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Volumn 120, Issue 8, 2013, Pages 1217-1223

Cerebroprotective potential of resveratrol through anti-oxidant and anti-inflammatory mechanisms in rats

Author keywords

Anti inflammatory; Antioxidant; ICAM I; Ischemia reperfusion; Resveratrol

Indexed keywords

BIOLOGICAL MARKER; CATALASE; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 10; INTERLEUKIN 6; MALONALDEHYDE; MYELOPEROXIDASE; RESVERATROL; SUPEROXIDE DISMUTASE; TUMOR NECROSIS FACTOR ALPHA;

EID: 84881111804     PISSN: 03009564     EISSN: 14351463     Source Type: Journal    
DOI: 10.1007/s00702-013-0982-4     Document Type: Article
Times cited : (68)

References (49)
  • 2
    • 6944250259 scopus 로고    scopus 로고
    • Role of resveratrol in prevention and therapy of cancer: Preclinical and clinical studies
    • 1:CAS:528:DC%2BD2cXhtVSjsLrK 15517885
    • Aggarwal BB, Bhardwai A, Aggarwal RS, Seeram NP, Shishodia S, Takada Y (2004) Role of resveratrol in prevention and therapy of cancer: preclinical and clinical studies. Anticancer Res 24(5A):2783-27840
    • (2004) Anticancer Res , vol.24 A5 , pp. 2783-27840
    • Aggarwal, B.B.1    Bhardwai, A.2    Aggarwal, R.S.3    Seeram, N.P.4    Shishodia, S.5    Takada, Y.6
  • 3
    • 36749081135 scopus 로고    scopus 로고
    • Resveratrol as an antioxidant and pro-oxidant agent: Mechanisms and clinical implications
    • 10.1042/BST0351156 1:CAS:528:DC%2BD2sXht1eru7vP 17956300
    • Alarcon de la Lastra C, Villegas I (2007) Resveratrol as an antioxidant and pro-oxidant agent: mechanisms and clinical implications. Biochem Soc Trans 35:1156-1160
    • (2007) Biochem Soc Trans , vol.35 , pp. 1156-1160
    • Alarcon De La Lastra, C.1    Villegas, I.2
  • 4
    • 3142655732 scopus 로고    scopus 로고
    • Oxyresveratrol (trans-2, 3′, 4, 5′- tetrahydroxystilbene) is neuroprotective and inhibits the apoptotic cell death in transient cerebral ischemia
    • 10.1016/j.brainres.2004.05.038 1:CAS:528:DC%2BD2cXlsl2jur8%3D 15261105
    • Andrabi SA, Spina MG, Lorenz P, Ebmeyer U, Wolf G, Horn TF (2004) Oxyresveratrol (trans-2, 3′, 4, 5′- tetrahydroxystilbene) is neuroprotective and inhibits the apoptotic cell death in transient cerebral ischemia. Brain Res 1017:98-107
    • (2004) Brain Res , vol.1017 , pp. 98-107
    • Andrabi, S.A.1    Spina, M.G.2    Lorenz, P.3    Ebmeyer, U.4    Wolf, G.5    Horn, T.F.6
  • 5
    • 38549170318 scopus 로고    scopus 로고
    • Neuroprotective effect of Smilacis chinae rhizome on NMDA-induced neurotoxicity in vitro and focal cerebral ischemia in vivo
    • 10.1254/jphs.FP0071206 1:CAS:528:DC%2BD1cXhslGnurk%3D 18202548
    • Ban JY, Cho SO, Choi SH, Ju HS, Kim JY, Bae K, Song KS, Seong YH (2008) Neuroprotective effect of Smilacis chinae rhizome on NMDA-induced neurotoxicity in vitro and focal cerebral ischemia in vivo. J Pharmacol Sci 106(1):68-77
    • (2008) J Pharmacol Sci , vol.106 , Issue.1 , pp. 68-77
    • Ban, J.Y.1    Cho, S.O.2    Choi, S.H.3    Ju, H.S.4    Kim, J.Y.5    Bae, K.6    Song, K.S.7    Seong, Y.H.8
