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Volumn 65, Issue 4, 2013, Pages 597-608

Enhanced suppression of proliferation and migration in highly-metastatic lung cancer cells by combination of valproic acid and coumarin-3-carboxylic acid and its molecular mechanisms of action

Author keywords

Coumarin 3 carboxylic acid; EGFR VEGFR2 c Met Akt NF B pathways; Lung cancer cells; Proliferation and migration; Valproic acid

Indexed keywords

CASPASE 3; COUMARIN 3 CARBOXYLIC ACID; COUMARIN DERIVATIVE; CYCLIN D1; CYTOCHROME C; I KAPPA B; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1; PROTEIN BAX; PROTEIN BCL 2; PROTEIN KINASE B; SCATTER FACTOR RECEPTOR; UNCLASSIFIED DRUG; VALPROIC ACID;

EID: 84881139063     PISSN: 09209069     EISSN: 15730778     Source Type: Journal    
DOI: 10.1007/s10616-012-9513-7     Document Type: Article
Times cited : (12)

References (38)
  • 1
    • 0036721055 scopus 로고    scopus 로고
    • Anti-tumor mechanisms of valproate: A novel role for an old drug
    • 10.1002/med.10017 1:CAS:528:DC%2BD38XntFSls74%3D
    • Blaheta RA, Cinatl J Jr (2002) Anti-tumor mechanisms of valproate: a novel role for an old drug. Med Res Rev 22:492-511
    • (2002) Med Res Rev , vol.22 , pp. 492-511
    • Blaheta, R.A.1    Cinatl Jr., J.2
  • 2
    • 67349285166 scopus 로고    scopus 로고
    • Differential effects of valproic acid on growth, proliferation and metastasis in HTB5 and HTB9 bladder cancer cell lines
    • 10.1016/j.canlet.2009.02.045 1:CAS:528:DC%2BD1MXnsFajs7c%3D
    • Byun SS, Kim FJ, Khandrika L, Kumar B, Koul S, Wilson S, Koul HK (2009) Differential effects of valproic acid on growth, proliferation and metastasis in HTB5 and HTB9 bladder cancer cell lines. Cancer Lett 281:196-202
    • (2009) Cancer Lett , vol.281 , pp. 196-202
    • Byun, S.S.1    Kim, F.J.2    Khandrika, L.3    Kumar, B.4    Koul, S.5    Wilson, S.6    Koul, H.K.7
  • 3
    • 80053130009 scopus 로고    scopus 로고
    • Histone deacetylase inhibitor valproic acid suppresses the growth and increases the androgen responsiveness of prostate cancer cells
    • 10.1016/j.canlet.2011.07.015 1:CAS:528:DC%2BC3MXht1agtbbK
    • Chou YW, Chaturvedi NK, Ouyang S, Lin FF, Kaushik D, Wang J, Kim I, Lin MF (2011) Histone deacetylase inhibitor valproic acid suppresses the growth and increases the androgen responsiveness of prostate cancer cells. Cancer Lett 311:177-186
    • (2011) Cancer Lett , vol.311 , pp. 177-186
    • Chou, Y.W.1    Chaturvedi, N.K.2    Ouyang, S.3    Lin, F.F.4    Kaushik, D.5    Wang, J.6    Kim, I.7    Lin, M.F.8
  • 5
    • 84867871427 scopus 로고    scopus 로고
    • Low dosed interferon alpha augments the anti-tumor potential of histone deacetylase inhibition on prostate cancer cell growth and invasion
    • Hudak L, Tezeeh P, Wedel S, Makarević J, Juengel E, Tsaur I, Bartsch G, Wiesner C, Haferkamp A, Blaheta RA (2012) Low dosed interferon alpha augments the anti-tumor potential of histone deacetylase inhibition on prostate cancer cell growth and invasion. Prostate 72(16):1719-1735
    • (2012) Prostate , vol.72 , Issue.16 , pp. 1719-1735
    • Hudak, L.1
  • 8
    • 78651518059 scopus 로고    scopus 로고
    • Effects of bufalin on the proliferation of human lung cancer cells and its molecular mechanisms of action
