Reactivating head regrowth in a regeneration-deficient planarian species

Nature

Volumn 500, Issue 7460, 2013, Pages 81-84

  Liu, S Y ^a   Selck, C ^b   Friedrich, B ^b   Lutz, R ^b   Vila Farre M ^a   Dahl, A ^b   Brandl, H ^a   Lakshmanaperumal, N ^a   Henry, I ^a   Rink, J C ^a,b  

^a MAX PLANCK INSTITUTE OF MOLECULAR CELL BIOLOGY AND GENETICS   (Germany)

^b CENTER FOR REGENERATIVE THERAPIES DRESDEN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BETA CATENIN;

ANIMAL COMMUNITY; REACTIVATION; REGENERATION; REGROWTH; RNA; SIGNAL;

ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; DENDROCOELUM LACTEUM; GENE SILENCING; HEAD; HISTOLOGY; MICROBIAL GROWTH; MICROMORPHOLOGY; MOLECULAR EVOLUTION; NONHUMAN; PRIORITY JOURNAL; REGENERATION; REGENERATIVE ABILITY; RNA INTERFERENCE; SIGNAL TRANSDUCTION; TAIL; TURBELLARIA; WNT SIGNALING PATHWAY;

ANIMALS; BETA CATENIN; BODY PATTERNING; HEAD; MODELS, ANIMAL; MOLECULAR SEQUENCE DATA; PLANARIANS; REGENERATION; TAIL; WNT PROTEINS; WNT SIGNALING PATHWAY;

ANIMALIA; DENDROCOELUM LACTEUM; PLANARIA; PLATYHELMINTHES; TURBELLARIA;

EID: 84881481616     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature12414     Document Type: Article

References (39)

