-
1
-
-
84855792427
-
Cancer statistics 2012
-
Siegel R, Naishadham D, Jemal A. Cancer statistics, 2012. CA Cancer J. Clin. 62(1), 10-29 (2012
-
(2012)
CA Cancer J. Clin
, vol.62
, Issue.1
, pp. 10-29
-
-
Siegel, R.1
Naishadham, D.2
Jemal, A.3
-
2
-
-
0030049697
-
Phase II study of gemcitabine in patients with advanced pancreatic cancer
-
Carmichael J, Fink U, Russell RC et al. Phase II study of gemcitabine in patients with advanced pancreatic cancer. Br. J. Cancer 73(1), 101-105 (1996
-
(1996)
Br. J. Cancer
, vol.73
, Issue.1
, pp. 101-105
-
-
Carmichael, J.1
Fink, U.2
Russell, R.C.3
-
3
-
-
0028292341
-
Phase II trial of gemcitabine (2,2'-difluorodeoxycytidine) in patients with adenocarcinoma of the pancreas
-
Casper ES, Green MR, Kelsen DP et al. Phase II trial of gemcitabine (2,2'-difluorodeoxycytidine) in patients with adenocarcinoma of the pancreas. Invest. New Drugs 12(1), 29-34 (1994
-
(1994)
Invest. New Drugs
, vol.12
, Issue.1
, pp. 29-34
-
-
Casper, E.S.1
Green, M.R.2
Kelsen, D.P.3
-
4
-
-
77956416112
-
Adjuvant chemotherapy with fluorouracil plus folinic acid vs gemcitabine following pancreatic cancer resection: A randomized controlled trial
-
Neoptolemos JP, Stocken DD, Bassi C et al. Adjuvant chemotherapy with fluorouracil plus folinic acid vs gemcitabine following pancreatic cancer resection: A randomized controlled trial. JAMA 304(10), 1073-1081 (2010
-
(2010)
JAMA
, vol.304
, Issue.10
, pp. 1073-1081
-
-
Neoptolemos, J.P.1
Stocken, D.D.2
Bassi, C.3
-
5
-
-
33846405332
-
Adjuvant chemotherapy with gemcitabine vs observation in patients undergoing curative-intent resection of pancreatic cancer: A randomized controlled trial
-
Oettle H, Post S, Neuhaus P et al. Adjuvant chemotherapy with gemcitabine vs observation in patients undergoing curative-intent resection of pancreatic cancer: A randomized controlled trial. JAMA 297(3), 267-277 (2007
-
(2007)
JAMA
, vol.297
, Issue.3
, pp. 267-277
-
-
Oettle, H.1
Post, S.2
Neuhaus, P.3
-
7
-
-
35848960127
-
Review of recent studies on resistance to cytotoxic deoxynucleoside analogues
-
Jordheim LP, Dumontet C. Review of recent studies on resistance to cytotoxic deoxynucleoside analogues. Biochim. Biophys. Acta 1776(2), 138-159 (2007
-
(2007)
Biochim. Biophys. Acta
, vol.1776
, Issue.2
, pp. 138-159
-
-
Jordheim, L.P.1
Dumontet, C.2
-
8
-
-
84859580551
-
Overcoming nucleoside analog chemoresistance of pancreatic cancer: A therapeutic challenge
-
Hung SW, Mody HR, Govindarajan R. Overcoming nucleoside analog chemoresistance of pancreatic cancer: A therapeutic challenge. Cancer Lett. 320(2), 138-149 (2012
-
(2012)
Cancer Lett
, vol.320
, Issue.2
, pp. 138-149
-
-
Hung, S.W.1
Mody, H.R.2
Govindarajan, R.3
-
9
-
-
84860743457
-
Molecular predictors of gemcitabine response in pancreatic cancer
-
Voutsadakis IA. Molecular predictors of gemcitabine response in pancreatic cancer. World J. Gastrointest. Oncol. 3(11), 153-164 (2011
-
(2011)
World J. Gastrointest. Oncol
, vol.3
, Issue.11
, pp. 153-164
-
-
Voutsadakis, I.A.1
-
10
-
-
0033520708
-
Gemcitabine transport in xenopus oocytes expressing recombinant plasma membrane mammalian nucleoside transporters
-
Mackey JR, Yao SY, Smith KM et al. Gemcitabine transport in xenopus oocytes expressing recombinant plasma membrane mammalian nucleoside transporters. J. Natl Cancer Inst. 91(21), 1876-1881 (1999
-
(1999)
J. Natl Cancer Inst
, vol.91
, Issue.21
, pp. 1876-1881
