Analysis of Herpes Simplex Virion Tegument ICP4 Derived from Infected Cells and ICP4-Expressing Cells

PLoS ONE

Volumn 8, Issue 8, 2013, Pages

  Pritchard, Suzanne M ^a   Cunha, Cristina W ^a,b   Nicola, Anthony V ^a  

^a WASHINGTON STATE UNIVERSITY   (United States)

^b AGRICULTURAL RESEARCH SERVICE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ICP4 PROTEIN; PROTEASOME; REGULATOR PROTEIN; STRUCTURAL PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL NUCLEUS; CONTROLLED STUDY; GENE DELETION; GENOTYPE; HERPES SIMPLEX VIRUS; NONHUMAN; PH; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; VIRION; VIRUS ENTRY; VIRUS PARTICLE; WILD TYPE;

ANIMALS; CELLS, CULTURED; CERCOPITHECUS AETHIOPS; CHO CELLS; CRICETINAE; CRICETULUS; HERPES SIMPLEX; HUMANS; IMMEDIATE-EARLY PROTEINS; SIMPLEXVIRUS; TISSUE DISTRIBUTION; TRANSGENES; VERO CELLS; VIRION;

EID: 84881169464     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0070889     Document Type: Article

References (33)

1. Roizman B, Knipe DM, Whitley RJ (2007) Herpes simplex viruses. In: Knipe DM, Howley PM, editors. Fields Virology: Lipincott Williams & Wilkins. 2501-2602.
2. Kelly BJ, Fraefel C, Cunningham AL, Diefenbach RJ, (2009) Functional roles of the tegument proteins of herpes simplex virus type 1. Virus research 145: 173-186.
3. Yao F, Courtney RJ, (1989) A major transcriptional regulatory protein (ICP4) of herpes simplex virus type 1 is associated with purified virions. Journal of Virology 63: 3338-3344.
4. Yao F, Courtney RJ, (1992) Association of ICP0 but not ICP27 with purified virions of herpes simplex virus type 1. J Virol 66: 2709-2716.
5. Loret S, Guay G, Lippe R, (2008) Comprehensive characterization of extracellular herpes simplex virus type 1 virions. Journal of Virology 82: 8605-8618.
6. Sedlackova L, Rice SA, (2008) Herpes simplex virus type 1 immediate-early protein ICP27 is required for efficient incorporation of ICP0 and ICP4 into virions. J Virol 82: 268-277.
7. Delboy MG, Siekavizza-Robles CR, Nicola AV, (2010) Herpes simplex virus tegument ICP0 is capsid associated, and its E3 ubiquitin ligase domain is important for incorporation into virions. Journal of Virology 84: 1637-1640.
8. Maringer K, Elliott G, (2010) Recruitment of herpes simplex virus type 1 immediate-early protein ICP0 to the virus particle. Journal of Virology 84: 4682-4696.
9. Radtke K, Kieneke D, Wolfstein A, Michael K, Steffen W, et al. (2010) Plus- and minus-end directed microtubule motors bind simultaneously to herpes simplex virus capsids using different inner tegument structures. PLoS pathogens 6: e1000991.
10. Delboy MG, Nicola AV (2011) A pre-immediate early role for tegument ICP0 in the proteasome-dependent entry of herpes simplex virus. Journal of virology.
11. Loret S, Lippe R, (2012) Biochemical analysis of infected cell polypeptide (ICP)0, ICP4, UL7 and UL23 incorporated into extracellular herpes simplex virus type 1 virions. The Journal of general virology 93: 624-634.
12. Courtney RJ, Benyesh-Melnick M, (1974) Isolation and characterization of a large molecular-weight polypeptide of herpes simplex virus type 1. Virology 62: 539-551.
13. DeLuca NA (2011) Functions and mechanism of action of the herpes simplex virus regulatory protein, ICP4. In: Weller SK, editor. Alphaherpesviruses: Molecular Virology. Norfolk, UK: Caister Academic Press. 17-38.
14. Knipe DM, Smith JL, (1986) A mutant herpesvirus protein leads to a block in nuclear localization of other viral proteins. Molecular and cellular biology 6: 2371-2381.
15. Knipe DM, Senechek D, Rice SA, Smith JL, (1987) Stages in the nuclear association of the herpes simplex virus transcriptional activator protein ICP4. Journal of Virology 61: 276-284.