1. Sánchez Alvarado, A.&Tsonis, P. A. Bridgingthe regenerationgap: genetic insights from diverse animal models. Nature Rev. Genet. 7, 873-884 (2006)
2. Tanaka, E. M. Regeneration: if they can do it, why can't we? Cell 113, 559-562 (2003)
3. Bely, A. E.&Nyberg, K. G. Evolution of animal regeneration: re-emergence of a field. Trends Ecol. Evol. 25, 161-170 (2010)
4. Brondsted, H. V. Planarian regeneration (Pergamon Press, 1969)
5. Morgan, T. H. Notes on regeneration. Biol. Bull. 6, 159-172 (1904)
6. Gurley, K. A., Rink, J. C. & Sánchez Alvarado, A. b-catenin defines head versus tail identity during planarian regeneration and homeostasis. Science 319, 323-327 (2008)
7. Petersen, C. P. & Reddien, P. W. Smed-bcatenin-1 is required for anteroposterior blastema polarity in planarian regeneration. Science 319, 327-330 (2008)
8. Iglesias, M., Gómez-Skarmeta, J. L., Saló, E. & Adell, T. Silencing of Smed-bcatenin1 generates radial-like hypercephalized planarians. Development 135, 1215-1221 (2008)
9. Agata, K.& Watanabe, K.Molecular and cellular aspects of planarian regeneration. Semin. Cell Dev. Biol. 10, 377-383 (1999)
10. Newmark, P. A.&Sánchez Alvarado, A.Not your father's planarian: a classicmodel enters the era of functional genomics. Nature Rev. Genet. 3, 210-219 (2002)
11. Schockaert, E. R. et al. Global diversity of free living flatworms (Platyhelminthes, 'Turbellaria') in freshwater. Hydrobiologia 595, 41-48 (2008)
12. Stéphan-Dubois, F. & Gilgenkrantz, F. Transplantation et régénération chez la planaire Dendrocoelum lacteum. J. Embryol. Exp. Morphol. 9, 642-649 (1961)
13. Stéphan-Dubois, F.&Bautz, A.Étude histologique et cytologique des néoblastes et des cellules fixes du parenchyme chez des planaires Dendrocoelum lacteum privées de région anterieure. Arch. Anat. Microsc. Morphol. Exp. 64, 75-89 (1975)
14. Sauzin-Monnot, M.-J. Etude ultrastructurale des néoblastes de Dendrocoelum lacteum au cours de la régénération. J. Ultrastruct. Res. 45, 206-222 (1973)
15. Parra, G., Bradnam, K. & Korf, I. CEGMA: a pipeline to accurately annotate core genes in eukaryotic genomes. Bioinformatics 23, 1061-1067 (2007)
16. Cebria, F. et al. FGFR-related gene nou-darake restricts brain tissues to the head region of planarians. Nature 419, 620-624 (2002)
17. Gurley, K. A. et al. Expression of secreted Wnt pathway components reveals unexpected complexity of the planarian amputation response. Dev. Biol. 347, 24-39 (2010)
18. Rink, J. C. Stem cell systems and regeneration in planaria. Dev. Genes Evol. 223, 67-84 (2013)
19. Tanaka, E. M. & Reddien, P. W. The cellular basis for animal regeneration. Dev. Cell 21, 172-185 (2011)
20. Wenemoser, D., Lapan, S. W., Wilkinson, A. W., Bell, G. W. & Reddien, P. W. A molecular wound response program associated with regeneration initiation in planarians. Genes Dev. 26, 988-1002 (2012)
21. Reddien, P. W., Bermange, A. L., Kicza, A. M. & Sánchez Alvarado, A.BMP signaling regulates the dorsal planarian midline and is needed for asymmetric regeneration. Development 134, 4043-4051 (2007)
22. Petersen, C. P. & Reddien, P. W. Polarized notum activation at wounds inhibits Wnt function to promote planarian head regeneration. Science 332, 852-855 (2011)
23. Rink, J. C., Gurley, K. A., Elliott, S. A. & Sánchez Alvarado, A. Planarian Hh signaling regulates regeneration polarity and links Hh pathway evolution to cilia. Science 326, 1406-1410 (2009)
24. Beane, W. S., Morokuma, J., Adams, D. S.& Levin, M. A chemical genetics approach reveals H,K-ATPase-mediated membrane voltage is required for planarian head regeneration. Chem. Biol. 18, 77-89 (2011)
25. Felix, D. A. & Aboobaker, A. A. The TALE class homeobox gene Smed-prep defines the anterior compartment for head regeneration. PLoS Genet. 6, e1000915 (2010)
26. Blassberg, R. A., Felix, D. A., Tejada Romero, B. & Aboobaker, A. A. PBX/extradenticle is required to re-establish axial structures and polarity during planarian regeneration. Development 140, 730-739 (2013)
27. Chen, C.-C. G., Wang, I. E. & Reddien, P. W. pbx is required for pole and eye regeneration in planarians. Development 140, 719-729 (2013)
28. Petersen, C. P. & Reddien, P. W. A wound-induced Wnt expression program controls planarian regeneration polarity. Proc. Natl Acad. Sci. USA 106, 17061-17066 (2009)
29. Eisenhoffer, G. T., Kang, H. & Sánchez Alvarado, A. Molecular analysis of stem cells and their descendants during cell turnover and regeneration in the planarian Schmidtea mediterranea. Cell Stem Cell 3, 327-339 (2008)
30. Grabherr, M. G. et al. Full-length transcriptome assembly from RNA-Seq data without a reference genome. Nature Biotechnol. 29, 644-652 (2011)
31. Langmead, B. & Salzberg, S. L. Fast gapped-read alignment with Bowtie 2. Nature Methods 9, 357-359 (2012)
32. Li, H. et al. The sequence alignment/map format and SAMtools. Bioinformatics 25, 2078-2079 (2009)
33. Rice, P., Longden, I.& Bleasby, A.EMBOSS: The European Molecular Biology Open Software Suite. Trends Genet. 16, 276-277 (2000)
34. Quevillon, E. et al. InterProScan: protein domains identifier. Nucleic Acids Res. 33, W116-W120 (2005)
35. Altschul, S. F., Gish, W., Miller, W., Myers, E. W.& Lipman, D. J. Basic local alignment search tool. J. Mol. Biol. 215, 403-410 (1990)
36. Pearson, B. J. et al. Formaldehyde-based whole-mount in situ hybridization method for planarians. Dev. Dyn. 238, 443-450 (2009)
37. Schindelin, J. et al. Fiji: an open-source platform for biological image analysis. Nature Methods 9, 676-682 (2012)
38. Cebria, F. & Newmark, P. A. Planarian homologs of netrin and netrin receptor are required for proper regeneration of the central nervous system and the maintenance of nervous system architecture. Development 132, 3691-3703 (2005)
39. Buchholz, F., Kittler, R., Slabicki, M. & Theis, M. Enzymatically prepared RNAi libraries. Nature Methods 3, 696-700 (2006)