Enhanced whole-body PET parametric imaging using hybrid regression and thresholding driven by kinetic correlations

IEEE Nuclear Science Symposium Conference Record

Volumn , Issue , 2012, Pages 4017-4027

  Karakatsanis, Nicolas A ^a   Lodge, Martin A ^a   Mohy Ud Din, Hassan ^a   Tahari, A K ^a   Zhou, Yun ^a   Wahl, Richard L ^a   Rahmim, Arman ^a  

^a Johns Hopkins University   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CLINICAL EVALUATION; COMPARATIVE EVALUATIONS; CONTRAST TO NOISE RATIO; ORDINARY LEAST SQUARES; QUANTITATIVE ACCURACY; STATISTICAL PARAMETER ESTIMATIONS; TUMOR DETECTABILITY; WEIGHTED CORRELATION COEFFICIENTS;

MEDICAL IMAGING; NUCLEAR MEDICINE; NUCLEAR PHYSICS; REGRESSION ANALYSIS; TUMORS;

PARAMETER ESTIMATION;

EID: 84881581246     PISSN: 10957863     EISSN: None     Source Type: Conference Proceeding    
DOI: 10.1109/NSSMIC.2012.6551920     Document Type: Conference Paper

References (50)

1. R. Wahl and J. Buchanan, Principles and practice of positron emission tomography. Lippincott Williams & Wilkins, 2002.
2. F. Castell and G. Cook, "Quantitative techniques in 18-FDG PET scanning in oncology," British Journal of Cancer, vol. 98, no. 10, pp. 1597-1601, 2008.
3. K. Facey, I. Bradbury, G. Laking, and E. Payne, "Overview of the clinical effectiveness of positron emission tomography imaging in selected cancers", Health Technology Assessment 2007, Vol. 11, No. 44.
4. M. Dahlbom, E. Hoffman, C. Hoh, C. Schiepers, G. Rosenqvist, R. Hawkins, M. Phelps et al., "Whole-body positron emission tomography: Part I. methods and performance characteristics." J Nucl. Med., vol. 33, no. 6, p. 1191, 1992.
5. R. Hustinx, F. Benard, and A. Alavi, "Whole-body FDG-PET imaging in the management of patients with cancer" Seminars in Nuclear Medicine, Vol. 32, No. 1. Elsevier, 2002, pp. 35-46.
6. K. Kubota, M. Itoh, K. Ozaki, S. Ono, M. Tashiro, K. Yamaguchi, T. Akaizawa, K. Yamada, and H. Fukuda, "Advantage of delayed wholebody FDG-PET imaging for tumor detection," Eur J of Nucl Med and Mol Imaging, vol. 28, no. 6, pp. 696-703, 2001.
7. D. Townsend, "Positron emission tomography/computed tomography" Seminars in Nuclear Medicine, Vol. 38, No. 3, Elsevier, 2008.
8. K. Zasadny and R. Wahl, "Standardized uptake values of normal tissues at PET with 2-[fluorine-18]-fluoro-2-deoxy-D-glucose: variations with body weight and a method for correction." Radiology, vol. 189, no. 3, p. 847, 1993.
9. C. Kim, N. Gupta et al, "Dependency of standardized uptake values of fluorine-18 fluorodeoxyglucose on body size: comparison of body surface area correction and lean body mass correction." Nuclear medicine communications, vol. 17, no. 10, p. 890, 1996.
10. C. Kim, N. Gupta, B. Chandramouli, A. Alavi et al., "Standardized uptake values of FDG: body surface area correction is preferable to body weight correction." Journal of Nuclear Medicine, vol. 35, no. 1, p. 164, 1994.
11. L. Hamberg, G. Hunter, N. Alpert, N. Choi, J. Babich, and A. Fischman, "The dose uptake ratio as an index of glucose metabolism: Useful parameter or oversimplification?" Journal of Nuclear Medicine, vol. 35, no. 8, p. 1308, 1994.
12. J. Keyes Jr et al., "SUV: Standard uptake or silly useless value?" Journal of Nuclear Medicine, vol. 36, no. 10, p. 1836, 1995.
13. S. Huang, "Anatomy of SUV," Nuclear Medicine and Biology, vol. 27, no. 7, pp. 643-646, 2000.
14. M. Adams, T. Turkington, J. Wilson, and T. Wong, "A systematic review of the factors affecting accuracy of SUV measurements," American Journal of Roentgenology, vol. 195, no. 2, pp. 310-320, 2010.
15. W. Weber, S. Ziegler, R. Th'odtmann, A. Hanauske, M. Schwaiger et al., "Reproducibility of metabolic measurements in malignant tumors using FDG PET." Journal of Nuclear Medicine, vol. 40, no. 11, p. 1771, 1999.
