Effects of surgery, general anesthesia, and perioperative epidural analgesia on the immune function of patients with non-small cell lung cancer

Journal of Clinical Anesthesia

Volumn 25, Issue 4, 2013, Pages 255-262

  Cata, Juan P ^a   Bauer, Maria ^b   Sokari, Telemate ^c   Ramirez, María F ^a   Mason, David ^d   Plautz, Gregory ^d   Kurz, Andrea ^d  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^b WEILL CORNELL MEDICAL COLLEGE   (United States)

^c BAYLOR COLLEGE OF MEDICINE   (United States)

^d LERNER RESEARCH INSTITUTE   (United States)

Author keywords

Analgesia, epidural; Anesthesia; Innate immunity; Lung cancer; Natural killers non small cell lung cancer

Indexed keywords

BUPIVACAINE; FENTANYL; GAMMA INTERFERON; INTERLEUKIN 2; INTERLEUKIN 4; NITROGEN; SEVOFLURANE;

ARTICLE; ARTIFICIAL VENTILATION; BISPECTRAL INDEX; CANCER SURGERY; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CYTOTOXIC T LYMPHOCYTE; EPIDURAL ANESTHESIA; GENERAL ANESTHESIA; HELPER CELL; INNATE IMMUNITY; LUNG NON SMALL CELL CANCER; NATURAL KILLER T CELL; OBSERVATIONAL STUDY; PAIN ASSESSMENT; POSTOPERATIVE ANALGESIA; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; THORACOTOMY;

ANALGESIA, EPIDURAL; ANESTHESIA; INNATE IMMUNITY; LUNG CANCER; NATURAL KILLERS NON-SMALL CELL LUNG CANCER;

AGED; ANALGESIA, EPIDURAL; ANALGESICS, OPIOID; ANESTHESIA, GENERAL; CARCINOMA, NON-SMALL-CELL LUNG; CONSCIOUSNESS MONITORS; CYTOKINES; FEMALE; FENTANYL; HUMANS; IMMUNITY, INNATE; LUNG NEOPLASMS; MALE; METHYL ETHERS; MIDDLE AGED; NATURAL KILLER T-CELLS; PAIN, POSTOPERATIVE; POSTOPERATIVE PERIOD;

EID: 84881089492     PISSN: 09528180     EISSN: 18734529     Source Type: Journal    
DOI: 10.1016/j.jclinane.2012.12.007     Document Type: Article

References (44)

