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Volumn 108, Issue 5, 2011, Pages 318-325

Doxycycline Dose-dependently Inhibits MMP-2-Mediated Vascular Changes in 2K1C Hypertension

Author keywords

[No Author keywords available]

Indexed keywords

DOXYCYCLINE; GELATINASE A;

EID: 79954524108     PISSN: 17427835     EISSN: 17427843     Source Type: Journal    
DOI: 10.1111/j.1742-7843.2010.00656.x     Document Type: Article
Times cited : (48)

References (37)
  • 1
    • 37349082926 scopus 로고    scopus 로고
    • Matrix metalloproteinases and their inhibitors in vascular remodeling and vascular disease
    • Raffetto JD, Khalil RA. Matrix metalloproteinases and their inhibitors in vascular remodeling and vascular disease. Biochem Pharmacol 2008;75:346-59.
    • (2008) Biochem Pharmacol , vol.75 , pp. 346-359
    • Raffetto, J.D.1    Khalil, R.A.2
  • 3
    • 33750220329 scopus 로고    scopus 로고
    • Atherosclerotic process, renovascular disease and outcomes from bench to bedside
    • Lerman LO, Chade AR. Atherosclerotic process, renovascular disease and outcomes from bench to bedside. Curr Opin Nephrol Hypertens 2006;15:583-7.
    • (2006) Curr Opin Nephrol Hypertens , vol.15 , pp. 583-587
    • Lerman, L.O.1    Chade, A.R.2
  • 4
    • 33751568473 scopus 로고    scopus 로고
    • Renovascular hypertension update
    • Textor SC. Renovascular hypertension update. Curr Hypertens Rep 2006;8:521-7.
    • (2006) Curr Hypertens Rep , vol.8 , pp. 521-527
    • Textor, S.C.1
  • 5
    • 33847020733 scopus 로고    scopus 로고
    • Intracellular targets of matrix metalloproteinase-2 in cardiac disease: rationale and therapeutic approaches
    • Schulz R. Intracellular targets of matrix metalloproteinase-2 in cardiac disease: rationale and therapeutic approaches. Annu Rev Pharmacol Toxicol 2007;47:211-42.
    • (2007) Annu Rev Pharmacol Toxicol , vol.47 , pp. 211-242
    • Schulz, R.1
  • 6
    • 31344462860 scopus 로고    scopus 로고
    • Vascular remodeling and protease inhibition--bench to bedside
    • Sluijter JP, de Kleijn DP, Pasterkamp G. Vascular remodeling and protease inhibition--bench to bedside. Cardiovasc Res 2006;69:595-603.
    • (2006) Cardiovasc Res , vol.69 , pp. 595-603
    • Sluijter, J.P.1    de Kleijn, D.P.2    Pasterkamp, G.3
  • 7
    • 31344447802 scopus 로고    scopus 로고
    • Matrix metalloproteinases regulate migration, proliferation, and death of vascular smooth muscle cells by degrading matrix and non-matrix substrates
    • Newby AC. Matrix metalloproteinases regulate migration, proliferation, and death of vascular smooth muscle cells by degrading matrix and non-matrix substrates. Cardiovasc Res 2006;69:614-24.
    • (2006) Cardiovasc Res , vol.69 , pp. 614-624
    • Newby, A.C.1
  • 8
    • 13244283349 scopus 로고    scopus 로고
    • Matrix metalloproteinase-9 (MMP-9), MMP-2, and serum elastase activity are associated with systolic hypertension and arterial stiffness
    • Yasmin SW, McEniery CM, Dakham Z, Pulsalkar P, Maki-Petaja K, Ashby MJ et al. Matrix metalloproteinase-9 (MMP-9), MMP-2, and serum elastase activity are associated with systolic hypertension and arterial stiffness. Arterioscler Thromb Vasc Biol 2005;25:372.
