Galectin-8 tandem-repeat structure is essential for T-cell proliferation but not for co-stimulation

Biochemical Journal

Volumn 434, Issue 1, 2011, Pages 153-160

  Cattaneo, Valentina ^a,b   Tribulatti, María V ^a,b   Campetella, Oscar ^a,b  

^a INSTITUTO DE INVESTIGACIONES BIOTECNOLÓGICAS   (Argentina)

^b Facultad de Ciencias Naturales e Instituto M Lillo   (Argentina)

Author keywords

Galectin alternative inhibitor; Glycan binding; Lattice formation; T cell activation

Indexed keywords

3 O BETA DEXTRO GALACTOPYRANOSYL DEXTRO ARABINOSE; GALECTIN 8; LACTOSE; PHYTOHEMAGGLUTININ; PROTEIN INHIBITOR; THIODIGALACTOSIDE; UNCLASSIFIED DRUG;

ADULT; ANIMAL CELL; ARTICLE; BLOOD GROUP B; CD4+ T LYMPHOCYTE; CELL DEATH; CHIMERA; ENZYME ACTIVITY; FEMALE; HUMAN; HUMAN CELL; IMMUNOSTIMULATION; LYMPHOCYTE PROLIFERATION; MALE; MOUSE; NONHUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; PROTEIN STRUCTURE; T LYMPHOCYTE ACTIVATION; TANDEM REPEAT;

ANIMALS; CELL LINE; CELL PROLIFERATION; GALECTINS; HUMANS; IMMUNITY, INNATE; LYMPHOCYTE ACTIVATION; MICE; MUTATION; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS; T-LYMPHOCYTES;

CHIMAERIFORMES;

EID: 79251546715     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20101691     Document Type: Article

References (37)