1. J.P. Desborough The stress response to trauma and surgery Br J Anaesth 85 2000 109 117
2. J.P. Cata, V. Gottumukkala, and D.I. Sessler How regional anesthesia might reduce postoperative cancer recurrence Eur J Pain Suppl 5 2011 345 355
3. D.I. Sessler, A. Kurz, and R. Lenhardt Re: Hypothermia reduces resistance to surgical wound infections Am Surg 65 1999 1193 1196
4. K. Greenfeld, R. Avraham, and M. Benish Immune suppression while awaiting surgery and following it: dissociations between plasma cytokine levels, their induced production, and NK cell cytotoxicity Brain Behav Immun 21 2007 503 513
5. E. Tønnesen, K. Höhndorf, G. Lerbjerg, N.J. Christensen, M.S. Hüttel, and K. Andersen Immunological and hormonal responses to lung surgery during one-lung ventilation Eur J Anaesthesiol 10 1993 189 195
6. D.I. Sessler, S. Ben-Eliyahu, E.J. Mascha, M.O. Parat, and D.J. Buggy Can regional analgesia reduce the risk of recurrence after breast cancer? Methodology of a multicenter randomized trial Contemp Clin Trials 29 2008 517 526
7. D.I. Sessler Does regional analgesia reduce the risk of cancer recurrence? A hypothesis Eur J Cancer Prev 17 2008 269 272
8. L.M. Bradley, D.K. Dalton, and M. Croft A direct role for IFN-gamma in regulation of Th1 cell development J Immunol 157 1996 1350 1358
9. W. Liao, J.X. Lin, and W.J. Leonard IL-2 family cytokines: new insights into the complex roles of IL-2 as a broad regulator of T helper cell differentiation Curr Opin Immunol 23 2011 598 604
10. J.I. Ellyard, L. Simson, and C.R. Parish Th2-mediated anti-tumour immunity: friend or foe? Tissue Antigens 70 2007 1 11
11. Y.F. Han, J. Zhao, and L.Y. Ma Factors predicting occurrence and prognosis of hepatitis-B-virus-related hepatocellular carcinoma World J Gastroenterol 17 2011 4258 4270
12. C. Woiciechowsky, K. Asadullah, and D. Nestler Sympathetic activation triggers systemic interleukin-10 release in immunodepression induced by brain injury Nat Med 4 1998 808 813
13. J.T. Di Piro, T.R. Howdieshell, J.K. Goddard, D.B. Callaway, R.G. Hamilton, and A.R. Mansberger Jr. Association of interleukin-4 plasma levels with traumatic injury and clinical course Arch Surg 130 1995 1159 1163
14. B.F. Zamarron, and W. Chen Dual roles of immune cells and their factors in cancer development and progression Int J Biol Sci 7 2011 651 658
15. B. Ruffell, D.G. DeNardo, N.I. Affara, and L.M. Coussens Lymphocytes in cancer development: polarization towards pro-tumor immunity Cytokine Growth Factor Rev 21 2010 3 10
16. S. Motohashi, and T. Nakayama Invariant natural killer T cell-based immunotherapy for cancer Immunotherapy 1 2009 73 82
17. N. Kobayashi, S. Usui, and S. Kikuchi Preoperative lymphocyte count is an independent prognostic factor in node-negative non-small cell lung cancer Lung Cancer 75 2012 223 227
18. A.K. Exadaktylos, D.J. Buggy, D.C. Moriarty, E. Mascha, and D.I. Sessler Can anesthetic technique for primary breast cancer surgery affect recurrence or metastasis? Anesthesiology 105 2006 660 664
19. T. Volk, U.R. Döpfmer, and M. Schmutzler Stress induced IL-10 does not seem to be essential for early monocyte deactivation following cardiac surgery Cytokine 24 2003 237 243
20. H. Wada, S. Seki, and T. Takahashi Combined spinal and general anesthesia attenuates liver metastasis by preserving TH1/TH2 cytokine balance Anesthesiology 106 2007 499 506
21. T. Volk, M. Schenk, K. Voigt, S. Tohtz, M. Putzier, and W.J. Kox Postoperative epidural anesthesia preserves lymphocyte, but not monocyte, immune function after major spine surgery Anesth Analg 98 2004 1086 1092
22. I. Conrick-Martin, M.R. Kell, and D.J. Buggy Meta-analysis of the effect of central neuraxial regional anesthesia compared with general anesthesia on postoperative natural killer T lymphocyte function J Clin Anesth 24 2012 3 7
23. M. Vitale, L.M. Neri, and S. Comani Natural killer function in flow cytometry. II. Evaluation of NK lytic activity by means of target cell morphological changes detected by right angle light scatter J Immunol Methods 121 1989 115 120
24. M.N. Norazmi, and S. Suarn Disparity in the percentage of CD4 + T lymphocytes and prognosis of HIV-infected intravenous drug users in Malaysia Immunol Lett 43 1994 177 182