-
-
Mackey, J.R.1
Yao, S.Y.2
Smith, K.M.3
-
11
-
-
0025049372
-
Inhibition of ribonucleotide reduction in CCRF-CEM cells by 2',2'-difluorodeoxycytidine
-
Heinemann V, Xu YZ, Chubb S et al. Inhibition of ribonucleotide reduction in CCRF-CEM cells by 2',2'-difluorodeoxycytidine. Mol. Pharmacol. 38(4), 567-572 (1990
-
(1990)
Mol. Pharmacol
, vol.38
, Issue.4
, pp. 567-572
-
-
Heinemann, V.1
Xu, Y.Z.2
Chubb, S.3
-
12
-
-
84863836775
-
Human equilibrative nucleoside transporter 1 expression predicts survival of advanced cholangiocarcinoma patients treated with gemcitabine-based adjuvant chemotherapy after surgical resection
-
Kobayashi H, Murakami Y, Uemura K et al. Human equilibrative nucleoside transporter 1 expression predicts survival of advanced cholangiocarcinoma patients treated with gemcitabine-based adjuvant chemotherapy after surgical resection. Ann. Surg. 256(2), 288-296 (2012
-
(2012)
Ann. Surg
, vol.256
, Issue.2
, pp. 288-296
-
-
Kobayashi, H.1
Murakami, Y.2
Uemura, K.3
-
13
-
-
34548203759
-
The absence of human equilibrative nucleoside transporter 1 expression predicts nonresponse to gemcitabine-containing chemotherapy in non-small cell lung cancer
-
Oguri T, Achiwa H, Muramatsu H et al. The absence of human equilibrative nucleoside transporter 1 expression predicts nonresponse to gemcitabine- containing chemotherapy in non-small cell lung cancer. Cancer Lett. 256(1), 112-119 (2007
-
(2007)
Cancer Lett
, vol.256
, Issue.1
, pp. 112-119
-
-
Oguri, T.1
Achiwa, H.2
Muramatsu, H.3
-
14
-
-
79959548041
-
The ribonucleotide reductase large subunit (RRM1) as a predictive factor in patients with cancer
-
Jordheim LP, Seve P, Tredan O, Dumontet C. The ribonucleotide reductase large subunit (RRM1) as a predictive factor in patients with cancer. Lancet Oncol. 12(7), 693-702 (2011
-
(2011)
Lancet Oncol
, vol.12
, Issue.7
, pp. 693-702
-
-
Jordheim, L.P.1
Seve, P.2
Tredan, O.3
Dumontet, C.4
-
15
-
-
33846958737
-
Involvement of ribonucleotide reductase M1 subunit overexpression in gemcitabine resistance of human pancreatic cancer
-
Nakahira S, Nakamori S, Tsujie M et al. Involvement of ribonucleotide reductase M1 subunit overexpression in gemcitabine resistance of human pancreatic cancer. Int. J. Cancer 120(6), 1355-1363 (2007
-
(2007)
Int. J. Cancer
, vol.120
, Issue.6
, pp. 1355-1363
-
-
Nakahira, S.1
Nakamori, S.2
Tsujie, M.3
-
16
-
-
49049100257
-
Down-regulation of deoxycytidine kinase enhances acquired resistance to gemcitabine in pancreatic cancer
-
Ohhashi S, Ohuchida K, Mizumoto K et al. Down-regulation of deoxycytidine kinase enhances acquired resistance to gemcitabine in pancreatic cancer. Anticancer Res. 28(4B), 2205-2212 (2008
-
(2008)
Anticancer Res
, vol.28
, Issue.4 B
, pp. 2205-2212
-
-
Ohhashi, S.1
Ohuchida, K.2
Mizumoto, K.3
-
17
-
-
79959992295
-
Predicting the chemosensitivity of pancreatic cancer cells by quantifying the expression levels of genes associated with the metabolism of gemcitabine and 5-fluorouracil
-
Kurata N, Fujita H, Ohuchida K et al. Predicting the chemosensitivity of pancreatic cancer cells by quantifying the expression levels of genes associated with the metabolism of gemcitabine and 5-fluorouracil. Int. J. Oncol. 39(2), 473-482 (2011
-
(2011)
Int. J. Oncol
, vol.39
, Issue.2
, pp. 473-482
-
-
Kurata, N.1
Fujita, H.2
Ohuchida, K.3
-
18
-
-
71349084183
-