    • Jiang Y, Zhang Y, Luan J, Duan H, Yagasaki K, Zhang G (2010) Effects of bufalin on the proliferation of human lung cancer cells and its molecular mechanisms of action. Cytotechnology 62:578-583
    • (2010) Cytotechnology , vol.62 , pp. 578-583
    • Jiang, Y.1    Zhang, Y.2    Luan, J.3    Duan, H.4    Yagasaki, K.5    Zhang, G.6
  • 9
    • 48849095238 scopus 로고    scopus 로고
    • MicroRNA miR-199a regulates the MET proto-oncogene and the downstream extracellular signal-regulated kinase 2 (ERK2)
    • 10.1074/jbc.M800186200 1:CAS:528:DC%2BD1cXnsVCgu7k%3D
    • Kim S, Lee UJ, Kim MN, Lee EJ, Kim JY, Lee MY, Choung S, Kim YJ, Choi YC (2008a) MicroRNA miR-199a regulates the MET proto-oncogene and the downstream extracellular signal-regulated kinase 2 (ERK2). J Biol Chem 283:18158-18166
    • (2008) J Biol Chem , vol.283 , pp. 18158-18166
    • Kim, S.1    Lee, U.J.2    Kim, M.N.3    Lee, E.J.4    Kim, J.Y.5    Lee, M.Y.6    Choung, S.7    Kim, Y.J.8    Choi, Y.C.9
  • 10
    • 37549050186 scopus 로고    scopus 로고
    • Molecular changes of epidermal growth factor receptor (EGFR) and KRAS and their impact on the clinical outcomes in surgically resected adenocarcinoma of the lung
    • 10.1016/j.lungcan.2007.08.008
    • Kim YT, Kim TY, Lee DS, Park SJ, Park JY, Seo SJ, Choi HS, Kang HJ, Hahn S, Kang CH, Sung SW, Kim JH (2008b) Molecular changes of epidermal growth factor receptor (EGFR) and KRAS and their impact on the clinical outcomes in surgically resected adenocarcinoma of the lung. Lung Cancer 59:111-118
    • (2008) Lung Cancer , vol.59 , pp. 111-118
    • Kim, Y.T.1    Kim, T.Y.2    Lee, D.S.3    Park, S.J.4    Park, J.Y.5    Seo, S.J.6    Choi, H.S.7    Kang, H.J.8    Hahn, S.9    Kang, C.H.10    Sung, S.W.11    Kim, J.H.12
  • 11
    • 84862793621 scopus 로고    scopus 로고
    • Anti-mitotic potential of 7-diethylamino-3(2′-benzoxazolyl)- coumarin in 5-fluorouracil-resistant human gastric cancer cell line SNU620/5-FU
    • 10.1016/j.bbrc.2012.01.049 1:CAS:528:DC%2BC38XitFyitbo%3D
    • Kim NH, Kim SN, Oh JS, Lee S, Kim YK (2012) Anti-mitotic potential of 7-diethylamino-3(2′-benzoxazolyl)-coumarin in 5-fluorouracil-resistant human gastric cancer cell line SNU620/5-FU. Biochem Biophys Res Commun 418:616-621
    • (2012) Biochem Biophys Res Commun , vol.418 , pp. 616-621
    • Kim, N.H.1    Kim, S.N.2    Oh, J.S.3    Lee, S.4    Kim, Y.K.5
  • 13
    • 84862596071 scopus 로고    scopus 로고
    • Sodium valproate inhibits MDA-MB-231 breast cancer cell migration by upregulating NM23H1 expression
    • 10.4238/2012.January.13.1 1:CAS:528:DC%2BC38XhvVaqsL4%3D
    • Li GF, Qian TL, Li GS, Yang CX, Qin M, Huang J, Sun M, Han YQ (2012) Sodium valproate inhibits MDA-MB-231 breast cancer cell migration by upregulating NM23H1 expression. Genet Mol Res 11:77-86
    • (2012) Genet Mol Res , vol.11 , pp. 77-86
    • Li, G.F.1    Qian, T.L.2    Li, G.S.3    Yang, C.X.4    Qin, M.5    Huang, J.6    Sun, M.7    Han, Y.Q.8
  • 14
    • 67349157539 scopus 로고    scopus 로고
    • Enhancement of esculetin on arsenic trioxide-provoked apoptosis in human leukemia U937 cells
    • 10.1016/j.cbi.2009.01.011 1:CAS:528:DC%2BD1MXltlelsLw%3D
    • Lin TH, Lu FJ, Yin YF, Tseng TH (2009) Enhancement of esculetin on arsenic trioxide-provoked apoptosis in human leukemia U937 cells. Chem Biol Interact 180:61-68
