Inhibitory effects of sigma-2 receptor agonists on T lymphocyte activation

Frontiers in Pharmacology

Volumn 4 MAR, Issue , 2013, Pages

  Iñiguez, Miguel A ^a   Punzón, Carmen ^a   Nieto, Raquel ^a   Burgueño, Javier ^b   Vela, José M ^b   Fresno, Manuel ^a  

^a UNIVERSIDAD AUTÓNOMA DE MADRID   (Spain)

^b Laboratorios Esteve   (Spain)

Author keywords

Nuclear factor of activated T cells; Nuclear factor B; Sigma receptor; T lymphocytes; Transcriptional regulation

Indexed keywords

1 [2 (3,4 DICHLOROPHENYL)ETHYL] N METHYL 2 (1 PYRROLIDINYL)CYCLOHEXYLAMINE; 1 PHENYLCYCLOHEXANECARBOXYLIC ACID 2 MORPHOLINOETHYL ESTER; AC 927; BD 1063; CB 184; CYCLOOXYGENASE 2; CYCLOSPORIN A; INTERLEUKIN 1; N [2 (3,4 DICHLOROPHENYL)ETHYL] N METHYL 2 (1 PYRROLIDINYL)CYCLOHEXYLAMINE; N PHENETHYLPIPERIDINE OXALATE; OPIATE AGONIST; OPIATE ANTAGONIST; PRE O84; RUXOLITINIB; SIGMA 1 OPIATE RECEPTOR; SIGMA 2 OPIATE RECEPTOR; SIGMA 2 OPIATE RECEPTOR AGONIST; SIGMA 2 OPIATE RECEPTOR ANTAGONIST; TRANSCRIPTION FACTOR NFAT; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DOWN REGULATION; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; IMMUNOMODULATION; IMMUNOREGULATION; LEUKEMIA CELL LINE; LIGAND BINDING; PHARMACOLOGICAL BLOCKING; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; T LYMPHOCYTE ACTIVATION; TRANSCRIPTION INITIATION; TRANSCRIPTION REGULATION;

EID: 84881528156     PISSN: None     EISSN: 16639812     Source Type: Journal    
DOI: 10.3389/fphar.2013.00023     Document Type: Article

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