33:895-903.
12. Di Somma S, Magrini L, Travaglino F, Lalle I, Fiotti N, Cervellin G, et al. Opinion paper on innovative approach of biomarkers for infectious diseases and sepsis management in the emergency department. Clin Chem Lab Med 2013;51:1167-75.
13. Lagabrielle JF, Tachet A, Boin V. Evaluation of two automated immunoassays for procalcitonin measurement: Kryptor (Brahms) and Vidas (BioM é rieux). Immuno-anal Biol Special 2008;23:245-50.
14. De Wolf HK, Klein Gunnewiek J, Berk Y, Van Den Ouweland J, De Metz M. Comparison of a new procalcitonin assay from Roche with the established method on the Brahms Kryptor. Clin Chem 2009;55:1043-4.
15. Hausfater P, Brochet C, Freund Y, Charles V, Bernard M. Procalcitonin measurement in routine emergency medicine practice: comparison between two immunoassays. Clin Chem Lab Med 2010;48:501-4.
16. Heyland DK, Johnson AP, Reynolds SC, Muscedere J. Procalcitonin for reduced antibiotic exposure in the critical care setting: a systematic review and an economic evaluation. Crit Care Med 2011;39:1792-9.
17. Kopterides P, Siempos II, Tsangaris I, Tsantes A, Armaganidis A. Procalcitonin-guided algorithms of antibiotic therapy in the intensive care unit: a systematic review and meta-analysis of randomized controlled trias. Crit Care Med 2010;38:2229-41.
18. Schuetz P, Chiappa V, Briel M, Greenwald JL. Procalcitonin algorithms for antibiotic therapy decisions: a systematic review of randomized controlled trials and recommendations for clinical algorithms. Arch Intern Med 2011;171:1322-31.
19. Vouloumanou EK, Plessa E, Karageorgopoulos DE, Mantadakis E, Falagas ME. Serum procalcitonin as a diagnostic marker for neonatal sepsis: a systematic review and meta-analysis. Intensive Care Med 2011;37:747-62.
20. Hochstadt A, Meroz Y, Landesberg G. Myocardial dysfunction in severe sepsis and septic shock: more questions than answers? J Cardiothorac Vasc Anesth 2011;25:526-35.
21. Vittorini S, Clerico A. Cardiovascular biomarkers: increasing impact of laboratory medicine in cardiology practice. Clin Chem Lab Med 2008;46:748-63.
22. Castillo JR, Zagler A, Carrillo-Jimenez R, Hennekens CH. Brain natriuretic peptide: a potential marker for mortality in septic shock. Int J Infect Dis 2004;8:271-4.
23. Turner KL, Moore LJ, Todd SR, Sucher JF, Jones SA, McKinley BA, et al. Identification of cardiac dysfunction in sepsis with B-type natriuretic peptide. J Am Coll Surg 2011;213:139-46.
24. Varpula M, Pulkki K, Karlsson S, Ruokonen E, Pettilä V; FINNSEPSIS Study Group. Predictive value of N-terminal pro-brain natriuretic peptide in severe sepsis and septic shock. Crit Care Med 2007;35:1277-83.
25. Post F, Weilemann LS, Messow CM, Sinning C, Munzel T. B-type natriuretic peptide as a marker for sepsis-induced myocardial depression in intensive care patients. Crit Care Med 2008;36:3030-7.
26. Makris K, Rizos D, Kafkas N, Haliassos A. Neurophil gelatinase-associated lipocalin as a new biomarker in laboratory medicine. Clin Chem Lab Med 2012;50:1519-32.
27. Clerico A, Galli C, Fortunato A, Ronco C. Neutrophil gelatinase- associated lipocalin (NGAL) as biomarker of acute kidney injury: a review of the laboratory characteristics and clinical evidences. Clin Chem Lab Med 2012;50:1505-17.
28. Lippi G, Plebani M. Neutrophil gelatinase-associated lipocalin (NGAL): the laboratory perspective. Clin Chem Lab Med 2012;50:1483-7.
29. Cervellin G, Di Somma S. Neutrophil gelatinase-associated lipocalin (NGAL): the clinician's perspective. Clin Chem Lab Med 2012;50:1489-93.
30. Angeletti S, Battistoni F, Fioravanti M, Bernardini S, Dicuonzo G. Procalcitonin and mid-regional pro-adrenomedullin test combination in sepsis diagnosis. Clin Chem Lab Med 2013;51:1059-67.
31. Bernstein LH, Rucinski J. Measurement of granulocyte maturation may improve the early diagnosis of the septic state. Clin Chem Lab Med 2011;49:2089-95.
32. Cimenti C, Erwa W, Herkner KR, Kasper DC, Müller W, Resch B. The predictive value of immature granulocyte count and immature myeloid information in the diagnosis of neonatal sepsis. Clin Chem Lab Med 2012;50:1429-32.
33. Gerrits JH, McLaughlin PM, Nienhuis BN, Smit JW, Loef B. Polymorphic mononuclear neutrophils CD64 index for diagnosis of sepsis in postoperative surgical patients and critically ill patients. Clin Chem Lab Med 2013;51:897-905.