Alcohol and cancer of the large intestine

Alcohol, Tobacco and Cancer

Volumn , Issue , 2006, Pages 63-77

  Seitz, Helmut K ^a   Pöschl, Gudrun ^a   Salaspuro, Mikko ^b  

^a Krankenhaus Salem   (Germany)

^b UNIVERSITY OF HELSINKI   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 84882105991     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1159/000095015     Document Type: Chapter

References (77)

1. Pöschl G, Seitz HK: Alcohol and cancer. Alcohol Alcohol 2004;39:155-165.
2. Breslow NE, Enstrom JE: Geographic correlations between mortality rates and alcohol, tobacco consumption in the United States. J Natl Cancer Inst 1974;53:631-639.
3. Kune GA, Vitetta L: Alcohol consumption and the etiology of colorectal cancer: a review of the scientific evidence from 1957 to 1991. Nutr Cancer 1992;18:97-111.
4. Giovannucci E, Rimm EB, Ascherio A, Stampfer MJ, Colditz GA, Willett WC: Alcohol, low-methionine - low folate diets, and risk of colon cancer in men. J Natl Cancer Inst 1995;87:265-273.
5. Goldbohm RA, van den Brandt PA, van't Veer P, Dorant E, Sturmans F, Hermus RJ: Prospective study on alcohol consumption and the risk of cancer of the colon and rectum in the Netherlands. Cancer Causes Control 1994;5:95-104.
6. Gapstur SM, Potter JD, Folsom AR: Alcohol consumption and colon and rectal cancer in postmenopausal women. Int J Epidemiol 1994;23:50-57.
7. Gerhardsson de Verdier M, Romelsjo A, Lundberg M: Alcohol and cancer of the colon and rectum. Eur J Cancer Prev 1993;2:401-408.
8. Meyer F, White E: Alcohol and nutrients in relation to colon cancer in middle-aged adults. Am J Epidemiol 1993;138:225-236.
9. Franceschi S, La Vecchia C: Alcohol and the risk of cancers of the stomach and colon-rectum. Dig Dis 1994;12:276-289.
10. Boutron MC, Faivre J, Dop MC, Quipourt V, Senesse P: Tobacco, alcohol, and colorectal tumors: a multistep process. Am J Epidemiol 1995;141:1038-1046.
11. Glynn SA, Albanes D, Pietinen P, Brown CC, Rautalahti M, Tangrea JA, Taylor PR, Virtamo J: Alcohol consumption and risk of colorectal cancer in a cohort of Finnish men. Cancer Causes Control 1996;7:214-223.
12. Yamada K, Araki S, Tamura M, Sakai I, Takahashi Y, Kashihara H, Kono S: Case-control study of colorectal carcinoma in situ and cancer in relation to cigarette smoking and alcohol use (Japan). Cancer Causes Control 1997;8:780-785.
13. Shimizu N, Nagata C, Shimizu H, Kametani M, Takeyama N, Ohnuma T, Matsushita S: Height, weight, and alcohol consumption in relation to the risk of colorectal cancer in Japan: a prospective study. Br J Cancer 2003;88:1038-1043.
14. Pedersen A, Johansen C, Gronbaek M: Relations between amount and type of alcohol and colon and rectal cancer in a Danish population based cohort study. Gut 2003;52:861-867.
15. Cho E, Smith-Warner SA, Ritz J, van den Brandt PA, Colditz GA, Folsom AR, Freudenheim JL, Giovannucci E, Goldbohm RA, Graham S, Holmberg L, Kim DH, Malila N, Miller AB, Pietinen P, Rohan TE, Sellers TA, Speizer FE, Willett WC, Wolk A, Hunter DJ: Alcohol intake and colorectal cancer: a pooled analysis of 8 cohort studies. Ann Intern Med 2004;140:603-613.