  • 6
    • 0022483434 scopus 로고
    • Rat middle cerebral artery occlusion: Evaluation of the model and development of a neurologic examination
    • 10.1161/01.STR.17.3.472 1:STN:280:DyaL283js1Gktw%3D%3D 3715945
    • Bederson JB, Pitts LH, Tsuji M, Nishimura MC, Davis RL, Bartkowski H (1986) Rat middle cerebral artery occlusion: evaluation of the model and development of a neurologic examination. Stroke 17:472-476
    • (1986) Stroke , vol.17 , pp. 472-476
    • Bederson, J.B.1    Pitts, L.H.2    Tsuji, M.3    Nishimura, M.C.4    Davis, R.L.5    Bartkowski, H.6
  • 8
    • 0030917448 scopus 로고    scopus 로고
    • Amelioration of oxidative stress by antioxidant and resveratrol in PC12 cells
    • 10.1097/00001756-199704140-00035 1:CAS:528:DyaK2sXjvVOhurc%3D 9172162
    • Chanvitayapongs S, Draczynska LB, Sun AY (1997) Amelioration of oxidative stress by antioxidant and resveratrol in PC12 cells. Neuroreport 8:1499-1502
    • (1997) Neuroreport , vol.8 , pp. 1499-1502
    • Chanvitayapongs, S.1    Draczynska, L.B.2    Sun, A.Y.3
  • 9
    • 33847774731 scopus 로고    scopus 로고
    • Resveratrol: Ready for prime time?
    • 10.1016/j.yjmcc.2006.11.014 1:CAS:528:DC%2BD2sXislKhu70%3D 17222864
    • Dawn B (2007) Resveratrol: ready for prime time? J Mol Cell Cardiol 42(3):484-486
    • (2007) J Mol Cell Cardiol , vol.42 , Issue.3 , pp. 484-486
    • Dawn, B.1
  • 10
    • 0030760110 scopus 로고    scopus 로고
    • Microvascular responses to cerebral ischemia/inflammation
    • 10.1111/j.1749-6632.1997.tb48386.x 9292040
    • Del Zoppo GJ (1997) Microvascular responses to cerebral ischemia/inflammation. Ann NY Acad Sci 823:132-147
    • (1997) Ann NY Acad Sci , vol.823 , pp. 132-147
    • Del Zoppo, G.J.1
  • 11
    • 62249110887 scopus 로고    scopus 로고
    • Resveratrol pretreatment protects rat brain from cerebral ischemic damage via a sirtuin 1-uncoupling protein 2 pathway
    • 10.1016/j.neuroscience.2009.01.017 1:CAS:528:DC%2BD1MXjsVKqsrw%3D 19356683
    • Della-Morte D, Dave KR, DeFazio RA, Bao YC, Raval AP, Perez-Pinzon MA (2009) Resveratrol pretreatment protects rat brain from cerebral ischemic damage via a sirtuin 1-uncoupling protein 2 pathway. Neuroscience 159:993-1002
    • (2009) Neuroscience , vol.159 , pp. 993-1002
    • Della-Morte, D.1    Dave, K.R.2    Defazio, R.A.3    Bao, Y.C.4    Raval, A.P.5    Perez-Pinzon, M.A.6
  • 12
    • 43049135853 scopus 로고    scopus 로고
    • Stroke
    • 10.1016/S0140-6736(08)60694-7 1:CAS:528:DC%2BD1cXlslWhsbY%3D 18468545
    • Donnan GA, Fisher M, Macleod M, Davis SM (2008) Stroke. Lancet 371:1612-1623
    • (2008) Lancet , vol.371 , pp. 1612-1623
    • Donnan, G.A.1    Fisher, M.2    Macleod, M.3    Davis, S.M.4
  • 13
    • 54049114757 scopus 로고    scopus 로고
    • ICAM-1: Role in inflammation and in the regulation of vascular permeability
    • 10.1152/ajpheart.00779.2008 1:CAS:528:DC%2BD1cXhtFCgt7nO 18689494
    • Frank PG, Lisanti MP (2008) ICAM-1: role in inflammation and in the regulation of vascular permeability. Am J Physiol Heart Circ Physiol 295(3):H926-H927