    • (2009) Chem Biol Interact , vol.180 , pp. 61-68
    • Lin, T.H.1    Lu, F.J.2    Yin, Y.F.3    Tseng, T.H.4
  • 15
    • 70449524216 scopus 로고    scopus 로고
    • Effects of theanine on growth of human lung cancer and leukemia cells as well as migration and invasion of human lung cancer cells
    • 10.1007/s10616-009-9223-y 1:CAS:528:DC%2BD1MXhtlCjsLjF
    • Liu Q, Duan H, Luan J, Yagasaki K, Zhang G (2009) Effects of theanine on growth of human lung cancer and leukemia cells as well as migration and invasion of human lung cancer cells. Cytotechnology 59:211-217
    • (2009) Cytotechnology , vol.59 , pp. 211-217
    • Liu, Q.1    Duan, H.2    Luan, J.3    Yagasaki, K.4    Zhang, G.5
  • 16
    • 79951681028 scopus 로고    scopus 로고
    • Inhibitory effects of norcantharidin against human lung cancer cell growth and migration
    • 10.1007/s10616-009-9250-8 1:CAS:528:DC%2BC3cXhsVSisrjE
    • Luan J, Duan H, Liu Q, Yagasaki K, Zhang G (2010) Inhibitory effects of norcantharidin against human lung cancer cell growth and migration. Cytotechnology 62:349-355
    • (2010) Cytotechnology , vol.62 , pp. 349-355
    • Luan, J.1    Duan, H.2    Liu, Q.3    Yagasaki, K.4    Zhang, G.5
  • 19
    • 65249141665 scopus 로고    scopus 로고
    • Clinical and biological effects of valproic acid as a histone deacetylase inhibitor on tumor and surrogate tissues: Phase I/II trial of valproic acid and epirubicin/FEC
    • 10.1158/1078-0432.CCR-08-1930 1:CAS:528:DC%2BD1MXjvVWksLo%3D
    • Munster P, Marchion D, Bicaku E, Lacevic M, Kim J, Centeno B, Daud A, Neuger A, Minton S, Sullivan D (2009) Clinical and biological effects of valproic acid as a histone deacetylase inhibitor on tumor and surrogate tissues: phase I/II trial of valproic acid and epirubicin/FEC. Clin Cancer Res 15:2488-2496
    • (2009) Clin Cancer Res , vol.15 , pp. 2488-2496
    • Munster, P.1    Marchion, D.2    Bicaku, E.3    Lacevic, M.4    Kim, J.5    Centeno, B.6    Daud, A.7    Neuger, A.8    Minton, S.9    Sullivan, D.10
  • 21
    • 0027166048 scopus 로고
    • Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death
    • 10.1016/0092-8674(93)90509-O 1:CAS:528:DyaK3sXms1eqtbs%3D
    • Oltvai ZN, Milliman CL, Korsmeyer SJ (1993) Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death. Cell 74:609-619
    • (1993) Cell , vol.74 , pp. 609-619
    • Oltvai, Z.N.1    Milliman, C.L.2    Korsmeyer, S.J.3
  • 22
    • 77950233381 scopus 로고    scopus 로고
    • Inhibition of bladder tumour growth by histone deacetylase inhibitor
    • 10.1111/j.1464-410X.2009.08795.x 1:CAS:528:DC%2BC3cXmtlGjur0%3D
    • Ozawa A, Tanji N, Kikugawa T, Sasaki T, Yanagihara Y, Miura N, Yokoyama M (2010) Inhibition of bladder tumour growth by histone deacetylase inhibitor. BJU Int 105:1181-1186
    • (2010) BJU Int , vol.105 , pp. 1181-1186
    • Ozawa, A.1    Tanji, N.2    Kikugawa, T.3    Sasaki, T.4    Yanagihara, Y.5    Miura, N.6    Yokoyama, M.7
  • 23
    • 64849086921 scopus 로고    scopus 로고
    • Synergism of EGFR and c-Met pathways, cross-talk and inhibition, in non-small cell lung cancer
    • 10.4103/1477-3163.44372
    • Puri N, Salgia R (2008) Synergism of EGFR and c-Met pathways, cross-talk and inhibition, in non-small cell lung cancer. J Carcinog 7:9