Predicting gemcitabine transport and toxicity in human pancreatic cancer cell lines with the positron emission tomography tracer 3'-deoxy-3'- fluorothymidine
-
Paproski RJ, Young JD, Cass CE. Predicting gemcitabine transport and toxicity in human pancreatic cancer cell lines with the positron emission tomography tracer 3'-deoxy-3'-fluorothymidine. Biochem. Pharmacol. 79(4), 587-595 (2010
-
(2010)
Biochem. Pharmacol
, vol.79
, Issue.4
, pp. 587-595
-
-
Paproski, R.J.1
Young, J.D.2
Cass, C.E.3
-
19
-
-
46649083576
-
Adenoviral-mediated overexpression of human equilibrative nucleoside transporter 1 (hENT1) enhances gemcitabine response in human pancreatic cancer
-
Perez-Torras S, Garcia-Manteiga J, Mercade E et al. Adenoviral-mediated overexpression of human equilibrative nucleoside transporter 1 (hENT1) enhances gemcitabine response in human pancreatic cancer. Biochem. Pharmacol. 76(3), 322-329 (2008
-
(2008)
Biochem. Pharmacol
, vol.76
, Issue.3
, pp. 322-329
-
-
Perez-Torras, S.1
Garcia-Manteiga, J.2
Mercade, E.3
-
20
-
-
67650485895
-
Gemcitabine-based chemogene therapy for pancreatic cancer using Ad-dCK:UMK GDEPT and TS/RR siRNA strategies
-
Réjiba S, Bigand C, Parmentier C, Hajri A. Gemcitabine-based chemogene therapy for pancreatic cancer using Ad-dCK:UMK GDEPT and TS/RR siRNA strategies. Neoplasia 11(7), 637-650 (2009
-
(2009)
Neoplasia
, vol.11
, Issue.7
, pp. 637-650
-
-
Réjiba, S.1
Bigand, C.2
Parmentier, C.3
Hajri, A.4
-
21
-
-
33846816556
-
Gemcitabine chemoresistance and molecular markers associated with gemcitabine transport and metabolism in human pancreatic cancer cells
-
Nakano Y, Tanno S, Koizumi K et al. Gemcitabine chemoresistance and molecular markers associated with gemcitabine transport and metabolism in human pancreatic cancer cells. Br. J. Cancer 96(3), 457-463 (2007
-
(2007)
Br. J. Cancer
, vol.96
, Issue.3
, pp. 457-463
-
-
Nakano, Y.1
Tanno, S.2
Koizumi, K.3
-
22
-
-
40549099699
-
Pretreatment with S 1, an oral derivative of 5-fluorouracil, enhances gemcitabine effects in pancreatic cancer xenografts
-
Nakahira S, Nakamori S, Tsujie M et al. Pretreatment with S 1, an oral derivative of 5-fluorouracil, enhances gemcitabine effects in pancreatic cancer xenografts. Anticancer Res. 28(1A), 179-186 (2008
-
(2008)
Anticancer Res
, vol.28
, Issue.1 A
, pp. 179-186
-
-
Nakahira, S.1
Nakamori, S.2
Tsujie, M.3
-
23
-
-
80054749399
-
Enhanced efficacy of gemcitabine by indole-3-carbinol in pancreatic cell lines: The role of human equilibrative nucleoside transporter 1
-
Wang H, Word BR, Lyn-Cook BD. Enhanced efficacy of gemcitabine by indole-3-carbinol in pancreatic cell lines: The role of human equilibrative nucleoside transporter 1. Anticancer Res. 31(10), 3171-3180 (2011
-
(2011)
Anticancer Res
, vol.3110
, pp. 3171-3180
-
-
Wang, H.1
Word, B.R.2
Lyn-Cook, B.D.3
-
24
-
-
84864883108
-
Molecular mechanisms involved in the synergistic interaction of the EZH2 inhibitor 3-deazaneplanocin A with gemcitabine in pancreatic cancer cells
-
Avan A, Crea F, Paolicchi E et al. Molecular mechanisms involved in the synergistic interaction of the EZH2 inhibitor 3-deazaneplanocin A with gemcitabine in pancreatic cancer cells. Mol. Cancer Ther. 11(8), 1735-1746 (2012
-
(2012)
Mol. Cancer Ther
, vol.11
, Issue.8
, pp. 1735-1746
-
-
Avan, A.1
Crea, F.2
Paolicchi, E.3
-
25
-
-
78651094422
-
Imexon enhances gemcitabine cytotoxicity by inhibition of ribonucleotide reductase
-
