TPL-2-ERK1/2 signaling promotes host resistance against intracellular bacterial infection by negative regulation of type I IFN production

Journal of Immunology

Volumn 191, Issue 4, 2013, Pages 1732-1743

  McNab, Finlay W ^a   Ewbank, John ^a   Rajsbaum, Ricardo ^a,b   Stavropoulos, Evangelos ^a   Martirosyan, Anna ^a   Redford, Paul S ^a   Wu, Xuemei ^a   Graham, Christine M ^a   Saraiva, Margarida ^c,d   Tsichlis, Philip ^e   Chaussabel, Damien ^f,g   Ley, Steven C ^a   O'Garra, Anne ^a,h  

^a NATIONAL INSTITUTE FOR MEDICAL RESEARCH   (United Kingdom)

^b MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF MINHO   (Portugal)

^d Life and Health Sciences Research Institute   (Portugal)

^e TUFTS MEDICAL CENTER   (United States)

^f BENAROYA RESEARCH INSTITUTE   (United States)

^g BAYLOR INSTITUTE FOR IMMUNOLOGY RESEARCH   (United States)

^h NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

INTERFERON; INTERLEUKIN 10; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; TPL 2 PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISEASE EXACERBATION; ENZYME INHIBITION; GENE EXPRESSION REGULATION; GENETICS; HOST RESISTANCE; IMMUNE RESPONSE; IMMUNOREGULATION; IN VIVO STUDY; MACROPHAGE; MICROARRAY ANALYSIS; MOUSE; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; TRANSCRIPTOMICS; TUBERCULOSIS; TUBERCULOSIS CONTROL;

ANIMALS; BACTERIAL LOAD; CYTOKINES; DISEASE RESISTANCE; DOWN-REGULATION; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; INTERFERON TYPE I; INTERLEUKIN-10; LISTERIA MONOCYTOGENES; LISTERIOSIS; MACROPHAGES; MALE; MAP KINASE KINASE KINASES; MAP KINASE SIGNALING SYSTEM; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MONOCYTES; MYCOBACTERIUM TUBERCULOSIS; PROTEIN KINASE INHIBITORS; PROTO-ONCOGENE PROTEINS; TRANSCRIPTION, GENETIC; TUBERCULOSIS;

EID: 84881454396     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1300146     Document Type: Article

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