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Volumn 26, Issue 1, 2013, Pages 179-188

Knockdown of Axl receptor tyrosine kinase in osteosarcoma cells leads to decreased proliferation and increased apoptosis

Author keywords

AKT; Apoptosis; Axl receptor tyrosine kinase; Clinicopathology; Proliferation

Indexed keywords

AXL RECEPTOR TYROSINE KINASE; KI 67 ANTIGEN; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN KINASE B; TYROSINE KINASE RECEPTOR; UNCLASSIFIED DRUG; PROTEIN TYROSINE KINASE; SHORT HAIRPIN RNA;

EID: 84881257216     PISSN: 03946320     EISSN: None     Source Type: Journal    
DOI: 10.1177/039463201302600117     Document Type: Article
Times cited : (26)

References (25)
  • 2
    • 79960316237 scopus 로고    scopus 로고
    • Relationships between levels of CXCR4 and VEGF and blood-borne metastasis and survival in patients with osteosarcoma
    • Lin F, Zheng SE, Shen Z, Tang LN, Chen P, Sun YJ, Zhao H, Yao Y. Relationships between levels of CXCR4 and VEGF and blood-borne metastasis and survival in patients with osteosarcoma. Med Oncol 2011; 28:649-53.
    • (2011) Med Oncol , vol.28 , pp. 649-653
    • Lin, F.1    Zheng, S.E.2    Shen, Z.3    Tang, L.N.4    Chen, P.5    Sun, Y.J.6    Zhao, H.7    Yao, Y.8
  • 3
    • 77952062040 scopus 로고    scopus 로고
    • APEX1 gene amplification and Its Protein overexpression in osteosarcoma: Correlation with recurrence, metastasis, and survival
    • Yang JL, Yang D, Cogdell D, et al. APEX1 gene amplification and Its Protein overexpression in osteosarcoma: correlation with recurrence, metastasis, and survival. Technol Cancer Res Treat 2010; 9:161-69.
    • (2010) Technol Cancer Res Treat , vol.9 , pp. 161-169
    • Yang, J.L.1    Yang, D.2    Cogdell, D.3
  • 4
    • 33751292686 scopus 로고    scopus 로고
    • Gastric and intestinal phenotypic marker expression in early differentiated-type tumors of the stomach: Clinicopathologic significance and genetic background
    • DOI 10.1158/1078-0432.CCR-06-1339
    • Tajima Y, Yamazaki K, Makino R, et al. Gastric and intestinal phenotypic marker expression in early differentiated-type tumors of the stomach: clinicopathologic significance and genetic background. Clin Cancer Res 2006; 12:6469-79. (Pubitemid 44799720)
    • (2006) Clinical Cancer Research , vol.12 , Issue.21 , pp. 6469-6479
    • Tajima, Y.1    Yamazaki, K.2    Makino, R.3    Nishino, N.4    Aoki, S.5    Kato, M.6    Morohara, K.7    Kaetsu, T.8    Kusano, M.9
  • 5
    • 84857065479 scopus 로고    scopus 로고
    • Axl-dependent signaling: A clinical update
    • Korshunov VA. Axl-dependent signaling: a clinical update. Clin Sci (Lond) 2012; 122:361-8.
    • (2012) Clin Sci (Lond) , vol.122 , pp. 361-368
    • Korshunov, V.A.1
  • 7
    • 0344464864 scopus 로고    scopus 로고
    • Clinical implications of coexpression of growth arrest-specific gene 6 and receptor tyrosine kinases Axl and sky in human uterine leiomyoma
    • DOI 10.1093/molehr/gag082
    • Sun WS, Fujimoto J, Tamaya T. Clinical implications of coexpression of growth arrest-specific gene 6 and receptor tyrosine kinases Axl and Sky in human uterine leiomyoma. Mol Hum Reprod 2003; 9:701-7. (Pubitemid 37483957)
    • (2003) Molecular Human Reproduction , vol.9 , Issue.11 , pp. 701-707
    • Sun, W.S.1    Fujimoto, J.2    Tamaya, T.3
  • 9
    • 5644239572 scopus 로고    scopus 로고
    • Coexpression of Gas6/Axl in human ovarian cancers
    • DOI 10.1159/000079499
    • Sun W, Fujimoto J, Tamaya T. Coexpression of Gas6/Axl in human ovarian cancers. Oncology 2004; 66:450-7. (Pubitemid 39370236)
    • (2004) Oncology , vol.66 , Issue.6 , pp. 450-457
    • Sun, W.1    Fujimoto, J.2    Tamaya, T.3
  • 10
    • 70349705633 scopus 로고    scopus 로고
    • Axl as a potential therapeutic target in cancer: Role of Axl in tumor growth, metastasis and angiogenesis
    • Li Y, Ye X, Tan C, et al. Axl as a potential therapeutic target in cancer: role of Axl in tumor growth, metastasis and angiogenesis. Oncogene 2009; 28:3442-55.
    • (2009) Oncogene , vol.28 , pp. 3442-3455
    • Li, Y.1    Ye, X.2    Tan, C.3
  • 12
    • 0034783451 scopus 로고    scopus 로고
    • Axl receptor tyrosine kinase expression in human lung cancer cell lines correlates with cellular adhesion
    • DOI 10.1016/S0959-8049(01)00271-4, PII S0959804901002714
