메뉴 건너뛰기




Volumn 7, Issue 9, 2013, Pages 729-741

Teratoma formation of human embryonic stem cells in three-dimensional perfusion culture bioreactors

Author keywords

3D tissue formation; Bioreactor; Differentiation; Embryoid body; Human embryonic stem cells; in vitro model; Teratoma

Indexed keywords

ASSAYS; BEHAVIORAL RESEARCH; BIOCONVERSION; BIOREACTORS; CELL CULTURE; CELL PROLIFERATION; HISTOLOGY; MAMMALS; TRANSCRIPTION; TUMORS;

EID: 84882249931     PISSN: 19326254     EISSN: 19327005     Source Type: Journal    
DOI: 10.1002/term.1467     Document Type: Article
Times cited : (32)

References (48)
  • 1
    • 34447295350 scopus 로고    scopus 로고
    • Characterization of human embryonic stem cell lines by the International Stem Cell Initiative
    • Adewumi O, Aflatoonian B, Ahrlund-Richter L, et al. 2007, Characterization of human embryonic stem cell lines by the International Stem Cell Initiative. Nat Biotechnol 25(7): 803-816.
    • (2007) Nat Biotechnol , vol.25 , Issue.7 , pp. 803-816
    • Adewumi, O.1    Aflatoonian, B.2    Ahrlund-Richter, L.3
  • 2
    • 49749094742 scopus 로고    scopus 로고
    • Is teratoma formation in stem cell research a characterization tool or a window to developmental biology?
    • Aleckovic M, Simon C. 2008; Is teratoma formation in stem cell research a characterization tool or a window to developmental biology? Reprod Biomed Online 17(2): 270-280.
    • (2008) Reprod Biomed Online , vol.17 , Issue.2 , pp. 270-280
    • Aleckovic, M.1    Simon, C.2
  • 3
    • 0034669082 scopus 로고    scopus 로고
    • Clonally derived human embryonic stem cell lines maintain pluripotency and proliferative potential for prolonged periods of culture
    • Amit M, Carpenter MK, Inokuma MS, et al. 2000; Clonally derived human embryonic stem cell lines maintain pluripotency and proliferative potential for prolonged periods of culture. Dev Biol 227(2): 271-278.
    • (2000) Dev Biol , vol.227 , Issue.2 , pp. 271-278
    • Amit, M.1    Carpenter, M.K.2    Inokuma, M.S.3
  • 4
    • 5144228375 scopus 로고    scopus 로고
    • The biology of desmin filaments: how do mutations affect their structure, assembly, and organisation?
    • Bar H, Strelkov SV, Sjoberg G, et al. 2004; The biology of desmin filaments: how do mutations affect their structure, assembly, and organisation? J Struct Biol 148(2): 137-152.
    • (2004) J Struct Biol , vol.148 , Issue.2 , pp. 137-152
    • Bar, H.1    Strelkov, S.V.2    Sjoberg, G.3
  • 5
    • 16444373230 scopus 로고    scopus 로고
    • Activin A maintains pluripotency of human embryonic stem cells in the absence of feeder layers
    • Beattie GM, Lopez AD, Bucay N, et al. 2005; Activin A maintains pluripotency of human embryonic stem cells in the absence of feeder layers. Stem Cells 23(4): 489-495.
    • (2005) Stem Cells , vol.23 , Issue.4 , pp. 489-495
    • Beattie, G.M.1    Lopez, A.D.2    Bucay, N.3
  • 6
    • 46449113364 scopus 로고    scopus 로고
    • The tumorigenicity of human embryonic stem cells
    • Blum B, Benvenisty N. 2008; The tumorigenicity of human embryonic stem cells. Adv Cancer Res 100: 133-158.
    • (2008) Adv Cancer Res , vol.100 , pp. 133-158
    • Blum, B.1    Benvenisty, N.2
  • 7
    • 33646574938 scopus 로고    scopus 로고
    • Growth of teratomas derived from human pluripotent stem cells is influenced by the graft site
    • Cooke MJ, Stojkovic M, Przyborski SA. 2006; Growth of teratomas derived from human pluripotent stem cells is influenced by the graft site. Stem Cells Dev 15(2): 254-259.
