Estimation of absorbed cadmium in tissues of male and female albino rats through different routes of administration

Nigerian Journal of Physiological Sciences

Volumn 26, Issue 1, 2011, Pages 97-101

  Nwokocha, C R ^a   Nwokocha, M I ^a   Owu, D U ^a   Edidjana, E ^b   Nwogbo, N ^b   Ekpo, U ^b   Ufearo, C S ^c  

^a UNIVERSITY OF THE WEST INDIES   (Jamaica)

^b MADONNA UNIVERSITY   (Nigeria)

^c NNAMDI AZIKIWE UNIVERSITY   (Nigeria)

Author keywords

Cadmium; Heavy metals; Organs; Route of administration; Sex

Indexed keywords

CADMIUM CHLORIDE; DRINKING WATER;

ALBINISM; ANIMAL; ARTICLE; BODY BURDEN; COMPARATIVE STUDY; FEMALE; FOOD; GENETICS; INTRAPERITONEAL DRUG ADMINISTRATION; MALE; METABOLISM; ORAL DRUG ADMINISTRATION; RAT; SEX DIFFERENCE; TIME; TISSUE DISTRIBUTION;

ADMINISTRATION, ORAL; ALBINISM; ANIMALS; BODY BURDEN; CADMIUM CHLORIDE; DRINKING WATER; FEMALE; FOOD; INJECTIONS, INTRAPERITONEAL; MALE; RATS; SEX FACTORS; TIME FACTORS; TISSUE DISTRIBUTION;

EID: 84881244296     PISSN: 0794859X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (30)