1. Elola, M. T., Wolfenstein-Todel, C., Troncoso, M. F., Vasta, G. R. and Rabinovich, G. A. (2007) Galectins: matricellular glycan-binding proteins linking cell adhesion, migration, and survival. Cell. Mol. Life Sci. 64, 1679-1700
2. Liu, F. T. and Rabinovich, G. A. (2010) Galectins: regulators of acute and chronic inflammation. Ann. N.Y. Acad. Sci. 1183, 158-182
3. Toscano, M. A., Ilarregui, J. M., Bianco, G. A., Campagna, L., Croci, D. O., Salatino, M. and Rabinovich, G. A. (2007) Dissecting the pathophysiologic role of endogenous lectins: glycan-binding proteins with cytokine-like activity? Cytokine Growth Factor Rev. 18, 57-71
4. Norling, L. V., Perretti, M. and Cooper, D. (2009) Endogenous galectins and the control of the host inflammatory response. J. Endocrinol. 201, 169-184
5. Rabinovich, G. A. and Toscano, M. A. (2009) Turning 'sweet' on immunity: galectin-glycan interactions in immune tolerance and inflammation. Nat. Rev. Immunol. 9, 338-352
6. Rabinovich, G. A., Toscano, M. A., Jackson, S. S. and Vasta, G. R. (2007) Functions of cell surface galectin-glycoprotein lattices. Curr. Opin. Struct. Biol. 17, 513-520
7. Su, Z. Z., Lin, J., Shen, R., Fisher, P. E., Goldstein, N. I. and Fisher, P. B. (1996) Surface-epitope masking and expression cloning identifies the human prostate carcinoma tumor antigen gene PCTA-1 a member of the galectin gene family. Proc. Natl. Acad. Sci. U.S.A. 93, 7252-7257
8. Hadari, Y. R., Arbel-Goren, R., Levy, Y., Amsterdam, A., Alon, R., Zakut, R. and Zick, Y. (2000) Galectin-8 binding to integrins inhibits cell adhesion and induces apoptosis. J. Cell Sci. 113, 2385-2397 (Pubitemid 30599342)
9. Bidon, N., Brichory, F., Hanash, S., Bourguet, P., Dazord, L. and Le Pennec, J. P. (2001) Two messenger RNAs and five isoforms for Po66-CBP, a galectin-8 homolog in a human lung carcinoma cell line. Gene 274, 253-262 (Pubitemid 32817143)
10. Camby, I., Belot, N., Rorive, S., Lefranc, F., Maurage, C. A., Lahm, H., Kaltner, H., Hadari, Y., Ruchoux, M. M., Brotchi, J. et al. (2001) Galectins are differentially expressed in supratentorial pilocytic astrocytomas, astrocytomas, anaplastic astrocytomas and glioblastomas, and significantly modulate tumor astrocyte migration. Brain Pathol. 11, 12-26
11. Henno, S., Brichory, F., Langanay, T., Desrues, B., Bidon, N., Delaval, P., Ramee, M. P., Dazord, L. and Caulet-Maugendre, S. (2002) Expression of Po66-CBP, a galectin-8, in different types of primary and secondary broncho-pulmonary tumors. Oncol. Rep. 9, 177-180
12. Wollina, U., Graefe, T., Feldrappe, S., Andre, S., Wasano, K., Kaltner, H., Zick, Y. and Gabius, H. J. (2002) Galectin fingerprinting by immuno- and lectin histochemistry in cutaneous lymphoma. J. Cancer Res. Clin. Oncol. 128, 103-110
13. Zick, Y., Eisenstein, M., Goren, R. A., Hadari, Y. R., Levy, Y. and Ronen, D. (2004) Role of galectin-8 as a modulator of cell adhesion and cell growth. Glycoconjugate J. 19, 517-526
14. Ideo, H., Seko, A., Ishizuka, I. and Yamashita, K. (2003) The N-terminal carbohydrate recognition domain of galectin-8 recognizes specific glycosphingolipids with high affinity. Glycobiology 13, 713-723 (Pubitemid 37337052)
15. Patnaik, S. K., Potvin, B., Carlsson, S., Sturm, D., Leffler, H. and Stanley, P. (2006) Complex N-glycans are the major ligands for galectin-1, -3, and -8 on Chinese hamster ovary cells. Glycobiology 16, 305-317
16. Carlsson, S., Oberg, C. T., Carlsson, M. C., Sundin, A., Nilsson, U. J., Smith, D., Cummings, R. D., Almkvist, J., Karlsson, A. and Leffler, H. (2007) Affinity of galectin-8 and its carbohydrate recognition domains for ligands in solution and at the cell surface. Glycobiology 17, 663-676
17. Stowell, S. R., Arthur, C. M., Slanina, K. A., Horton, J. R., Smith, D. F. and Cummings, R. D. (2008) Dimeric galectin-8 induces phosphatidylserine exposure in leukocytes through polylactosamine recognition by the carboxyl terminal domain. J. Biol. Chem. 283, 20547-20559
18. Levy, Y., Arbel-Goren, R., Hadari, Y. R., Eshhar, S., Ronen, D., Elhanany, E., Geiger, B. and Zick, Y. (2001) Galectin-8 functions as a matricellular modulator of cell adhesion. J. Biol. Chem. 276, 31285-31295
