Alcoholism and alcoholic organ damage and genetic polymorphisms of alcohol metabolizing enzymes in chinese patients

Hepatology

Volumn 25, Issue 1, 1997, Pages 112-117

  Chao, You Chen ^a   Young, Tong Ho ^a   Tang, Hung Shang ^a   Hsu, Chung Te ^a  

^a TRI SERVICE GENERAL HOSPITAL   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

ALCOHOL DEHYDROGENASE; ALDEHYDE DEHYDROGENASE; CYTOCHROME P450; LIVER ENZYME;

ACUTE PANCREATITIS; ADULT; ALCOHOL CONSUMPTION; ALCOHOL METABOLISM; ALCOHOLISM; ALLELE; ARTICLE; CHINESE; CONTROLLED STUDY; FEMALE; GENE FREQUENCY; GENETIC POLYMORPHISM; HUMAN; LIVER CIRRHOSIS; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL;

EID: 0031012252     PISSN: 02709139     EISSN: None     Source Type: Journal    
DOI: 10.1002/hep.510250121     Document Type: Article

References (25)

1. Schuckit MA. Alcohol and alcoholism. In: Braunwald E, Isselbacher KJ, eds. Harrison's Principles of Internal Medicine. Ed 13. New York: McGrawHill, 1995:2420-2425.
2. Lieber CS. Alcohol and the liver: 1994 update. HEPATOLOGY 1994;106: 1085-1105.
3. Bosron WF, Li T-K. Genetic polymorphism of human liver alcohol and aldehyde dehydrogenase, and their relationship to alcohol metabolism and alcoholism. HEPATOLOGY 1986;6:502-510.
4. Bosron WF, Ehrig T, Li T-K. Genetic factors in alcohol metabolism and alcoholism. Semin Liver Dis 1993;13:126-135.
5. Goedde HW, Agarwal DP. Acetaldehyde metabolism: genetic variation and physiological implications. In: Goedde HW, Agarwal DP, eds. Alcoholism: Biomedical and Genetic Aspects. Elmsford: Pergamon Press, 1989:21-56.
6. Smith M. Genetics of human alcohol and aldehyde dehydrogenases. Adv Hum Genet 1986;15:249-290.
7. Yoshida A, Hsu LC, Yasunami M. Genetics of human alcohol-metabolizing enzymes. Prog Nucleic Acid Res Mol Biol 1991;40:255-287.
8. Goedde HW, Agarwal DP, Fritze G, Meier-Tackmann D, Singh S, Beckmann G, Bhatia K, et al. Distribution of ADH2 and ALDH2 genotypes in different populations. Hum Genet 1992;88:344-346.
9. Harada S, Misawa S, Agarwal DP, Goedde HW. Liver aldehyde dehydrogenase in Japanese: Isoenzyme variation and its possible role in alcohol intoxication. Am J Hum Genet 1980;32:8-15.
10. Enomoto N, Takase S, Takada N, Takada A. Alcoholic liver disease in heterozygotes of mutant and normal aldehyde dehydrogenase-2 genes. HEPATOLOGY 1991;13:1071-1075.
11. Thomasson HR, Edenberg HJ, Crabb DW, Mai X-L, Jerome RE, Li T-K, Wang S-P, et al. Alcohol and aldehyde dehydrogenase genotypes and alcoholism in Chinese men. Am J Hum Genet 1991;48:677-681.
12. Chao Y-C, Young T-H, Chang W-K, Tang H-S, Hsu C-T. An investigation of whether polymorphisms of cytochromeP4502E1 are genetic markers of susceptibility to alcoholic end-stage organ damage in a Chinese population. HEPATOLOGY 1995;22:1409-1414.
13. Stephens EA, Taylor JA, Kaplan N, Yang CH, Hsieh LL, Lucier GW, Bell DA. Ethnic variation in the CYP2E1 gene: polymorphism analysis of 695 African-Americans, European-Americans and Taiwanese. Pharmacogenetics 1994;4:185-192.
14. Kato S, Shields PG, Caporaso NE, Hoover RN, Trump BF, Sugimura H, Weston A, et al. Cytochrome P450IIE1 polymorphisms, racial variation and lung cancer risk. Cancer Res 1993;52:6712-6715.
15. Chao Y-C, Liou S-R, Chung Y-Y, Tang H-S, Hsu C-T, Li T-K, Yin S-J. Polymorphism of alcohol and aldehyde dehydrogenase genes and alcoholic cirrhosis in Chinese patients. HEPATOLOGY 1994;19:360-366.
16. Maezawa Y, Yamauchi M, Toda G. Association between restriction fragment length polymorphism of the human cytochrome P450IIE1 gene and susceptibility to alcoholic liver cirrhosis. Am J Gastroenterol 1994;89:561-565.
17. Tsutsumi M, Takada A, Wang J-S. Genetic polymorphisms of cytochrome P4502E1 related to the development of alcoholic liver disease. Gastroenterology 1994;107:1430-1435.
18. Yamauchi M, Maezawa Y, Mizuhara Y, Ohata M, Hirakawa J, Nakajima H, Toda G. Polymorphisms in alcohol metabolizing enzyme genes and alcoholic cirrhosis in Japanese patients: A multivariate analysis. HEPATOLOGY 1995;22:1136-1142.
19. Larzul D, Guige F, Sninsky JJ, Mack DH, Brechot C, Guesdon JL. Detection of hepatitis B virus sequences in serum by using in vitro enzymatic amplification. J Virological Methods 1988;20:227-237.
20. Pugh RNH, Murray-Lyon IM, Dawson JL, Pietroni MC, Williams R. Transection of the oesophagus for bleeding oesophageal varices. Br J Surg 1973; 60:646-649.
21. Groppi A, Begueret J, Iron A. Improved methods for genotype determination of human alcohol dehydrogenase (ADH) at ADH2 and ADH3 loci by using polymerase chain reaction-directed mutagenesis. Clin Chem 1990; 36:1765-1768.
22. Chao Y-C, Wang M-F, Tang H-S, Hsu C-T, Yin S-J. Genotyping of alcohol dehydrogenase at the ADH2 and ADH3 loci by using a polymerase chain reaction and restriction-fragment-length polymorphism in Chinese alcoholic cirrhotics and non-alcoholics. Proc Natl Sci Coun Repub China 1994; 18:101-106.
23. Harada S, Zhang S. New strategy for detection of ALDH2 mutant. Alcohol Alcohol 1993;28 (Suppl 1A):11S-13S.
24. Hayashi S-I, Watanabe J, Kawajiri K. Genetic polymorphisms in 5′-flanking region change transcriptional regulation of the human cytochrome P450IIE1 gene. J Biochem 1991;110:559-565.
25. Bosron WF, Li T-K, Catalytic properties of human liver alcohol dehydrogenase isoenzymes. Enzyme 1987;37:19-28.