    • (2008) J Carcinog , vol.7 , pp. 9
    • Puri, N.1    Salgia, R.2
  • 25
    • 0031464448 scopus 로고    scopus 로고
    • Bcl-2 family proteins: Regulators of apoptosis and chemoresistance inhematologic malignancies
    • Reed JC (1997) Bcl-2 family proteins: regulators of apoptosis and chemoresistance inhematologic malignancies. Semin Hematol 34:S9-S19
    • (1997) Semin Hematol , vol.34
    • Reed, J.C.1
  • 26
    • 80051580618 scopus 로고    scopus 로고
    • Cancer statistics, 2011: The impact of eliminating socioeconomic and racial disparities on premature cancer deaths
    • 10.3322/caac.20121
    • Siegel R, Ward E, Brawley O, Jemal A (2011) Cancer statistics, 2011: the impact of eliminating socioeconomic and racial disparities on premature cancer deaths. CA Cancer J Clin 61:212-236
    • (2011) CA Cancer J Clin , vol.61 , pp. 212-236
    • Siegel, R.1    Ward, E.2    Brawley, O.3    Jemal, A.4
  • 28
    • 0034615555 scopus 로고    scopus 로고
    • Caspases-controlling intracellular signals by protease zymogen activation
    • 10.1016/S0167-4838(99)00281-2 1:CAS:528:DC%2BD3cXhsFGktbk%3D
    • Stennicke HR, Salvesen GS (2000) Caspases-controlling intracellular signals by protease zymogen activation. Biochim Biophys Acta 1477:299-306
    • (2000) Biochim Biophys Acta , vol.1477 , pp. 299-306
    • Stennicke, H.R.1    Salvesen, G.S.2
  • 29
    • 0029858387 scopus 로고    scopus 로고
    • TNF- and cancer therapy-induced apoptosis: Potentiation by inhibition of NF-kappaB
    • 10.1126/science.274.5288.784 1:CAS:528:DyaK28XmsFOhu7Y%3D
    • Wang CY, Mayo MW, Baldwin AS Jr (1996) TNF- and cancer therapy-induced apoptosis: potentiation by inhibition of NF-kappaB. Science 274:784-787
    • (1996) Science , vol.274 , pp. 784-787
    • Wang, C.Y.1    Mayo, M.W.2    Baldwin Jr., A.S.3
  • 30
    • 70449669190 scopus 로고    scopus 로고
    • Suppression of growth, migration and invasion of highly-metastatic human breast cancer cells by berbamine and its molecular mechanisms of action
    • 10.1186/1476-4598-8-81
    • Wang S, Liu Q, Zhang Y, Liu K, Yu P, Liu K, Luan J, Duan H, Lu Z, Wang F, Wu E, Yagasaki K, Zhang G (2009) Suppression of growth, migration and invasion of highly-metastatic human breast cancer cells by berbamine and its molecular mechanisms of action. Mol Cancer 8:81
    • (2009) Mol Cancer , vol.8 , pp. 81
    • Wang, S.1    Liu, Q.2    Zhang, Y.3    Liu, K.4    Yu, P.5    Liu, K.6    Luan, J.7    Duan, H.8    Lu, Z.9    Wang, F.10    Wu, E.11    Yagasaki, K.12    Zhang, G.13
  • 31
    • 80052030406 scopus 로고    scopus 로고
    • Molecular targeting of prostate cancer cells by a triple drug combination down-regulates integrin driven adhesion processes, delays cell cycle progression and interferes with the cdk-cyclin axis
    • 10.1186/1471-2407-11-375 1:CAS:528:DC%2BC3MXht1SqtrbL
    • Wedel S, Hudak L, Seibel JM, Makarević J, Juengel E, Tsaur I, Waaga-Gasser A, Haferkamp A, Blaheta RA (2011) Molecular targeting of prostate cancer cells by a triple drug combination down-regulates integrin driven adhesion processes, delays cell cycle progression and interferes with the cdk-cyclin axis. BMC Cancer 11:375
    • (2011) BMC Cancer , vol.11 , pp. 375
