Efficacy of the specific endothelin a receptor antagonist zibotentan (ZD4054) in colorectal cancer: A preclinical study

Molecular Cancer Therapeutics

Volumn 12, Issue 8, 2013, Pages 1556-1567

  Haque, Samer Ul ^a   Dashwood, Michael R ^b   Heetun, Mohammed ^a   Shiwen, Xu ^c   Farooqui, Noreen ^a   Ramesh, Bala ^a   Welch, Hazel ^a   Savage, Felicity J ^a   Ogunbiyi, Olagunju ^a   Abraham, David J ^c   Loizidou, Marilena ^a,b  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b ROYAL FREE HOSPITAL   (United Kingdom)

^c UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLO(DEXTRO TRYPTOPHYL DEXTRO ASPARTYLPROLYL DEXTRO VALYLLEUCYL); ENDOTHELIN 1; ENDOTHELIN A RECEPTOR; ENDOTHELIN B RECEPTOR; N (2,6 DIMETHYLPIPERIDINOCARBONYL) 4 METHYLLEUCYL DEXTRO (1 METHOXYCARBONYLTRYPTOPHANYL) DEXTRO NORLEUCINE; ZIBOTENTAN;

ARTICLE; AUTORADIOGRAPHY; CANCER GROWTH; CANCER LOCALIZATION; CELL MIGRATION; CELL PROLIFERATION; COLORECTAL CANCER; CONCENTRATION RESPONSE; CONTROLLED STUDY; DENSITOMETRY; DRUG EFFICACY; DRUG STRUCTURE; FIBROBLAST; HOMOGENATE; HUMAN; HUMAN CELL; IC 50; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; PRIORITY JOURNAL; RECEPTOR BINDING; RECEPTOR UPREGULATION; TISSUE SECTION;

ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; COLORECTAL NEOPLASMS; DRUG EVALUATION, PRECLINICAL; ENDOTHELIN-1; FIBROBLASTS; HUMANS; PROTEIN BINDING; PROTEIN TRANSPORT; PYRROLIDINES; RECEPTOR, ENDOTHELIN A; RECEPTOR, ENDOTHELIN B;

EID: 84882264904     PISSN: 15357163     EISSN: 15388514     Source Type: Journal    
DOI: 10.1158/1535-7163.MCT-12-0975     Document Type: Article

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