    • (2006) Stem Cells Dev , vol.15 , Issue.2 , pp. 254-259
    • Cooke, M.J.1    Stojkovic, M.2    Przyborski, S.A.3
  • 8
    • 0033665287 scopus 로고    scopus 로고
    • Embryoid bodies: an in vitro model of mouse embryogenesis
    • Desbaillets I, Ziegler U, Groscurth P, et al. 2000; Embryoid bodies: an in vitro model of mouse embryogenesis. Exp Physiol 85(6): 645-651.
    • (2000) Exp Physiol , vol.85 , Issue.6 , pp. 645-651
    • Desbaillets, I.1    Ziegler, U.2    Groscurth, P.3
  • 9
    • 0037383088 scopus 로고    scopus 로고
    • Fibroblast growth factors as regulators of central nervous system development and function
    • Dono R. 2003; Fibroblast growth factors as regulators of central nervous system development and function. Am J Physiol Regul Integr Comp Physiol 284(4): R867-R881.
    • (2003) Am J Physiol Regul Integr Comp Physiol , vol.284 , Issue.4
    • Dono, R.1
  • 10
    • 34547158898 scopus 로고    scopus 로고
    • Facilitated expansion of human embryonic stem cells by single-cell enzymatic dissociation
    • Ellerstrom C, Strehl R, Noaksson K, et al. 2007; Facilitated expansion of human embryonic stem cells by single-cell enzymatic dissociation. Stem Cells 25(7): 1690-1696.
    • (2007) Stem Cells , vol.25 , Issue.7 , pp. 1690-1696
    • Ellerstrom, C.1    Strehl, R.2    Noaksson, K.3
  • 11
    • 28744458859 scopus 로고    scopus 로고
    • Bioconductor: open software development for computational biology and bioinformatics
    • Gentleman RC, Carey VJ, Bates DM, et al. 2004; Bioconductor: open software development for computational biology and bioinformatics. Genome Biol 5(10): R80.
    • (2004) Genome Biol , vol.5 , Issue.10
    • Gentleman, R.C.1    Carey, V.J.2    Bates, D.M.3
  • 12
    • 77952382729 scopus 로고    scopus 로고
    • Dynamic 3D culture promotes spontaneous embryonic stem cell differentiation in vitro
    • Gerlach JC, Hout M, Edsbagge J, et al. 2010a; Dynamic 3D culture promotes spontaneous embryonic stem cell differentiation in vitro. Tissue Eng Part C Methods 16(1): 115-121.
    • (2010) Tissue Eng Part C Methods , vol.16 , Issue.1 , pp. 115-121
    • Gerlach, J.C.1    Hout, M.2    Edsbagge, J.3
  • 13
    • 77953808008 scopus 로고    scopus 로고
    • Interwoven four-compartment capillary membrane technology for three-dimensional perfusion with decentralized mass exchange to scale up embryonic stem cell culture
    • Gerlach JC, Lubberstedt M, Edsbagge J, et al. 2010b; Interwoven four-compartment capillary membrane technology for three-dimensional perfusion with decentralized mass exchange to scale up embryonic stem cell culture. Cells Tissues Organs 192(1): 39-49.
    • (2010) Cells Tissues Organs , vol.192 , Issue.1 , pp. 39-49
    • Gerlach, J.C.1    Lubberstedt, M.2    Edsbagge, J.3
  • 14
    • 0141478911 scopus 로고    scopus 로고
    • Use of primary human liver cells originating from discarded grafts in a bioreactor for liver support therapy and the prospects of culturing adult liver stem cells in bioreactors: a morphologic study
    • Gerlach JC, Mutig K, Sauer IM, et al. 2003; Use of primary human liver cells originating from discarded grafts in a bioreactor for liver support therapy and the prospects of culturing adult liver stem cells in bioreactors: a morphologic study. Transplantation 76(5): 781-786.
    • (2003) Transplantation , vol.76 , Issue.5 , pp. 781-786
    • Gerlach, J.C.1    Mutig, K.2    Sauer, I.M.3
  • 15
    • 4544326998 scopus 로고    scopus 로고
    • Organized development from human embryonic stem cells after injection into immunodeficient mice
    • Gertow K, Wolbank S, Rozell BR, et al. 2004; Organized development from human embryonic stem cells after injection into immunodeficient mice. Stem Cells Dev 13: 421-435.