    • Wedel, S.1    Hudak, L.2    Seibel, J.M.3    Makarević, J.4    Juengel, E.5    Tsaur, I.6    Waaga-Gasser, A.7    Haferkamp, A.8    Blaheta, R.A.9
  • 32
    • 0036968347 scopus 로고    scopus 로고
    • Activation of the PI3K/Akt pathway and chemotherapeutic resistance
    • 10.1016/S1368-7646(02)00120-6 1:CAS:528:DC%2BD3sXhtlShtbg%3D
    • West KA, Castillo SS, Dennis PA (2002) Activation of the PI3K/Akt pathway and chemotherapeutic resistance. Drug Resist Updat 5:234-248
    • (2002) Drug Resist Updat , vol.5 , pp. 234-248
    • West, K.A.1    Castillo, S.S.2    Dennis, P.A.3
  • 33
    • 70449534614 scopus 로고    scopus 로고
    • Matrine suppresses breast cancer cell proliferation and invasion via VEGF-Akt-NF-kappaB signaling
    • 10.1007/s10616-009-9225-9 1:CAS:528:DC%2BD1MXhtlCjsLjJ
    • Yu P, Liu Q, Liu K, Yagasaki K, Wu E, Zhang G (2009) Matrine suppresses breast cancer cell proliferation and invasion via VEGF-Akt-NF-kappaB signaling. Cytotechnology 59:219-229
    • (2009) Cytotechnology , vol.59 , pp. 219-229
    • Yu, P.1    Liu, Q.2    Liu, K.3    Yagasaki, K.4    Wu, E.5    Zhang, G.6
  • 34
    • 0034434393 scopus 로고    scopus 로고
    • Induction of apoptosis and cell cycle arrest in cancer cells by in vivo metabolites of teas
    • 10.1207/S15327914NC382-16 1:CAS:528:DC%2BD3MXmsF2hsLo%3D
    • Zhang G, Miura Y, Yagasaki K (2000) Induction of apoptosis and cell cycle arrest in cancer cells by in vivo metabolites of teas. Nutr Cancer 38:265-273
    • (2000) Nutr Cancer , vol.38 , pp. 265-273
    • Zhang, G.1    Miura, Y.2    Yagasaki, K.3
  • 35
    • 70449533764 scopus 로고    scopus 로고
    • Effects of matrine against the growth of human lung cancer and hepatoma cells as well as lung cancer cell migration
    • 10.1007/s10616-009-9211-2 1:CAS:528:DC%2BD1MXhtlCjsLjE
    • Zhang Y, Zhang H, Yu P, Liu Q, Liu K, Duan H, Luan G, Yagasaki K, Zhang G (2009) Effects of matrine against the growth of human lung cancer and hepatoma cells as well as lung cancer cell migration. Cytotechnology 59:191-200
    • (2009) Cytotechnology , vol.59 , pp. 191-200
    • Zhang, Y.1    Zhang, H.2    Yu, P.3    Liu, Q.4    Liu, K.5    Duan, H.6    Luan, G.7    Yagasaki, K.8    Zhang, G.9
  • 36
    • 80053315736 scopus 로고    scopus 로고
    • Valproic acid inhibits prostate cancer cell migration by up-regulating E-cadherin expression
    • Zhang L, Wang G, Wang L, Song C, Wang X, Kang J (2011) Valproic acid inhibits prostate cancer cell migration by up-regulating E-cadherin expression. Pharmazie 66:614-618
    • (2011) Pharmazie , vol.66 , pp. 614-618
    • Zhang, L.1    Wang, G.2    Wang, L.3    Song, C.4    Wang, X.5    Kang, J.6
  • 38
    • 85027921991 scopus 로고    scopus 로고
    • VPA inhibits breast cancer cell migration by specifically targeting HDAC2 and down-regulating Survivin
    • 10.1007/s11010-011-1085-x 1:CAS:528:DC%2BC3MXhs1Oqsr%2FF
    • Zhang L, Wang G, Wang L, Song C, Leng Y, Wang X, Kang J (2012b) VPA inhibits breast cancer cell migration by specifically targeting HDAC2 and down-regulating Survivin. Mol Cell Biochem 361:39-45
    • (2012) Mol Cell Biochem , vol.361 , pp. 39-45
    • Zhang, L.1    Wang, G.2    Wang, L.3    Song, C.4    Leng, Y.5    Wang, X.6    Kang, J.7


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