1α,25(OH)2-dihydroxyvitamin D3/VDR protects the skin from UVB-induced tumor formation by interacting with the α-catenin pathway

Journal of Steroid Biochemistry and Molecular Biology

Volumn 136, Issue 1, 2013, Pages 229-232

  Jiang, Yan J ^a   Teichert, Arnaud E ^a   Fong, Frankie ^a   Oda, Yuko ^a   Bikle, Daniel D ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Skin tumor; UVB; Wnt catenin

Indexed keywords

BETA CATENIN; CALCITRIOL; CRE RECOMBINASE; CYCLIN D1; SMALL INTERFERING RNA; T CELL FACTOR PROTEIN; TAMOXIFEN; TRANSCRIPTION FACTOR GLI1; VITAMIN D RECEPTOR;

CARCINOGENESIS; CELL PROLIFERATION; HAIR FOLLICLE; HUMAN CELL CULTURE; KERATINOCYTE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN INTERACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; REVIEW; SIGNAL TRANSDUCTION; SKIN CANCER; SKIN PROTECTION; ULTRAVIOLET B RADIATION;

MUS;

EID: 84881175910     PISSN: 09600760     EISSN: 18791220     Source Type: Journal    
DOI: 10.1016/j.jsbmb.2012.09.024     Document Type: Review

References (27)

1. A. Green, D. Battistutta, Incidence and determinants of skin cancer in a high-risk Australian population, International Journal of Cancer 46 (3) (1990) 356-361.
2. A. Kricker, B.K. Armstrong, D.R. English, Sun exposure and non-melanocytic skin cancer, Cancer Causes and Control 5 (4) (1994) 367-392.
3. R.E. Neale, et al., Basal cell carcinoma on the trunk is associated with excessive sun exposure, Journal of the American Academy of Dermatology 56 (3) (2007) 380-386.
4. L. Tremezaygues, et al., Cutaneous photosynthesis of vitamin D: an evolutionary highly-conserved endocrine system that protects against environmental hazards including UV-radiation and microbial infections, Anticancer Research 26 (4A) (2006) 2743-2748.
5. S. Gandini, et al., Meta-analysis of risk factors for cutaneous melanoma: III family history, actinic damage and phenotypic factors, European Journal of Cancer 41 (14) (2005) 2040-2059.
6. A. Osterlind, G. Engholm, O.M. Jensen, Trends in cutaneous malignant melanoma in Denmark 1943-1982 by anatomic site, APMIS 96 (11) (1988) 953-963.
7. L. Tremezaygues, J. Reichrath, From the bench to emerging new clinical concepts: our present understanding of the importance of the vitamin D endocrine system (VDES) for skin cancer, Dermato-Endocrinology 3 (1) (2011) 11-17.
8. J. Xie, et al., Activating smoothened mutations in sporadic basal-cell carcinoma, Nature 391 (6662) (1998) 90-92.
9. 34 selected cells, Bone Marrow Transplantation 17 (5) (1996) 723-727.
10. M.R. Gailani, et al., The role of the human homologue of Drosophila patched in sporadic basal cell carcinomas, Nature Genetics 14 (1) (1996) 78-81.
11. L. Vuolo, et al., Vitamin D and cancer, Frontiers in Endocrinology (Lausanne) 3 (2012) 58.
12. A.E. Teichert, et al., Overexpression of hedgehog signaling is associated with epidermal tumor formation in vitamin D receptor-null mice, Journal of Investigative Dermatology 131 (11) (2011) 2289-2297.
13. G.M. Zinser, J.P. Sundberg, J. Welsh, Vitamin D(3) receptor ablation sensitizes skin to chemically induced tumorigenesis, Carcinogenesis 23 (12) (2002) 2103-2109.
14. T.I. Ellison, et al., Inactivation of the vitamin D receptor enhances susceptibility of murine skin to UV-induced tumorigenesis, Journal of Investigative Dermatology 128 (10) (2008) 2508-2517.
15. 3 signalling, Nature 355 (6359) (1992) 446-449.
16. A.R. Baker, et al., Cloning and expression of full-length cDNA encoding human vitamin D receptor, Proceedings of the National Academy of Sciences of the United States of America 85 (10) (1988) 3294-3298.
17. K. Miyamoto, et al., Structural organization of the human vitamin D receptor chromosomal gene and its promoter, Molecular Endocrinology 11 (8) (1997) 1165-1179.
18. L.A. Crofts, et al., Multiple promoters direct the tissue-specific expression of novel N-terminal variant human vitamin D receptor gene transcripts, Proceedings of the National Academy of Sciences of the United States of America 95 (18) (1998) 10529-10534.
19. S. Shah, et al., The molecular basis of vitamin D receptor and beta-catenin crossregulation, Molecular Cell 21 (6) (2006) 799-809.
20. T. Grigoryan, et al., Deciphering the function of canonical Wnt signals in development and disease: conditional loss- and gain-of-function mutations of beta-catenin in mice, Genes and Development 22 (17) (2008) 2308-2341.
21. H.G. Palmer, et al., The vitamin D receptor is a Wnt effector that controls hair follicle differentiation and specifies tumor type in adult epidermis, PLoS ONE 3 (1) (2008) e1483.
22. U. Gat, et al., De Novo hair follicle morphogenesis and hair tumors in mice expressing a truncated beta-catenin in skin, Cell 95 (5) (1998) 605-614.
23. E.F. Chan, et al., A common human skin tumour is caused by activating mutations in beta-catenin, Nature Genetics 21 (4) (1999) 410-413.
24. Y.J. Jiang, et al., IL-1alpha accelerates stratum corneum formation and improves permeability barrier homeostasis during murine fetal development, Journal of Dermatological Science 54 (2) (2009) 88-98.
25. J. Huelsken, W. Birchmeier, New aspects of Wnt signaling pathways in higher vertebrates, Current Opinion in Genetics and Development 11 (5) (2001) 547-553.
26. M. Ito, et al., Wnt-dependent de novo hair follicle regeneration in adult mouse skin after wounding, Nature 447 (7142) (2007) 316-320.
27. I. Malanchi, et al., Cutaneous cancer stem cell maintenance is dependent on beta-catenin signalling, Nature 452 (7187) (2008) 650-653.