Effect of rhBMP-2 and osteogenic revulsants on proliferation and differentiation of bone marrow stromal cells in rats

Journal of Huazhong University of Science and Technology - Medical Science

Volumn 27, Issue 5, 2007, Pages 561-563

  Fang, Huang ^a   Yang, Xiaorong ^a   Chen, Anmin ^a   Luo, Yongxiang ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

BMSCs; Osteogenic differentiation; Proliferation; rhBMP 2

Indexed keywords

BONE MORPHOGENETIC PROTEIN; DEXAMETHASONE; RECOMBINANT BONE MORPHOGENETIC PROTEIN 2; RECOMBINANT HUMAN BONE MORPHOGENETIC PROTEIN-2; RECOMBINANT PROTEIN; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL; ARTICLE; BONE DEVELOPMENT; BONE MARROW CELL; CELL DIFFERENTIATION; CELL PROLIFERATION; CYTOLOGY; DRUG EFFECT; RAT; SPRAGUE DAWLEY RAT; STROMA CELL;

ANIMALS; BONE MARROW CELLS; BONE MORPHOGENETIC PROTEINS; CELL DIFFERENTIATION; CELL PROLIFERATION; DEXAMETHASONE; OSTEOGENESIS; RATS; RATS, SPRAGUE-DAWLEY; RECOMBINANT PROTEINS; STROMAL CELLS; TRANSFORMING GROWTH FACTOR BETA;

EID: 36849039990     PISSN: 16720733     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11596-007-0522-2     Document Type: Article

References (10)

1. Prockop D J. Marrow stromal cells as stem cells for nonhematopoietic tissues. Science, 1997,276:71-74
2. David C C, Reiner C, Carla M et al. Rapid expansion of recycling stem cells in cultures of plastic-adherent cells from human bone marrow. Proc Natl Acad Sci U S A, 2000,97(7):3213-3218
3. Noel D, Gazit D, Bouquet C et al. Short-term BMP-2 expression is sufficient for in vivo osteochondral differentiation of mesenchymal stem cells. Stem Cells, 2004,22(1):74-85
4. Lane J M, Yasko A W, Tomin E et al. Bone marrow and recombinant human bone morphogenetic protein-2 in osseous repair. Clin Orthop, 1999,361(4):216-227
5. Troen B R. Molecular mechanisms underlying osteoblast formation and activation. Exp Gerontol, 2003,38: 605-614
6. Chen D. Differential roles for bone morphogenetic protein (BMP) receptor type IB and IA in differentiation and specification of mesenchymal precursor cells to osteoblast and adipocyte lineages. J Cell Biol, 1998,13:295
7. Gronthos S, Zannettin A C, Hay S J et al. Molecular and cellular characterization of highly purified stromal stem cells derived from human bone marrow. J Cell Sci, 2003,116:1827-1835
8. Kim H, Lee J H, Suh H. Interaction of mesenchymal stem cells and in vitro osteogenesis. Yonsei Med J, 2003,44(2):187-197
9. Qian Q C, Liu Y P, Yang W D et al. The biological effects of recombinant human bone morphogenetic protein-2 and basic fibroblast growth factor on human bone marrow stromal cells. J Stomatology (Chinese), 2004,18(4):380-381
10. Lecanda F, Avioli L V, Cheng S L. Regulation of bone matrix protein expression and induction of differentiation of human osteoblasts and human bone marrow stromal cells by bone morphogenetic protein-2. Cell Biochem, 1997,67:389-396