Roman NO, Samulitis BK, Wisner L, Landowski TH, Dorr RT. Imexon enhances gemcitabine cytotoxicity by inhibition of ribonucleotide reductase. Cancer Chemother. Pharmacol. 67(1), 183-192 (2011
-
(2011)
Cancer Chemother. Pharmacol
, vol.67
, Issue.1
, pp. 183-192
-
-
Roman, N.O.1
Samulitis, B.K.2
Wisner, L.3
Landowski, T.H.4
Dorr, R.T.5
-
26
-
-
75449107159
-
Tranilast strongly sensitizes pancreatic cancer cells to gemcitabine via decreasing protein expression of ribonucleotide reductase 1
-
Mitsuno M, Kitajima Y, Ohtaka K et al. Tranilast strongly sensitizes pancreatic cancer cells to gemcitabine via decreasing protein expression of ribonucleotide reductase 1. Int. J. Oncol. 36(2), 341-349 (2010
-
(2010)
Int. J. Oncol
, vol.36
, Issue.2
, pp. 341-349
-
-
Mitsuno, M.1
Kitajima, Y.2
Ohtaka, K.3
-
27
-
-
80052707802
-
Critical role of laser microdissection for genetic, epigenetic and proteomic analyses in pancreatic cancer
-
Funel N, Giovannetti E, Pollina LE et al. Critical role of laser microdissection for genetic, epigenetic and proteomic analyses in pancreatic cancer. Expert Rev. Mol. Diagn. 11(7), 695-701 (2011
-
(2011)
Expert Rev. Mol. Diagn
, vol.11
, Issue.7
, pp. 695-701
-
-
Funel, N.1
Giovannetti, E.2
Pollina, L.E.3
-
28
-
-
84872173257
-
Human equilibrative nucleoside transporter 1 level does not predict prognosis in pancreatic cancer patients treated with neoadjuvant chemoradiation including gemcitabine
-
Kawada N, Uehara H, Katayama K et al. Human equilibrative nucleoside transporter 1 level does not predict prognosis in pancreatic cancer patients treated with neoadjuvant chemoradiation including gemcitabine. J. Hepatobiliary Pancreat. Sci. 19(6), 717-722 (2012
-
(2012)
J. Hepatobiliary Pancreat. Sci
, vol.19
, Issue.6
, pp. 717-722
-
-
Kawada, N.1
Uehara, H.2
Katayama, K.3
-
29
-
-
68149107766
-
Gemcitabine sensitivity-related mRNA expression in endoscopic ultrasound-guided fine-needle aspiration biopsy of unresectable pancreatic cancer
-
Ashida R, Nakata B, Shigekawa M et al. Gemcitabine sensitivity-related mRNA expression in endoscopic ultrasound-guided fine-needle aspiration biopsy of unresectable pancreatic cancer. J. Exp. Clin. Cancer Res. 28, 83 (2009
-
(2009)
J. Exp. Clin. Cancer Res
, vol.28
, pp. 83
-
-
Ashida, R.1
Nakata, B.2
Shigekawa, M.3
-
30
-
-
84872806569
-
Predictive and prognostic roles of ribonucleotide reductase M1 in resectable pancreatic adenocarcinoma
-
Xie H, Jiang W, Jiang J et al. Predictive and prognostic roles of ribonucleotide reductase M1 in resectable pancreatic adenocarcinoma. Cancer 119(1), 173-181 (2013
-
(2013)
Cancer
, vol.119
, Issue.1
, pp. 173-181
-
-
Xie, H.1
Jiang, W.2
Jiang, J.3
-
31
-
-
68949154477
-
Significance of RRM1 and ERCC1 expression in resectable pancreatic adenocarcinoma
-
Akita H, Zheng Z, Takeda Y et al. Significance of RRM1 and ERCC1 expression in resectable pancreatic adenocarcinoma. Oncogene 28(32), 2903-2909 (2009
-
(2009)
Oncogene
, vol.28
, Issue.32
, pp. 2903-2909
-
-
Akita, H.1
Zheng, Z.2
Takeda, Y.3
-
32
-
-
84865474189
-
Levels of gemcitabine transport and metabolism proteins predict survival times of patients treated with gemcitabine for pancreatic adenocarcinoma
-
Marechal R, Bachet JB, Mackey JR et al. Levels of gemcitabine transport and metabolism proteins predict survival times of patients treated with gemcitabine for pancreatic adenocarcinoma. Gastroenterology 143(3), 664-674 (2012
-
(2012)
Gastroenterology
, vol.143
