Microglial ramification and redistribution concomitant with the attenuation of choroidal neovascularization by neuroprotectin D1

Molecular Vision

Volumn 19, Issue , 2013, Pages 1747-1759

  Sheets, Kristopher G ^a   Jun, Bokkyoo ^a   Zhou, Yongdong ^a   Zhu, Min ^b   Petasis, Nicos A ^b   Gordon, William C ^a   Bazan, Nicolas G ^a  

^a LOUISIANA STATE UNIVERSITY HEALTH SCIENCES CENTER   (United States)

^b UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EYE DROPS; FLUORESCEIN; ISOLECTIN B4; NEUROPECTIN D1; TROPICAMIDE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL ACTIVATION; CONTROLLED STUDY; DRUG BIOAVAILABILITY; DRUG EFFECT; DRUG EFFICACY; FACTORIAL ANALYSIS; FLUORESCENCE ANGIOGRAPHY; FRACTAL ANALYSIS; IMAGE ANALYSIS; IMMUNOFLUORESCENCE; LASER; MALE; MICROGLIA; MICROGLIA RAMIFICATION; MOUSE; NEUROPHYSIOLOGICAL RECRUITMENT; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; SUBRETINAL NEOVASCULARIZATION; THREE DIMENSIONAL IMAGING;

ADMINISTRATION, TOPICAL; ANIMALS; CELL SHAPE; CHOROIDAL NEOVASCULARIZATION; DOCOSAHEXAENOIC ACIDS; FLUORESCEIN ANGIOGRAPHY; LASERS; MALE; MASS SPECTROMETRY; MICE; MICE, INBRED C57BL; MICROGLIA;

EID: 84881255806     PISSN: None     EISSN: 10900535     Source Type: Journal    
DOI: None     Document Type: Article

References (30)