    • (2008) Am J Physiol Heart Circ Physiol , vol.295 , Issue.3
    • Frank, P.G.1    Lisanti, M.P.2
  • 14
    • 0027791754 scopus 로고
    • Reactive oxygen species and inflammation
    • 1:CAS:528:DyaK2cXhtVensr0%3D
    • Hakim J (1993) Reactive oxygen species and inflammation. CR Seances Soc Biol Fil 187(3):286-295
    • (1993) CR Seances Soc Biol Fil , vol.187 , Issue.3 , pp. 286-295
    • Hakim, J.1
  • 15
    • 0024583778 scopus 로고
    • Forebrain ischemia induced by temporary bilateral common carotid occlusion in normotensive rats
    • 10.1016/0022-510X(89)90098-1 1:STN:280:DyaL1M3lslCntQ%3D%3D 2723680
    • Iwasaki Y, Ito S, Suzuki M, Nagahori T, Yamamato T, Konno H (1989) Forebrain ischemia induced by temporary bilateral common carotid occlusion in normotensive rats. J Neurol Sci 90:155-165
    • (1989) J Neurol Sci , vol.90 , pp. 155-165
    • Iwasaki, Y.1    Ito, S.2    Suzuki, M.3    Nagahori, T.4    Yamamato, T.5    Konno, H.6
  • 17
    • 0021681627 scopus 로고
    • A modified spectrophotometric assay of superoxide dismutase
    • 1:CAS:528:DyaL2cXksFSmsL0%3D
    • Kakkar P, Das B, Viswanathan PN (1984) A modified spectrophotometric assay of superoxide dismutase. Ind J Bio Chem Biophys 21(2):130-132
    • (1984) Ind J Bio Chem Biophys , vol.21 , Issue.2 , pp. 130-132
    • Kakkar, P.1    Das, B.2    Viswanathan, P.N.3
  • 18
    • 0030724437 scopus 로고    scopus 로고
    • Current therapeutic options for brain ischemia
    • 10.1212/WNL.49.5-Suppl-4.S56 1:STN:280:DyaK1c%2FjvVCqsg%3D%3D 9371152
    • Kaste M (1997) Current therapeutic options for brain ischemia. Neurology 49:s56-s59
    • (1997) Neurology , vol.49
    • Kaste, M.1
  • 19
    • 17344371804 scopus 로고    scopus 로고
    • Mitochondrial manganese superoxide dismutase prevents neural apoptosis and reduces ischemic brain injury: Suppression of peroxynitrite production, lipid peroxidation, and mitochondrial dysfunction
    • 1:CAS:528:DyaK1cXlsFajtw%3D%3D 9425011
    • Keller JN, Kindy MS, Holtsberg FW et al (1998) Mitochondrial manganese superoxide dismutase prevents neural apoptosis and reduces ischemic brain injury: suppression of peroxynitrite production, lipid peroxidation, and mitochondrial dysfunction. J Neurosci 18(2):687-697
    • (1998) J Neurosci , vol.18 , Issue.2 , pp. 687-697
    • Keller, J.N.1    Kindy, M.S.2    Holtsberg, F.W.3
  • 20
    • 2342562573 scopus 로고    scopus 로고
    • Administration of N-acetylcysteine after focal cerebral ischemia protects brain and reduces inflammation in a rat model of experimental stroke
    • 10.1002/jnr.20087 1:CAS:528:DC%2BD2cXjvVyjtrw%3D 15114624
    • Khan M, Siphon B, Jatana M, Giri S, Gilg AG, Sekhon C, Singh AK (2004) Administration of N-acetylcysteine after focal cerebral ischemia protects brain and reduces inflammation in a rat model of experimental stroke. J Neurosci Res 76(4):519-527
    • (2004) J Neurosci Res , vol.76 , Issue.4 , pp. 519-527
