Mutual regioselective inhibition of human UGT1A1-mediated glucuronidation of four flavonoids

Molecular Pharmaceutics

Volumn 10, Issue 8, 2013, Pages 2891-2903

  Ma, Guo ^a   Wu, Baojian ^b   Gao, Song ^b   Yang, Zhen ^b   Ma, Yong ^b   Hu, Ming ^b  

^a FUDAN UNIVERSITY   (China)

^b UNIVERSITY OF HOUSTON   (United States)

Author keywords

flavonoids; glucuronidation; inhibition; regioselective; UGT1A1

Indexed keywords

3 HYDROXYFLAVONE; 3,7,4' TRIHYDROXYFLAVONE; 4' HYDROXYFLAVONE; 7 HYDROXYFLAVONE; FLAVONOID; GLUCURONOSYLTRANSFERASE 1A1; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; CHEMICAL REACTION; CHEMICAL STRUCTURE; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME SUBSTRATE; GLUCURONIDATION; HUMAN; MICHAELIS MENTEN KINETICS; PRIORITY JOURNAL; STEREOCHEMISTRY; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY;

FLAVONOIDS; GLUCURONOSYLTRANSFERASE; HUMANS; INHIBITORY CONCENTRATION 50; KINETICS; MODELS, THEORETICAL; STEREOISOMERISM;

EID: 84881339346     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/mp300599t     Document Type: Article

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