16. Seitz HK, Pöschl G, Simanowski UA: Alcohol and cancer. Recent Dev Alcohol 1998;14:67-95.
17. Kearney J, Giovannucci E, Rimm EB, Stampfer MJ, Colditz GA, Ascherio A, Bleday R, Willett WC: Diet, alcohol, and smoking and the occurrence of hyperplastic polyps of the colon and rectum (United States). Cancer Causes Control 1995;6:45-56.
18. Bardou M, Montembault S, Giraud V, Balian A, Borotto E, Houdayer C, Capron F, Chaput JC, Naveau S: Excessive alcohol consumption favours high risk polyp or colorectal cancer occurrence among patients with adenomas: a case control study. Gut 2002;50:38-42.
19. Le Marchand L, Wilkens LR, Hankin JH, Kolonel LN, Lyu LC: Independent and joint effects of family history and lifestyle on colorectal cancer risk: implications for prevention. Cancer Epidemiol Biomarkers Prev 1999;8:45-851.
20. Scheppach W, Bingham S, Boutron-Ruault MC, Gerhardsson de Verdier M, Moreno V, Nagengast FM, Reifen R, Riboli E, Seitz HK, Wahrendorf J: WHO consensus statement on the role of nutrition in colorectal cancer. Eur J Cancer Prev 1999;8:57-62.
21. Larsson SC, Giovannucci E, Wolk A: Vitamin B6 intake, alcohol consumption, and colorectal cancer: a longitudinal population-based cohort of women. Gastroenterology 2005;128:1830-1837.
22. Su LJ, Arab L: Alcohol consumption and risk of colon cancer: evidence from the national health and nutrition examination survey I epidemiologic follow-up study. Nutr Cancer 2004;50:111-119.
23. Ketcham AS, Wexler H, Mantel N: Effects of alcohol in mouse neoplasia. Cancer Res 23:703-709.
24. Howarth AE, Pihl E: High-fat diet promotes and causes distal shift of experimental rat colonic cancer - beer and alcohol do not. Nutr Cancer 1984;6:229-235.
25. Nelson RL, Samelson SL: Neither dietary ethanol nor beer augments experimental colon carcinogenesis in rats. Dis Colon Rectum 1985;28:460-462.
26. Seitz HK, Czygan P, Waldherr R, Veith S, Raedsch R, Kassmodel H, Kommerell B: Enhancement of 1,2-dimethylhydrazine-induced rectal carcinogenesis following chronic ethanol consumption in the rat. Gastroenterology 1984;86:886-891.
27. McGarrity TJ, Via EA, Colony PC: Qualitative and quantitative changes in sialomucins during 1,2-dimethylhydrazine-induced colon carcinogenesis in the rat. J Natl Cancer Inst 1987;79: 1375-1382.
28. Hamilton SR, Sohn OS, Fiala ES: Effects of timing and quantity of chronic dietary ethanol consumption on azoxymethane-induced colonic carcinogenesis and azoxymethane metabolism in Fischer 344 rats. Cancer Res 1987;47:4305-4311.
29. Hamilton SR, Hyland J, McAvinchey D, Chaudhry Y, Hartka L, Kim HT, Cichon P, Floyd J, Turjman N, Kessie G, Nair PP, Dick J: Effects of chronic dietary beer and ethanol consumption on experimental colonic carcinogenesis by azoxymethane in rats. Cancer Res 1987;47: 1551-1559.
30. Garzon FT, Simanowski UA, Berger MR, Schmahl D, Kommerell B, Seitz HK: Acetoxymethylmethylnitrosamine (AMMN) induced colorectal carcinogenesis is stimulated by chronic alcohol consumption. Alcohol Alcohol Suppl 1987;1:501-502.
31. Seitz HK, Simanowski UA, Garzon FT, Rideout JM, Peters TJ, Koch A, Berger MR, Einecke H, Maiwald M: Possible role of acetaldehyde in ethanol-related rectal cocarcinogenesis in the rat. Gastroenterology 1990;98:406-413.