    • (2005) Arterioscler Thromb Vasc Biol , vol.25 , pp. 372
    • Yasmin, S.W.1    McEniery, C.M.2    Dakham, Z.3    Pulsalkar, P.4    Maki-Petaja, K.5    Ashby, M.J.6
  • 9
    • 33646439273 scopus 로고    scopus 로고
    • Matrix metalloproteinases/tissue inhibitors of metalloproteinases: relationship between changes in proteolytic determinants of matrix composition and structural, functional, and clinical manifestations of hypertensive heart disease
    • Ahmed SH, Clark LL, Pennington WR, Webb CS, Bonnema DD, Leonardi AH et al. Matrix metalloproteinases/tissue inhibitors of metalloproteinases: relationship between changes in proteolytic determinants of matrix composition and structural, functional, and clinical manifestations of hypertensive heart disease. Circulation 2006;113:2089-96.
    • (2006) Circulation , vol.113 , pp. 2089-2096
    • Ahmed, S.H.1    Clark, L.L.2    Pennington, W.R.3    Webb, C.S.4    Bonnema, D.D.5    Leonardi, A.H.6
  • 10
    • 14644401767 scopus 로고    scopus 로고
    • Different involvement of extracellular matrix components in small and large arteries during chronic NO synthase inhibition
    • Bouvet C, Gilbert LA, Girardot D, deBlois D, Moreau P. Different involvement of extracellular matrix components in small and large arteries during chronic NO synthase inhibition. Hypertension 2005;45:432-7.
    • (2005) Hypertension , vol.45 , pp. 432-437
    • Bouvet, C.1    Gilbert, L.A.2    Girardot, D.3    deBlois, D.4    Moreau, P.5
  • 11
    • 34250796742 scopus 로고    scopus 로고
    • Morphological and biochemical characterization of remodeling in aorta and vena cava of DOCA-salt hypertensive rats
    • Watts SW, Rondelli C, Thakali K, Li X, Uhal B, Pervaiz MH et al. Morphological and biochemical characterization of remodeling in aorta and vena cava of DOCA-salt hypertensive rats. Am J Physiol Heart Circ Physiol 2007;292:H2438-48.
    • (2007) Am J Physiol Heart Circ Physiol , vol.292
    • Watts, S.W.1    Rondelli, C.2    Thakali, K.3    Li, X.4    Uhal, B.5    Pervaiz, M.H.6
  • 12
    • 1442334650 scopus 로고    scopus 로고
    • Pressure-induced matrix metalloproteinase-9 contributes to early hypertensive remodeling
    • Lehoux S, Lemarie CA, Esposito B, Lijnen HR, Tedgui A. Pressure-induced matrix metalloproteinase-9 contributes to early hypertensive remodeling. Circulation 2004;109:1041-7.
    • (2004) Circulation , vol.109 , pp. 1041-1047
    • Lehoux, S.1    Lemarie, C.A.2    Esposito, B.3    Lijnen, H.R.4    Tedgui, A.5
  • 14
    • 48749128063 scopus 로고    scopus 로고
    • Lercanidipine reduces matrix metalloproteinase-2 activity and reverses vascular dysfunction in renovascular hypertensive rats
    • Martinez ML, Castro MM, Rizzi E, Fernandes K, Demacq C, Bendhack LM et al. Lercanidipine reduces matrix metalloproteinase-2 activity and reverses vascular dysfunction in renovascular hypertensive rats. Eur J Pharmacol 2008;591:224-30.
    • (2008) Eur J Pharmacol , vol.591 , pp. 224-230
    • Martinez, M.L.1    Castro, M.M.2    Rizzi, E.3    Fernandes, K.4    Demacq, C.5    Bendhack, L.M.6
  • 15
    • 43949099942 scopus 로고    scopus 로고
    • Metalloproteinase inhibition ameliorates hypertension and prevents vascular dysfunction and remodeling in renovascular hypertensive rats
    • Castro MM, Rizzi E, Figueiredo-Lopes L, Fernandes K, Bendhack LM, Pitol DL et al. Metalloproteinase inhibition ameliorates hypertension and prevents vascular dysfunction and remodeling in renovascular hypertensive rats. Atherosclerosis 2008;198:320-31.
