A nonclinical safety assessment of MnTE-2-PyP, a manganese porphyrin

International Journal of Toxicology

Volumn 32, Issue 4, 2013, Pages 274-287

  Gad, Shayne C ^a   Sullivan, Dexter W ^a   Crapo, James D ^b   Spainhour, Charles B ^c  

^a Gad Consulting Services   (United States)

^b DEPARTMENT OF MEDICINE   (United States)

^c Calvert Laboratories   (United States)

Author keywords

drug; manganese; metalloporphyrin; radiation protection; transplant

Indexed keywords

MANGANESE DERIVATIVE; MANGANESE MESO TETRAKIS(N ETHYLPYRIDIUM 2 YL)PORPHYRIN; PORPHYRIN DERIVATIVE; RADIOPROTECTIVE AGENT; UNCLASSIFIED DRUG;

AREA UNDER THE CURVE; ARTICLE; BREATHING; BREATHING RATE; CARDIOTOXICITY; CELL STRAIN HEK293; CENTRAL NERVOUS SYSTEM; CHROMOSOME ABERRATION; DRUG BLOOD LEVEL; DRUG HALF LIFE; DRUG SAFETY; FEMALE; FLOCCULATION; GENOTOXICITY; HAPLORHINI; HEMOLYSIS; HUMAN; HUMAN TISSUE; IN VITRO STUDY; KIDNEY; LIVER; MALE; MAXIMUM PLASMA CONCENTRATION; MOUSE; NONHUMAN; RABBIT; TIDAL VOLUME;

DRUG; MANGANESE; METALLOPORPHYRIN; RADIATION PROTECTION; TRANSPLANT;

ADMINISTRATION, INTRAVENOUS; ANIMALS; CARDIOVASCULAR SYSTEM; CENTRAL NERVOUS SYSTEM; CHROMOSOME ABERRATIONS; DNA DAMAGE; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG EVALUATION, PRECLINICAL; FEMALE; HEK293 CELLS; HEMOLYSIS; HUMANS; KIDNEY; LIVER; MACACA FASCICULARIS; MALE; METALLOPORPHYRINS; MICE; NO-OBSERVED-ADVERSE-EFFECT LEVEL; RABBITS; RADIATION-PROTECTIVE AGENTS; TOXICITY TESTS;

EID: 84881395873     PISSN: 10915818     EISSN: 1092874X     Source Type: Journal    
DOI: 10.1177/1091581813490203     Document Type: Article

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