    • Khan, M.1    Siphon, B.2    Jatana, M.3    Giri, S.4    Gilg, A.G.5    Sekhon, C.6    Singh, A.K.7
  • 21
    • 0030684021 scopus 로고    scopus 로고
    • Experimental models of cerebral ischemia
    • 1:STN:280:DyaK1c%2Fot1Ggug%3D%3D 9420968
    • Kim HK (1997) Experimental models of cerebral ischemia. Acta Anaesthesiol Scand Suppl 111:91-92
    • (1997) Acta Anaesthesiol Scand Suppl , vol.111 , pp. 91-92
    • Kim, H.K.1
  • 22
    • 33748310632 scopus 로고    scopus 로고
    • Effect of resveratrol on 3-nitropropionic acid-induced biochemical and behavioral changes: Possible neuroprotective mechanisms
    • 10.1097/00008877-200609000-00014 1:CAS:528:DC%2BD28XoslOnt7k%3D 16940769
    • Kumar P, Padi SS, Naidu PS, Kumar A (2006) Effect of resveratrol on 3-nitropropionic acid-induced biochemical and behavioral changes: possible neuroprotective mechanisms. Behav Pharmacol 17:485-492
    • (2006) Behav Pharmacol , vol.17 , pp. 485-492
    • Kumar, P.1    Padi, S.S.2    Naidu, P.S.3    Kumar, A.4
  • 23
    • 71049180369 scopus 로고    scopus 로고
    • Inflammatory mechanisms in ischemic stroke: Therapeutic approaches
    • 10.1186/1479-5876-7-97 19919699
    • Lakhan SE, Kirchgessner A, Hfer M (2009) Inflammatory mechanisms in ischemic stroke: therapeutic approaches. J Transl Med 7:97
    • (2009) J Transl Med , vol.7 , pp. 97
    • Lakhan, S.E.1    Kirchgessner, A.2    Hfer, M.3
  • 24
    • 79958719815 scopus 로고    scopus 로고
    • The acetylation of RelA in Lys310 dictates the NF-κB-dependent response in post-ischemic injury
    • 10.1038/cddis.2010.76 1:STN:280:DC%2BC3M3jsVWnsg%3D%3D 21368872
    • Lanzillotta A, Sarnico I, Ingrassia R et al (2010) The acetylation of RelA in Lys310 dictates the NF-κB-dependent response in post-ischemic injury. Cell Death Dis 1:e96
    • (2010) Cell Death Dis , vol.1 , pp. 96
    • Lanzillotta, A.1    Sarnico, I.2    Ingrassia, R.3
  • 25
    • 84866317962 scopus 로고    scopus 로고
    • Rat Pial microvascular responses to transient bilateral common carotid artery occlusion and reperfusion: Quercetin's mechanism of action
    • 1:CAS:528:DC%2BC38XptFamsLY%3D 22557973
    • Lapi D, Vagnani S, Pignataro G, Esposito E, Paterni M, Colantuoni A (2012) Rat Pial microvascular responses to transient bilateral common carotid artery occlusion and reperfusion: Quercetin's mechanism of action. Front Physiol 3:99
    • (2012) Front Physiol , vol.3 , pp. 99
    • Lapi, D.1    Vagnani, S.2    Pignataro, G.3    Esposito, E.4    Paterni, M.5    Colantuoni, A.6
  • 26
    • 68549098095 scopus 로고    scopus 로고
    • Expression of IL-10 and TNF-alpha in rats with cerebral infarction after transplantation with mesenchymal stem cells
    • 10.1038/cmi.2009.28 19567204
    • Liu N, Chen R, Du H, Wang J, Zhang Y, Wen J (2009) Expression of IL-10 and TNF-alpha in rats with cerebral infarction after transplantation with mesenchymal stem cells. Cell Mol Immunol 6:207-213
    • (2009) Cell Mol Immunol , vol.6 , pp. 207-213
    • Liu, N.1    Chen, R.2    Du, H.3    Wang, J.4    Zhang, Y.5    Wen, J.6