    • (2004) Stem Cells Dev , vol.13 , pp. 421-435
    • Gertow, K.1    Wolbank, S.2    Rozell, B.R.3
  • 16
    • 38449114878 scopus 로고    scopus 로고
    • Nestin in central nervous system cells
    • Gilyarov AV. 2008; Nestin in central nervous system cells. Neurosci Behav Physiol 38(2): 165-169.
    • (2008) Neurosci Behav Physiol , vol.38 , Issue.2 , pp. 165-169
    • Gilyarov, A.V.1
  • 17
    • 54449091150 scopus 로고    scopus 로고
    • Preparation of autogenic human feeder cells for growth of human embryonic stem cells
    • units 1C
    • Gonzalez R, Loring JF, Snyder EY. 2008; Preparation of autogenic human feeder cells for growth of human embryonic stem cells. Curr Protoc Stem Cell Biol 1: units 1C 5.1-5.15.
    • (2008) Curr Protoc Stem Cell Biol , vol.1 , pp. 51-515
    • Gonzalez, R.1    Loring, J.F.2    Snyder, E.Y.3
  • 18
    • 0034107861 scopus 로고    scopus 로고
    • Role of fibroblast growth factor-2 in human brain: a focus on development
    • Gremo F, Presta M. 2000; Role of fibroblast growth factor-2 in human brain: a focus on development. Int J Dev Neurosci 18(2-3): 271-279.
    • (2000) Int J Dev Neurosci , vol.18 , Issue.2-3 , pp. 271-279
    • Gremo, F.1    Presta, M.2
  • 19
    • 2942591062 scopus 로고    scopus 로고
    • Derivation, characterization, and differentiation of human embryonic stem cells
    • Heins N, Englund MCO, Sjoblom C, et al. 2004; Derivation, characterization, and differentiation of human embryonic stem cells. Stem Cells 22(3): 367-376.
    • (2004) Stem Cells , vol.22 , Issue.3 , pp. 367-376
    • Heins, N.1    Englund, M.C.O.2    Sjoblom, C.3
  • 20
    • 1842479021 scopus 로고    scopus 로고
    • The 'brainy side' of human embryonic stem cells
    • Hornstein E, Benvenisty N. 2004; The 'brainy side' of human embryonic stem cells. J Neurosci Res 76(2): 169-173.
    • (2004) J Neurosci Res , vol.76 , Issue.2 , pp. 169-173
    • Hornstein, E.1    Benvenisty, N.2
  • 21
    • 34247598445 scopus 로고    scopus 로고
    • Neural stem cells, neural progenitors, and neurotrophic factors
    • Hsu YC, Lee DC, Chiu IM. 2007; Neural stem cells, neural progenitors, and neurotrophic factors. Cell Transplant 16(2): 133-150.
    • (2007) Cell Transplant , vol.16 , Issue.2 , pp. 133-150
    • Hsu, Y.C.1    Lee, D.C.2    Chiu, I.M.3
  • 22
    • 0034136393 scopus 로고    scopus 로고
    • Differentiation of human embryonic stem cells into embryoid bodies compromising the three embryonic germ layers
    • Itskovitz-Eldor J, Schuldiner M, Karsenti D, et al. 2000; Differentiation of human embryonic stem cells into embryoid bodies compromising the three embryonic germ layers. Mol Med 6(2): 88-95.
    • (2000) Mol Med , vol.6 , Issue.2 , pp. 88-95
    • Itskovitz-Eldor, J.1    Schuldiner, M.2    Karsenti, D.3
  • 23
    • 16244400050 scopus 로고    scopus 로고
    • TGFβ/activin/nodal signaling is necessary for the maintenance of pluripotency in human embryonic stem cells
    • James D, Levine AJ, Besser D, et al. 2005; TGFβ/activin/nodal signaling is necessary for the maintenance of pluripotency in human embryonic stem cells. Development 132(6): 1273-1282.
    • (2005) Development , vol.132 , Issue.6 , pp. 1273-1282
    • James, D.1    Levine, A.J.2    Besser, D.3
  • 24
    • 0037764082 scopus 로고    scopus 로고
    • Class III β-tubulin in human development and cancer
    • Katsetos CD, Herman MM, Mork SJ. 2003a; Class III β-tubulin in human development and cancer. Cell Motil Cytoskel 55(2): 77-96.
