Expression of receptor-type tyrosine kinase, Axl, and its ligand, gas6, in pediatric thyroid carcinomas around chernobyl

Thyroid

Volumn 12, Issue 11, 2002, Pages 971-975

  Ito, Masahiro ^a   Nakashima, Masahiro ^b   Nakayama, Toshiyuki ^b   Ohtsuru, Akira ^b   Nagayama, Yuji ^b   Takamura, Noboru ^b   Demedchik, Evgeni P ^c   Sekine, Ichiro ^b   Yamashita, Shunichi ^b  

^a NATIONAL HOSPITAL ORGANIZATION NAGASAKI MEDICAL CENTER   (Japan)

^b NAGASAKI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c Thyroid Cancer Center   (Belarus)

Author keywords

[No Author keywords available]

Indexed keywords

GROWTH ARREST SPECIFIC PROTEIN 6; LIGAND; MESSENGER RNA; PROTEIN AXL; PROTEIN S; PROTEIN TYROSINE KINASE; TYROSINE KINASE RECEPTOR; UNCLASSIFIED DRUG;

ADOLESCENT; ARTICLE; CANCER INVASION; CANCER TISSUE; CARCINOGENESIS; CELL DIFFERENTIATION; CELL GROWTH; CHILDHOOD CANCER; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE ASSOCIATION; ENZYME ACTIVATION; FEMALE; GENE OVEREXPRESSION; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; IONIZING RADIATION; MALE; MALIGNANT TRANSFORMATION; MITOGENESIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FAMILY; SCHOOL CHILD; SIGNAL TRANSDUCTION; THYROID CARCINOMA; THYROID CELL; THYROID PAPILLARY CARCINOMA;

EID: 0036854401     PISSN: 10507256     EISSN: None     Source Type: Journal    
DOI: 10.1089/105072502320908303     Document Type: Article

References (28)