, Issue.3
, pp. 664-674
-
-
Marechal, R.1
Bachet, J.B.2
Mackey, J.R.3
-
33
-
-
84875222769
-
Combined analysis of intratumoral human equilibrative nucleoside transporter 1 (hENT1) and ribonucleotide reductase regulatory subunit M1 (RRM1) expression is a powerful predictor of survival in patients with pancreatic carcinoma treated with adjuvant gemcitabine-based chemotherapy after operative resection
-
Nakagawa N, Murakami Y, Uemura K et al. Combined analysis of intratumoral human equilibrative nucleoside transporter 1 (hENT1) and ribonucleotide reductase regulatory subunit M1 (RRM1) expression is a powerful predictor of survival in patients with pancreatic carcinoma treated with adjuvant gemcitabine-based chemotherapy after operative resection. Surgery 153(4), 565-575 (2013
-
(2013)
Surgery
, vol.153
, Issue.4
, pp. 565-575
-
-
Nakagawa, N.1
Murakami, Y.2
Uemura, K.3
-
34
-
-
77957814960
-
Gene expression levels as predictive markers of outcome in pancreatic cancer after gemcitabine-based adjuvant chemotherapy
-
Fujita H, Ohuchida K, Mizumoto K et al. Gene expression levels as predictive markers of outcome in pancreatic cancer after gemcitabine-based adjuvant chemotherapy. Neoplasia 12(10), 807-817 (2010
-
(2010)
Neoplasia
, vol.12
, Issue.10
, pp. 807-817
-
-
Fujita, H.1
Ohuchida, K.2
Mizumoto, K.3
-
35
-
-
33646407273
-
Immunohistochemical and genetic evaluation of deoxycytidine kinase in pancreatic cancer: Relationship to molecular mechanisms of gemcitabine resistance and survival
-
Sebastiani V, Ricci F, Rubio-Viquiera B et al. Immunohistochemical and genetic evaluation of deoxycytidine kinase in pancreatic cancer: Relationship to molecular mechanisms of gemcitabine resistance and survival. Clin. Cancer Res. 12(8), 2492-2497 (2006
-
(2006)
Clin. Cancer Res
, vol.12
, Issue.8
, pp. 2492-2497
-
-
Sebastiani, V.1
Ricci, F.2
Rubio-Viquiera, B.3
-
36
-
-
78449295201
-
Deoxycitidine kinase is associated with prolonged survival after adjuvant gemcitabine for resected pancreatic adenocarcinoma
-
Marechal R, Mackey JR, Lai R et al. Deoxycitidine kinase is associated with prolonged survival after adjuvant gemcitabine for resected pancreatic adenocarcinoma. Cancer 116(22), 5200-5206 (2010
-
(2010)
Cancer
, vol.116
, Issue.22
, pp. 5200-5206
-
-
Marechal, R.1
Mackey, J.R.2
Lai, R.3
-
37
-
-
58149096305
-
CP-4055 and CP-4126 are active in ara-C and gemcitabine-resistant lymphoma cell lines
-
Galmarini CM, Myhren F, Sandvold ML. CP-4055 and CP-4126 are active in ara-C and gemcitabine-resistant lymphoma cell lines. Br. J. Haematol. 144(2), 273-275 (2009
-
(2009)
Br. J. Haematol
, vol.144
, Issue.2
, pp. 273-275
-
-
Galmarini, C.M.1
Myhren, F.2
Sandvold, M.L.3
-
38
-
-
0142219312
-
Nucleoside transporter profiles in human pancreatic cancer cells: Role of hCNT1 in 2',2'-difluorodeoxycytidine-induced cytotoxicity
-
García-Manteiga J, Molina-Arcas M, Casado FJ, Mazo A, Pastor-Anglada M. Nucleoside transporter profiles in human pancreatic cancer cells: Role of hCNT1 in 2',2'-difluorodeoxycytidine-induced cytotoxicity. Clin. Cancer Res. 9(13), 5000-5008 (2003
-
(2003)
Clin. Cancer Res
, vol.9
, Issue.13
, pp. 5000-5008
-
-
García-Manteiga, J.1
Molina-Arcas, M.2
Casado, F.J.3
Mazo, A.4
Pastor-Anglada, M.5
-
39
-
-
65349163336
-
Human equilibrative nucleoside transporter 1 and human concentrative nucleoside transporter 3 predict survival after adjuvant gemcitabine therapy in resected pancreatic adenocarcinoma
