Evaluation of anti-inflammatory activity, effect on blood pressure & gastric tolerability of antidepressants

Indian Journal of Medical Research

Volumn 138, Issue JUL 2013, 2013, Pages 99-103

  Chugh, Preeta Kaur ^a   Kalra, Bhupinder Singh ^a   Kaushik, Nitin ^a   Tekur, Uma ^a  

^a MAULANA AZAD MEDICAL COLLEGE   (India)

Author keywords

Anti inflammatory; Anti depressants; Paw oedema; Venlafaxine

Indexed keywords

AMITRIPTYLINE; ANTIDEPRESSANT AGENT; CARRAGEENAN; FLUOXETINE; IMIPRAMINE; PRAZOSIN; SODIUM CHLORIDE; VENLAFAXINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BLOOD PRESSURE; BLOOD PRESSURE REGULATION; CONTROLLED STUDY; DRUG DOSE COMPARISON; DRUG SCREENING; DRUG TOLERABILITY; GASTRIC TOLERABILITY; GASTROINTESTINAL TRACT EXAMINATION; NONHUMAN; PAW EDEMA; RAT; SINGLE DRUG DOSE; STOMACH FUNCTION;

ANIMALS; ANTI-INFLAMMATORY AGENTS; ANTIDEPRESSIVE AGENTS; BLOOD PRESSURE; DRUG EVALUATION, PRECLINICAL; RATS; RATS, WISTAR; STOMACH;

EID: 84881035607     PISSN: 09715916     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (27)