  • 27
    • 79251601931 scopus 로고    scopus 로고
    • Resveratrol improves neuron protection and functional recovery in rat model of spinal cord injury
    • 10.1016/j.brainres.2010.11.061 1:CAS:528:DC%2BC3MXhtlaitLY%3D 21111721
    • Liu C, Shi Z, Fan L, Chen Z, Wang K, Wang B (2011) Resveratrol improves neuron protection and functional recovery in rat model of spinal cord injury. Brain Res 1374:100-109
    • (2011) Brain Res , vol.1374 , pp. 100-109
    • Liu, C.1    Shi, Z.2    Fan, L.3    Chen, Z.4    Wang, K.5    Wang, B.6
  • 28
    • 47849132642 scopus 로고    scopus 로고
    • Resveratrol in prevention and treatment of common clinical conditions of aging
    • 1:CAS:528:DC%2BD1cXpt1WqtLc%3D 18686754
    • Markus MA, Morris BJ (2008) Resveratrol in prevention and treatment of common clinical conditions of aging. Clin Interv Aging 3(2):331-339
    • (2008) Clin Interv Aging , vol.3 , Issue.2 , pp. 331-339
    • Markus, M.A.1    Morris, B.J.2
  • 29
    • 84881094741 scopus 로고    scopus 로고
    • Gemfibrozil pretreatment affecting antioxidant defense system and inflammatory, but not Nrf-2 signaling pathways resulted in female neuroprotection and male neurotoxicity in the rat models of global cerebral ischemia-reperfusion
    • Mohagheghi F, Khalaj L, Ahmadiani A, Rahmani B (2012) Gemfibrozil pretreatment affecting antioxidant defense system and inflammatory, but not Nrf-2 signaling pathways resulted in female neuroprotection and male neurotoxicity in the rat models of global cerebral ischemia-reperfusion. Neurotox Res (Epub ahead of print)
    • (2012) Neurotox Res (Epub Ahead of Print)
    • Mohagheghi, F.1    Khalaj, L.2    Ahmadiani, A.3    Rahmani, B.4
  • 30
    • 33847363051 scopus 로고    scopus 로고
    • Protective effect of biflavones from Araucaria bidwillii Hook in rat cerebral ischemia/reperfusion induced oxidative stress
    • 10.1016/j.bbr.2006.12.025 1:CAS:528:DC%2BD2sXislWjsL8%3D 17250903
    • Mukherjee PK, Ahamed KF, Kumar V, Mukherjee K, Houghton PJ (2007) Protective effect of biflavones from Araucaria bidwillii Hook in rat cerebral ischemia/reperfusion induced oxidative stress. Behav Brain Res 178:221-228
    • (2007) Behav Brain Res , vol.178 , pp. 221-228
    • Mukherjee, P.K.1    Ahamed, K.F.2    Kumar, V.3    Mukherjee, K.4    Houghton, P.J.5
  • 31
    • 0021998590 scopus 로고
    • Myeloperoxidase activity as a quantitative assessment of neutrophil infiltration into lschemic myocardium
    • 10.1016/0160-5402(85)90029-4 1:CAS:528:DyaL2MXmtFamu7s%3D 2997548
    • Mullane KM, Bruce Smith ND (1985) Myeloperoxidase activity as a quantitative assessment of neutrophil infiltration into lschemic myocardium. J Pharmacol Methods 14:157-167
    • (1985) J Pharmacol Methods , vol.14 , pp. 157-167
    • Mullane, K.M.1    Bruce Smith, N.D.2
  • 32
    • 84862177952 scopus 로고    scopus 로고
    • Possible involvement of oxidative stress and inflammatory mediators in the protective effects of the early preconditioning window against transient global ischemia in rats
