Hypospadias and maternal intake of phytoestrogens

American Journal of Epidemiology

Volumn 178, Issue 3, 2013, Pages 434-440

  Carmichael, Suzan L ^a   Cogswell, Mary E ^b   Ma, Chen ^a   Gonzalez Feliciano, Amparo ^c   Olney, Richard S ^d   Correa, Adolfo ^d,e   Shaw, Gary M ^a  

^a STANFORD UNIVERSITY   (United States)

^b CENTERS FOR DISEASE CONTROL AND PREVENTION   (United States)

^c SCIENCE APPLICATIONS INTERNATIONAL CORPORATION   (United States)

^d NATIONAL CENTER ON BIRTH DEFECTS AND DEVELOPMENTAL DISABILITIES   (United States)

^e UNIVERSITY OF MISSISSIPPI MEDICAL CENTER   (United States)

Author keywords

birth defects; diet; hypospadias; nutrition; phytoestrogen

Indexed keywords

DAIDZEIN; GENISTEIN; ISOFLAVONE DERIVATIVE; LIGNAN; PHYTOESTROGEN; SECOISOLARICIRESINOL;

DISEASE CONTROL; ESTROGENIC COMPOUND; METABOLISM; PARTICIPATORY APPROACH; RISK FACTOR;

ADULT; ARTICLE; CASE CONTROL STUDY; DIETARY INTAKE; ESTROGEN METABOLISM; FEMALE; FOOD FREQUENCY QUESTIONNAIRE; HUMAN; HYPOSPADIAS; MAJOR CLINICAL STUDY; NUTRITION;

BIRTH DEFECTS; DIET; HYPOSPADIAS; NUTRITION; PHYTOESTROGEN;

ADULT; BUTYLENE GLYCOLS; CASE-CONTROL STUDIES; DIET, VEGETARIAN; FEMALE; GENISTEIN; HUMANS; HYPOSPADIAS; INFANT, NEWBORN; ISOFLAVONES; LIGNANS; MALE; ODDS RATIO; PHYTOESTROGENS; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS; QUESTIONNAIRES; RISK ASSESSMENT; RISK FACTORS;

EID: 84881167498     PISSN: 00029262     EISSN: 14766256     Source Type: Journal    
DOI: 10.1093/aje/kws591     Document Type: Article

References (42)

