Differential responses of cellular immunity in patients undergoing neoadjuvant therapy followed by surgery for carcinoma of the oesophagus

Cancer Immunology, Immunotherapy

Volumn 57, Issue 12, 2008, Pages 1837-1847

  Westerterp, Marinke ^a   Boermeester, Marja A ^a   Omloo, Jikke M T ^a   Hulshof, Maarten C C M ^a   Vervenne, Walter L ^a   Lutter, Rene ^a   Out, Theo A ^a   Van Lanschot, J Jan B ^a  

^a ACADEMIC MEDICAL CENTER   (Netherlands)

Author keywords

Immune response; Neoadjuvant therapy; Oesophageal cancer; Surgery; T cell imbalance

Indexed keywords

CARBOPLATIN; PACLITAXEL;

ADULT; AGED; ARTICLE; BLOOD CELL COUNT; BLOOD SAMPLING; CANCER PATIENT; CANCER RADIOTHERAPY; CELL COUNT; CELLULAR IMMUNITY; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; ESOPHAGUS CARCINOMA; ESOPHAGUS RESECTION; FEMALE; GRANULOCYTE; HUMAN; HYPERTHERMIC THERAPY; LYMPHOCYTE; MALE; POSTOPERATIVE PERIOD; PRIORITY JOURNAL; TH1 CELL; TH2 CELL;

ADULT; AGED; ANTINEOPLASTIC AGENTS; B-LYMPHOCYTES; COMBINED MODALITY THERAPY; ESOPHAGEAL NEOPLASMS; ESOPHAGECTOMY; FEMALE; GRANULOCYTES; HUMANS; KILLER CELLS, NATURAL; LEUKOCYTE COUNT; MALE; MIDDLE AGED; NEOADJUVANT THERAPY; RADIOTHERAPY; T-LYMPHOCYTE SUBSETS; TH1 CELLS; TH2 CELLS;

EID: 52549115548     PISSN: 03407004     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00262-008-0511-8     Document Type: Article

References (44)

