Surface characteristics of spray-dried microspheres consisting of PLGA and PVP: Relating the influence of heat and humidity to the thermal characteristics of these polymers

Molecular Pharmaceutics

Volumn 10, Issue 8, 2013, Pages 3213-3224

  Meeus, Joke ^a   Scurr, David J ^b   Amssoms, Katie ^c   Davies, Martyn C ^b   Roberts, Clive J ^b   Van Den Mooter, Guy ^a  

^a DEPARTMENT OF PHARMACEUTICAL AND PHARMACOLOGICAL SCIENCES   (Belgium)

^b UNIVERSITY OF NOTTINGHAM   (United Kingdom)

^c JOHNSON AND JOHNSON   (United States)

Author keywords

AFM; MDSC; microspheres; parenteral controlled release; PLGA; PVP; surface analysis; ToF SIMS; XPS

Indexed keywords

MICROSPHERE; POLYGLACTIN; POLYMER; POVIDONE;

ARTICLE; ATOMIC FORCE MICROSCOPY; CALORIMETER; DIFFERENTIAL SCANNING CALORIMETRY; EQUIPMENT; HEAT; HUMIDITY; MODULATED DIFFERENTIAL SCANNING CALORIMETRY; MORPHOLOGY; PARTICLE SIZE; PHYSICAL CHEMISTRY; POLYMERIZATION; PRIORITY JOURNAL; SCANNING ELECTRON MICROSCOPE; SCANNING ELECTRON MICROSCOPY; SPRAY DRYING; SURFACE PROPERTY; TEMPERATURE; THERMAL ANALYSIS; TIME OF FLIGHT MASS SPECTROMETRY; X RAY PHOTOELECTRON SPECTROSCOPY;

HOT TEMPERATURE; HUMIDITY; LACTIC ACID; MICROSCOPY, ATOMIC FORCE; MICROSPHERES; POLYGLYCOLIC ACID; POLYMERS; POVIDONE;

EID: 84881326928     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/mp400263d     Document Type: Article

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