    • (2008) Atherosclerosis , vol.198 , pp. 320-331
    • Castro, M.M.1    Rizzi, E.2    Figueiredo-Lopes, L.3    Fernandes, K.4    Bendhack, L.M.5    Pitol, D.L.6
  • 16
    • 77950864155 scopus 로고    scopus 로고
    • Imbalance between matrix metalloproteinases and tissue inhibitor of metalloproteinases in hypertensive vascular remodeling
    • Castro MM, Rizzi E, Prado CM, Rossi MA, Tanus-Santos JE, Gerlach RF. Imbalance between matrix metalloproteinases and tissue inhibitor of metalloproteinases in hypertensive vascular remodeling. Matrix Biol 2010;29:194-201.
    • (2010) Matrix Biol , vol.29 , pp. 194-201
    • Castro, M.M.1    Rizzi, E.2    Prado, C.M.3    Rossi, M.A.4    Tanus-Santos, J.E.5    Gerlach, R.F.6
  • 17
    • 1842738493 scopus 로고    scopus 로고
    • Subantimicrobial dose doxycycline efficacy as a matrix metalloproteinase inhibitor in chronic periodontitis patients is enhanced when combined with a non-steroidal anti-inflammatory drug
    • Lee HM, Ciancio SG, Tuter G, Ryan ME, Komaroff E, Golub LM. Subantimicrobial dose doxycycline efficacy as a matrix metalloproteinase inhibitor in chronic periodontitis patients is enhanced when combined with a non-steroidal anti-inflammatory drug. J Periodontol 2004;75:453-63.
    • (2004) J Periodontol , vol.75 , pp. 453-463
    • Lee, H.M.1    Ciancio, S.G.2    Tuter, G.3    Ryan, M.E.4    Komaroff, E.5    Golub, L.M.6
  • 18
    • 0032200444 scopus 로고    scopus 로고
    • Tetracyclines inhibit connective tissue breakdown by multiple non-antimicrobial mechanisms
    • Golub LM, Lee HM, Ryan ME, Giannobile WV, Payne J, Sorsa T. Tetracyclines inhibit connective tissue breakdown by multiple non-antimicrobial mechanisms. Adv Dent Res 1998;12:12-26.
    • (1998) Adv Dent Res , vol.12 , pp. 12-26
    • Golub, L.M.1    Lee, H.M.2    Ryan, M.E.3    Giannobile, W.V.4    Payne, J.5    Sorsa, T.6
  • 20
    • 0037126045 scopus 로고    scopus 로고
    • Intracellular action of matrix metalloproteinase-2 accounts for acute myocardial ischemia and reperfusion injury
    • Wang W, Schulze CJ, Suarez-Pinzon WL, Dyck JR, Sawicki G, Schulz R. Intracellular action of matrix metalloproteinase-2 accounts for acute myocardial ischemia and reperfusion injury. Circulation 2002;106:1543-9.
    • (2002) Circulation , vol.106 , pp. 1543-1549
    • Wang, W.1    Schulze, C.J.2    Suarez-Pinzon, W.L.3    Dyck, J.R.4    Sawicki, G.5    Schulz, R.6
  • 21
    • 32444441006 scopus 로고    scopus 로고
    • Effect of matrix metalloproteinase inhibition by doxycycline on myocardial healing and remodeling after myocardial infarction
    • Tessone A, Feinberg MS, Barbash IM, Reich R, Holbova R, Richmann M et al. Effect of matrix metalloproteinase inhibition by doxycycline on myocardial healing and remodeling after myocardial infarction. Cardiovasc Drugs Ther 2005;19:383-90.
    • (2005) Cardiovasc Drugs Ther , vol.19 , pp. 383-390
    • Tessone, A.1    Feinberg, M.S.2    Barbash, I.M.3    Reich, R.4    Holbova, R.5    Richmann, M.6
  • 22
    • 0345167810 scopus 로고    scopus 로고
    • Mechanism of inhibition of matrix metalloproteinase-2 expression by doxycycline in human aortic smooth muscle cells
    • Liu J, Xiong W, Baca-Regen L, Nagase H, Baxter BT. Mechanism of inhibition of matrix metalloproteinase-2 expression by doxycycline in human aortic smooth muscle cells. J Vasc Surg 2003;38:1376-83.
