Galectins: New agonists of platelet activation

Biological Chemistry

Volumn 394, Issue 7, 2013, Pages 857-863

  Schattner, Mirta ^a   Rabinovich, Gabriel A ^b,c  

^a ACADEMIA NACIONAL DE MEDICINA   (Argentina)

^b INST DE BIOL Y MED EXPERIMENTAL   (Argentina)

^c UNIVERSIDAD DE BUENOS AIRES   (Argentina)

Author keywords

Atherosclerosis; Cancer; Galectins; Hemostasis; Inflammation; Platelets

Indexed keywords

GALECTIN 1; GALECTIN 8; THROMBOCYTE RECEPTOR; VON WILLEBRAND FACTOR;

BLOOD CLOTTING; CARBOXY TERMINAL SEQUENCE; CELL STIMULATION; HUMAN; MOLECULAR RECOGNITION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; REVIEW; SIGNAL TRANSDUCTION; THROMBOCYTE ACTIVATION; THROMBOCYTE ADHESION;

ANIMALS; BLOOD PLATELETS; GALECTINS; HEMOSTASIS; HUMANS; PLATELET ACTIVATION; PLATELET ADHESIVENESS;

EID: 84882242031     PISSN: 14316730     EISSN: 14374315     Source Type: Journal    
DOI: 10.1515/hsz-2013-0108     Document Type: Review

References (31)