-
Marechal R, Mackey JR, Lai R et al. Human equilibrative nucleoside transporter 1 and human concentrative nucleoside transporter 3 predict survival after adjuvant gemcitabine therapy in resected pancreatic adenocarcinoma. Clin. Cancer Res. 15(8), 2913-2919 (2009
-
(2009)
Clin. Cancer Res
, vol.15
, Issue.8
, pp. 2913-2919
-
-
Marechal, R.1
Mackey, J.R.2
Lai, R.3
-
40
-
-
82255175232
-
Squalenoyl gemcitabine nanomedicine overcomes the low efficacy of gemcitabine therapy in pancreatic cancer
-
Réjiba S, Reddy LH, Bigand C, Parmentier C, Couvreur P, Hajri A. Squalenoyl gemcitabine nanomedicine overcomes the low efficacy of gemcitabine therapy in pancreatic cancer. Nanomedicine 7(6), 841-849 (2011
-
(2011)
Nanomedicine
, vol.7
, Issue.6
, pp. 841-849
-
-
Réjiba, S.1
Reddy, L.H.2
Bigand, C.3
Parmentier, C.4
Couvreur, P.5
Hajri, A.6
-
41
-
-
80053988999
-
Interaction of an amphiphilic squalenoyl prodrug of gemcitabine with cellular membranes
-
Bildstein L, Pili B, Marsaud V et al. Interaction of an amphiphilic squalenoyl prodrug of gemcitabine with cellular membranes. Eur. J. Pharm. Biopharm. 79(3), 612-620 (2011
-
(2011)
Eur. J. Pharm. Biopharm
, vol.79
, Issue.3
, pp. 612-620
-
-
Bildstein, L.1
Pili, B.2
Marsaud, V.3
-
42
-
-
4143111313
-
Characterization of a gemcitabine-resistant murine leukemic cell line: Reversion of in vitro resistance by a mononucleotide prodrug
-
Jordheim LP, Cros E, Gouy MH et al. Characterization of a gemcitabine-resistant murine leukemic cell line: Reversion of in vitro resistance by a mononucleotide prodrug. Clin. Cancer Res. 10(16), 5614-5621 (2004
-
(2004)
Clin. Cancer Res
, vol.10
, Issue.16
, pp. 5614-5621
-
-
Jordheim, L.P.1
Cros, E.2
Gouy, M.H.3
-
43
-
-
68649114340
-
Special feature of mixed phosphotriester derivatives of cytarabine
-
Gouy MH, Jordheim LP, Lefebvre I et al. Special feature of mixed phosphotriester derivatives of cytarabine. Bioorg. Med. Chem. 17(17), 6340-6347 (2009
-
(2009)
Bioorg. Med. Chem
, vol.17
, Issue.17
, pp. 6340-6347
-
-
Gouy, M.H.1
Jordheim, L.P.2
Lefebvre, I.3
-
44
-
-
34547602969
-
Synthesis and biological activity of a gemcitabine phosphoramidate prodrug
-
Wu W, Sigmond J, Peters GJ, Borch RF. Synthesis and biological activity of a gemcitabine phosphoramidate prodrug. J. Med. Chem. 50(15), 3743-3746 (2007
-
(2007)
J. Med. Chem
, vol.50
, Issue.15
, pp. 3743-3746
-
-
Wu, W.1
Sigmond, J.2
Peters, G.J.3
Borch, R.F.4
-
45
-
-
79960006148
-
Systematic review of immunohistochemical biomarkers to identify prognostic subgroups of patients with pancreatic cancer
-
Ansari D, Rosendahl A, Elebro J, Andersson R. Systematic review of immunohistochemical biomarkers to identify prognostic subgroups of patients with pancreatic cancer. Br. J. Surg. 98(8), 1041-1055 (2011
-
(2011)
Br. J. Surg
, vol.98
, Issue.8
, pp. 1041-1055
-
-
Ansari, D.1
Rosendahl, A.2
Elebro, J.3
Andersson, R.4
-
46
-
-
84871298277
-
Diagnostic, prognostic, and predictive biomarkers in pancreatic cancer
-
Winter JM, Yeo CJ, Brody Jr. Diagnostic, prognostic, and predictive biomarkers in pancreatic cancer. J. Surg. Oncol. 107(1), 15-22 (2013
-
(2013)
J. Surg. Oncol
, vol.107
, Issue.1
, pp. 15-22
-
-
Winter, J.M.1
Yeo, C.J.2
Brody, J.R.3
-
47
-
-
34447567414
-
Feasibility and efficacy of molecular analysis-directed individualized therapy in advanced non-small-cell lung cancer
-
