Ubiquitin E3 ligase itch negatively regulates osteoclast formation by promoting deubiquitination of tumor necrosis factor (TNF) receptor-associated factor 6

Journal of Biological Chemistry

Volumn 288, Issue 31, 2013, Pages 22359-22368

  Zhang, Hengwei ^a   Wu, Chengwu ^a   Matesic, Lydia E ^b   Li, Xing ^a,c   Wang, Zhiyu ^c   Boyce, Brendan F ^a   Xing, Lianping ^a  

^a UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

^b UNIVERSITY OF SOUTH CAROLINA   (United States)

^c HEBEI MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CYLINDROMATOSIS; DEUBIQUITINATING ENZYMES; E3 LIGASE; OSTEOCLAST FORMATION; OSTEOCLAST PRECURSOR; OSTEOCLASTOGENESIS; TUMOR NECROSIS FACTORS; UBIQUITIN;

BIOCHEMISTRY;

BIOLOGY;

CYLD PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LIPOPOLYSACCHARIDE; OSTEOCLAST DIFFERENTIATION FACTOR; PROTEIN C FOS; TRANSCRIPTION FACTOR NFAT; TRANSCRIPTION FACTOR NFATC1; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 6; UBIQUITIN E3 LIGASE ITCH; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG;

ADULT ANIMAL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BINDING SITE; BONE MARROW CELL; BONE MASS; CONTROLLED STUDY; DEUBIQUITINATION; MALE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; OSTEOCLAST; OSTEOCLASTOGENESIS; OSTEOLYSIS; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN MODIFICATION; SIGNAL TRANSDUCTION; SPLEEN CELL; UPREGULATION;

BONE; DEGRADATION; DEUBIQUITINATION; ITCH; NF-ΚB; OSTEOCLAST; OSTEOCLASTS; TRAF6; UBIQUITINATION;

ANIMALS; BASE SEQUENCE; DNA PRIMERS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NF-KAPPA B; OSTEOCLASTS; POLYMERASE CHAIN REACTION; RANK LIGAND; SIGNAL TRANSDUCTION; TNF RECEPTOR-ASSOCIATED FACTOR 6; UBIQUITIN-PROTEIN LIGASES; UBIQUITINATION;

EID: 84881248940     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.442459     Document Type: Article

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