16. S. Leskinen-Kallio, K. Noagren, P. Lehikoinen, U. Ruotsalainen, M. Teras, H. Joensuu et al., "Carbon-11-methionine and PET is an effective method to image head and neck cancer." Journal of Nuclear Medicine, vol. 33, no. 5, p. 691, 1992.
17. N. Sadato, T. Tsuchida, S. Nakaumra, A. Waki, H. Uematsu, N. Takahashi, N. Hayashi, Y. Yonekura, and Y Ishii, "Non-invasive estimation of the net influx constant using the standardized uptake value for quantification of FDG uptake of tumors," Eur J of Nucl Med and Mol Imaging, Vol. 25, No. 6, pp. 559-564, 1998
18. W. Wong and K. Hicks, "A clinically practical method to acquire parametric images of unidirectional metabolic rates and blood spaces." J Nucl. Med., vol. 35, no. 7, p. 1206, 1994.
19. A. Dimitrakopoulou-Strauss, L. Strauss, M. Schwarzbach, C. Burger, T. Heichel, F. Willeke, G. Mechtersheimer, and T. Lehnert, "Dynamic PET 18F-FDG studies in patients with primary and recurrent soft-tissue sarcomas: impact on diagnosis and correlation with grading," J Nucl. Med., Vol. 42, No. 5, pp. 713-720, 2001.
20. N. A. Karakatsanis, M. A. Lodge, Y. Zhou, J. Mhlanga, M. Chaudhry, A. K. Tahari, W. P. Segars, R. L. Wahl, A. Rahmim, "Dynamic Multi-Bed FDG PET Imaging: Feasibility and Optimization", IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC), 2011, Valencia, Spain, p 3863-3871
21. N. A. Karakatsanis, M. A. Lodge, Y. Zhou, J. Mhlanga, A. K. Tahari, R. L. Wahl, A. Rahmim, "Towards Parametric Whole-Body FDG PET/CT Imaging: Potentials for Enhanced Tumor Detectability", J. Nucl. Med., vol. 53 (suppl. 1): 1236
22. K. R. Zasadny, R. L. Wahl, "Enhanced FDG-PET tumor imaging with correlation-coefficient filtered influx-constant images", J Nucl Med. 1996 Feb; 37(2): 371-4.
23. K. Zasadny and R. Wahl, "Standardized uptake values of normal tissues at PET with 2-[fluorine-18]-fluoro-2-deoxy-D-glucose: variations with body weight and a method for correction." Radiology, vol. 189, no. 3, p. 847, 1993.
24. S. Jan, D. Benoit, E. Becheva, T. Carlier, F. Cassol, P. Descourt, T. Frisson, L. Grevillot, L. Guigues, L. Maigne et al., "GATE V6: a major enhancement of the GATE simulation platform enabling modeling of CT and radiotherapy," Physics in Medicine and Biology, vol. 56, p. 881, 2011.
25. W. Segars, G. Sturgeon, S. Mendonca, J. Grimes, and B. Tsui, "4D XCAT phantom for multimodality imaging research," Medical Physics, vol. 37, p. 4902, 2010.
26. A. Dimitrakopoulou-Strauss, V. Georgoulias, M. Eisenhut, F. Herth, S. Koukouraki, H. Macke, U. Haberkorn, and L. Strauss, "Quantitative assessment of SSTR2 expression in patients with non-small cell lung cancer using 68 Ga-DOTATOC PET and comparison with 18 F-FDG PET," Eur J Nucl. Med. and Mol. Imaging, vol. 33, no. 7, pp. 823-830, 2006.
27. S. Okazumi, A. Dimitrakopoulou-Strauss, M. Schwarzbach, and L. Strauss, "Quantitative, dynamic 18F-FDG-PET for the evaluation of soft tissue sarcomas: relation to differential diagnosis, tumor grading and prediction of prognosis." Hel. J. Nucl. Med, vol. 12, no. 3, p. 223, 2009.
28. T. Torizuka, N. Tamaki, T. Inokuma, Y. Magata, S. Sasayama, Y. Yonekura, A. Tanaka, Y Yamaoka, K. Yamamoto, J. Konishi et al, "In vivo assessment of glucose metabolism in hepatocellular carcinoma with FDG-PET." J. Nucl. Med, vol. 36, no. 10, p. 1811, 1995.
29. Y Sugawara, K. Zasadny, H. Grossman, I. Francis, M. Clarke, and R. Wahl, "Germ cell tumor: Differentiation of viable tumor, mature teratoma, and necrotic tissue with FDG PET and kinetic modeling," Radiology, vol. 211, no. 1, pp. 249-256, 1999.
30. A. Dimitrakopoulou-Strauss, L. Strauss, and C. Burger, "Quantitative PET studies in pretreated melanoma patients: a comparison of 6-[18F] fluoro-L-dopa with 18F-FDG and 150-water using compartment and noncompartment analysis," J. Nucl. Med, vol. 42, no. 2, pp. 248-256, 2001.