16. Gu B, Rivera-Gonzalez R, Smith CA, DeLuca NA, (1993) Herpes simplex virus infected cell polypeptide 4 preferentially represses Sp1-activated over basal transcription from its own promoter. Proceedings of the National Academy of Sciences of the United States of America 90: 9528-9532.
17. Smith CA, Bates P, Rivera-Gonzalez R, Gu B, DeLuca NA, (1993) ICP4, the major transcriptional regulatory protein of herpes simplex virus type 1, forms a tripartite complex with TATA-binding protein and TFIIB. Journal of Virology 67: 4676-4687.
18. Leopardi R, Ward PL, Ogle WO, Roizman B, (1997) Association of herpes simplex virus regulatory protein ICP22 with transcriptional complexes containing EAP, ICP4, RNA polymerase II, and viral DNA requires posttranslational modification by the U(L)13 proteinkinase. Journal of Virology 71: 1133-1139.
19. DeLuca NA, McCarthy AM, Schaffer PA, (1985) Isolation and characterization of deletion mutants of herpes simplex virus type 1 in the gene encoding immediate-early regulatory protein ICP4. J Virol 56: 558-570.
20. DeLuca NA, Schaffer PA, (1987) Activities of herpes simplex virus type 1 (HSV-1) ICP4 genes specifying nonsense peptides. Nucleic Acids Research 15: 4491-4511.
21. Geraghty RJ, Krummenacher C, Cohen GH, Eisenberg RJ, Spear PG, (1998) Entry of alphaherpesviruses mediated by poliovirus receptor-related protein 1 and poliovirus receptor. Science 280: 1618-1620.
22. Brown SM, Ritchie DA, Subak-Sharpe JH, (1973) Genetic studies with herpes simplex virus type 1. The isolation of temperature-sensitive mutants, their arrangement into complementation groups and recombination analysis leading to a linkage map. The Journal of general virology 18: 329-346.
23. Stow ND, Stow EC, (1986) Isolation and characterization of a herpes simplex virus type 1 mutant containing a deletion within the gene encoding the immediate early polypeptide Vmw110. J Gen Virol 67 (Pt 12): 2571-2585.
24. Cai W, Schaffer PA, (1992) Herpes simplex virus type 1 ICP0 regulates expression of immediate-early, early, and late genes in productively infected cells. Journal of Virology 66: 2904-2915.
25. Su YH, Zhang X, Wang X, Fraser NW, Block TM, (2006) Evidence that the immediate-early gene product ICP4 is necessary for the genome of the herpes simplex virus type 1 ICP4 deletion mutant strain d120 to circularize in infected cells. Journal of Virology 80: 11589-11597.
26. Zhu Z, Cai W, Schaffer PA, (1994) Cooperativity among herpes simplex virus type 1 immediate-early regulatory proteins: ICP4 and ICP27 affect the intracellular localization of ICP0. Journal of Virology 68: 3027-3040.
27. Zhu Z, DeLuca NA, Schaffer PA, (1996) Overexpression of the herpes simplex virus type 1 immediate-early regulatory protein, ICP27, is responsible for the aberrant localization of ICP0 and mutant forms of ICP4 in ICP4 mutant virus-infected cells. Journal of Virology 70: 5346-5356.
28. Eisenberg RJ, Atanasiu D, Cairns TM, Gallagher JR, Krummenacher C, et al. (2012) Herpes virus fusion and entry: a story with many characters. Viruses 4: 800-832.
29. Connolly SA, Jackson JO, Jardetzky TS, Longnecker R, (2011) Fusing structure and function: a structural view of the herpesvirus entry machinery. Nature reviews Microbiology 9: 369-381.
30. Quinlan MP, Knipe DM, (1985) Stimulation of expression of a herpes simplex virus DNA-binding protein by two viral functions. Mol Cell Biol 5: 957-963.
31. Delboy MG, Roller DG, Nicola AV, (2008) Cellular proteasome activity facilitates herpes simplex virus entry at a postpenetration step. J Virol 82: 3381-3390.
32. Nicola AV, McEvoy AM, Straus SE, (2003) Roles for endocytosis and low pH in herpes simplex virus entry into HeLa and Chinese hamster ovary cells. J Virol 77: 5324-5332.
33. Dollery SJ, Delboy MG, Nicola AV, (2010) Low pH-induced conformational change in herpes simplex virus glycoprotein B. J Virol. 84: 3759-3766.