    • (2003) Cell Motil Cytoskel , vol.55 , Issue.2 , pp. 77-96
    • Katsetos, C.D.1    Herman, M.M.2    Mork, S.J.3
  • 25
    • 0345874561 scopus 로고    scopus 로고
    • Class III β-tubulin isotype: a key cytoskeletal protein at the crossroads of developmental neurobiology and tumor neuropathology
    • discussion, 867
    • Katsetos CD, Legido A, Perentes E, et al. 2003b; Class III β-tubulin isotype: a key cytoskeletal protein at the crossroads of developmental neurobiology and tumor neuropathology. J Child Neurol 18(12): 851-866; discussion, 867.
    • (2003) J Child Neurol , vol.18 , Issue.12 , pp. 851-866
    • Katsetos, C.D.1    Legido, A.2    Perentes, E.3
  • 26
    • 27244436044 scopus 로고    scopus 로고
    • Growth and differentiation of embryoid bodies derived from human embryonic stem cells: effect of glucose and basic fibroblast growth factor
    • Khoo ML, McQuade LR, Smith MS, et al. 2005; Growth and differentiation of embryoid bodies derived from human embryonic stem cells: effect of glucose and basic fibroblast growth factor. Biol Reprod 73(6): 1147-1156.
    • (2005) Biol Reprod , vol.73 , Issue.6 , pp. 1147-1156
    • Khoo, M.L.1    McQuade, L.R.2    Smith, M.S.3
  • 27
    • 8744290969 scopus 로고    scopus 로고
    • A novel, high-performance random array platform for quantitative gene expression profiling
    • Kuhn K, Baker SC, Chudin E, et al. 2004; A novel, high-performance random array platform for quantitative gene expression profiling. Genome Res 14(11): 2347-2356.
    • (2004) Genome Res , vol.14 , Issue.11 , pp. 2347-2356
    • Kuhn, K.1    Baker, S.C.2    Chudin, E.3
  • 28
    • 2942627777 scopus 로고    scopus 로고
    • Biological roles of alpha-fetoprotein during pregnancy and perinatal development
    • Mizejewski GJ. 2004; Biological roles of alpha-fetoprotein during pregnancy and perinatal development. Exp Biol Med (Maywood) 229(6): 439-463.
    • (2004) Exp Biol Med (Maywood) , vol.229 , Issue.6 , pp. 439-463
    • Mizejewski, G.J.1
  • 29
    • 40449141341 scopus 로고    scopus 로고
    • Marked differences in differentiation propensity among human embryonic stem cell lines
    • Osafune K, Caron L, Borowiak M, et al. 2008; Marked differences in differentiation propensity among human embryonic stem cell lines. Nat Biotechnol 26(3): 313-315.
    • (2008) Nat Biotechnol , vol.26 , Issue.3 , pp. 313-315
    • Osafune, K.1    Caron, L.2    Borowiak, M.3
  • 30
    • 77952238772 scopus 로고    scopus 로고
    • Spatial and temporal expression pattern of germ layer markers during human embryonic stem cell differentiation in embryoid bodies
    • Pekkanen-Mattila M, Pelto-Huikko M, Kujala V, et al. 2010; Spatial and temporal expression pattern of germ layer markers during human embryonic stem cell differentiation in embryoid bodies. Histochem Cell Biol 133(5): 595-606.
    • (2010) Histochem Cell Biol , vol.133 , Issue.5 , pp. 595-606
    • Pekkanen-Mattila, M.1    Pelto-Huikko, M.2    Kujala, V.3
  • 31
    • 79960012954 scopus 로고    scopus 로고
    • Modulation of mitochondrial biogenesis and bioenergetic metabolism upon in vitro and in vivo differentiation of human ES and iPS cells
    • Prigione A, Adjaye J. 2010; Modulation of mitochondrial biogenesis and bioenergetic metabolism upon in vitro and in vivo differentiation of human ES and iPS cells. Int J Dev Biol 54(11-12): 1729-1741.
    • (2010) Int J Dev Biol , vol.54 , Issue.11-12 , pp. 1729-1741
    • Prigione, A.1    Adjaye, J.2
  • 32
    • 77951002352 scopus 로고    scopus 로고
    • The senescence-related mitochondrial/oxidative stress pathway is repressed in human induced pluripotent stem cells
    • Prigione A, Fauler B, Lurz R, et al. 2010; The senescence-related mitochondrial/oxidative stress pathway is repressed in human induced pluripotent stem cells. Stem Cells 28(4): 721-733.