32. Helander A, Lindahl-Kiessling K: Increased frequency of acetaldehyde-induced sister-chromatide exchanges in human lymphocytes treated with an aldehyde dehydrogenase inhibitor. Mutat Res 1991;264:103-107.
33. Anonymous: Acetaldehyde. IARC Monogr Eval Carcinog Risk Chem Hum 1985;36.
34. Seitz HK, Oneta CM: Gastrointestinal alcohol dehydrogenases. Nutr Rev 1998;56:52-60.
35. IARC, Acetaldehyde IARC Monographs on the evaluation of the carcinogenic risk to humans. Reevaluation of some organic chemicals, hydrazine and hydrogen peroxides. Lyon, International Agency for Research on Cancer 1999, vol 71, pp 319-335.
36. Dellarco VL: A mutagenicity assessment of acetaldehyde. Mutat Res 1988;195:1-20.
37. Obe G, Jonas R, Schmidt S: Metabolism of ethanol in vitro produces a compound which induces sister-chromatid exchanges in human peripheral lymphocytes in vitro: acetaldehyde not ethanol is mutagenic. Mutat Res 1986;174:47-51.
38. Seitz HK, Matsuzaki S, Yokoyama A, Homann N, Väkeväinen S, Wang XD: Alcohol and cancer. Alcohol Clin Exp Res 2001;25:137-143.
39. Simanowski UA, Suter P, Russel RM, Heller M, Waldherr R, Ward R, Peters TJ, Smith D, Seitz HK: Enhancement of ethanol induced rectal mucosal hyperregeneration with age in F244 rats. Gut 1994;35:1102-1106.
40. Homann N, Kärkkäinen P, Koivisto T, Nosova T, Jokelainen K, Salaspuro M: Effects of acetaldehyde on cell regeneration and differentiation of the upper gastrointestinal tract mucosa. J Natl Cancer Inst 1997;89:1692-1697.
41. Simanowski UA, Suter PM, Stickel F, Maier H, Waldherr R, Smith D, Russell RM, Seitz HK: Esophageal epithelial hyperregeneration following chronic ethanol ingestion: effect of age and salivary gland function. J Natl Cancer Inst 1993;85:2030-2033.
42. Espina N, Lima V, Lieber CS, Garro AJ: In vitro and in vivo inhibitory effect of ethanol and acetaldehyde on O6-methylguanine transferase. Carcionogenesis 1988;9:761-766.
43. Feron VJ, Kruysee A, Wouterson RA: Respiratory tract tumours in hamsters exposed to acetaldehyde vapour alone or simultaneously to benzo(a)pyrene or diethylnitrosamine. Eur J Cancer Clin Oncol 1982;18:13-31.
44. Fang JL, Vaca CE: Development of a 32P-postlabeling method for the analysis of adducts arising through the reaction of acetaldehyde with 2'-deoxyguanosine-3'-monophosphate and DNA. Carcinogenesis 1995;16:2177-2185.
45. Fang JL, Vaca CE: Detection of DNA adducts of acetaldehyde in peripheral white blood cells of alcohol abusers. Carcinogenesis 1997;18:627-632.
46. Matsuda T, Terashima I, Matsumoto Y, Yabushita H, Matsui S, Shibutani S: Effective utilization of N2-ethyl-2'-deoxyguanosine triphosphate during DNA synthesis catalyzed by mammalian replicative DNA polymerases. Biochemistry 1999;38:929-935.
47. Brooks PJ, Thiruvathu JA: DNA adducts from acetaldehyde: implications for alcohol-related carcinogenesis. Alcohol 2005;35:187-193.
48. Salaspuro M: Acetaldehyde, microbes, and cancer of the digestive tract. Crit Rev Clin Lab Sci 2003;40:183-208.
49. Yokoyama A, Muramatsu T, Ohmori T, Yokoyama T, Okuyama K, Takahashi H, Hasegawa Y, Higuchi S, Maruyama K, Shirakura K, Ishii H: Alcohol-related cancers and aldehydrogenase-2 in Japanese alcoholics. Carcinogenesis 1998;19:1383-1387.
