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Volumn 2, Issue 4, 2013, Pages

Systems pharmacology models for guiding drug design

Author keywords

[No Author keywords available]

Indexed keywords

CHIMERIC PROTEIN; EPIDERMAL GROWTH FACTOR RECEPTOR; MEMBRANE RECEPTOR;

EID: 84881138736     PISSN: None     EISSN: 21638306     Source Type: Journal    
DOI: 10.1038/psp.2013.15     Document Type: Note
Times cited : (4)

References (10)
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    • Mathematical model for the effects of epidermal growth factor receptor trafficking dynamics on fibroblast proliferation responses
    • Starbuck, C. & Lauffenburger, D.A. Mathematical model for the effects of epidermal growth factor receptor trafficking dynamics on fibroblast proliferation responses. Biotechnol. Prog. 8, 132-143 (1992).
    • (1992) Biotechnol. Prog , vol.8 , pp. 132-143
    • Starbuck, C.1    Lauffenburger, D.A.2
  • 3
    • 0033570090 scopus 로고    scopus 로고
    • Quantification of short term signaling by the epidermal growth factor receptor
    • Kholodenko, B.N., Demin, O.V., Moehren, G. & Hoek, J.B. Quantification of short term signaling by the epidermal growth factor receptor. J. Biol. Chem. 274, 30169-30181 (1999).
    • (1999) J. Biol. Chem , vol.274 , pp. 30169-30181
    • Kholodenko, B.N.1    Demin, O.V.2    Moehren, G.3    Hoek, J.B.4
  • 4
    • 77049220618 scopus 로고
    • Affinity and intrinsic activity in the theory of competitive inhibition. I. Problems and theory
    • Ariens, E.J. Affinity and intrinsic activity in the theory of competitive inhibition. I. Problems and theory. Arch. Int. Pharmacodyn. Ther. 99, 32-49 (1954).
    • (1954) Arch. Int. Pharmacodyn. Ther , vol.99 , pp. 32-49
    • Ariens, E.J.1
  • 5
    • 0021058380 scopus 로고
    • Operational models of pharmacological agonism
    • Black, J.W. & Leff, P. Operational models of pharmacological agonism. Proc. R. Soc. Lond., B, Biol. Sci. 220, 141-162 (1983).
    • (1983) Proc. R. Soc. Lond., B, Biol. Sci , vol.220 , pp. 141-162
    • Black, J.W.1    Leff, P.2
  • 6
    • 0030842321 scopus 로고    scopus 로고
    • Analysis of drug-receptor interactions in vivo: A new approach in pharmacokinetic-pharmacodynamic modelling
    • Van der Graaf, P.H. & Danhof, M. Analysis of drug-receptor interactions in vivo: a new approach in pharmacokinetic-pharmacodynamic modelling. Int. J. Clin. Pharmacol. Ther. 35, 442-446 (1997).
    • (1997) Int. J. Clin. Pharmacol. Ther. , vol.35 , pp. 442-446
    • Van Der Graaf, P.H.1    Danhof, M.2
  • 9
    • 43749102294 scopus 로고    scopus 로고
    • Enhancement of cell type specificity by quantitative modulation of a chimeric ligand
    • Cironi, P., Swinburne, I.A. & Silver, P.A. Enhancement of cell type specificity by quantitative modulation of a chimeric ligand. J. Biol. Chem. 283, 8469-8476 (2008).
    • (2008) J. Biol. Chem. , vol.283 , pp. 8469-8476
    • Cironi, P.1    Swinburne, I.A.2    Silver, P.A.3
  • 10
    • 84855382987 scopus 로고    scopus 로고
    • Optimizing properties of antireceptor antibodies using kinetic computational models and experiments
    • Harms, B.D., Kearns, J.D., Su, S.V., Kohli, N., Nielsen, U.B. & Schoeberl, B. Optimizing properties of antireceptor antibodies using kinetic computational models and experiments. Meth. Enzymol. 502, 67-87 (2012)
    • (2012) Meth. Enzymol. , vol.502 , pp. 67-87
    • Harms, B.D.1    Kearns, J.D.2    Su, S.V.3    Kohli, N.4    Nielsen, U.B.5    Schoeberl, B.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.