    • 10.1007/s11064-011-0651-7 1:CAS:528:DC%2BC3MXhsFensrbL 22113727
    • Nassar NN, Abdelsalam RM, Abdel-Rahman AA, Abdallah DM (2012) Possible involvement of oxidative stress and inflammatory mediators in the protective effects of the early preconditioning window against transient global ischemia in rats. Neurochem Res 37(3):614-621
    • (2012) Neurochem Res , vol.37 , Issue.3 , pp. 614-621
    • Nassar, N.N.1    Abdelsalam, R.M.2    Abdel-Rahman, A.A.3    Abdallah, D.M.4
  • 33
    • 0018384650 scopus 로고
    • Assay of lipid peroxides in animal tissue by thiobarbituric acid reaction
    • 10.1016/0003-2697(79)90738-3
    • Okhawa H, Ohishi N, Yagi K (1979) Assay of lipid peroxides in animal tissue by thiobarbituric acid reaction. Anal Biochem 95:351-358
    • (1979) Anal Biochem , vol.95 , pp. 351-358
    • Okhawa, H.1    Ohishi, N.2    Yagi, K.3
  • 34
    • 61449205308 scopus 로고    scopus 로고
    • Resveratrol inhibits tumor cell adhesion to endothelial cells by blocking ICAM-1 expression
    • 1:CAS:528:DC%2BD1MXjtFGgtrg%3D 19331173
    • Park JS, Kim KM, Kim MH, Chang HJ, Baek MK (2009) Resveratrol inhibits tumor cell adhesion to endothelial cells by blocking ICAM-1 expression. Anticancer Res 29(1):355-362
    • (2009) Anticancer Res , vol.29 , Issue.1 , pp. 355-362
    • Park, J.S.1    Kim, K.M.2    Kim, M.H.3    Chang, H.J.4    Baek, M.K.5
  • 35
    • 0033029454 scopus 로고    scopus 로고
    • Protein kinase C-activated oxidant generation in endothelial cells signals intercellular adhesion molecule-1 gene transcription
    • 1:CAS:528:DyaK1MXhslWju70%3D 10051543
    • Rahman A, Bando M, Kefer J, Anwar KN, Malik AB (1999) Protein kinase C-activated oxidant generation in endothelial cells signals intercellular adhesion molecule-1 gene transcription. Mol Pharmacol 55(3):575-583
    • (1999) Mol Pharmacol , vol.55 , Issue.3 , pp. 575-583
    • Rahman, A.1    Bando, M.2    Kefer, J.3    Anwar, K.N.4    Malik, A.B.5
  • 36
    • 0029670016 scopus 로고    scopus 로고
    • Early increases in TNF-alpha, IL-6 and IL-1 beta following transient cerebral ischemia in gerbil brain
    • 10.1016/S0304-3940(96)12460-5 1:CAS:528:DyaK28XhvVKqs7o%3D 8710173
    • Saito K, Suyama K, Nishida K, Sei Y, Basile AS (1996) Early increases in TNF-alpha, IL-6 and IL-1 beta following transient cerebral ischemia in gerbil brain. Neurosci Lett 206:149-152
    • (1996) Neurosci Lett , vol.206 , pp. 149-152
    • Saito, K.1    Suyama, K.2    Nishida, K.3    Sei, Y.4    Basile, A.S.5
  • 37
    • 0037189154 scopus 로고    scopus 로고
    • Protective effect of resveratrol against oxidative stress in middle cerebral artery occlusion model of stroke in rats
    • 10.1016/S0024-3205(02)01691-0 1:CAS:528:DC%2BD38XksFKnsrY%3D 12072154
    • Sinha K, chaudhary G, Gupta YK (2002) Protective effect of resveratrol against oxidative stress in middle cerebral artery occlusion model of stroke in rats. Life Sci 71:655-665
    • (2002) Life Sci , vol.71 , pp. 655-665
    • Sinha, K.1    Chaudhary, G.2    Gupta, Y.K.3
