Zinc ionophores pyrithione inhibits herpes simplex virus replication through interfering with proteasome function and NF-κB activation

Antiviral Research

Volumn 100, Issue 1, 2013, Pages 44-53

  Qiu, Min ^a   Chen, Yu ^a   Chu, Ying ^a   Song, Siwei ^a   Yang, Na ^a   Gao, Jie ^a   Wu, Zhiwei ^a  

^a NANJING UNIVERSITY   (China)

Author keywords

Antiviral activity; Herpes simplex virus; NF B; Pyrithione (PT); Ubiquitin proteasome system (UPS); Zinc ionophore

Indexed keywords

GLYCOPROTEIN D; I KAPPA B; I KAPPA B ALPHA; INFECTED CELL POLYPEPTIDE 4; IONOPHORE; POLYPEPTIDE; PROMYELOCYTIC LEUKEMIA PROTEIN; PROTEASOME; PYRITHIONE ZINC; UBIQUITIN; UNCLASSIFIED DRUG; ZINC ION; ANTIVIRUS AGENT; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PYRIDINE DERIVATIVE; PYRITHIONE; THIOKETONE; ZINC;

ANTIVIRAL ACTIVITY; ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; ENZYME ACTIVATION; ENZYME DEGRADATION; ENZYME INHIBITION; GENE EXPRESSION; HERPES SIMPLEX; HERPES SIMPLEX VIRUS 1; HERPES SIMPLEX VIRUS 2; HUMAN; HUMAN CELL; IMMEDIATE EARLY GENE; PRIORITY JOURNAL; PROGENY; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN STABILITY; SIGNAL TRANSDUCTION; VIRUS INHIBITION; VIRUS REPLICATION; DOWN REGULATION; DRUG EFFECT; ENZYMOLOGY; GENETICS; HERPES SIMPLEX VIRUS; METABOLISM; NF-ΚB; PHYSIOLOGY; PYRITHIONE (PT); UBIQUITIN-PROTEASOME SYSTEM (UPS); VIROLOGY; ZINC IONOPHORE;

HUMAN HERPESVIRUS 2; RNA VIRUSES; SIMPLEXVIRUS; STAPHYLOCOCCUS; STREPTOCOCCUS;

ANTIVIRAL ACTIVITY; HERPES SIMPLEX VIRUS; NF-ΚB; PYRITHIONE (PT); UBIQUITIN-PROTEASOME SYSTEM (UPS); ZINC IONOPHORE;

ANTIVIRAL AGENTS; DOWN-REGULATION; HERPES SIMPLEX; HERPESVIRUS 1, HUMAN; HERPESVIRUS 2, HUMAN; HUMANS; IONOPHORES; NF-KAPPA B; PROTEASOME ENDOPEPTIDASE COMPLEX; PYRIDINES; THIONES; VIRUS REPLICATION; ZINC;

EID: 84881538410     PISSN: 01663542     EISSN: 18729096     Source Type: Journal    
DOI: 10.1016/j.antiviral.2013.07.001     Document Type: Article

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