1. Caputo M, Zirpoli H, Di Benedetto R, De Nadai K, Tecce MF. Perspectives of choroidal neovascularization therapy. Curr Drug Targets 2011; 12:234-42. [PMID: 20887238].
2. Combadière C, Feumi C, Raoul W, Keller N, Rodéro M, Pézard A, Lavalette S, Houssier M, Jonet L, Picard E, Debré P, Sirinyan M, Deterre P, Ferroukhi T, Cohen SY, Chauvaud D, Jeanny JC, Chemtob S, Behar-Cohen F, Sennlaub F. CX3CR1-dependent subretinal microglia cell accumulation is associated with cardinal features of age-related macular degeneration. J Clin Invest 2007; 117:2920-8. [PMID: 17909628].
3. Streit WJ. Microglia as neuroprotective, immunocompetent cells of the CNS. Glia 2002; 40:133-9. [PMID: 12379901].
4. Buschini E, Piras A, Nuzzi R, Vercelli A. Age related macular degeneration and drusen: neuroinflammation in the retina. Prog Neurobiol 2011; 95:14-25. [PMID: 21740956].
5. Gupta N, Brown KE, Milam AH. Activated microglia in human retinitis pigmentosa, late-onset retinal degeneration, and age-related macular degeneration. Exp Eye Res 2003; 76:463-71. [PMID: 12634111].
6. Sheets KG, Zhou Y, Ertel MK, Knott EJ, Regan CE Jr, Elison JR, Gordon WC, Gjorstrup P, Bazan NG. Neuroprotectin D1 attenuates laser-induced choroidal neovascularization in mouse. Mol Vis 2010; 16:320-9. [PMID: 20216940].
7. Mukherjee PK, Marcheselli VL, Barreiro S, Hu J, Bok D, Bazan NG. Neurotrophins enhance retinal pigment epithelial cell survival through neuroprotectin D1 signaling. Proc Natl Acad Sci USA 2007; 104:13152-7. [PMID: 17670936].
8. Mukherjee PK, Marcheselli VL, de Rivero Vaccari JC, Gordon WC, Jackson FE, Bazan NG. Photoreceptor outer segment phagocytosis attenuates oxidative stress-induced apoptosis with concomitant neuroprotectin D1 synthesis. Proc Natl Acad Sci USA 2007; 104:13158-63. [PMID: 17670935].
9. Marcheselli VL, Hong S, Lukiw WJ, Tian XH, Gronert K, Musto A, Hardy M, Gimenez JM, Chiang N, Serhan CN, Bazan NG. Novel docosanoids inhibit brain ischemia-reperfusion-mediated leukocyte infiltration and pro-inflammatory gene expression. J Biol Chem 2003; 278:43807-17. [PMID: 12923200].
10. Petasis NA, Yang R, Winkler JW, Zhu M, Uddin J, Bazan NG, Serhan CN. Stereocontrolled total synthesis of neuroprotectin D1/protectin D1 and its aspirin-triggered stereoisomer. Tetrahedron Lett 2012; 53:1695-8. [PMID: 22690022].
11. Henden PC, Bache-Wiig J. Fractal Count Plugin. Programvareverkstedet ved Norges Teknisk Naturvitenskapelige Universitet; 2005. Available at: http://www.pvv.org/~perchrh/imagej/fractal.html.
12. Milliken GA, Johnson DE. Analysis of Messy Data Volume 1: Designed Experiments, Second Edition. 2nd ed. Boca Raton, FL: Chapman and Hall/CRC; 2004.
13. Goerg GM. The Lambert Way to Gaussianize skewed, heavy tailed data with the inverse of Tukey's h transformation as a special case. arXiv. 2010;1010.2265(4):1-40. Available at: http://arxiv.org/abs/1010.2265. Accessed November 11, 2011.
14. Goerg GM, Lambert W. Random Variables-A New Family of Generalized Skewed Distributions with Applications to Risk Estimation. Annals of Applied Statistics 2011; 5:2197-230.
15. Long JS, Ervin LH. Using heteroscedasticity consistent standard errors in the linear regression model. Am Stat 2000; 54:217-24.
16. Edelhauser HF, Rowe-Rendleman CL, Robinson MR, Dawson DG, Chader GJ, Grossniklaus HE, Rittenhouse KD, Wilson CG, Weber DA, Kuppermann BD, Csaky KG, Olsen TW, Kompella UB, Holers VM, Hageman GS, Gilger BC, Campochiaro PA, Whitcup SM, Wong WT. Ophthalmic drug delivery systems for the treatment of retinal diseases: basic research to clinical applications. Invest Ophthalmol Vis Sci 2010; 51:5403-20. [PMID: 20980702].
17. Nimmerjahn A, Kirchhoff F, Helmchen F. Resting microglial cells are highly dynamic surveillants of brain parenchyma in vivo. Science 2005; 308:1314-8. [PMID: 15831717].
18. Stence N, Waite M, Dailey ME. Dynamics of microglial activation: a confocal time-lapse analysis in hippocampal slices. Glia 2001; 33:256-66. [PMID: 11241743].
19. Liang KJ, Lee JE, Wang YD, Ma W, Fontainhas AM, Fariss RN, Wong WT. Regulation of dynamic behavior of retinal microglia by CX3CR1 signaling. Invest Ophthalmol Vis Sci 2009; 50:4444-51. [PMID: 19443728].
20. Santos AM, Martín-Oliva D, Ferrer-Martín RM, Tassi M, Calvente R, Sierra A, Carrasco MC, Marín-Teva JL, Navascués J, Cuadros MA. Microglial response to light-induced photoreceptor degeneration in the mouse retina. J Comp Neurol 2010; 518:477-92. [PMID: 20020538].
21. Lee JE, Liang KJ, Fariss RN, Wong WT. Ex vivo dynamic imaging of retinal microglia using time-lapse confocal microscopy. Invest Ophthalmol Vis Sci 2008; 49:4169-76. [PMID: 18487378].
22. Hanisch U-K, Kettenmann H. Microglia: active sensor and versatile effector cells in the normal and pathologic brain. Nat Neurosci 2007; 10:1387-94. [PMID: 17965659].
23. Kettenmann H, Hanisch U-K, Noda M, Verkhratsky A. Physiology of microglia. Physiol Rev 2011; 91:461-553. [PMID: 21527731].
24. Soltys Z, Orzylowska-Sliwinska O, Zaremba M, Orlowski D, Piechota M, Fiedorowicz A, Janeczko K, Oderfeld-Nowak B. Quantitative morphological study of microglial cells in the ischemic rat brain using principal component analysis. J Neurosci Methods 2005; 146:50-60. [PMID: 15935220].
25. Soltys Z, Ziaja M, Pawlínski R, Setkowicz Z, Janeczko K. Morphology of reactive microglia in the injured cerebral cortex. Fractal analysis and complementary quantitative methods. J Neurosci Res 2001; 63:90-7. [PMID: 11169618].
26. Lukiw WJ, Ottlecz A, Lambrou G, Grueninger M, Finley J, Thompson HW, Bazan NG. Coordinate activation of HIF-1 and NF-kappaB DNA binding and COX-2 and VEGF expression in retinal cells by hypoxia. Invest Ophthalmol Vis Sci 2003; 44:4163-70. [PMID: 14507857].
27. Lukiw WJ, Cui J-G, Marcheselli VL, Bodker M, Botkjaer A, Gotlinger K, Serhan CN, Bazan NG. A role for docosahexaenoic acid-derived neuroprotectin D1 in neural cell survival and Alzheimer disease. J Clin Invest 2005; 115:2774-83. [PMID: 16151530].
28. Didier N, Romero IA, Créminon C, Wijkhuisen A, Grassi J, Mabondzo A. Secretion of interleukin-1beta by astrocytes mediates endothelin-1 and tumour necrosis factor-alpha effects on human brain microvascular endothelial cell permeability. J Neurochem 2003; 86:246-54. [PMID: 12807444].
29. Qin Q, Patil KA, Gronert K, Sharma SC. Neuroprotectin D1 inhibits retinal ganglion cell death following axotomy. Prostaglandins Leukot Essent Fatty Acids 2008; 79:201-7. [PMID: 19019647].
30. Roh M, Zhang Y, Murakami Y, Thanos A, Lee SC, Vavvas DG, Benowitz LI, Miller JW. Etanercept, a widely used inhibitor of tumor necrosis factor-α (TNF-α), prevents retinal ganglion cell loss in a rat model of glaucoma. PLoS ONE 2012; 7:e40065-[PMID: 22802951].