    • (2010) Stem Cells , vol.28 , Issue.4 , pp. 721-733
    • Prigione, A.1    Fauler, B.2    Lurz, R.3
  • 33
    • 27144522018 scopus 로고    scopus 로고
    • Differentiation of human embryonic stem cells after transplantation in immune-deficient mice
    • Przyborski SA. 2005; Differentiation of human embryonic stem cells after transplantation in immune-deficient mice. Stem Cells 23(9): 1242-1250.
    • (2005) Stem Cells , vol.23 , Issue.9 , pp. 1242-1250
    • Przyborski, S.A.1
  • 34
    • 0035203881 scopus 로고    scopus 로고
    • Neural progenitors from human embryonic stem cells
    • Reubinoff BE, Itsykson P, Turetsky T, et al. 2001; Neural progenitors from human embryonic stem cells. Nat Biotechnol 19(12): 1134-1140.
    • (2001) Nat Biotechnol , vol.19 , Issue.12 , pp. 1134-1140
    • Reubinoff, B.E.1    Itsykson, P.2    Turetsky, T.3
  • 35
    • 0037311919 scopus 로고    scopus 로고
    • TM4: a free, open-source system for microarray data management and analysis
    • Saeed AI, Sharov V, White J, et al. 2003; TM4: a free, open-source system for microarray data management and analysis. Biotechniques 34(2): 374-378.
    • (2003) Biotechniques , vol.34 , Issue.2 , pp. 374-378
    • Saeed, A.I.1    Sharov, V.2    White, J.3
  • 36
    • 45849093327 scopus 로고    scopus 로고
    • Differentiation of neural lineage cells from human pluripotent stem cells
    • Schwartz PH, Brick DJ, Stover AE, et al. 2008; Differentiation of neural lineage cells from human pluripotent stem cells, Methods 45(2): 142-158.
    • (2008) Methods , vol.45 , Issue.2 , pp. 142-158
    • Schwartz, P.H.1    Brick, D.J.2    Stover, A.E.3
  • 37
    • 33750218125 scopus 로고    scopus 로고
    • The classification, functions and clinical use of different isoforms of HCG
    • Stenman UH, Tiitinen A, Alfthan H, et al. 2006; The classification, functions and clinical use of different isoforms of HCG. Hum Reprod Update 12(6): 769-784.
    • (2006) Hum Reprod Update , vol.12 , Issue.6 , pp. 769-784
    • Stenman, U.H.1    Tiitinen, A.2    Alfthan, H.3
  • 38
    • 15544375987 scopus 로고    scopus 로고
    • An autogeneic feeder cell system that efficiently supports growth of undifferentiated human embryonic stem cells
    • Stojkovic P, Lako M, Stewart R, et al. 2005; An autogeneic feeder cell system that efficiently supports growth of undifferentiated human embryonic stem cells. Stem Cells 23(3): 306-314.
    • (2005) Stem Cells , vol.23 , Issue.3 , pp. 306-314
    • Stojkovic, P.1    Lako, M.2    Stewart, R.3
  • 39
    • 33845878586 scopus 로고    scopus 로고
    • Derivation and characterization of three new Spanish human embryonic stem cell lines (VAL-3 -4 -5) on human feeder and in serum-free conditions
    • Valbuena D, Galán A, Sánchez E, et al. 2006; Derivation and characterization of three new Spanish human embryonic stem cell lines (VAL-3 -4 -5) on human feeder and in serum-free conditions. Reprod Biomed Online 13(6): 875-886.
    • (2006) Reprod Biomed Online , vol.13 , Issue.6 , pp. 875-886
    • Valbuena, D.1    Galán, A.2    Sánchez, E.3
  • 40
    • 27644486756 scopus 로고    scopus 로고
    • Activin/Nodal and FGF pathways cooperate to maintain pluripotency of human embryonic stem cells
    • Vallier L, Alexander M, Pedersen RA. 2005; Activin/Nodal and FGF pathways cooperate to maintain pluripotency of human embryonic stem cells. J Cell Sci 118(pt 19): 4495-4509.
    • (2005) J Cell Sci , vol.118 , Issue.PART 19 , pp. 4495-4509
    • Vallier, L.1    Alexander, M.2    Pedersen, R.A.3
  • 41
    • 27644495875 scopus 로고    scopus 로고
    • Human embryonic stem cells: an in vitro model to study mechanisms controlling pluripotency in early mammalian development
    • Vallier L, Pedersen RA. 2005; Human embryonic stem cells: an in vitro model to study mechanisms controlling pluripotency in early mammalian development. Stem Cell Rev 1(2): 119-130.