1. Carmichael SL, Shaw GM, Lammer EJ. Environmental and genetic contributors to hypospadias: a review of the epidemiologic evidence. Birth Defects Res A Clin Mol Teratol. 2012;94(7):499-510.
2. Yucel S, Cavalcanti AG, Desouza A, et al. The effect of oestrogen and testosterone on the urethral seam of the developing male mouse genital tubercle. BJU Int. 2003; 92(9):1016-1021.
3. Kim KS, Torres CR Jr, Yucel S, et al. Induction of hypospadias in a murine model by maternal exposure to synthetic estrogens. Environ Res. 2004;94(3): 267-275.
4. Gray LE Jr, Ostby J, Furr J, et al. Toxicant-induced hypospadias in the male rat. Adv Exp Med Biol. 2004;545:217-241.
5. Hsieh MH, Grantham EC, Liu B, et al. In utero exposure to benzophenone-2 causes hypospadias through an estrogen receptor dependent mechanism. J Urol. 2007;178(4 Pt 2): 1637-1642.
6. North K, Golding J. A maternal vegetarian diet in pregnancy is associated with hypospadias. The ALSPAC Study Team. Avon Longitudinal Study of Pregnancy and Childhood. BJU Int. 2000;85(1):107-113.
7. Pierik FH, Burdorf A, Deddens JA, et al. Maternal and paternal risk factors for cryptorchidism and hypospadias: a case-control study in newborn boys. Environ Health Perspect. 2004;112(15):1570-1576.
8. Brouwers MM, Feitz WF, Roelofs LA, et al. Risk factors for hypospadias. Eur J Pediatr. 2006;166(7):671-678.
9. Giordano F, Carbone P, Nori F, et al. Maternal diet and the risk of hypospadias and cryptorchidism in the offspring. Paediatr Perinat Epidemiol. 2008;22(3):249-260.
10. Ormond G, Nieuwenhuijsen MJ, Nelson P, et al. Endocrine disruptors in the workplace, hair spray, folate supplementation, and risk of hypospadias: case-control study. Environ Health Perspect. 2009;117(2):303-307.
11. Carmichael SL, Ma C, Feldkamp ML, et al. Nutritional factors and hypospadias risks. Paediatr Perinat Epidemiol. 2012; 26(4):353-360.
12. Akre O, Boyd HA, Ahlgren M, et al. Maternal and gestational risk factors for hypospadias. Environ Health Perspect. 2008;116(8):1071-1076.
13. Adlercreutz H. Lignans and human health. Crit Rev Clin Lab Sci. 2007;44(5-6):483-525.
14. Vilela ML,Willingham E, Buckley J, et al. Endocrine disruptors and hypospadias: role of genistein and the fungicide vinclozolin. Urology. 2007;70(3):618-621.
15. Levy JR, Faber KA, Ayyash L, et al. The effect of prenatal exposure to the phytoestrogen genistein on sexual differentiation in rats. Proc Soc Exp Biol Med. 1995; 208(1):60-66.
16. Xu X, Duncan AM, Merz BE, et al. Effects of soy isoflavones on estrogen and phytoestrogen metabolism in premenopausal women. Cancer Epidemiol Biomarkers Prev. 1998;7(12): 1101-1108.
17. Bradlow HL, Jernstrom H, Sepkovic DW, et al. Comparison of plasma and urinary levels of 2-hydroxyestrogen and 16-hydroxyestrogen metabolites. Mol Genet Metab. 2006; 87(3):135-146.
18. Walcott FL, Hauptmann M, Duphorne CM, et al. A casecontrol study of dietary phytoestrogens and testicular cancer risk. Nutr Cancer. 2002;44(1):44-51.
19. Setchell KD. Soy isoflavones-benefits and risks from nature's selective estrogen receptor modulators (SERMs). J Am Coll Nutr. 2001;20(5 suppl):354S-362S.
20. Yoon PW, Rasmussen SA, Lynberg MC, et al. The National Birth Defect Prevention Study. Public Health Rep. 2001; 116(suppl 2):32-40.
21. Rasmussen SA, Olney RS, Holmes LB, et al. Guidelines for case classification for the National Birth Defects Prevention Study. Birth Defects Res A Clin Mol Teratol. 2003;67(3): 193-201.
22. Willett WC, Sampson L, Stampfer MJ, et al. Reproducibility and validity of a semiquantitative food frequency questionnaire. Am J Epidemiol. 1985;122(1):51-65.
23. Agricultural Research Service, Department of Agriculture. USDA national nutrient database for standard reference, release 20.Washington, DC: Department of Agriculture; 2007. (http://www.ars.usda.gov/Services/docs.htm?docid=17476). (Accessed December 13, 2012).
24. Kuhnle GG, Dell-Aquila C, Aspinall SM, et al. Phytoestrogen content of beverages, nuts, seeds, and oils. J Agric Food Chem. 2008;56(16):7311-7315.
25. Kuhnle GG, Dell-Aquila C, Aspinall SM, et al. Phytoestrogen content of foods of animal origin: dairy products, eggs, meat, fish, and seafood. J Agric Food Chem. 2008;56(21): 10099-10104.
26. Kuhnle GGC, Dell-Aquila C, Aspinall SM, et al. Phytoestrogen content of fruits and vegetables commonly consumed in the UK based on LC-MS and 13C-labelled standards. Food Chem. 2009;116:542-554.
27. Kuhnle GGC, Dell-Aquila C, Aspinall SM, et al. Phytoestrogen content of cereals and cereal-based foods consumed in the UK. Nutr Cancer. 2009;61(3):302-309.
28. Kuhnle GG, Dell-Aquila C, Low YL, et al. Extraction and quantification of phytoestrogens in foods using automated solid-phase extraction and LC/MS/MS. Anal Chem. 2007; 79(23):9234-9239.
29. Carmichael SL, Gonzalez-Feliciano A, Ma C, et al. Estimated dietary phytoestrogen intake and major food sources among women during the year before pregnancy. Nutr J. 2011;10:105.
30. Carmichael SL, YangW, Correa A, et al. Hypospadias and intake of nutrients related to one-carbon metabolism. J Urol. 2009;181(1):315-321.
31. Helferich WG, Andrade JE, Hoagland MS. Phytoestrogens and breast cancer: a complex story. Inflammopharmacology. 2008;16(5):219-226.
32. Cano A, Garcia-Perez MA, Tarin JJ. Isoflavones and cardiovascular disease. Maturitas. 2010;67(3):219-226.
33. Ward HA, Kuhnle GG, Mulligan AA, et al. Breast, colorectal, and prostate cancer risk in the European Prospective Investigation into Cancer and Nutrition-Norfolk in relation to phytoestrogen intake derived from an improved database. Am J Clin Nutr. 2010;91(2):440-448.
34. Nanri A, Mizoue T, Takahashi Y, et al. Soy product and isoflavone intakes are associated with a lower risk of type 2 diabetes in overweight Japanese women. J Nutr. 2010; 140(3):580-586.
35. Park SY, Murphy SP, Wilkens LR, et al. Legume and isoflavone intake and prostate cancer risk: The Multiethnic Cohort Study. Int J Cancer. 2008;123(4):927-932.
36. Harper A, Kerr DJ, Gescher A, et al. Antioxidant effects of isoflavonoids and lignans, and protection against DNA oxidation. Free Radic Res. 1999;31(2):149-160.
37. Zhao H, Liang J, Li X, et al. Folic acid and soybean isoflavone combined supplementation protects the post-neural tube closure defects of rodents induced by cyclophosphamide in vivo and in vitro. Neurotoxicology. 2010;31(2):180-187.
38. Xing L, Xu Y, Xiao Y, et al. Embryotoxic and teratogenic effects of the combination of bisphenol A and genistein on in vitro cultured postimplantation rat embryos. Toxicol Sci. 2010;115(2):577-588.
39. Jefferson WN, Padilla-Banks E, Goulding EH, et al. Neonatal exposure to genistein disrupts ability of female mouse reproductive tract to support preimplantation embryo development and implantation. Biol Reprod. 2009;80(3):425-431.
40. Ruhlen RL, Howdeshell KL, Mao J, et al. Low phytoestrogen levels in feed increase fetal serum estradiol resulting in the "fetal estrogenization syndrome" and obesity in CD-1 mice. Environ Health Perspect. 2008;116(3):322-328.
41. French MR, Thompson LU, Hawker GA. Validation of a phytoestrogen food frequency questionnaire with urinary concentrations of isoflavones and lignan metabolites in premenopausal women. J Am Coll Nutr. 2007;26(1):76-82.
42. Heald CL, Bolton-Smith C, Ritchie MR, et al. Phyto-oestrogen intake in Scottish men: use of serum to validate a selfadministered food-frequency questionnaire in older men. Eur J Clin Nutr. 2006;60(1):129-135.