19. Levy, Y., Auslender, S., Eisenstein, M., Vidavski, R. R., Ronen, D., Bershadsky, A. D. and Zick, Y. (2006) It depends on the hinge: a structure-functional analysis of galectin-8, a tandem-repeat type lectin. Glycobiology 16, 463-476
20. high thymocyte subpopulation. Glycobiology 17, 1404-1412
21. Tribulatti, M. V., Cattaneo, V., Hellman, U., Mucci, J. and Campetella, O. (2009) Galectin-8 provides costimulatory and proliferative signals to T lymphocytes. J. Leukocyte Biol. 86, 371-380
22. Romaniuk, M. A., Tribulatti, M. V., Cattaneo, V., Lapponi, M. J., Molinas, F. C., Campetella, O. and Schattner, M. (2010) Human platelets express and are activated by galectin-8. Biochem. J. 432, 535-547
23. Stowell, S. R., Arthur, C. M., Mehta, P., Slanina, K. A., Blixt, O., Leffler, H., Smith, D. F. and Cummings, R. D. (2008) Galectin-1, -2, and -3 exhibit differential recognition of sialylated glycans and blood group antigens. J. Biol. Chem. 283, 10109-10123
24. Urbanek, R. A., Suchard, S. J., Steelman, G. B., Knappenberger, K. S., Sygowski, L. A., Veale, C. A. and Chapdelaine, M. J. (2001) Potent reversible inhibitors of the protein tyrosine phosphatase CD45. J. Med. Chem. 44, 1777-1793
25. Pace, K. E., Lee, C., Stewart, P. L. and Baum, L. G. (1999) Restricted receptor segregation into membrane microdomains occurs on human T cells during apoptosis induced by galectin-1. J. Immunol. 163, 3801-3811
26. Norambuena, A., Metz, C., Vicuna, L., Silva, A., Pardo, E., Oyanadel, C., Massardo, L., Gonzalez, A. and Soza, A. (2009) Galectin-8 induces apoptosis in Jurkat T cells by phosphatidic acid-mediated ERK1/2 activation supported by protein kinase A down-regulation. J. Biol. Chem. 284, 12670-12679
27. Lu, L. H., Nakagawa, R., Kashio, Y., Ito, A., Shoji, H., Nishi, N., Hirashima, M., Yamauchi, A. and Nakamura, T. (2007) Characterization of galectin-9-induced death of Jurkat T cells. J. Biochem. (Tokyo) 141, 157-172
28. Yamamoto, H., Nishi, N., Shoji, H., Itoh, A., Lu, L. H., Hirashima, M. and Nakamura, T. (2008) Induction of cell adhesion by galectin-8 and its target molecules in Jurkat T-cells. J. Biochem. 143, 311-324
29. Nishi, N., Shoji, H., Seki, M., Itoh, A., Miyanaka, H., Yuube, K., Hirashima, M. and Nakamura, T. (2003) Galectin-8 modulates neutrophil function via interaction with integrin αM. Glycobiology 13, 755-763
30. Earl, L. A., Bi, S. and Baum, L. G. (2011) Galectin multimerization and lattice formation is regulated by linker region structure. Glycobiology 21, 6-12
31. Brewer, C. F., Miceli, M. C. and Baum, L. G. (2002) Clusters, bundles, arrays and lattices: novel mechanisms for lectin-saccharide-mediated cellular interactions. Curr. Opin. Struct. Biol. 12, 616-623
32. Chen, I. J., Chen, H. L. and Demetriou, M. (2007) Lateral compartmentalization of T cell receptor versus CD45 by galectin-N-glycan binding and microfilaments coordinate basal and activation signaling. J. Biol. Chem. 282, 35361-35372
33. Bidon-Wagner, N. and Le Pennec, J. P. (2004) Human galectin-8 isoforms and cancer. Glycoconjugate J. 19, 557-563
34. Tribulatti, M. V., Mucci, J., Van Rooijen, N., Leguizamón, M. S. and Campetella, O. (2005) The trans-sialidase from Trypanosoma cruzi induces thrombocytopenia during acute Chagas' disease by reducing the platelet sialic acid contents. Infect. Immun. 73, 201-207
35. Boilard, E., Nigrovic, P. A., Larabee, K., Watts, G. F., Coblyn, J. S., Weinblatt, M. E., Massarotti, E. M., Remold-O'Donnell, E., Farndale, R. W., Ware, J. and Lee, D. M. (2010) Platelets amplify inflammation in arthritis via collagen-dependent microparticle production. Science 327, 580-583
36. Eshkar Sebban, L., Ronen, D., Levartovsky, D., Elkayam, O., Caspi, D., Aamar, S., Amital, H., Rubinow, A., Golan, I., Naor, D. and Zick, Y. (2007) The involvement of CD44 and its novel ligand galectin-8 in apoptotic regulation of autoimmune inflammation. J. Immunol. 179, 1225-1235
37. Carcamo, C., Pardo, E., Oyanadel, C., Bravo-Zehnder, M., Bull, P., Caceres, M., Martinez, J., Massardo, L., Jacobelli, S., Gonzalez, A. and Soza, A. (2006) Galectin-8 binds specific β1 integrins and induces polarized spreading highlighted by asymmetric lamellipodia in Jurkat T cells. Exp. Cell Res. 312, 374-386