1. M Albregts MC Hulshof PJ Zum Vorde Sive Vording 2004 A feasibility study in oesophageal carcinoma using deep loco-regional hyperthermia combined with concurrent chemotherapy followed by surgery Int J Hyperthermia 20 647 659
2. B Autran V Leblond B Sadat-Sowti 1991 A soluble factor released by CD8+CD57+ lymphocytes from bone marrow transplanted patients inhibits cell-mediated cytolysis Blood 77 2237 2241
3. H von Boehmer P Kisielow 1993 Lymphocyte lineage commitment: instruction versus selection Cell 73 207 208
4. JE Brinchmann JH Dobloug BH Heger 1994 Expression of costimulatory molecule CD28 on T cells in human immunodeficiency virus type 1 infection: functional and clinical correlations J Infect Dis 169 730 738
5. IB Brune W Wilke T Hensler 1999 Downregulation of T helper type 1 immune response and altered pro-inflammatory and anti-inflammatory T cell cytokine balance following conventional but not laparoscopic surgery Am J Surg 177 55 60
6. D Decker M Schondorf F Bidlingmaier 1996 Surgical stress induces a shift in the type-1/type-2 T-helper cell balance, suggesting down-regulation of cell-mediated and up-regulation of antibody-mediated immunity commensurate to the trauma Surgery 119 316 325
7. G Del Prete M De Carli F Almerigogna 1993 Human IL-10 is produced by both type 1 helper (Th1) and type 2 helper (Th2) T cell clones and inhibits their antigen-specific proliferation and cytokine production J Immunol 150 353 360
8. Dijk van JDP, Gonzalez Gonzalez D, Blank LECM (eds) (1989) Deep local hyperthermia with a four aperture array system of large waveguide radiators: results of simulation and clinical application. Hyperthermic oncology, vol 1. Taylor & Francis, London, pp 573-575
9. R Earlam JR Cunha-Melo 1980 Oesophageal squamous cell carcinomas: II. A critical view of radiotherapy Br J Surg 67 457 461
10. J Galon A Costes F Sanchez-Cabo 2006 Type, density, and location of immune cells within human colorectal tumors predict clinical outcome Science 313 1960 1964
11. G Gorochov P Debre V Leblond 1994 Oligoclonal expansion of CD8+CD57+ T cells with restricted T-cell receptor beta chain variability after bone marrow transplantation Blood 83 587 595
12. CD Heidecke H Weighardt M Feith 2002 Neoadjuvant treatment of esophageal cancer: immunosuppression following combined radiochemotherapy Surgery 132 495 501
13. T Hensler H Hecker K Heeg 1997 Distinct mechanisms of immunosuppression as a consequence of major surgery Infect Immun 65 2283 2291
14. SB Hosch AJ Meyer C Schneider 1997 Expression and prognostic significance of HLA class I, ICAM-1, and tumor-infiltrating lymphocytes in esophageal cancer J Gastrointest Surg 1 316 323
15. RS Hotchkiss SB Osmon KC Chang 2005 Accelerated lymphocyte death in sepsis occurs by both the death receptor and mitochondrial pathways J Immunol 174 5110 5118
16. RS Hotchkiss KW Tinsley PE Swanson 2001 Sepsis-induced apoptosis causes progressive profound depletion of B and CD4+ T lymphocytes in humans J Immunol 166 6952 6963
17. R Iyer N Wilkinson T Demmy M Javle 2004 Controversies in the multimodality management of locally advanced esophageal cancer: evidence-based review of surgery alone and combined-modality therapy Ann Surg Oncol 11 665 673
18. RA Kempf MS Mitchell 1985 Effects of chemotherapeutic agents on the immune response: II Cancer Invest 3 23 33
19. CL Mackall TA Fleisher MR Brown 1997 Distinctions between CD8+ and CD4+ T-cell regenerative pathways result in prolonged T-cell subset imbalance after intensive chemotherapy Blood 89 3700 3707
20. K Mafune Y Tanaka 2000 Influence of multimodality therapy on the cellular immunity of patients with esophageal cancer Ann Surg Oncol 7 609 616
21. AM Mandard F Dalibard JC Mandard 1994 Pathologic assessment of tumor regression after preoperative chemoradiotherapy of esophageal carcinoma: clinicopathologic correlations Cancer 73 2680 2686
22. A Mantovani W Luini G Peri 1978 Effect of chemotherapeutic agents on natural cell-mediated cytotoxicity in mice J Natl Cancer Inst 61 1255 1261
23. Medical Research Council Oesophageal Cancer Working 2002 Surgical resection with or without preoperative chemotherapy in oesophageal cancer: a randomised controlled trial Lancet 359 1727 1733
24. RD Moses SO Sharrow DA Stephany 1989 Cardiac allograft survival across major histocompatibility complex barriers in the rhesus monkey following T lymphocyte-depleted autologous marrow transplantation. IV: Immune reconstitution Transplantation 48 774 781
25. TR Mosmann RL Coffman 1989 TH1 and TH2 cells: different patterns of lymphokine secretion lead to different functional properties Annu Rev Immunol 7 145 173
26. JM Muller H Erasmi M Stelzner 1990 Surgical therapy of oesophageal carcinoma Br J Surg 77 845 857
27. VV Ostapenko H Tanaka M Miyano 2005 Immune-related effects of local hyperthermia in patients with primary liver cancer Hepatogastroenterology 52 1502 1506
28. F Pages A Berger M Camus 2005 Effector memory T cells, early metastasis, and survival in colorectal cancer N Engl J Med 353 2654 2666
29. B Petrini J Wasserman H Blomgren 1985 T-cell subsets in patients treated with pelvic irradiation for cancer J Clin Lab Immunol 17 147 148
30. DN Posnett R Sinha S Kabak C Russo 1994 Clonal populations of T cells in normal elderly humans: the T cell equivalent to "benign monoclonal gammapathy J Exp Med 179 609 618
31. O Rick J Beyer N Schwella W Siegert 2002 Influence of amifostine on reconstitution of lymphocyte subpopulations after conventional- and high-dose chemotherapy in patients with germ cell tumor Ann Hematol 81 717 722
32. E Robey R Axel 1990 CD4: collaborator in immune recognition and HIV infection Cell 60 697 700
33. S Romagnani 1994 Lymphokine production by human T cells in disease states Annu Rev Immunol 12 227 257
34. P Sansoni A Cossarizza V Brianti 1993 Lymphocyte subsets and natural killer cell activity in healthy old people and centenarians Blood 82 2767 2773
35. K Schumacher W Haensch C Roefzaad PM Schlag 2001 Prognostic significance of activated CD8(+) T cell infiltrations within esophageal carcinomas Cancer Res 61 3932 3936
36. J Stjernsward M Jondal F Vanky 1972 Lymphopenia and change in distribution of human B and T lymphocytes in peripheral blood induced by irradiation for mammary carcinoma Lancet 1 1352 1356
37. H Suzuki JA Punt LG Granger A Singer 1995 Asymmetric signaling requirements for thymocyte commitment to the CD4+ versus CD8+ T cell lineages: a new perspective on thymic commitment and selection Immunity 2 413 425
38. S Szmigielski J Sobczynski G Sokolska 1991 Effects of local prostatic hyperthermia on human NK and T cell function Int J Hyperthermia 7 869 880
39. JT Tan B Ernst WC Kieper 2002 Interleukin (IL)-15 and IL-7 jointly regulate homeostatic proliferation of memory phenotype CD8+ cells but are not required for memory phenotype CD4+ cells J Exp Med 195 1523 1532
40. S Tsutsui K Sonoda K Sumiyoshi 1996 Prognostic significance of immunological parameters in patients with esophageal cancer Hepatogastroenterology 43 501 509
41. JW Van Sandick MA Boermeester SS Gisbertz 2003 Lymphocyte subsets and T(h) 1/T(h) 2 immune responses in patients with adenocarcinoma of the oesophagus or oesophagogastric junction: relation to pTNM stage and clinical outcome Cancer Immunol Immunother 52 617 624
42. JW Van Sandick SS Gisbertz IJ Ten Berge 2003 Immune responses and prediction of major infection in patients undergoing transhiatal or transthoracic esophagectomy for cancer Ann Surg 237 35 43
43. EL Verastegui RB Morales JL Barrera-Franco 2003 Long-term immune dysfunction after radiotherapy to the head and neck area Int Immunopharmacol 3 1093 1104
44. HA Wieder BL Brucher F Zimmermann 2004 Time course of tumor metabolic activity during chemoradiotherapy of esophageal squamous cell carcinoma and response to treatment J Clin Oncol 22 900 908