Controlling the diameter, monodispersity, and solubility of ApoA1 nanolipoprotein particles using telodendrimer chemistry

Protein Science

Volumn 22, Issue 8, 2013, Pages 1078-1086

  Hi, Wei ^a,b   Luo, Juntao ^c   Bourguet, Feliza ^d   Xing, Li ^e   Yi, Sun K ^b   Gao, Tingjuan ^a   Blanchette, Craig ^d   Henderson, Paul T ^b   Kuhn, Edward ^d   Malfatti, Mike ^d   Murphy, William J ^b   Cheng, R Holland ^e   Lam, Kit S ^b   Coleman, Matthew A ^a,b,d  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c State University of New York Upstate Medical University: College of Medicine   (United States)

^d LAWRENCE LIVERMORE NATIONAL LABORATORY   (United States)

^e UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Apolipoprotein; Cell free expression; Membrane protein; Mono dispersity; Nanolipoproteins; Nanotechnology; Telodendrimer

Indexed keywords

APOLIPOPROTEIN A1; CHOLIC ACID; DENDRIMER; LYSINE; MACROGOL; POLYMER; TELODENDRIMER; UNCLASSIFIED DRUG;

AQUEOUS SOLUTION; ARTICLE; FLUORESCENCE CORRELATION SPECTROSCOPY; LIGHT SCATTERING; PHOSPHOLIPID BILAYER; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN PURIFICATION; PROTEIN SYNTHESIS; SOLUBILITY; TRANSMISSION ELECTRON MICROSCOPY;

APOLIPOPROTEIN; CELL-FREE EXPRESSION; MEMBRANE PROTEIN; MONO-DISPERSITY; NANOLIPOPROTEINS; NANOTECHNOLOGY; TELODENDRIMER;

APOLIPOPROTEIN A-I; CELL-FREE SYSTEM; CRYOELECTRON MICROSCOPY; DENDRIMERS; MEMBRANE PROTEINS; NANOPARTICLES; PROTEIN ENGINEERING; SPECTROMETRY, FLUORESCENCE;

EID: 84881302278     PISSN: 09618368     EISSN: 1469896X     Source Type: Journal    
DOI: 10.1002/pro.2292     Document Type: Article

References (31)

