Mutation p.S335X in GATA4 reduces its DNA binding affinity and enhances cell apoptosis associated with ventricular septal defect

Current Molecular Medicine

Volumn 13, Issue 6, 2013, Pages 993-999

  Yang, F ^a   Wu, M ^b   Li, Y ^b   Zheng, G Y ^a   Cao, H Q ^a   Sun, W ^b   Yang, R ^b   Zhang, H ^b   Sheng, Y H ^b   Kong, X Q ^b   Tian, X L ^a   Zhou, L ^b  

^a PEKING UNIVERSITY   (China)

^b THE FIRST AFFILIATED HOSPITAL OF NANJING MEDICAL UNIVERSITY   (China)

Author keywords

Apoptosis; Differentiation; DNA binding; GATA4; Ventricular septal defect

Indexed keywords

DNA; TRANSCRIPTION FACTOR GATA 4;

ANIMAL CELL; APOPTOSIS; ARTICLE; BINDING AFFINITY; CELL DIFFERENTIATION; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; GATA4 GENE; GENE; GENE EXPRESSION; GENE MUTATION; HEART MUSCLE CELL; HEART VENTRICLE SEPTUM DEFECT; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IMMUNOCYTOCHEMISTRY; IMMUNOFLUORESCENCE TEST; NICK END LABELING; NONHUMAN; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

EID: 84881347094     PISSN: 15665240     EISSN: 18755666     Source Type: Journal    
DOI: 10.2174/15665240113139990053     Document Type: Article

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