GSK3β is a checkpoint for TNF-α-mediated impaired osteogenic differentiation of mesenchymal stem cells in inflammatory microenvironments

Biochimica et Biophysica Acta - General Subjects

Volumn 1830, Issue 11, 2013, Pages 5119-5129

  Kong, Xiangwei ^a,b   Liu, Yan ^a   Ye, Ruidong ^c   Zhu, Bin ^a   Zhu, Yuan ^a   Liu, Xianghui ^b   Hu, Chenghu ^a   Luo, Hailang ^a   Zhang, Yongjie ^a   Ding, Yin ^a   Jin, Yan ^a  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^b Nanjing Bayi Hospital   (China)

^c MEDICAL SCHOOL OF NANJING UNIVERSITY   (China)

Author keywords

Glycogen synthase kinase 3 ; Mesenchymal stem cell; Osteogenic differentiation; Tumor necrosis factor

Indexed keywords

BETA CATENIN; GLYCOGEN SYNTHASE KINASE 3BETA; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; LIPOPOLYSACCHARIDE; LYMPHOID ENHANCER FACTOR 1; SMALL INTERFERING RNA; T CELL FACTOR PROTEIN; TRANSCRIPTION FACTOR RUNX2; TUMOR NECROSIS FACTOR ALPHA;

ADENOVIRUS; ADULT; ARTICLE; BIOACCUMULATION; BONE DEVELOPMENT; CELL DAMAGE; CELL DIFFERENTIATION; CELL FUNCTION; CELL ISOLATION; CELL NUCLEUS; CELL POPULATION; CELL STIMULATION; CELL TYPE; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINE RELEASE; ENZYME INACTIVATION; ENZYME PHOSPHORYLATION; ENZYME REGULATION; HUMAN; HUMAN CELL; HUMAN TISSUE; INFLAMMATION; MESENCHYMAL STEM CELL; MICROENVIRONMENT; MONOCYTE; OSTEOBLAST; PERIODONTAL LIGAMENT; PERIODONTITIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION;

GLYCOGEN SYNTHASE KINASE 3Β; MESENCHYMAL STEM CELL; OSTEOGENIC DIFFERENTIATION; TUMOR NECROSIS FACTOR-Α;

ADULT; BETA CATENIN; CELL DIFFERENTIATION; CELL NUCLEUS; CELLS, CULTURED; CORE BINDING FACTOR ALPHA 1 SUBUNIT; GLYCOGEN SYNTHASE KINASE 3; HUMANS; INFLAMMATION; INTERLEUKINS; LYMPHOID ENHANCER-BINDING FACTOR 1; MESENCHYMAL STROMAL CELLS; MONOCYTES; OSTEOGENESIS; PERIODONTAL LIGAMENT; PERIODONTITIS; PHOSPHORYLATION; STEM CELL NICHE; TUMOR NECROSIS FACTOR-ALPHA; YOUNG ADULT;

EID: 84881504150     PISSN: 03044165     EISSN: 18728006     Source Type: Journal    
DOI: 10.1016/j.bbagen.2013.07.027     Document Type: Article

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