Simon G, Sharma A, Li X et al. Feasibility and efficacy of molecular analysis-directed individualized therapy in advanced non-small-cell lung cancer. J. Clin. Oncol. 25(19), 2741-2746 (2007
-
(2007)
J. Clin. Oncol
, vol.25
, Issue.19
, pp. 2741-2746
-
-
Simon, G.1
Sharma, A.2
Li, X.3
-
48
-
-
84859796195
-
Preliminary indication of survival benefit from ERCC1 and RRM1-Tailored chemotherapy in patients with advanced nonsmall cell lung cancer: Evidence from an individual patient analysis
-
Simon GR, Schell MJ, Begum M et al. Preliminary indication of survival benefit from ERCC1 and RRM1-Tailored chemotherapy in patients with advanced nonsmall cell lung cancer: Evidence from an individual patient analysis. Cancer 118(9), 2525-2531 (2012
-
(2012)
Cancer
, vol.118
, Issue.9
, pp. 2525-2531
-
-
Simon, G.R.1
Schell, M.J.2
Begum, M.3
-
49
-
-
79955921754
-
Folfirinox versus gemcitabine for metastatic pancreatic cancer
-
Conroy T, Desseigne F, Ychou M et al. FOLFIRINOX versus gemcitabine for metastatic pancreatic cancer. N. Engl. J. Med. 364(19), 1817-1825 (2011
-
(2011)
N. Engl. J. Med
, vol.364
, Issue.19
, pp. 1817-1825
-
-
Conroy, T.1
Desseigne, F.2
Ychou, M.3
-
50
-
-
84865080615
-
The pancreas cancer microenvironment
-
Feig C, Gopinathan A, Neesse A, Chan DS, Cook N, Tuveson DA. The pancreas cancer microenvironment. Clin. Cancer Res. 18(16), 4266-4276 (2012
-
(2012)
Clin. Cancer Res
, vol.18
, Issue.16
, pp. 4266-4276
-
-
Feig, C.1
Gopinathan, A.2
Neesse, A.3
Chan, D.S.4
Cook, N.5
Tuveson, D.A.6
-
51
-
-
84860112131
-
What we have learned about pancreatic cancer from mouse models
-
Perez-Mancera PA, Guerra C, Barbacid M, Tuveson DA. What we have learned about pancreatic cancer from mouse models. Gastroenterology 142(5), 1079-1092 (2012
-
(2012)
Gastroenterology
, vol.142
, Issue.5
, pp. 1079-1092
-
-
Perez-Mancera, P.A.1
Guerra, C.2
Barbacid, M.3
Tuveson, D.A.4
-
52
-
-
6044267987
-
The absence of human equilibrative nucleoside transporter 1 is associated with reduced survival in patients with gemcitabine-Treated pancreas adenocarcinoma
-
Spratlin J, Sangha R, Glubrecht D et al. The absence of human equilibrative nucleoside transporter 1 is associated with reduced survival in patients with gemcitabine-Treated pancreas adenocarcinoma. Clin. Cancer Res. 10(20), 6956-6961 (2004
-
(2004)
Clin. Cancer Res
, vol.10
, Issue.20
, pp. 6956-6961
-
-
Spratlin, J.1
Sangha, R.2
Glubrecht, D.3
-
53
-
-
59849115856
-
Human equilibrative nucleoside transporter 1 levels predict response to gemcitabine in patients with pancreatic cancer
-
Farrell JJ, Elsaleh H, Garcia M et al. Human equilibrative nucleoside transporter 1 levels predict response to gemcitabine in patients with pancreatic cancer. Gastroenterology 136(1), 187-195 (2009
-
(2009)
Gastroenterology
, vol.136
, Issue.1
, pp. 187-195
-
-
Farrell, J.J.1
Elsaleh, H.2
Garcia, M.3
-
54
-
-
84865021068
-
Immunohistochemical analysis of human equilibrative nucleoside transporter-1 (hENT1) predicts survival in resected pancreatic cancer patients treated with adjuvant gemcitabine monotherapy
-
Morinaga S, Nakamura Y, Watanabe T et al. Immunohistochemical analysis of human equilibrative nucleoside transporter-1 (hENT1) predicts survival in resected pancreatic cancer patients treated with adjuvant gemcitabine monotherapy. Ann. Surg. Oncol. 19(Suppl. 3), S558-S564 (2012
-
(2012)
Ann. Surg. Oncol
, vol.19
, Issue.SUPPL. 3
-
-
Morinaga, S.1
Nakamura, Y.2