1. Al-Ansari, S., Zeebregts, C.J., Slart, R.H., Peppelenbosch, M., and Tio, R.A. (2009). Galectins in atherosclerotic disease. Trends. Cardiovasc. Med. 19, 164-169.
2. Angiolillo DJ, Ueno M, Goto S. (2010). Basic principles of platelet biology and clinical implications. Circ. J. 74, 597-607.
3. Bidon-Wagner, N. and Le Pennec, J.P. (2004). Human galectin-8 isoforms and cancer. Glycoconj. J. 19, 557-563.
4. Cattaneo, V., Tribulatti, M.V., and Campetella, O. (2011). Galectin-8 tandem-repeat structure is essential for T-cell proliferation but not for co-stimulation. Biochem J. 434, 153-160.
5. Davicino, R.C., Eli ç abe, R.J., Di Genaro, M.S., and Rabinovich, G.A. (2011). Coupling pathogen recognition to innate immunity through glycan-dependent mechanisms. Int. Immunopharmacol. 11, 1457-1463.
6. Di Lella, S., Sundblad, V., Cerliani, J.P., Guardia, C.M., Estrin, D.A., Vasta, G.R., and Rabinovich, G.A. (2011). When galectins recognize glycans: from biochemistry to physiology and back again. Biochemistry 50, 7842-7857.
7. Dotsenko, O., Chaturvedi, N., Thom, S.A., Wright, A.R., Mayet, J., Shore, A., Schalkwijk, C., and Hughes, A.D. (2007). Platelet and leukocyte activation, atherosclerosis and inflammation in European and South Asian men. J. Thromb. Haemost. 5, 2036-2042.
8. Etulain, J.S.M. (2012). Current viewpoints on platelet contribution to inflammation. World J. Hematol. 1, 14-21.
9. Leslie, M. (2010). Cell biology. Beyond clotting: the powers of platelets. Science 328, 562-564.
10. Liu, F.T. and Rabinovich, G.A. (2005). Galectins as modulators of tumour progression. Nat. Rev. Cancer 5, 29-41.
11. Liu, F.T. and Rabinovich, G.A. (2010). Galectins: regulators of acute and chronic inflammation. Ann. N. Y. Acad. Sci. 1183, 158-182.
12. Luo, G.P., Ni, B., Yang, X., and Wu, Y.Z. (2012). von Willebrand factor: more than a regulator of hemostasis and thrombosis. Acta. Haematol. 128, 158-169.
13. Ma, Y.Q., Qin, J., and Plow, E.F. (2007). Platelet integrin alpha(IIb) beta(3): activation mechanisms. J. Thromb. Haemost. 5, 1345-1352.
14. May, A.E., Seizer, P., and Gawaz, M. (2008). Platelets: inflammatory firebugs of vascular walls. Arterioscler. Thromb. Vasc. Biol. 28, s5-10.
15. Morel, O., Toti, F., Hugel, B., Bakouboula, B., Camoin-Jau, L., Dignat-George, F., and Freyssinet, J.M. (2006). Procoagulant microparticles: disrupting the vascular homeostasis equation? Arterioscler. Thromb. Vasc. Biol. 26, 2594-2604.
16. Nurden, A.T., Nurden, P., Sanchez, M., Andia, I., and Anitua, E. (2008). Platelets and wound healing. Front. Biosci. 13, 3532-3548.
17. Ozaki, Y., Asazuma, N., Suzuki-Inoue, K., and Berndt, M.C. (2005). Platelet GPIb-IX-V-dependent signaling. J. Thromb. Haemost. 3, 1745-1751.
18. Pacienza, N., Pozner, R.G., Bianco, G.A., D'Atri, L.P., Croci, D.O., Negrotto, S., Malaver, E., Gómez, R.M., Rabinovich, G.A., and Schattner, M. (2008). The immunoregulatory glycan-binding protein galectin-1 triggers human platelet activation. Faseb. J. 22, 1113-1123.
19. Rabinovich, G.A. and Toscano, M.A. (2009). Turning'sweet' on immunity: galectin-glycan interactions in immune tolerance and inflammation. Nat. Rev. Immunol. 9, 338-352.
20. Rabinovich, G.A., Toscano, M.A., Jackson, S.S., and Vasta, G.R. (2007). Functions of cell surface galectin-glycoprotein lattices. Curr. Opin. Struct. Biol. 17, 513-520.
21. Rivera, J., Lozano, M.L., Navarro-Núñ ez, L., and Vicente, V. (2009). Platelet receptors and signaling in the dynamics of thrombus formation. Haematologica 94, 700-711.
22. Romaniuk, M.A., Tribulatti, M.V., Cattaneo, V., Lapponi, M.J., Molinas, F.C., Campetella, O., and Schattner, M. (2010). Human platelets express and are activated by galectin-8. Biochem J. 432, 535-547.
23. Romaniuk, M.A., Negrotto, S., Campetella, O., Rabinovich, G.A., and Schattner, M. (2011). Identification of galectins as novel regulators of platelet signaling and function. IUBMB Life 63, 521-527.
24. Romaniuk, M.A., Croci, D.O., Lapponi, M.J., Tribulatti, M.V., Negrotto, S., Poirier, F., Campetella, O., Rabinovich, G.A., and Schattner, M. (2012). Binding of galectin-1 to alphaIIbbeta(3) integrin triggers "outside- in" signals, stimulates platelet activation, and controls primary hemostasis. Faseb. J. 26, 2788-2798.
25. Saint-Lu, N., Oortwijn, B.D., Pegon, J.N., Odouard, S., Christophe, O.D., de Groot, P.G., Denis, C.V., and Lenting, P.J. (2012). Identification of galectin-1 and galectin-3 as novel partners for von Willebrand factor. Arterioscler. Thromb. Vasc. Biol. 32, 894-901.
26. Thijssen, V.L., Postel, R., Brandwijk, R.J., Dings, R.P., Nesmelova, I., Satijn, S., Verhofstad, N., Nakabeppu, Y., Baum, L.G., Bakkers, J., et al. (2006). Galectin-1 is essential in tumor angiogenesis and is a target for antiangiogenesis therapy. Proc. Natl. Acad. Sci. USA 103, 15975-15980.
27. Thijssen, V.L., Hulsmans, S., and Griffioen, A.W. (2008). The galectin profile of the endothelium: altered expression and localization in activated and tumor endothelial cells. Am. J. Pathol. 172, 545-553.
28. Torti, M., Festetics, E.T., Bertoni, A., Sinigaglia, F., and Balduini, C. (1999). Clustering of integrin alphaIIb-beta3 differently regulates tyrosine phosphorylation of pp72syk, PLCgamma2 and pp125FAK in concanavalin A-stimulated platelets. Thromb. Haemost. 81, 124-130.
29. Wagner, D.D. (2005). New links between inflammation and thrombosis. Arterioscler. Thromb. Vasc. Biol. 25, 1321-1324.
30. Yang, R.Y., Rabinovich, G.A., and Liu, F.T. (2008). Galectins: structure, function and therapeutic potential. Expert. Rev. Mol. Med. 10, e17.
31. Zappelli, C., van der Zwaan, C., Thijssen-Timmer, D.C., Mertens, K., and Meijer, A.B. (2012). Novel role for galectin-8 protein as mediator of coagulation factor V endocytosis by megakaryocytes. J. Biol. Chem. 287, 8327-8335.