1. Jonas A (1986) Reconstitution of high-density lipoproteins. Methods Enzymol 128:553-582.
2. Bayburt TH, Grinkova YV, Sligar SG (2002) Selfassembly of discoidal phospholipid bilayer nanoparticles with membrane scaffold proteins. Nano Lett 2: 853-856.
3. Chromy BA, Arroyo E, Blanchette CD, Bench G, Benner H, Cappuccio JA, Coleman MA, Henderson PT, Hinz AK, Kuhn EA, Pesavento JB, Segelke BW, Sulchek TA, Tarasow T, Walsworth VL, Hoeprich PD. (2007) Different apolipoproteins impact nanolipoprotein particle formation. J Am Chem Soc 129:14348-14354.
4. Sunahara H, Urano Y, Kojima H, Nagano T (2007) Design and synthesis of a library of BODIPY-based environmental polarity sensors utilizing photoinduced electron-transfer-controlled fluorescence ON/OFF switching. J Am Chem Soc 129:5597-5604.
5. Nath A, Atkins WM, Sligar SG (2007) Applications of phospholipid bilayer nanodiscs in the study of membranes and membrane proteins. Biochemistry 46: 2059-2069.
6. Blanchette CD, Law RW, Benner H, Pesavento B, Cappuccio JA, Walsworth V, Kuhn EA, Corzett M, Chromy BA, Segelke BW, Coleman MA, Bench G, Hoeprich PD, Sulchek TA (2009) Quantifying size distributions of nanolipoprotein particles with single-particle analysis and molecular dynamic simulations. J Lipid Res 49:1420.
7. Blanchette CD, Fischer NO, Corzett M, Bench G, Hoeprich PD (2010) Kinetic analysis of his-tagged protein binding to nickel-chelating nanolipoprotein particles. Bioconjug Chem 21:1321-1330.
8. Ryan RO (2008) Nanodisks: hydrophobic drug delivery vehicles. Expert Opin Drug Deliv 5:343-351.
9. Ryan RO (2010) Nanobiotechnology applications of reconstituted high density lipoprotein. J Nanobiotech 8-28.
10. Bayburt TH, Grinkova YV, Sligar SG (2006) Assembly of single bacteriorhodopsin trimers in bilayer nanodiscs. Arch Biochem Biophys 450:215-222.
11. Whorton MR, Bokoch MP, Rasmussen SGF, Huang B, Zare RN, Kobilka B, Sunahara RK. (2007) Monomeric G protein-coupled receptor isolated in a high-density lipo-protein particle efficiently activates its G protein. Proc Natl Acad Sci U S A 104:7682-7687.
12. Cappuccio JA, Blanchette CD, Sulchek TA, Arroyo ES, Kralj JM, Hinz AK, Kuhn EA, Chromy BA, Segelke BW, Rothschild KJ, Fletcher JE, Katzen F, Peterson TC, Kudlicki WA, Bench G, Hoeprich PD, Coleman M.A. (2008) Cell-free co-expression of functional membrane proteins and apolipoprotein, forming soluble nanolipoprotein particles. Mol Cell Proteomics 7: 2246-2253.
13. Baker SE, Hopkins RC, Blanchette CD, Walsworth VL, Sumbad R, Fischer NO, Kuhn EA, Coleman M, Chromy BA, Letant SE, Hoeprich PD, Adams MW, Henderson PT. (2009) Hydrogen production by a hyperthermophilic membrane-bound hydrogenase in watersoluble nanolipoprotein particles. J Am Chem Soc 131: 7508-7509.
14. Gao T, Blanchette CD, He W, Bourguet F, Ly S, Katzen F, Kudlicki WA, Henderson PT, Laurence TA, Huser T, Coleman M.A. (2011) Characterizing diffusion dynamics of a membrane protein associated with nanolipoproteins using fluorescence correlation spectroscopy. Prot Sci 20:437-447.
15. Katzen F, Fletcher JE, Yang J, Kang D, Peterson TC, Cappuccio JA, Blanchette CD, Sulchek T, Chromy BA, Hoeprich PD, Coleman MA, Kudlicki W. (2008) Insertion of membrane proteins into discoidal membranes using a cell-free protein expression approach. J Proteome Res 7:3535-3542.
16. Rensen PC, Schiffelers RM, Versluis AJ, Bijsterbosch MK, Van Kuijk-Meuwissen ME, Van Berkel TJ. (1997) Human recombinant apolipoprotein E-enriched liposomes can mimic low-density lipoproteins as carriers for the site-specific delivery of antitumor agents. Mol Pharmacol 52:445-455.
17. Coleman MA, Lao VH, Segelke BW, Beernink PT (2004) High-throughput, fluorescence-based screening for soluble protein expression. J Proteome Res 3:1024-1032.
18. Kigawa T, Yabuki T, Yoshida Y, Tsutsui M, Ito Y, Shibata T, Yokoyama S. (1999) Cell-free production and stable-isotope labeling of milligram quantities of proteins. FEBS Lett 442:15-19.
19. Doi N, Takashima H, Kinjo M, Sakata K, Kawahashi Y, Oishi Y, Oyama R, Miyamoto-Sato E, Sawasaki T, Endo Y, Yanagawa H. (2002) Novel fluorescence labeling and high-throughput assay technologies for in vitro analysis of protein interactions. Genome Res 12: 487-492.
20. Yang JP, Cirico T, Katzen F, Peterson TC, Kudlicki W (2011) Cell-free synthesis of a functional G proteincoupled receptor complexed with nanometer scale bilayer discs. BMC Biotechnol 11:57.
21. Keppetipola S, Kudlicki W, Nguyen BD, Meng X, Donovan KJ, Shaka AJ (2006) From gene to HSQC in under five hours: high-throughput NMR proteomics. J Am Chem Soc 128:4508-4509.
22. Frydman J, Hartl FU (1996) Principles of chaperoneassisted protein folding: differences between in vitro and in vivo mechanisms. Science 272:1497-1502.
23. Klammt C, Schwarz D, Fendler K, Haase W, Dotsch V, Bernhard F (2005) Evaluation of detergents for the soluble expression of alpha-helical and beta-barrel-type integral membrane proteins by a preparative scale individual cell-free expression system. FEBS J 272: 6024-6038.
24. Jewett MC, Swartz JR (2004) Rapid expression and purification of 100 nmol quantities of active protein using cell-free protein synthesis. Biotechnol Prog 20: 102-109.
25. Mori M, Miura S, Tatibana M, Cohen PP (1979) Cellfree synthesis and processing of a putative precursor for mitochondrial carbamyl phosphate synthetase I of rat liver. Proc Natl Acad Sci U S A 76:5071-5075.
26. Bayburt TH, Leitz AJ, Xie G, Oprian DD, Sligar SG (2007) Transducin activation by nanoscale lipid bilayers containing one and two rhodopsins. J Biol Chem 282:14875-14881.
27. Luo J, Xiao K, Li Y, Lee JS, Shi L, Tan YH, Xing L, Holland Cheng R, Liu GY, Lam KS. (2010) Well-defined, size-tunable, multifunctional micelles for efficient paclitaxel delivery for cancer treatment. Bioconjug Chem 21: 1216-1212.
28. Xiao K, Luo J, Fowler WL, Li Y, Lee JS, Xing L, Cheng RH, Wang L, Lam KS. (2009) A self-assembling nanoparticle for paclitaxel delivery in ovarian cancer. Biomaterials 30:6006-6016.
29. Rosenow MA, Magee CL, Williams JC, Allen JP (2002) The influence of detergents on the solubility of membrane proteins. Acta Cryst D58:2076-2081.
30. Zhang Q, Ma X, Ward A, Hong WX, Jaakola VP, Stevens RC, Finn MG, Chang G (2007) Designing facial amphiphiles for the stabilization of integral membrane proteins. Angew Chem Int Ed Engl 46: 7023-7025.
31. Charvolin D, Perez JB, Rouviere F, Giusti F, Bazzacco P, Abdine A, Rappaport F, Martinez KL, Popot JL (2009) The use of amphipols as universal molecular adapters to immobilize membrane proteins onto solid supports. Proc Natl Acad Sci. 106:405-410.