31. A. Dimitrakopoulou-Strauss, L. Strauss, C. Burger, A. Ruhl, G. Irngartinger, W. Stremmel, and J. Rudi, "Prognostic aspects of 18F-FDG PET kinetics in patients with metastatic colorectal carcinoma receiving FOLFOX chemotherapy," J. Nucl. Med., vol. 45, no. 9, pp. 1480-1487, 2004.
32. L. Strauss, D. Koczan, S. Klippel, L. Pan, C. Cheng, S. Willis, U. Haberkorn, and A. Dimitrakopoulou-Strauss, "Impact of angiogenesis-related gene expression on the tracer kinetics of 18F-FDG in colorectal tumors" J Nucl. Med, vol. 49, no. 8, pp. 1238-1244, 2008.
33. L. Strauss, S. Klippel, L. Pan, K. Schonleben, U. Haberkorn, and A. Dimitrakopoulou-Strauss, "Assessment of quantitative FDG PET data in primary colorectal tumors: which parameters are important with respect to tumor detection?" Eur J Nucl. Med. and Mol. Imaging, vol. 34, no. 6, pp. 868-877, 2007.
34. H. Qiao, J. Bai, Y Chen, and J. Tian, "Kidney Modeling for FDG Excretion with PET," International Journal of Biomedical Imaging, vol. 2007, pp. 632-634, 2007.
35. K. Thielemans, S. Mustafovic, and C. Tsoumpas, "STIR: software for tomographic image reconstruction release 2," in Nuclear Science Symposium Conference Record, 2006. IEEE, vol. 4. IEEE, 2006, pp. 2174-2176.
36. C. Patlak, R. Blasberg, J. Fenstermacher et al., "Graphical evaluation of blood-to-brain transfer constants from multiple-time uptake data," J Cereb Blood Flow Metab, vol. 3, no. 1, pp. 1-7, 1983.
37. A. Gjedde, "High-and low-affinity transport of D-glucose from blood to brain," Journal of Neurochemistry, vol. 36, no. 4, pp. 1463-1471, 1981.
38. Y Zhou, W. Ye, J. Brasic, and D. Wong, "Multi-graphical analysis of dynamic PET," Neuroimage, vol. 49, no. 4, pp. 2947-2957, 2010.
39. C. Patlak and R. Blasberg, "Graphical evaluation of blood-to-brain transfer constants from multiple-time uptake data, generalizations," Journal of Cerebral Blood Flow & Metabolism, vol. 5, no. 4, pp. 584-590, 1985.
40. C. Messa, Y. Choi, C. Hoh, E. Jacobs, J. Glaspy, S. Rege, E. Nitzsche, S. Huang, M. Phelps, R. Hawkins et al., "Quantification of glucose utilization in liver metastases: parametric imaging of FDG uptake with PET." Journal of Computer Assisted Tomography, vol. 16, no. 5, p. 684, 1992.
41. A.E. Hoerl, R.W. Kennard, "Ridge Regression: Biased Estimation for Nonorthogonal Problems", Technometrics, Vol. 12, Issue 1, 1970, p 55-67
42. A.E. Hoerl, R.W. Kennard, "Ridge Regression: Applications to Nonorthogonal Problems", Vol. 12, Issue 1, 1970, p 69-82
43. D.Q. Marquardt, R.D. Snee, "Ridge Regression in Practice", The American Statistician, Vol. 29, Issue 1, 1975
44. A.E. Hoerl, R.W. Kennard, K.F. Baldwin, "Ridge regression some simulations", Comm. in Statistics, Vol. 4, No. 2. (1975), pp. 105-123
45. J.F. Lawless, P. Wang, "A simulation study of ridge and other regression estimators", Comm. In Statistics-Theory and Methods, Vol. 5, Issue 4, 1976
46. B.M.G. Kibria, "Performance of Some New Ridge Regression Estimators", Comm. in Statistics - Simulation and Computation, Vol. 32, Issue 2, 2003
47. G.H. Golub, M. Heath, G. Wahba, "Generalized Cross-Validation as a Method for Choosing a Good Ridge Parameter", Vol. 21, Issue 2, 1979
48. D.M. Allen, "Mean Square Error of Prediction as a Criterion for Selecting Variables", Technometrics, Vol. 13, No. 3, 1971, pp. 469-475
49. M D Walker, M-C Asselin, P J Julyan, M Feldmann, P S Talbot, T Jones and J C Matthews, "Bias in iterative reconstruction of low-statistics PET data: benefits of a resolution model", Phys. Med. Biol., 2011, 56, 931
50. Y Zhou, CJ Endres, JR Brasic, SC Huang, DF Wong "Linear regression with spatial constraint to generate parametric images of ligand-receptor dynamic PET studies with a simplified reference tissue model", NeuroImage, Vol. 18, Issue 4, 2003, p 975-989