1. Maizels M, McCarberg B Antidepressants and antiepileptic drugs for chronic non-cancer pain. Am Fam Physician 2005; 71: 483-90.
2. McQuay HJ, Tramèr M, Nye BA, Carroll D, Wiffen PJ, Moore RA. A systematic review of antidepressants in neuropathic pain. Pain 1996; 68: 217-27.
3. Abdel-Salam OM, Nofal SM, El-Shenawy SM. Evaluation of the anti-inflammatory and anti-nociceptive effects of different antidepressants in the rat. Pharmacol Res 2003; 48: 157-65.
4. Licht CM, de Geus EJ, Seldenrijk A, van Hout HP, Zitman FG, van Dyck, et al. Depression is associated with decreased blood pressure, but antidepressant use increases the risk for hypertension. Hypertension 2009; 53: 631-8.
5. Thase ME. Effects of venlafaxine on blood pressure: a meta-analysis of original data from 3744 depressed patients. J Clin Psychiatry 1998; 59: 502-8.
6. Sawynok J, Esser MJ, Reid AR. Antidepressants as analgesics: an overview of central and peripheral mechanisms of action.J Psychiatry Neurosci 2001; 26: 21-9.
7. Roose SP, Glassman AH, Attia E, Woodring S, Giardina EG, Bigger JT Jr. Cardiovascular effects of fluoxetine in depressed patients with heart disease. Am J Psychiatry 1998; 155: 660-5.
8. Armstrong CP, Blower AL. Non-steroidal anti-inflammatory drugs and life threatening complications of peptic ulceration. Gut 1987; 28: 527-32.
9. de Abajo FJ, Rodríguez LA, Montero D. Association between selective serotonin reuptake inhibitors and upper gastrointestinal bleeding: population based casecontrol study. BMJ 1999; 319: 1106-9.
10. Sharma JN, Samud AM, Asmauei MZ. Comparison between plethysmometer and micrometer methods to measure acute paw oedema for screening anti-inflammatory activity in mice. Inflammopharmacology 2004; 12: 89-94.
11. Kunchandy J, Khanna S, Kulkarni SK. Effect of alpha 2 agonists clonidine, guanfacine and B-HT 920 on gastric acid secretion and ulcers in rats. Arch Int Pharmacodyn Ther 1984; 275: 123-38.
12. Hurwitz EL, Morgenstern H. Cross-sectional associations of asthma, hay fever, and other allergies with major depression and low-back pain among adults aged 20-39 years in the United States. Am J Epidemiol 1999; 150: 1107-16.
13. Kozora E, Ellison MC, West S. Depression, fatigue, and pain in systemic lupus erythematosus (SLE): relationship to the American College of Rheumatology SLE neuropsychological battery. Arthritis Rheum 2006; 55: 628-35.
14. Zielinski TA, Brown ES, Nejtek VA, Khan DA, Moore JJ, Rush AJ. Depression in asthma: Prevalence and clinical implications. Prim Care Companion J Clin Psychiatry 2000; 2: 153-8.
15. Roumestan C, Michel A, Bichon F, Portet K, Detoc M, Henriquet C, et al. Anti-inflammatory properties of desipramine and fluoxetine. Respir Res 2007; 8: 35.
16. Abdel-Salam OM, Baiuomy AR, Arbid MS. Studies on the anti-inflammatory effect of fluoxetine in the rat. Pharmacol Res 2004; 49: 119-31.
17. Faraj BA, Olkowski ZL, Jackson RT. Expression of a high-affinity serotonin transporter in human lymphocytes. Int J Immunopharmacol 1994; 16: 561-7.
18. Marino F, Cosentino M, Bombelli R, Ferrari M, Lecchini S, Frigo G. Endogenous catecholamine synthesis, metabolism storage, and uptake in human peripheral blood mononuclear cells. Exp Hematol 1999; 27: 489-95.
19. Elenkov IJ, Wilder RL, Chrousos GP, Vizi ES. The sympathetic nerve-an integrative interface between two supersystems:the brain and the immune system. Pharmacol Rev 2000;52: 595-638.
20. Abdelmawla AH, Langley RW, Szabadi E, Bradshaw CM.Comparison of the effects of venlafaxine, desipramine, and paroxetine on noradrenaline- and methoxamine-evoked constriction of the dorsal hand vein. Br J Clin Pharmacol 1999; 48: 345-54.
21. Hajhashemi V, Sadeghi H, Minaiyan M, Movahedian A, Talebi A. The role of central mechanisms in the anti-inflammatory effect of amitriptyline on carrageenan-induced paw edema in rats. Clinics (Sao Paulo) 2010; 65: 1183-7.
22. Vismari L, Alves GJ, Palermo-Neto J. Amitriptyline and acute inflammation: a study using intravital microscopy and the carrageenan-induced paw edema model. Pharmacology 2010; 86: 231-9.
23. Lazartigues E, Brefel-Courbon C, Bagheri H, Costes S, Gharib C, Tran MA, et al. Fluoxetine-induced pressor response in freely moving rats: a role for vasopressin and sympathetic tone. Fundam Clin Pharmacol 2000; 14: 443-51.
24. Amsterdam JD, Garcia-Espana F, Fawcett J, Quitkin FM, Reimherr FW, Rosenbaum JF, et al. Blood pressure changes during short-term fluoxetine treatment. J Clin Psychopharmacol 1999; 19: 9-14.
25. Volkers AC, Tulen JH, van den Broek WW, Bruyn JA, Passchier J, Pepplinkhuizen L. Effects of imipramine, fluvoxamine and depressive mood on autonomic cardiac functioning in major depressive disorder. Pharmacopsychiatry 2004; 37: 18-25.
26. Andrade C, Sandarsh S, Chethan KB, Nagesh KS. Serotonin reuptake inhibitor antidepressants and abnormal bleeding: a review for clinicians and a reconsideration of mechanisms.J Clin Psychiatry 2010; 71: 1565-75.
27. de Abajo FJ, García-Rodríguez LA. Risk of upper gastrointestinal tract bleeding associated with selective serotonin reuptake inhibitors and venlafaxine therapy: interaction with nonsteroidal anti-inflammatory drugs and effect of acid-suppressing agents. Arch Gen Psychiatry 2008; 65: 795-803.