    • (2003) J Vasc Surg , vol.38 , pp. 1376-1383
    • Liu, J.1    Xiong, W.2    Baca-Regen, L.3    Nagase, H.4    Baxter, B.T.5
  • 23
    • 0141839055 scopus 로고    scopus 로고
    • Early short-term treatment with doxycycline modulates postinfarction left ventricular remodeling
    • Villarreal FJ, Griffin M, Omens J, Dillmann W, Nguyen J, Covell J. Early short-term treatment with doxycycline modulates postinfarction left ventricular remodeling. Circulation 2003;108:1487-92.
    • (2003) Circulation , vol.108 , pp. 1487-1492
    • Villarreal, F.J.1    Griffin, M.2    Omens, J.3    Dillmann, W.4    Nguyen, J.5    Covell, J.6
  • 24
  • 25
    • 34948852291 scopus 로고    scopus 로고
    • Acute actions and novel targets of matrix metalloproteinases in the heart and vasculature
    • Chow AK, Cena J, Schulz R. Acute actions and novel targets of matrix metalloproteinases in the heart and vasculature. Br J Pharmacol 2007;152:189-205.
    • (2007) Br J Pharmacol , vol.152 , pp. 189-205
    • Chow, A.K.1    Cena, J.2    Schulz, R.3
  • 27
    • 0034755768 scopus 로고    scopus 로고
    • Norepinephrine-induced aortic hyperplasia and extracellular matrix deposition are endothelin-dependent
    • Dao HH, Lemay J, de Champlain J, deBlois D, Moreau P. Norepinephrine-induced aortic hyperplasia and extracellular matrix deposition are endothelin-dependent. J Hypertens 2001;19:1965-73.
    • (2001) J Hypertens , vol.19 , pp. 1965-1973
    • Dao, H.H.1    Lemay, J.2    de Champlain, J.3    deBlois, D.4    Moreau, P.5
  • 28
    • 17044378476 scopus 로고    scopus 로고
    • Methodological issues affecting the determination of plasma matrix metalloproteinase (MMP)-2 and MMP-9 activities
    • Souza-Tarla CD, Uzuelli JA, Machado AA, Gerlach RF, Tanus-Santos JE. Methodological issues affecting the determination of plasma matrix metalloproteinase (MMP)-2 and MMP-9 activities. Clin Biochem 2005;38:410-4.
    • (2005) Clin Biochem , vol.38 , pp. 410-414
    • Souza-Tarla, C.D.1    Uzuelli, J.A.2    Machado, A.A.3    Gerlach, R.F.4    Tanus-Santos, J.E.5
  • 29
    • 27644503201 scopus 로고    scopus 로고
    • Effect of anticoagulants on the determination of plasma matrix metalloproteinase (MMP)-2 and MMP-9 activities
    • Gerlach RF, Uzuelli JA, Souza-Tarla CD, Tanus-Santos JE. Effect of anticoagulants on the determination of plasma matrix metalloproteinase (MMP)-2 and MMP-9 activities. Anal Biochem 2005;344:147-9.
    • (2005) Anal Biochem , vol.344 , pp. 147-149
    • Gerlach, R.F.1    Uzuelli, J.A.2    Souza-Tarla, C.D.3    Tanus-Santos, J.E.4
  • 30
    • 33845749224 scopus 로고    scopus 로고
    • Rapid separation of serum does not avoid artificially higher matrix metalloproteinase (MMP)-9 levels in serum versus plasma
    • Gerlach RF, Demacq C, Jung K, Tanus-Santos JE. Rapid separation of serum does not avoid artificially higher matrix metalloproteinase (MMP)-9 levels in serum versus plasma. Clin Biochem 2007;40:119-23.
    • (2007) Clin Biochem , vol.40 , pp. 119-123
    • Gerlach, R.F.1    Demacq, C.2    Jung, K.3    Tanus-Santos, J.E.4
  • 31
    • 63349099519 scopus 로고    scopus 로고
    • Antioxidant treatment reduces matrix metalloproteinase-2-induced vascular changes in renovascular hypertension
    • Castro MM, Rizzi E, Rodrigues GJ, Ceron CS, Bendhack LM, Gerlach RF et al. Antioxidant treatment reduces matrix metalloproteinase-2-induced vascular changes in renovascular hypertension. Free Radic Biol Med 2009;46:1298-307.