  • 38
    • 39449083733 scopus 로고    scopus 로고
    • Antioxidants and free radical scavengers for the treatment of stroke, traumatic brain injury and aging
    • 10.2174/092986708783497337 1:CAS:528:DC%2BD1cXnsVyisL8%3D 18288995
    • Slemmer JE, Shacka JJ, Sweeney MI, Weber JT (2008) Antioxidants and free radical scavengers for the treatment of stroke, traumatic brain injury and aging. Curr Med Chem 15(4):404-414
    • (2008) Curr Med Chem , vol.15 , Issue.4 , pp. 404-414
    • Slemmer, J.E.1    Shacka, J.J.2    Sweeney, M.I.3    Weber, J.T.4
  • 40
    • 34547101726 scopus 로고    scopus 로고
    • Resveratrol alleviates cardiac dysfunction in streptozotocin-induced diabetes: Role of nitric oxide, thioredoxin, and heme oxygenase
    • 10.1016/j.freeradbiomed.2007.05.004 1:CAS:528:DC%2BD2sXotlSmsL8%3D 17664136
    • Thirunavukkarasu M, Penumathsa SV, Koneru S et al (2007) Resveratrol alleviates cardiac dysfunction in streptozotocin-induced diabetes: role of nitric oxide, thioredoxin, and heme oxygenase. Free Radic Biol Med 43(5):720-729
    • (2007) Free Radic Biol Med , vol.43 , Issue.5 , pp. 720-729
    • Thirunavukkarasu, M.1    Penumathsa, S.V.2    Koneru, S.3
  • 41
    • 0021837237 scopus 로고
    • Actinomycin D suppresses the protective effect of dexamethasone in rats affected by global cerebral ischemia
    • 10.1161/01.STR.16.3.501 1:CAS:528:DyaL2MXltlGgtbw%3D 4002266
    • Tosaki A, Koltai M, Joo F, Adam G et al (1985) Actinomycin D suppresses the protective effect of dexamethasone in rats affected by global cerebral ischemia. Stroke 16(3):501-505
    • (1985) Stroke , vol.16 , Issue.3 , pp. 501-505
    • Tosaki, A.1    Koltai, M.2    Joo, F.3    Adam, G.4
  • 42
    • 0027960320 scopus 로고
    • Treatment with ranitidine of ischemic brain edema
    • 10.1016/0014-2999(94)00546-X 1:CAS:528:DyaK2cXmvFalsbw%3D 7698188
    • Tosaki A, Szerdahelyi P, Joo F (1994) Treatment with ranitidine of ischemic brain edema. Eur J Pharmacol 264(3):455-458
    • (1994) Eur J Pharmacol , vol.264 , Issue.3 , pp. 455-458
    • Tosaki, A.1    Szerdahelyi, P.2    Joo, F.3
  • 43
    • 33749646867 scopus 로고    scopus 로고
    • Significance of wine and resveratrol in cardiovascular disease: French paradox revisited
    • 1:CAS:528:DC%2BD28XhtF2lsLrI 18651034
    • Vidavalur R, Otani H, Singal PK, Singal MN (2006) Significance of wine and resveratrol in cardiovascular disease: French paradox revisited. Exp Clin Cardiol 11(3):217-225
    • (2006) Exp Clin Cardiol , vol.11 , Issue.3 , pp. 217-225
    • Vidavalur, R.1    Otani, H.2    Singal, P.K.3    Singal, M.N.4
  • 44
    • 0033993607 scopus 로고    scopus 로고
    • Partial neuroprotection of in vivo excitotoxic brain damage by chronic administration of the red wine antioxidant agent, trans resveratrol in rats
    • 10.1016/S0304-3940(00)00820-X 1:CAS:528:DC%2BD3cXhsVahtLk%3D 10704758
    • Virgili M, Contestabile A (2000) Partial neuroprotection of in vivo excitotoxic brain damage by chronic administration of the red wine antioxidant agent, trans resveratrol in rats. Neurosci Lett 281(2-3):123-126
