Translating Translational Research into Global Health Gains

PLoS Medicine

Volumn 10, Issue 7, 2013, Pages

  Barbour, Virginia ^a   Clark, Jocalyn ^a   Connell, Laureen ^a   MacDonald, Rhona ^a   Norton, Melissa ^a   Ross, Amy ^a   Simpson, Paul ^a   Winker, Margaret ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC SENSITIVITY; ARTICLE; CANCER PROGNOSIS; CANCER STAGING; CLINICAL PRACTICE; COST BENEFIT ANALYSIS; FUNDING; GENE SEQUENCE; GENOMICS; HEALTH; HUMAN; INCOME; MICROARRAY ANALYSIS; POLYMERASE CHAIN REACTION; PRACTICE GUIDELINE; SENSITIVITY AND SPECIFICITY; SEPSIS; SYSTEMATIC REVIEW (TOPIC); TRANSLATIONAL RESEARCH; TUBERCULOSIS; TUMOR SUPPRESSOR GENE;

EID: 84881231771     PISSN: 15491277     EISSN: 15491676     Source Type: Journal    
DOI: 10.1371/journal.pmed.1001493     Document Type: Article

References (16)

1. Liptak A (June 13, 2013) Justices, 9-0, bar patenting human genes. New York Times online. Available: http://www.nytimes.com/2013/06/14/us/supreme-court-rules-human-genes-may-not-be-patented.html?hpw. Accessed 09 July 13.
2. Supreme Court of the United States (2013) Syllabus: Association for Molecular Pathologyet al. v. Myriad Genetics, Inc.,et al. Certiorari to the United States Court of Appeals for the Federal Circuit. No. 12-398. Available: http://www.supremecourt.gov/opinions/12pdf/12-398_1b7d.pdf. Accessed 09 July 13.
3. Munro D (June 16, 2013) Supreme Court breaks Myriad monopoly. Forbes online. Available: http://www.forbes.com/sites/danmunro/2013/06/16/supreme-court-breaks-myriad-monopoly/. Accessed 09 July 13.
4. Marisa L, de Reyniès A, Duval A, Selves J, Gaub MP, et al. (2013) Gene Expression Classification of Colon Cancer into Molecular Subtypes: Characterization, Validation, and Prognostic Value. PLoS Med 10 (5):: e1001453 doi:10.1371/journal.pmed.1001453.
5. Buchan BW, Ginocchio CC, Manii R, Cavagnolo R, Pancholi P, et al. (2013) Multiplex Identification of Gram-Positive Bacteria and Resistance Determinants Directly from Positive Blood Culture Broths: Evaluation of an Automated Microarray-Based Nucleic Acid Test. PLoS Med 10 (7):: e1001478 doi:10.1371/journal.pmed.1001478.
6. Perks B, (2011) UK plans 30% funding bump for translational research. Nat Med 17: 394 doi:10.1038/nm0411-394b.
7. National Center for Advancing Translational Sciences. Homepage. Available: http://www.ncats.nih.gov/about/about.html. Accessed 09 July 13.
8. Hooijmans CR, Ritskes-Hoitinga M, (2013) Progress in Using Systematic Reviews of Animal Studies to Improve Translational Research. PLoS Med 10 (7):: e1001482 doi:10.1371/journal.pmed.1001482.
9. Kilkenny C, Browne WJ, Cuthill IC, Emerson M, Altman DG, (2010) Improving Bioscience Research Reporting: The ARRIVE Guidelines for Reporting Animal Research. J Pharmacol Pharmacother 1: 94-99 doi: 10.4103/0976-500X.72351.
10. Henderson VC, Kimmelman J, Fergusson D, Grimshaw JM, Hackam DG, (2013) Threats to Validity in the Design and Conduct of Preclinical Efficacy Studies: A Systematic Review of Guidelines for In Vivo Animal Experiments. PLoS Med 10 (7):: e1001489 doi:10.1371/journal.pmed.1001489.
11. WHO (2002) Genomics and World Health. Report of the Advisory Committee on Health Research. Available: http://whqlibdoc.who.int/hq/2002/a74580.pdf. Accessed 09 July 13.
12. Raja S, Ching J, Xi L, Hughes SJ, Chang R, et al. (2005) Technology for automated, rapid, and quantitative PCR or reverse transcription-PCR clinical testing. Clin Chem 51: 882-890.
13. Helb D, Jones M, Story E, Boehme C, Wallace E, et al. (2010) Rapid Detection of Mycobacterium tuberculosis and Rifampin Resistance by Use of On-Demand, Near-Patient Technology. J Clin Microbiol 48: 229-237 doi:10.1128/JCM.01463-09.
14. Evans CA, (2011) GeneXpert-A Game-Changer for Tuberculosis Control? PLoS Med 8 (7):: e1001064 doi:10.1371/journal.pmed.1001064.
15. Lawn SD, Brooks SV, Kranzer K, Nicol MP, Whitelaw A, et al. (2011) Screening for HIV-Associated Tuberculosis and Rifampicin Resistance before Antiretroviral Therapy Using the Xpert MTB/RIF Assay: A Prospective Study. PLoS Med 8 (7):: e1001067 doi:10.1371/journal.pmed.1001067.
16. Vassall A, van Kampen S, Sohn H, Michael JS, John KR, et al. (2011) Rapid Diagnosis of Tuberculosis with the Xpert MTB/RIF Assay in High Burden Countries: A Cost-Effectiveness Analysis. PLoS Med 8 (11):: e1001120 doi:10.1371/journal.pmed.1001120.