50. Bosron WF, Li TK: Genetic polymorphism of human liver alcohol and aldehyde dehydrogenase, and their relationship to alcohol metabolism and alcoholism. Hepatology 1986;6:502-510.
51. Borras E, Coutelle C, Rosell A, Fernandez-Muixi F, Broch M, Crosas B, Hjelmqvist L, Lorenzo A, Gutierrez C, Santos M, Szczepanek M, Heilig, M. Quattrocchi P, Farres J, Vidal F, Richart C, Mach T, Bogdal J, Jornvall H, Seitz HK, Couzigou P, Parex X: Genetic polymorphism of alcohol dehydrogenase in Europeans: the ADH1B*2 allele decreases the risk for alcoholism and is associated with ADH1C*1. Hepatology 2000;31:984-989.
52. Chao YC, Young TH, Thang HS, Hsu CT: Alcoholism and alcoholic organ damage and genetic polymorphisms of alcohol metabolizing enzymes in Chinese patients. Hepatology 1997;25: 112-117.
53. Visapää JP, Götte K, Benesova, Li JJ, Homann N, Conradt C, Inoue H, Tisch M, Hörmann K, Väkeväinen S, Salaspuro M, Seitz HK: Increased cancer risk in heavy drinkers with the alcohol dehydrogenasse 3*1-Allel possibly due to salivary acetaldehyde. Gut 2004;53:871-876.
54. Homann N, Stickel F, König IR, Jacobs A, Junghanns K, Benesova M, Schuppan D, Himsel S, Zuber-Jerger I, Hellerbrand C, Ludwig D, Caselmann WH, Seitz HK: Alcohol dehydrogenase 1C*1 allele is a genetic marker for alcohol-associated cancer in heavy drinkers. Int J Cancer 2005;118:1998-2002.
55. Marks M, Benesova M, Stickel F, Büchler MW, Seitz HK: Alcohol intake, ADH1C genotype and colorectal cancer. Alcohol Alcohol 2005;40:i44-i45.
56. Brozinski S, Fami K, Grosberg JJ: Alcohol ingestion-induced changes in the human rectal mucosa: light and electronmicroscopic studies. Dis Colon Rectum 1979;21:329-335.
57. Seitz HK, Simanowski UA, Garzon FT, Peters TJ: Alcohol and cancer (Letter to the Editor). Hepatology 1987;7:616.
58. Simanowski UA, Seitz HK, Baier B, Kommerell B, Schmidt-Gayk H, Wright NA: Chronic ethanol consumption selectively stimulates rectal cell proliferation in the rat. Gut 1986;27:278-282.
59. Simanowski UA, Homann N, Knühl M, Arce C, Waldherr R, Conradt C, Bosch FX, Seitz HK: Increased rectal cell proliferation following alcohol abuse. Gut 2001;49:418-422.
60. Jokelainen K, Roine R, Väänänen H, Salaspuro M: In vitro acetaldehyde formation by human colonic bacteria. Gut 1994;35:1271-1274.
61. Jokelainen K, Siitonen A, Jousimies-Somer H: In vitro alcohol dehydrogenase-mediated acetaldehyde production by aerobic bacteria representing the normal colonic flora in man. Alcohol Clin Exp Res 1996;20:967-972.
62. Salaspuro V, Nyfors S, Heine R, Siitonen A. Salaspuro M, Jousimies-Somer H: Ethanol oxidation and acetaldehyde production in vitro by human intestinal strains of Eschericia coli under aerobic, microaerobic, and anaerobic conditions. Scand J Gastroenterol 1999;34:967-973.
63. Jokelainen K, Matysiak-Budnik T, Mäkisalo H, Höckerstedt K, Salaspuro M: High intracolonic acetaldehyde values produced by a bacteriocolonic pathway for ethanol oxidation in piglets. Gut 1996;39:100-104.