    • (2000) Neurosci Lett , vol.281 , Issue.2-3 , pp. 123-126
    • Virgili, M.1    Contestabile, A.2
  • 45
    • 0037184675 scopus 로고    scopus 로고
    • Resveratrol protects against global cerebral ischemic injury in gerbils
    • 10.1016/S0006-8993(02)03543-6 1:CAS:528:DC%2BD38XptFeks7s%3D 12470882
    • Wang Q, Xu J, Rottinghaus GE, Simonyi A, Lubahn D, Sun GY, Sun AY (2002) Resveratrol protects against global cerebral ischemic injury in gerbils. Brain Res 958(2):439-447
    • (2002) Brain Res , vol.958 , Issue.2 , pp. 439-447
    • Wang, Q.1    Xu, J.2    Rottinghaus, G.E.3    Simonyi, A.4    Lubahn, D.5    Sun, G.Y.6    Sun, A.Y.7
  • 46
    • 39049169272 scopus 로고    scopus 로고
    • Modulation of neuro-inflammation and vascular response by oxidative stress following cerebral ischemia-reperfusion injury
    • 10.2174/092986708783330665 1:CAS:528:DC%2BD1cXnsVyju74%3D 18220759
    • Wong CH, Crack PJ (2008) Modulation of neuro-inflammation and vascular response by oxidative stress following cerebral ischemia-reperfusion injury. Curr Med Chem 15(1):1-14
    • (2008) Curr Med Chem , vol.15 , Issue.1 , pp. 1-14
    • Wong, C.H.1    Crack, P.J.2
  • 47
    • 34147152673 scopus 로고    scopus 로고
    • Selenium plays a modulatory role against cerebral ischemia-induced neuronal damage in rat hippocampus
    • 10.1016/j.brainres.2007.01.143 1:CAS:528:DC%2BD2sXksVOqt7g%3D 17376411
    • Yousuf S, Atif F, Ahmad M, Hoda MN, Khan MB, Ishrat T, Islam F (2007) Selenium plays a modulatory role against cerebral ischemia-induced neuronal damage in rat hippocampus. Brain Res 1147:218-225
    • (2007) Brain Res , vol.1147 , pp. 218-225
    • Yousuf, S.1    Atif, F.2    Ahmad, M.3    Hoda, M.N.4    Khan, M.B.5    Ishrat, T.6    Islam, F.7
  • 48
    • 58149279285 scopus 로고    scopus 로고
    • Resveratrol exerts its neuroprotective effect by modulating mitochondrial dysfunctions and associated cell death during cerebral ischemia
    • 10.1016/j.brainres.2008.10.068 1:CAS:528:DC%2BD1MXkt1Wjug%3D%3D 19027723
    • Yousuf S, Atif F, Ahmad M, Hoda N, Ishrat T, Khan B, Islam F (2009) Resveratrol exerts its neuroprotective effect by modulating mitochondrial dysfunctions and associated cell death during cerebral ischemia. Brain Res 1250:242-253
    • (2009) Brain Res , vol.1250 , pp. 242-253
    • Yousuf, S.1    Atif, F.2    Ahmad, M.3    Hoda, N.4    Ishrat, T.5    Khan, B.6    Islam, F.7
  • 49
    • 77952674793 scopus 로고    scopus 로고
    • Anti-inflammatory activities of resveratrol in the brain: Role of resveratrol in microglial activation
    • 10.1016/j.ejphar.2010.03.043 1:CAS:528:DC%2BC3cXlvVaqurs%3D 20361959
    • Zhang F, Liu J, Shi JS (2010) Anti-inflammatory activities of resveratrol in the brain: role of resveratrol in microglial activation. Eur J Pharmacol 636:1-7
    • (2010) Eur J Pharmacol , vol.636 , pp. 1-7
    • Zhang, F.1    Liu, J.2    Shi, J.S.3


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