Watanabe, T.3
-
55
-
-
84867404707
-
Human equilibrative nucleoside transporter 1 expression is a strong independent prognostic factor in UICC T3-T4 pancreatic cancer patients treated with preoperative gemcitabine-based chemoradiotherapy
-
Murata Y, Hamada T, Kishiwada M et al. Human equilibrative nucleoside transporter 1 expression is a strong independent prognostic factor in UICC T3-T4 pancreatic cancer patients treated with preoperative gemcitabine-based chemoradiotherapy. J. Hepatobiliary Pancreat. Sci. 19(4), 413-425 (2012
-
(2012)
J. Hepatobiliary Pancreat. Sci
, vol.19
, Issue.4
, pp. 413-425
-
-
Murata, Y.1
Hamada, T.2
Kishiwada, M.3
-
56
-
-
84865017503
-
Combined analysis of dihydropyrimidine dehydrogenase and human equilibrative nucleoside transporter 1 expression predicts survival of pancreatic carcinoma patients treated with adjuvant gemcitabine plus S 1 chemotherapy after surgical resection
-
Kondo N, Murakami Y, Uemura K et al. Combined analysis of dihydropyrimidine dehydrogenase and human equilibrative nucleoside transporter 1 expression predicts survival of pancreatic carcinoma patients treated with adjuvant gemcitabine plus S 1 chemotherapy after surgical resection. Ann. Surg. Oncol. 19(Suppl. 3), S646-S655 (2012
-
(2012)
Ann. Surg. Oncol
, vol.19
, Issue.SUPPL. 3
-
-
Kondo, N.1
Murakami, Y.2
Uemura, K.3
-
57
-
-
84858733250
-
Is there a role for the quantification of RRM1 and ERCC1 expression in pancreatic ductal adenocarcinoma?
-
Valsecchi ME, Holdbrook T, Leiby BE et al. Is there a role for the quantification of RRM1 and ERCC1 expression in pancreatic ductal adenocarcinoma? BMC Cancer 12, 104 (2012
-
(2012)
BMC Cancer
, vol.12
, pp. 104
-
-
Valsecchi, M.E.1
Holdbrook, T.2
Leiby, B.E.3
-
58
-
-
33645731188
-
Transcription analysis of human equilibrative nucleoside transporter-1 predicts survival in pancreas cancer patients treated with gemcitabine
-
Giovannetti E, Del Tacca M, Mey V et al. Transcription analysis of human equilibrative nucleoside transporter-1 predicts survival in pancreas cancer patients treated with gemcitabine. Cancer Res. 66(7), 3928-3935 (2006
-
(2006)
Cancer Res
, vol.66
, Issue.7
, pp. 3928-3935
-
-
Giovannetti, E.1
Del Tacca, M.2
Mey, V.3
-
59
-
-
79960023038
-
Prognostic roles of human equilibrative transporter 1 (hENT-1) and ribonucleoside reductase subunit M1 (RRM1) in resected pancreatic cancer
-
Kim R, Tan A, Lai KK et al. Prognostic roles of human equilibrative transporter 1 (hENT-1) and ribonucleoside reductase subunit M1 (RRM1) in resected pancreatic cancer. Cancer 117(14), 3126-3134 (2011
-
(2011)
Cancer
, vol.117
, Issue.14
, pp. 3126-3134
-
-
Kim, R.1
Tan, A.2
Lai, K.K.3
-
60
-
-
84872076683
-
An analysis of human equilibrative nucleoside transporter-1, ribonucleoside reductase subunit M1, ribonucleoside reductase subunit M2, and excision repair cross-complementing gene-1 expression in patients with resected pancreas adenocarcinoma: Implications for adjuvant treatment
-
Fisher SB, Patel SH, Bagci P et al. An analysis of human equilibrative nucleoside transporter-1, ribonucleoside reductase subunit M1, ribonucleoside reductase subunit M2, and excision repair cross-complementing gene-1 expression in patients with resected pancreas adenocarcinoma: Implications for adjuvant treatment. Cancer 119(2), 445-453 (2013
-
(2013)
Cancer
, vol.119
, Issue.2
, pp. 445-453
-
-
Fisher, S.B.1
Patel, S.H.2
Bagci, P.3
|