64. Jokelainen K, Nosova T, Koivisto T, Väkeväinen S, Jousimies-Somer H, Heine R, Salaspuro M: Inhibition of bacteriocolonic pathway for ethanol oxidation by ciprofloxacin in rats. Life Sci 1997;61:1755-1762.
65. Tillonen J, Homann N, Rautio M, Jousimies-Somer H, Salaspuro M: Ciprofloxacin decreases the rate of ethanol elimination in humans. Gut 1999b;44:347-352.
66. Shimizu M, Lasker JM, Tsutsumi M, Lieber CS: Immunohistochemical localization of ethanol inducible cytochrome P4502E1 in rat alimentary tract. Gastroenterology 1990;93:1044-1050.
67. Baumgarten G, Waldherr R, Stickel F, Simanowski UA, Ingelmann-Sundberg M, Seitz HK: Enhanced expression of cytochrome P450 2E1 in the oropharyngeal mucosa in alcoholics with cancer. Annual meeting international society of biomedical researchers, alcoholism. Washington DC, June 22-27, 1996.
68. Seitz HK, Osswald B: Effect of ethanol on procarcinogen activation; in Watson RR (ed): Alcohol and Cancer. Boca Raton, Ann Arbor, London, Tokyo, CRC Press 1992, pp 55-72.
69. Gouillon Z, Lucas D, Li JJ, Hagbjork AL, French BA, Fu P, Fang C, Ingelman-Sundberg M, Donohue TM, French SW: Inhibition of ethanol-induced liver disease in the intragastric feeding rat model by chlormethiazole. Proc Soc Exp Biol Med 2000;224:302-308.
70. Frank A, Seitz HK, Bartsch H, Frank N, Nair J: Immunohistochemical detection of 1,N6-ethenodeoxyadenosine in nuclei of human liver affected by diseases predisposing to hepatocarcino-genesis. Carcinogenesis 2004;25:1027-1031.
71. Oneta CM, Lieber CS, Li JJ, Ruttimann S, Schmid B, Lattmann J, Rosman AS, Seitz HK: Dynamics of cytochrome P4502E1 activity in man: induction by ethanol and disappearance during withdrawal phase. J Hepatol 2002;36:47-52.
72. Sohn OA, Fiala ES, Puz C: Enhancement of rat liver microsomal metabolism of azoxymethane to methylazoxymethanol by chronic ethanol administration: similarity to the microsomal metabolism of N-nitrosomethylamine. Cancer Res 1987;47:3123-3129.
73. Vincon P, Wunderer J, Simanowski UA, Koll M, Preedy VR, Peters TJ, Werner J, Waldherr R, Seitz HK: Effect of ethanol and vitamin E on cell regeneration and BCL-2 expression in the colorectal mucosa of rats. Alcohol Clin Exp Res 2003;27:100-106.
74. Stickel F, Herold C, Seitz HK, Schuppan D: Alcohol and methyl transfer: implications for alcohol-related hepatocarcinogenesis; in Ali S, Friedman SL, Mann DA (eds): Liver Diseases: Biochemical Mechanisms and New Therapeutic Insights. New Delhi, Oxford and IBH Publ Co PRT.Ltd., 2005, pp 57-70.
75. Homann N, Tillonen J, Salaspuro M: Heavy alcohol intake leads to local colonic folate deficiency in rats: evidence of microbal acetaldehyde production from ethanol is the pathogenic substance. Int J Cancer 2000;86:169-173.
76. Choi SW, Stickel F, Baik W, Kim YI, Seitz HK, Mason JC: Chronic alcohol consumption induces genomic, but not p53-specific DNA hypomethylation in the colon of the rat. J Nutr 1999;129: 1945-1950.
77. Seitz HK: Alcohol and retinoid metabolism (Editorial). Gut 2000;47:748-750.