    • (2005) Stem Cell Rev , vol.1 , Issue.2 , pp. 119-130
    • Vallier, L.1    Pedersen, R.A.2
  • 42
    • 33747614295 scopus 로고    scopus 로고
    • Activin A maintains self-renewal and regulates fibroblast growth factor, Wnt, and bone morphogenic protein pathways in human embryonic stem cells
    • Xiao L, Yuan X, Sharkis SJ. 2006; Activin A maintains self-renewal and regulates fibroblast growth factor, Wnt, and bone morphogenic protein pathways in human embryonic stem cells. Stem Cells 24(6): 1476-1486.
    • (2006) Stem Cells , vol.24 , Issue.6 , pp. 1476-1486
    • Xiao, L.1    Yuan, X.2    Sharkis, S.J.3
  • 43
    • 8644254420 scopus 로고    scopus 로고
    • Immortalized fibroblast-like cells derived from human embryonic stem cells support undifferentiated cell growth
    • Xu C, Jiang J, Sottile V, et al. 2004; Immortalized fibroblast-like cells derived from human embryonic stem cells support undifferentiated cell growth. Stem Cells 22(6): 972-980.
    • (2004) Stem Cells , vol.22 , Issue.6 , pp. 972-980
    • Xu, C.1    Jiang, J.2    Sottile, V.3
  • 44
    • 20144380595 scopus 로고    scopus 로고
    • Basic fibroblast growth factor supports undifferentiated human embryonic stem cell growth without conditioned medium
    • Xu C, Rosler E, Jiang J, et al. 2005a; Basic fibroblast growth factor supports undifferentiated human embryonic stem cell growth without conditioned medium. Stem Cells 23(3): 315-323.
    • (2005) Stem Cells , vol.23 , Issue.3 , pp. 315-323
    • Xu, C.1    Rosler, E.2    Jiang, J.3
  • 45
    • 1842853507 scopus 로고    scopus 로고
    • BMP4 initiates human embryonic stem cell differentiation to trophoblast
    • Xu RH, Chen X, Li DS, et al. 2002; BMP4 initiates human embryonic stem cell differentiation to trophoblast. Nat Biotechnol 20(12): 1261-1264.
    • (2002) Nat Biotechnol , vol.20 , Issue.12 , pp. 1261-1264
    • Xu, R.H.1    Chen, X.2    Li, D.S.3
  • 46
    • 18744375483 scopus 로고    scopus 로고
    • Basic FGF and suppression of BMP signaling sustain undifferentiated proliferation of human ES cells
    • Xu R-H, Peck RM, Li DS, et al. 2005b; Basic FGF and suppression of BMP signaling sustain undifferentiated proliferation of human ES cells. Nat Methods 2(3): 185-190.
    • (2005) Nat Methods , vol.2 , Issue.3 , pp. 185-190
    • Xu, R.-H.1    Peck, R.M.2    Li, D.S.3
  • 47
    • 27744511033 scopus 로고    scopus 로고
    • Efficient culture system for human embryonic stem cells using autologous human embryonic stem cell-derived feeder cells
    • Yoo SJ, Yoon BS, Kim JM, et al. 2005; Efficient culture system for human embryonic stem cells using autologous human embryonic stem cell-derived feeder cells. Exp Mol Med 37(5): 399-407.
    • (2005) Exp Mol Med , vol.37 , Issue.5 , pp. 399-407
    • Yoo, S.J.1    Yoon, B.S.2    Kim, J.M.3
  • 48
    • 79955441221 scopus 로고    scopus 로고
    • Scaling down of a clinical three-dimensional perfusion multicompartment hollow fiber liver bioreactor developed for extracorporeal liver support to an analytical scale device useful for hepatic pharmacological in vitro studies
    • Zeilinger K, Schreiter T, Darnell M, et al. 2011; Scaling down of a clinical three-dimensional perfusion multicompartment hollow fiber liver bioreactor developed for extracorporeal liver support to an analytical scale device useful for hepatic pharmacological in vitro studies. Tissue Eng Part C Methods 17(5): 549-556.
    • (2011) Tissue Eng Part C Methods , vol.17 , Issue.5 , pp. 549-556
    • Zeilinger, K.1    Schreiter, T.2    Darnell, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.