    • (2009) Free Radic Biol Med , vol.46 , pp. 1298-1307
    • Castro, M.M.1    Rizzi, E.2    Rodrigues, G.J.3    Ceron, C.S.4    Bendhack, L.M.5    Gerlach, R.F.6
  • 32
    • 34250017173 scopus 로고    scopus 로고
    • Effects of timed administration of doxycycline or methylprednisolone on post-myocardial infarction inflammation and left ventricular remodeling in the rat heart
    • Garcia RA, Go KV, Villarreal FJ. Effects of timed administration of doxycycline or methylprednisolone on post-myocardial infarction inflammation and left ventricular remodeling in the rat heart. Mol Cell Biochem 2007;300:159-69.
    • (2007) Mol Cell Biochem , vol.300 , pp. 159-169
    • Garcia, R.A.1    Go, K.V.2    Villarreal, F.J.3
  • 33
    • 15844380045 scopus 로고    scopus 로고
    • Reduction of myocardial infarct size by doxycycline: a role for plasmin inhibition
    • Griffin MO, Jinno M, Miles LA, Villarreal FJ. Reduction of myocardial infarct size by doxycycline: a role for plasmin inhibition. Mol Cell Biochem 2005;270:1-11.
    • (2005) Mol Cell Biochem , vol.270 , pp. 1-11
    • Griffin, M.O.1    Jinno, M.2    Miles, L.A.3    Villarreal, F.J.4
  • 34
    • 49849086014 scopus 로고    scopus 로고
    • Chronic doxycycline exposure accelerates left ventricular hypertrophy and progression to heart failure in mice after thoracic aorta constriction
    • Vinet L, Rouet-Benzineb P, Marniquet X, Pellegrin N, Mangin L, Louedec L et al. Chronic doxycycline exposure accelerates left ventricular hypertrophy and progression to heart failure in mice after thoracic aorta constriction. Am J Physiol Heart Circ Physiol 2008;295:H352-60.
    • (2008) Am J Physiol Heart Circ Physiol , vol.295
    • Vinet, L.1    Rouet-Benzineb, P.2    Marniquet, X.3    Pellegrin, N.4    Mangin, L.5    Louedec, L.6
  • 35
    • 77950930269 scopus 로고    scopus 로고
    • Spironolactone and hydrochlorothiazide exert antioxidant effects and reduce vascular matrix metalloproteinase-2 activity and expression in a model of renovascular hypertension
    • Ceron CS, Castro MM, Rizzi E, Montenegro MF, Fontana V, Salgado MC et al. Spironolactone and hydrochlorothiazide exert antioxidant effects and reduce vascular matrix metalloproteinase-2 activity and expression in a model of renovascular hypertension. Br J Pharmacol 2010;160:77-87.
    • (2010) Br J Pharmacol , vol.160 , pp. 77-87
    • Ceron, C.S.1    Castro, M.M.2    Rizzi, E.3    Montenegro, M.F.4    Fontana, V.5    Salgado, M.C.6
  • 36
    • 0036584883 scopus 로고    scopus 로고
    • Doxycycline in patients with abdominal aortic aneurysms and in mice: comparison of serum levels and effect on aneurysm growth in mice
    • Prall AK, Longo GM, Mayhan WG, Waltke EA, Fleckten B, Thompson RW et al. Doxycycline in patients with abdominal aortic aneurysms and in mice: comparison of serum levels and effect on aneurysm growth in mice. J Vasc Surg 2002;35:923-9.
    • (2002) J Vasc Surg , vol.35 , pp. 923-929
    • Prall, A.K.1    Longo, G.M.2    Mayhan, W.G.3    Waltke, E.A.4    Fleckten, B.5    Thompson, R.W.6
  • 37
    • 0024271676 scopus 로고
    • Clinical pharmacokinetics of doxycycline and minocycline
    • Saivin S, Houin G. Clinical pharmacokinetics of doxycycline and minocycline. Clin Pharmacokinet 1988;15:355-66.
    • (1988) Clin Pharmacokinet , vol.15 , pp. 355-366
    • Saivin, S.1    Houin, G.2


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