25. C.S. Ng, T.W. Lee, and S. Wan Thoracotomy is associated with significantly more profound suppression in lymphocytes and natural killer cells than video-assisted thoracic surgery following major lung resections for cancer J Invest Surg 18 2005 81 88
26. G. Vanni, F. Tacconi, F. Sellitri, V. Ambrogi, T.C. Mineo, and E. Pompeo Impact of awake videothoracoscopic surgery on postoperative lymphocyte responses Ann Thorac Surg 90 2010 973 978
27. M. Yokoyama, Y. Itano, and H. Katayama The effects of continuous epidural anesthesia and analgesia on stress response and immune function in patients undergoing radical esophagectomy Anesth Analg 101 2005 1521 1527
28. J.M. Brand, H. Kirchner, C. Poppe, and P. Schmucker The effects of general anesthesia on human peripheral immune cell distribution and cytokine production Clin Immunol Immunopathol 83 1997 190 194
29. B. Beilin, Y. Shavit, and J. Hart Effects of anesthesia based on large versus small doses of fentanyl on natural killer cell cytotoxicity in the perioperative period Anesth Analg 82 1996 492 497
30. S. Bar-Yosef, R. Melamed, G.G. Page, G. Shakhar, K. Shakhar, and S. Ben-Eliyahu Attenuation of the tumor-promoting effect of surgery by spinal blockade in rats Anesthesiology 94 2001 1066 1073
31. M.F. Yuen, R.D. Hughes, M.A. Heneghan, P.G. Langley, and S. Norris Expression of Fas antigen (CD95) in peripheral blood lymphocytes and in liver-infiltrating, cytotoxic lymphocytes in patients with hepatocellular carcinoma Cancer 92 2001 2136 2141
32. S.R. Johnston, D.O. Constenla, and J. Moore Randomized phase II trial of BCDT [carmustine (BCNU), cisplatin, dacarbazine (DTIC) and tamoxifen] with or without interferon alpha (IFN-alpha) and interleukin (IL-2) in patients with metastatic melanoma Br J Cancer 77 1998 1280 1286
33. I. Mrakovcić-Sutić, D. Bacić, S. Golubović, R. Bacić, and M. Marinović Cross-talk between NKT and regulatory T cells (Tregs) in modulation of immune response in patients with colorectal cancer following different pain management techniques Coll Antropol 35 Suppl 2 2011 57 60
34. O. Ahlers, I. Nachtigall, and J. Lenze Intraoperative thoracic epidural anaesthesia attenuates stress-induced immunosuppression in patients undergoing major abdominal surgery Br J Anaesth 101 2008 781 787
35. E.Y. Woo, C.S. Chu, and T.J. Goletz Regulatory CD4(+)CD25(+) T cells in tumors from patients with early-stage non-small cell lung cancer and late-stage ovarian cancer Cancer Res 61 2001 4766 4772
36. A. Neuner, M. Schindel, U. Wildenberg, T. Muley, H. Lahm, and J.R. Fischer Prognostic significance of cytokine modulation in non-small cell lung cancer Int J Cancer 101 2002 287 292
37. M. Chechlińska, A. Duma, K. Swierkowska, J. Kamińska, and J. Steffen Sera of lung cancer patients affect the release of Th1, Th2 and monocyte-derived cytokines, and the expression of IL-2Ralpha by normal, stimulated mononuclear cells Cell Mol Biol Lett 9 2004 69 81
38. G. Wang, Y. Weng, Y. Ishiguro, H. Sakamoto, and S. Morita The effect of tramadol on serum cytokine response in patients undergoing pulmonary lobectomy J Clin Anesth 17 2005 444 450
39. J.Y. Hong, and K.T. Lim Effect of preemptive epidural analgesia on cytokine response and postoperative pain in laparoscopic radical hysterectomy for cervical cancer Reg Anesth Pain Med 33 2008 44 51
40. S. Liu, B. Wang, and S. Li Immune cell populations decrease during craniotomy under general anesthesia Anesth Analg 113 2011 572 577
41. M. Westerterp, M.A. Boermeester, and J.M. Omloo Differential responses of cellular immunity in patients undergoing neoadjuvant therapy followed by surgery for carcinoma of the oesophagus Cancer Immunol Immunother 57 2008 1837 1847
42. A.E. Le Cras, H.F. Galley, and N.R. Webster Spinal but not general anesthesia increases the ratio of T helper 1 to T helper 2 cell subsets in patients undergoing transurethral resection of the prostate Anesth Analg 87 1998 1421 1425
43. C.A. Crane, S.J. Han, J.J. Barry, B.J. Ahn, L.L. Lanier, and A.T. Parsa TGF-beta downregulates the activating receptor NKG2D on NK cells and CD8 + T cells in glioma patients Neuro Oncol 12 2010 7 13
44. C.N. Baxevanis, K. Papilas, G.V. Dedoussis, T. Pavlis, and M. Papamichail Abnormal cytokine serum levels correlate with impaired cellular immune responses after surgery Clin Immunol Immunopathol 71 1994 82 88