1. Hunter T 1991 Cooperation between Oncogenes. Cell 64:249-270.
2. Schlessinger J, Ullrich A 1992 Growth factor signaling by receptor tyrosine kinases. Neuron 9:383-391.
3. Ullrich A, Schlessinger J 1990 Signal transduction by receptors with tyrosine kinase activity. Cell 61:203-212.
4. Tanaka K, Nagayama Y, Nakano T, Takamura N, Namba H, Fukada S, Kuma K, Yamashita S, Niwa M 1998 Expression profile of receptor-type protein tyrosine kinase genes in the human thyroid. Endocrinology 139:852-858.
5. Klugbauer S, Lengfelder E, Demidchik EP, Rabes HM 1995 High prevalence of RET rearrangement in thyroid tumors of children from Belarus after Chernobyl reactor accident. Oncogene 11:2459-2467.
6. Fugazzola L, Pierotti MA, Vigano E, Pacini F, Vorontsova TV, Bongarzone I 1996 Molecular and biochemical analysis of RET/PTC4, a novel oncogenic rearrangement between RET and ELE1 genes, in a post-Chernobyl papillary thyroid cancer. Oncogene 13:1093-1097.
7. Klugbauer S, Jauch A, Lengfelder E, Demidchik EP, Rabes HM 2000 A novel type of RET rearrangement (PTC8) in childhood papillary thyroid carcinomas and characterization of the involved gene (RFG8). Cancer Res 60:7028-7032.
8. Yasuda Y, Sakanoue Y, Hatada T, Nakai T, Utsunomiya J 1992 Protein tyrosine kinase activity in human thyroid papillary carcinoma. Acta Oncologica 31:409-412.
9. Fagin JA 1994 Molecular genetics of human thyroid neoplasms. Annu Rev Med 45:45-52.
10. Eggo MC, Sheppard MC 1994 Autocrine growth factors produced in the thyroid. Mol Cell Endocrinol. 100:97-102.
11. Challier C, Uphoff CC, Janssen JWG, Drexler HG 1996 Differential expression of the ufo/axl oncogene in human leukemia-lymphoma cell lines. Leukemia 10:781-787.
12. Ito T, Ito M, Shiozawa J, Naito S, Ohtsuru A, Nagayama, Kanematsu T, Yamashita S, Sekine I 1999 Expression of the Axl receptor tyrosine kinase in human thyroid carcinoma. Thyroid 9:563-567.
13. O'Bryan JP, Frye RA, Cogswell PC, Neubauer A, Kitch B, Prokop C, Espinosa III R, Le Beau MM, Earp HS, Liu ET 1991 Axl, a transforming gene isolated from primary human myeloid leukemia cells, encodes a novel receptor tyrosine kinase. Mol Cell Biol 11:5016-5031.
14. Liu E, Hjelle B, Bishop JM 1988 Transforming genes in chronic myelogenous leukemia. Proc Chem 85:1952-1956.
15. Nagata K, Ohashi K, Nakano T, Arita H, Zong C, Hanafusa H, Mizuno K 1996 Identification of the product of growth arrest-specific Gene 6 as a common ligand for Axl, Sky, and Mer receptor tyrosine kinases. J Biol Chem 271:30022-30027.
16. Craven RJ, Xu L, Weiner TM, Fridell YW, Dent GA, Srivastava S, Varnum B, Liu ET, Cance WG 1995 Receptor tyrosine kinasses expressed in metastatic colon cancer. Int J Cancer 60:791-797.
17. Varnum BC, Young C, Elliot G, Garcia A, Bartiey TD, Fridell YW, Hunt RW, Trail G, Clogston C, Toso RJ, Yanagihara D, Bennett L, Sylber M, Merewether L, Tseng A, Escobar E, Liu ET, Yamane HK 1995 Axl receptor tyrosine kinase stimulated by the vitamin K-dependent protein encoded by growth arrest-specific gene6. Nature 373:623-626.
18. Manfioletti G, Brancolini C, Avanzi G, Schneider C 1993 The protein encoded by a growth arrest-specific gene (gas6) Isia new member of the vitamin K-dependent proteins related to protein S, a negative coregulator in the blood coagulation cascade. Mol Cell Biol 13:4976-4985.
19. Li RH, Che J, Hammonds G, Phillips H, Armanini M, Wood P, Bunge R, Godowski PJ, Sliwkowski MX, Mather JP 1996 Identification of Gas6 as a growth factor for human schwann cells. J Neurosci 16:2012-2019.
20. Nakano T, Kawamoto K, Higashino K, Arita H 1996 Prevention of growth arrest-induced cell death of vascular smooth muscle cells by a product of growth arrest-specific gene, gas6. FEBS Lett 387:78-80.
21. Bellosta P, Zhang Q, Goff SP, Basilico C 1997 Signaling through the ARK tyrosine kinase receptor protects from apoptosis in the absence of growth stimulation. Oncogene 15:2387-2397.
22. Basolo F, Pollina L, Fontanini G, Fiore L, Pacini F, Baldanzi A 1997 Apoptosis and proliferation in thyroid carcinoma: Correlation with bcl-2 and p53 protein expression. Br J Cancer 75:537-541.
23. Moore D, Ohene-Fianko D, Garcia B, Chakrabarti S 1998 Apoptosis in thyroid neoplasms: Relationship with p53 and bcl-2 expression. Histopathology 32:35-42.
24. Ashizawa K, Shibata Y, Yamashita S, Namba H, Hoshi M, Yokoyama N, Nagataki S 1997 Prevalence of goiter and urinary iodine excretion levels in children around Chernobyl J Clin Endocrinol Metab 82:3430-3433.
25. Shirahige Y, Ito M, Ashizawa K, Motomura T, Yokoyama N, Namba H, Fukata S, Yokozawa T, Ishikawa N, Mimura T, Yamashita S, Sekine I, Kuma K, Ito K, Nagataki S 1998 Childhood thyroid cancer: Comparison of Japan and Belarus. Endocr J 45:203-209.
26. Wajjwalku W, Nakamura S, Hasegawa Y, Miyazaki K, Satoh Y, Funahashi H, Matsuyama M, Takahashi M 1992 Low frequency of rearrangement of the ret and trk proto-oncogenes in Japanese thyroid papillary carcinomas. Jpn J Cancer Res 83:671-675.
27. Motomura T, Nikifiriv YE, Namba H, Ashizawa K, Nagataki S, Yamashita S, Fagin JA 1998 Ret rearrangements in Japanese pediatric and adult papillary thyroid cancers. Thyroid 8:485-489.
28. Kitamura Y, Minobe K, Nakata T, Shimizu K, Tanaka S, Fujumori M, Yokoyama S, Ito K, Onda M, Emi M 1999 Ret/PTC3 is the most frequent form of gene rearrangement in papillary thyroid carcinomas in Japan. J Hum Genet 44:96-102.