1. Agency for Toxic Substance and Disease Registry (ATSDR) 2003: Toxicological Profile for Cadmium. U.S. Department of Health and Humans Services, Public Health Service, Centers for Disease Control; Atlanta, GA.
2. Andersen, M. E., Sarangapani, R., Reitz, R. H., Gallavan, R. H., Dobrev, I. D., and Plotzke, K. P. (2001). Physiological modeling reveals novel pharmacokinetic behavior for inhaled octamethylcyclotetrasiloxane in rats. Toxicol. Sci.; 60: 214-231.
3. Beltrame M.O, De Marco S.G, Marcovecchio J.E. (2009). Influences of sex, habitat, and seasonality on heavy-metal concentrations in the burrowing crab (Neohelice granulata) from a coastal lagoon in Argentina, Arch Environ Contam Toxicol.;58: 746-56.
4. Bhattacharyya, M.H, Wilson, A.K, Tajan, S.S, Jonah M. (2000). Biochemical pathways in cadmium toxicity. In: Zalups RK, Koropatnick J, editors. Molecular Biology and Toxicology of Metals. Taylor and Francis; London. pp. 34-74.
5. Blazka M.E, Shaikh Z.A. (1991a). Differences in cadmium and mercury uptakes by hepatocytes: role of calcium channels. Toxicol. Appl. Pharmacol. 110: 355-363.
6. Blazka M.E, Shaikh Z.A. (1991b). Sex differences in hepatic and renal cadmium accumulation and metallothionein induction. Role of estradiol. Biochem Pharmacol. 41: 775-80.
7. Dawson D.C, Ballatori N. (1995). Membrane transporters as sites of action and routes of entry for toxic metals. In: Goyer RA, Cherian MG, editors. Toxicology of Metals. Springer-Verlag; Berlin. pp. 53-76.
8. Dudley R.E, Gammal L.M, Klaassen C.D. (1985). Cadmium-induced hepatic and renal injury in chronically exposed rats: likely role of hepatic cadmium-metallothionein in nephrotoxicity. Toxicol. Appl. Pharmacol. 77: 414-426.
9. Franklin N.M, Glover C.N, Nicol J.A, Wood C.M. (2005). Calcium/cadmium interactions at uptake surfaces in rainbow trout: waterborne versus dietary routes of exposure. Environ Toxicol Chem; 24: 2954-64.
10. Friberg L, Elinder C.G, Kjellstron T, (1986). General summary and conclusions and some aspects of diagnosis and treatment of chronic cadmium poisoning. In: Friberg L, Elinder CG, Kjellstrom T, et al., editors. Cadmium and Health: A Toxicological and Epidemiological Appraisal. Vol. 2. CRC Press; Boca Raton, FL. pp. 247-263.
11. Friedman P.A, Gesek F.A. (1994). Cadmium uptake by kidney distal convoluted tubule cells. Toxicol. Appl. Pharmacol. 128: 257-263.
12. Höfer N, Diel P, Wittsiepe J, Wilhelm M, Degen G.H. (2009). Dose- and route-dependent hormonal activity of the metalloestrogen cadmium in the rat uterus. Toxicol Lett. 191:123-31.
13. Jarup L, Berglund M, Elinder C.G, Nordberg G, Vahter M. (1998). Health effects of cadmium exposure: a review of the literature and a risk estimate. Scand. J. Work Environ Health. 1:1-51.
14. Kasprzak K.S, Poirier L.A. (1985). Effects of calcium and magnesium acetates on tissue distribution of carcinogenic doses of cadmium chloride in Wistar rats. Toxicology. 34: 221-30.
15. Lanszki J, Orosz E, Sugár L. (2009). Metal levels in tissues of Eurasian otters (Lutra lutra) from Hungary: variation with sex, age, condition and location. Chemosphere. 74: 741-3.
16. Leslie E.M, Deeley R.G, Cole S.P. (2001). Toxicological relevance of the multidrug resistance protein 1, MRP1 (ABCC1) and related transporters. Toxicology.;167:3-23.
17. Liu J, Chen H, Miller D.S, Saavedra J.E, Keefer L.K, Johnson D.R, Klaassen C.D, Waalkes M.P. (2001). Overexpression of glutathione S-transferase II and multidrug resistance transport proteins is associated with acquired tolerance to inorganic arsenic. Mol. Pharmacol. 60: 302-309.
18. Liu J, Liu Y, Habeebu SM, Waalkes MP, Klaassen CD. (2000). Chronic combined exposure to cadmium and arsenic exacerbates nephrotoxicity, particularly in metallothionein-I/II null mice. Toxicology. 147: 157-166.
19. Martin M.B, Reiter R, Pham T, Avellanet Y.R, Camara J, Lahm M, Pentecost E, Pratap K, Gilmore B.A, Divekar S, Dagata R.S, Bull J.L, Stoica A. (2003). Estrogen-like activity of metals in Mcf-7 breast cancer cells. Endocrinology. 144: 2425-2436.
20. Massányi P, Tataruch F, Slameka J, Toman R, Jurík R. (2003). Accumulation of cadmium, cadmium, and mercury in liver and kidney of the brown hare (Lepus europaeus) in relation to the season, age, and sex in the West Slovakian Lowland. J Environ Sci Health A Tox Hazard Subst Environ Eng. 38: 1299-309.
21. Miranda M, Alonso M.L, Castillo C, Hernández J, Benedito J.L. (2000). Effect of sex on arsenic, cadmium, cadmium, copper and zinc accumulation in calves. Vet Hum Toxicol. 42: 265-8.
22. Nwokocha CR, Ufearo CS, Owu DU, Idemudo NC and Ojukwu LC. (2011). In vivo distribution of lead in male and female rats after intraperitoneal and oral administration. Toxicology and Industrial Health. 000(00) 1-6. DOI: 10.1177/0748233711407955.
23. Oberdorster G. (1992). Pulmonary deposition, clearance and effects of inhaled soluble and insoluble cadmium compounds. IARC Sci. Publ. 118: 189-204.
24. Oishi S, Nakagawa J, Ando M. (2000). Effects of cadmium administration on the endogenous metal balance in rats. Biol Trace Elem Res. 76: 257-278.
25. Rautio A, Kunnasranta M, Valtonen A, Ikonen M, Hyvärinen H, Holopainen I.J, Kukkonen J.V., (2010). Sex, Age, and Tissue Specific Accumulation of Eight Metals, Arsenic, and Selenium in the European Hedgehog (Erinaceus europaeus). Arch Environ Contam Toxicol. 59: 642-51
26. Sato M, Takizawa Y, (1982). Cadmium-binding proteins in human organs. Toxicol Lett 11: 269-73.
27. Shimada H, Bare R.M, Hochadel J.F, Waalkes M.P, (1997). Testosterone pretreatment mitigates cadmium toxicity in male C57 mice but not in C3H mice. Toxicology, 116: 183-91.
28. Stoica A, Katzenellenbogen B.S, Martin M.B. (2000). Activation of estrogen receptor-α by the heavy metal cadmium. Mol. Endocrinol. 14: 545-553.
29. Zalups R.K, Ahmad S. (2003). Molecular handling of cadmium in transporting epithelia. Toxicol. Appl. Pharmacol. 186: 163-188.
30. Zalups RK. (2000). Evidence for basolateral uptake of cadmium in the kidneys of rats. Toxicol. Appl. Pharmacol. 164: 15-23.