    • Wimmel A, Glitz D, Kraus A, Roeder J, Schuermann M. Axl receptor tyrosine kinase expression in human lung cancer cell lines correlates with cellular adhesion. Eur J Cancer 2001; 37:2264-74. (Pubitemid 33001299)
    • (2001) European Journal of Cancer , vol.37 , Issue.17 , pp. 2264-2274
    • Wimmel, A.1    Glitz, D.2    Kraus, A.3    Roeder, J.4    Schuermann, M.5
  • 17
    • 33645821049 scopus 로고    scopus 로고
    • Dominant-negative inhibition of the Axl receptor tyrosine kinase suppresses brain tumor cell growth and invasion and prolongs survival
    • Vajkoczy P, Knyazev P, Kunkel A, et al. Dominant-negative inhibition of the Axl receptor tyrosine kinase suppresses brain tumor cell growth and invasion and prolongs survival. Proc Natl Acad Sci USA 2006; 103:5799-804.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 5799-5804
    • Vajkoczy, P.1    Knyazev, P.2    Kunkel, A.3
  • 18
    • 77957109253 scopus 로고    scopus 로고
    • An anti-Axl monoclonal antibody attenuates xenograft tumor growth and enhances the effect of multiple anticancer therapies
    • Ye X, Li Y, Stawicki S, Couto S, et al. An anti-Axl monoclonal antibody attenuates xenograft tumor growth and enhances the effect of multiple anticancer therapies. Oncogene 2010; 29:5254-64.
    • (2010) Oncogene , vol.29 , pp. 5254-5264
    • Ye, X.1    Li, Y.2    Stawicki, S.3    Couto, S.4
  • 19
    • 77957375963 scopus 로고    scopus 로고
    • AXL is an essential factor and therapeutic target for metastatic ovarian cancer
    • Rankin EB, Fuh KC, Taylor TE, et al. AXL is an essential factor and therapeutic target for metastatic ovarian cancer. Cancer Res 2010; 70:7570-9.
    • (2010) Cancer Res , vol.70 , pp. 7570-7579
    • Rankin, E.B.1    Fuh, K.C.2    Taylor, T.E.3
  • 20
    • 14944381154 scopus 로고    scopus 로고
    • PI3K/AKT is involved in mediating survival signals that rescue Ewing tumour cells from fibroblast growth factor 2-induced cell death
    • DOI 10.1038/sj.bjc.6602384
    • Hotfilder M, Sondermann P, Senss A, van Valen F, Jürgens H, Vormoor J. PI3K/AKT is involved in mediating survival signals that rescue Ewing tumor cells from fibroblast growth factor 2-induced cell death. Br J Cancer 2005; 92:705-10. (Pubitemid 40460607)
    • (2005) British Journal of Cancer , vol.92 , Issue.4 , pp. 705-710
    • Hotfilder, M.1    Sondermann, P.2    Senss, A.3    Van Valen, F.4    Jurgens, H.5    Vormoor, J.6
  • 21
    • 79952071312 scopus 로고    scopus 로고
    • Blockade of the Ras/MEK/ERK and Ras/PI3K/Akt pathways by statins reduces the expression of bFGF, HGF, and TGF-β as angiogenic factors in mouse osteosarcoma
    • Tsubaki M, Yamazoe Y, Yanae M, et al. Blockade of the Ras/MEK/ERK and Ras/PI3K/Akt pathways by statins reduces the expression of bFGF, HGF, and TGF-β as angiogenic factors in mouse osteosarcoma. Cytokine 2011; 54:100-107.
    • (2011) Cytokine , vol.54 , pp. 100-107
    • Tsubaki, M.1    Yamazoe, Y.2    Yanae, M.3
  • 22
    • 33847008999 scopus 로고    scopus 로고
    • Growth arrest-specific gene 6 and Axl signaling enhances gastric cancer cell survival via Akt pathway
    • Sawabu T, Seno H, Kawashima T, et al. Growth arrest-specific gene 6 and Axl signaling enhances gastric cancer cell survival via Akt pathway. Mol Carcinog 2007; 46:155-64.
    • (2007) Mol Carcinog , vol.46 , pp. 155-164
    • Sawabu, T.1    Seno, H.2    Kawashima, T.3
  • 24
    • 84868118383 scopus 로고    scopus 로고
    • PARP-1 Modulation of mTOR Signaling in Response to a DNA Alkylating Agent
    • Ethier C, Tardif M, Arul L, Poirier GG. PARP-1 Modulation of mTOR Signaling in Response to a DNA Alkylating Agent. PLoS One 2012; 7:e47978.
    • (2012) PLoS One , vol.7
    • Ethier, C.1    Tardif, M.2    Arul, L.3    Poirier, G.G.4
  • 25
    • 74049091776 scopus 로고    scopus 로고
    • Expression of p-Akt and COX-2 in gastric adenocarcinomas and adenovirus mediated Akt1 and COX-2 ShRNA suppresses SGC-7901 gastric adenocarcinoma and U251 glioma cell growth in vitro and in vivo
    • Zhang J, Zhang QY, Fu YC, et al. Expression of p-Akt and COX-2 in gastric adenocarcinomas and adenovirus mediated Akt1 and COX-2 ShRNA suppresses SGC-7901 gastric adenocarcinoma and U251 glioma cell growth in vitro and in vivo. Technol Cancer Res Treat 2009; 8:467-78.
    • (2009) Technol Cancer Res Treat , vol.8 , pp. 467-478
    • Zhang, J.1    Zhang, Q.Y.2    Fu, Y.C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.